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Anomalous origin of left coronary artery from the pulmonary artery (ALCAPA) is a very rare congenital cardiac disorder with an incidence of about 1 in 300000 live births. The majority of patients are symptomatic in early infancy with symptoms of intractable heart failure. Only very few patients survive to adulthood with minimal symptoms. A young female was referred to us in view of breathlessness, clinical examination didn抰 show any signs except a grade 2 systolic murmur in the pulmonary area. The patient underwent 2D echocardiography evaluation which revealed suspicion of ALCAPA and was confirmed using coronary angiography. The patient underwent surgical closure of ALCAPA along with left internal mammary artery (LIMA) to left anterior descending (LAD) anastomosis, postoperative period was uneventful, on routine follow-up the patient is doing well with resolution of dyspnea. ALCAPA is a very rare disorder and most of it is diagnosed in infancy and not many surviving beyond infancy, high degree of suspicion of ALCAPA is needed for young patients presenting with symptoms of angina, heart failure.
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Behcet’s’s disease is a systemic vasculitis involving small to large veins and arteries. It is a sporadic disease, mostly prevalent among the ancestors of the silk route. It is characterized by recurrent oral ulcers, genital ulcers, and uveitis. It also can manifest as skin, vascular, gastrointestinal, neurological, cardiac, and renal involvement. Though overall mortality is around 5%, delay in diagnosis and treatment may lead to significant morbidity. Cardiovascular and pulmonary arterial aneurysms are dreadful complications of this disease. Being uncommon in south India it is liable to be wrongly diagnosed and treated. Delay in the diagnosis and treatment may lead to severe complications. Here we present a case of Behcet’s disease which was managed at primary health care inadequately. We also demonstrated a quick response to steroids which are the mainstay of treatment. In this case presentation we illustrated pre and post treatment scrotal and oral Behcet’s’s lesions for clinicians to memorize. We also discussed international criteria to diagnose Behcet’s disease (ICBD) in concurrence with our case. In this presentation, we briefly described the involvement of other systems and their treatment. This article also elaborated on the latest developments in the treatment of Behcet’s disease.
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Background: Staphylococcus aureus infections are one of the most common and serious hospital-acquired infections seen in developing countries. Methicillin resistant Staphylococcus aureus (MRSA) is an important human pathogen and normally colonized in body parts including skin, nose, perineum and throat. MRSA is resistant not only to all ?-lactam groups but also other antibiotics including aminoglycosides, tetracycline and macrolides. In the present study the efficacy of agents used in the management of MRSA infections was determined by antibiotic gradient testing. Methods: A total of 60 clinical isolates of MRSA strains were collected from various diagnostic labs in central Kerala. Clinical isolates were reconfirmed as MRSA by gram staining, yellow-coloured colonies on mannitol salt Agar (MSA). Antibiotic susceptibility testing was done by disc diffusion method as recommended by CLSI guidelines. S. aureus isolates resistant to cefoxitin (30 µg) was identified as MRSA. Antibiotic gradient testing was performed to determine the MIC of vancomycin, tigecycline, linezolid, daptomycin, ceftaroline and mupirocin against MRSA isolates. Results: All the 60 MRSA isolates tested were sensitive to vancomycin, tigecycline, linezolid, daptomycin, ceftaroline and mupirocin (100%) and none of the MRSA isolates show resistance. Conclusions: Results of present study indicates that these agents may be used alongside vancomycin in management of infection caused by MRSA.
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Background: Antibiotic resistance is one of the greatest threats in human health. Extended spectrum ? lactamases mediated resistance is prevalent worldwide, Klebsiella pneumoniae and Escherichia coli leap out as this significant ESBL producers conferring resistance to the expanded spectrum cephalosporins. Colistin is being administered as last line therapy for patients that have failed to respond to other available antibiotics that are active against Gram-negative bacteria. Methods: The present study was conducted at school of medical education Kottayam, Kerala from January 2023 to November 2023.During the period of study 150 isolates of K. pneumoniae and 136 isolates of E. coli were collected from various diagnostic microbiology laboratories in Kerala. The colistin susceptibility pattern of ESBL producing isolates was detected by broth disc elution method recommended by CLSI. Results: In this study prevalence of multi-drug resistant is 6% and 9.6% and Extensively-drug resistant is 62% and 63.9% for K. pneumoniae and E. coli respectively. ESBL production was detected as 72% in K. pneumoniae and 79% in E. coli. The colistin susceptibility pattern of ESBL producing K. pneumoniae and E. coli was detected as 76.9% and 87.9% respectively Conclusions: Our result demonstrated that the recent use of colistin as last resort treatment for extensively drug resistant gram-negative bacilli, it is essential to know the prevalence of susceptibility pattern to this antibiotic.
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Background: Klebsiella pneumoniae are Gram-negative opportunistic pathogen, belonging to the family Enterobacteriaceae that can cause severe nosocomial infections particularly in immuno-compromised individuals. They exhibit co-resistance to multiple antibiotics which emphasize the need for non-antibiotic therapies. The goal of the presented study was to investigate the antimicrobial ability of probiotic Lactobacilli on clinical isolates of K. pneumoniae. Methods: In this cross-sectional study, antimicrobial activities of probiotic L. acidophilus and L. rhamnosus on K. pneumoniae were evaluated by Agar overlay interference technique. Clear zone around Lactobacilli were taken as positive inhibition. Antibiotic susceptibility profiles of K. pneumoniae were determined by Kirby-Bauer disk diffusion method, analyzed using interpretive standards of CLSI M100-S33 and categorized into MDR, XDR and Non MDR groups. Statistical analysis was done using descriptive statistics such as mean and standard error and inferential statistics such as ANOVA single factor. Results: K. pneumoniae exhibited positive inhibition with both the probiotic strain. On comparing the zone of inhibition of L. acidophilus and L. rhamnosus (both treated-pH adjusted and untreated), L. acidophilus had greater zone of inhibition against K. pneumoniae but concluded that statistically the values are insignificant (p>0.05). Based on antibiotic susceptibility pattern of K. pneumoniae, 63% of isolates were XDR, 3% were MDR and 34% were Non MDR Conclusions: It can be concluded that L. acidophilus and L. rhamnosus had significant inhibitory effect against K. pneumoniae in vitro and should be further studied for their human health benefit.
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Background: The present investigation aims to evaluate both the intensity and occurrence of hepatic impairment in patients afflicted with gallstone disease, examining the involvement of bacteria in the progression of these alterations. Methods: This prospective observational investigation was carried out on 189 patients scheduled for open or laparoscopic cholecystectomy at IGIMS in Patna, Bihar, India. In all the patients, laboratory and radiological investigations were performed. A healthy section of the liver border near the gallbladder fossa was chosen and grasped with non-traumatic forceps. Approximately 1 cm of the liver edge was excised using scissors and forwarded for histopathological analysis. Results: An examination of 189 liver biopsy specimens revealed that 87 (46%) patients showed no abnormalities, while 102 patients (54%) exhibited one or more changes. Upon analysing the liver biopsy samples from the control cohort (41 patients) during autopsy, 37% of the cases were identified to display hepatic lipidosis, while 48% of the cases showed lymphocytic invasion. Importantly, no cases of acute inflammatory changes were detected in the control cohort. Microbiological analysis was conducted on 96 patients, of which 33 (34%) showed positive cultures, with one or more microorganisms isolated from either the biliary tract or liver. Among these, 74% (24 cases) originated from the bile or gallbladder, while 26% (9 cases) were isolated from the liver. Conclusions: Gallstone disease induces significant liver histological changes, notably more prevalent in patients with prolonged symptoms. The present study clearly identifies this and underscores the importance of timely diagnosis and intervention for the effective management of this disease.
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Background: In accordance with section 3(1) of the 1875 Indian majority act, any individual residing in India must reach the majority age when they reach the age of 18 and not before. Third molar formation begins approximately the age of 18. This study aims to distinguish the third molar Demirjian stage(s) indicate that the individual is under the age of 18, and which do not, we will be able to determine the person's age. Methods: In this research, 202 patients' OPG radiographs aged 14-25 years were obtained. Their radiographs revealed 742 third molars in total. Third molar development was examined using Demirjian's eight-stage method, and average age was then calculated for each step of third molar growth. Stages under the age of eighteen and stages over the age of eighteen were analyzed. Results: Data revealed that a person was in stage C most likely under the age of 18 (minor) and at stage H, a person was most likely over the age of 18 (major). Stages A and B were not evident in the age range studied. The age associated with stage C was less than 18 years, while the age associated with stage H was greater than 18 years. Conclusions: Assessing third molar growth stages is a reliable non-invasive method for estimating an individual's age. Stage H indicates a likely age over 18 with completed root development, while stage C suggests an age under 18 with ongoing root development, making it a quick and useful approach.
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Background: Limited evidence is available on the psychological distress among patients hospitalized with COVID -19. We assessed the incidence of psychological distress, posttraumatic symptoms and substance use among patients hospitalized with COVID-19; and perceived stress, coping, and social support experienced by distressed and non-distressed patients and the predictors of psychological distress. Methods: Ours was a hospital-based cross-sectional study, conducted in a Union Territory of India. Patients were assessed (August – September, 2020) at the time of admission (within two days) with standardized instruments (N=250). Results: More than 19 percent of respondents had experienced significant psychological distress (probable cases) and nearly 9% reported post-traumatic stress symptoms. The cases and non-cases differ in terms of active coping (5.51±0.87 versus 5.06±1.06; t=3.10, p<0.01), emotional support (5.21±0.87 versus 4.86±0.79; t=2.57, p<0.01), behavioural disengagement (5.18±0.92 versus 4.55±1.15; t=3.56, p<0.001), venting (5.42±0.96 versus 4.80±1.24; t=3.30, p<0.01), acceptance (5.75±1.24 versus 5.29±1.50; t=2.23, p<0.05), religion (5.43±1.41 versus 6.06±1.46; t=-2.76, p<0.01) and self-blame (5.65±1.00 versus 4.82±1.39; t=3.95, p<0.001). Symptoms of post-traumatic stress (OR: 2.058; 95% CI: 1.49-2.84) was the only significant predictor of the psychological distress. Conclusions: Nearly one in five hospitalized patients with COVID-19 experience psychological distress. Screening and treatment for trauma and psychological distress should be an integral component of care for patients with COVID-19.
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The field experiment was conducted at Agronomy Research FaTArm, Narendra Deva University of Agriculture and Technology, Narendra Nagar (Kumarganj) Faizabad (U.P.), during Rabi season of 2014-2015. The yield components like number of spikes m-2, spike length (cm), number of grain spike-1, grain weight spike-1(g), grain yield (kg ha-1), straw yield (q ha-1) and nitrogen contain in grain (%), nitrogen contain in straw (%), nitrogen uptake in grain (kg ha-1), nitrogen uptake in straw, protein content in grain (%) were maximum under 160 kg N ha-1 and among the varieties over PBW-373, NW-1014 being at par with HD-2327. The main aim of trial conducted that to know the different varietal parameters of wheat crop.
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The poisonous and invasive weed Parthenium hysterophorus L., also referred to as "famine weed" or "congress grass," is highly dangerous for human health, agriculture, and biodiversity. This plant is well known for its aggressive growth and allelopathic qualities, which prevent natural vegetation and good crops from growing. An overview of the benefits and treatment of Parthenium hysterophorus is given in this abstract. Many techniques, including mechanical removal, chemical herbicides, biological control agents, and cultural practices, are used to combat this weed. To successfully control its spread, integrated techniques are frequently advised. Parthenium hysterophorus has drawbacks, yet it also has some positive qualities. It has therapeutic qualities, and research indicates that it may be used in phytoremediation and the synthesis of biofuel. The main goal is to draw attention to how critical it is to manage Parthenium hysterophorus properly while investigating its possible benefits, underscoring the necessity of long-term, all-encompassing solutions to deal with this environmental threat.
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A field experiment was carried out at Soil Conservation and Water Management Farm of C S Azad University of Agriculture and Technology, Kanpur during Zaid seasons i.e. 2022 and 2023 to assess the effect of irrigation scheduling and integrated nutrient management on blackgram.The experiment consisted of three irrigation schedulesviz.I1:0.4 IW/CPE, I2:0.6 IW/CPE, I3:0.8 IW/CPE, along with five integrated nutrient management options viz.F1: 100% RDF, F2:125% RDF.F3: 75% RDF + 2.5 ton FYM/ha,F4: 50 % RDF + 5 ton FYM/ha.F5: 50% RDF + 2.5 ton FYM/ha + 1 tonvermi-compost. The experiment was conducted in Split Plot Design replicated thrice irrigation scheduling systems in main plots and integrated nutrient management in sub plots. The result clearly revealed that significantly higher growth attributes viz plant height (35.25 cm and 37.56 cm), number of branches plant-1 (8.87 and 9.21), number of plant leaves (19.96 and 20.29) at harvest and yield attributes viz number of pod per plant (27.80 and 30.10) no of seed per pod (6.62 and 6.91) and also higher seed yield (9.30 q ha-1 and 9.90 qha-1 ), stover yield(23.21 q ha-1 and 24.03 q ha-1) were recorded with I3: 0.8 IW/CPE compared to I1: 0.4 IW/CPE and I2: 0.6 IW/CPE. Among the integrated nutrient management significantly higher growth attributes viz plant height (36.12 cm and 38.07 cm), number of branches plant-1 (9.01 and 9.32), number of plant leaves (20.05 and 20.45) at harvest and yield attributes viz number of pod per plant (28.44 and 30.17) no of seed per pod (7.05 and 7.37) and also higher grain yield (9.73 q ha-1 and 10.27 qha-1 ), stover yield(23.55 q ha-1 and 24.76 q ha-1) were recorded with F5:50% RDF + 2.5 ton FYM/ha + 1 ton vermi-compost as compared to other integrated nutrient management protocol.
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The present investigation entitled Study the impact of abiotic factors on the population fluctuation of major insect pest of field pea was conducted at the Experiment field of Department of Plant breeding, seed Breeding farm, JNKVV Jabalpur (MP), Madhya Pradesh during the Rabi season 2020-21. Positive correlation of Acryothosiphon pissum, pod borer, and leafhopper with Maximum Temperature (0.581, 0.581, 0.582) and Acrythosiphon pissum with morning vapour pressure (0.453) may be given due weightage in formulating forewarning modules in the pest. Similarly positive correlation was found between Relative humidity and aphid (r = -0.304) and was found significant. Max temperature showed significant negative correlation (r=-0.581) with aphid, Pod borer and leafhopper’s population where minimum temperature and rainfall showed negative correlation (r=-0.453 and r= - 0.153) with aphid population. Whereas min temperature showed positive non-significant correlation (r= 0.413). Max temperature showed significant negative correlation (r = -0.581) with pod borer population. Morning vapour pressure shows significant negative correlation (r=-0.453) with aphid population.
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India is the second largest producer of fruits in the world with different fruit growing zones viz., temperate, arid and semi-arid, subtropical, and tropical zones. In this present era of climate change, fruit growers are facing environment-related problems such as sudden changes in temperature, irregular and heavy rainfall, and soil-related problems like compaction, salinity, alkalinity, and acidity. In addition to this, pest and disease incidence also play a major role in limiting fruit production. Objectives of rootstock breeding includes resistance or tolerance to biotic stress, adaptability to soil and environmental conditions, dwarfism, precocity in bearing, high yield and good fruit quality. The purpose of rootstock breeding varies with crops and geographical locations. Developing rootstocks resistant or tolerant to biotic stresses in apple (fire blight and woolly apple aphid), citrus (root rot, nematodes and viral diseases), grape (Phylloxera spp. and nematode) and mango (mango fruit fly and stone weevil) for specific tree characters (dwarfing, canopy management) and horticultural traits (yield and quality) are the important aspects in rootstock breeding. The reported rootstocks which are impactful in fruit cultivation like apple (MM-111), grape (Dogridge, 99-R, 110-R and 1103-P), and mango (Turpentine, Deorakhio and Olour). The use of rootstocks which are tolerant or adaptable to adverse climatic situations and biotic stress can be an alternative option for scientists and fruit growers to face the challenges encountered by the fruit industry.
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Aims: This study aims to scrutinize the intricacies of nutrient management to optimize the cultivation of black gram (Vigna mungo L.) during the Rabi season of 2022-2023 in Coimbatore. The primary objectives include evaluating the efficacy of various treatments, such as recommended doses of inorganic fertilizer (RDF), rhizobium, and Phosphobacteria microbial inoculants as soil applicants, as well as TNAU Pulse Wonder, nano urea, and DAP as foliar sprays.Study Design: A meticulous Randomized Block Design (RBD) with three replications was employed to explore diverse treatments. This design allowed for a systematic investigation into the impact of different nutrient management strategies on the growth and yield of black grams.Place and Duration of Study: The study was conducted in Coimbatore, and the Rabi season of 2022-2023 was chosen for its duration. The experimental setup was established at the research farm under the auspices of the Karunya Institute of Technology and Sciences.Methodology: A total of ten treatments were tested, including various combinations of RDF (25:50:25), rhizobial culture, phosphobacteria, TNAU Pulse Wonder, nano urea, and DAP. Plant growth metrics, such as plant height and leaf count, were measured at 60 days after sowing (DAS). Yield attributes, including pod count, seeds per pod, and test weight, were also evaluated. Economic scrutiny included the calculation of the cost of cultivation, gross return, net income, and benefit-cost ratio.Results: Treatment T7, consisting of 75% RDF, rhizobial culture, phosphobacteria, and 1% TNAU Pulse Wonder, demonstrated substantial efficacy in enhancing plant growth metrics. At 60 DAS, this treatment exhibited an appreciable increase in plant height (39.89 cm) and leaf count (15.33). Moreover, T7 positively impacted crucial yield attributes, with elevated pod count (24.33), seeds per pod (9.33), and test weight (4.98 g). Economic scrutiny identified T7 as the epitome of economic viability, featuring a cost of cultivation at 30,240 INR, gross return of 125,587.80 INR, net income of 95,347.80 INR, and a commendable benefit-cost ratio of 4.15.Conclusion: These findings underscore the profound significance of strategic nutrient management paradigms for fostering sustainable and economically robust black gram cultivation. The identified treatment T7 stands out as a promising approach to optimize yields and economic returns in black gram cultivation, offering valuable insights for future agricultural practices.
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Bamboo is a versatile group of fastest growing plant which is capable of providing ecological, economical, environmental and livelihood security to the people. The study investigates uses, contribution, scope of the green gold plant bamboo. The review of this study showed that bamboo has evolved into a highly valuable and superior plant which serves for food, fodder and many more also bamboo-based products have the potential to replace wood, plastics in a variety of industrial uses without harming the nature by maintaining sustainability. So in this review paper comprehensive overview of the recent literatures about multidimensional scope of bamboo in form of its greatest potential is being discussed.
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This research focuses on the functional characterization of 19 rhizobia strains isolated from Southern Rajasthan's Udaipur and Dungarpur districts, with an emphasis on their multiple Plant Growth Promoting (PGP) activities. Through a series of tests encompassing Indole-3-Acetic Acid (IAA) production, siderophore production, phosphate solubilization, ammonia production, and hydrogen cyanide (HCN) production, this study elucidates the diverse PGP potential of these rhizobia strains. The results showcase variations in IAA production, highlighting their ability to enhance root development and overall plant growth, while also revealing strains capable of siderophore production, indicating potential iron uptake facilitation. Furthermore, some strains exhibit phosphate solubilization, ammonia production, and HCN production capabilities, signifying their potential to improve nutrient availability and protect plants from pathogens. These findings underscore the promise of harnessing the PGP activities of these rhizobia strains for sustainable agricultural practices in Southern Rajasthan and similar agroecological regions, with implications for enhanced crop yields and soil health.
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Among the various treatments evaluated for their bio-rational effect against mustard aphid on Indian mustard during year- 2021-22 at C. S. Azad University of Agriculture & Technology Kanpur Uttar Pradesh, the descending order are the followed treatments are NSKE @10% > NSKE @5% > Cow Urine @ 10% > Verticillium lecanii @ 1.5kg/ha. > Lantana leaf extract @ 10 % > Castor leaf extract @ 10% > Lantana leaf extract @ 5 % > Castor leaf extract @ 5% > Cow Urine @ 5%. India, the spray of NSKE 10% @ 60 lit/ha followed by NSKE 5 % @ 30 lit/ha was proved to be the best treatments with pooled mean aphid population of 5.42, 5.10, 4.96, 4.85, 5.39, 5.26, 5.42, 5.23, 5.13, and 7.29 aphid/pant in the control after 1, 3, 5 and 7 days of treatment, respectively. The treatment NSKE 10 % was proved best and significantly superior over all treatments with highest reduction of Infestation of Lipaphis erysimi kalt. in both the years.
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A field experiment was conducted during 2019 and 2020 to evaluate the effect of tillage and residue management on weed dynamics and productivity of direct seeded rice with four tillage systems; Conventional tillage in rice and wheat, Zero tillage in rice and wheat and two rotational tillage sequences that alternated between Conventional tillage and Zero tillage whereas four residue management practices; residue applied in both season, residue applied in kharif season only, residue applied in rabi season only and without residue in both season. The experiment was carried out at research farm of Birsa Agricultural University, Ranchi, Jharkhand. Results revealed that in direct seeded rice having highest grain yield (10%), straw yield (8%) and yield attributes (10-15%) as well as lesser weed density and weed dry matter found under Conventional tillage during both the seasons of experiment but performance of zero tillage was slightly better (3-4%) in second year as compared to all treatments. Whereas surface retention of residue @5 tonne/ha was significantly more effective in controlling different category of weeds, it decreased up to 60-75% weed population, resulting increment in grain yield up to 19% and 23% during first and second year, respectively, as compared to plot receiving no residue.
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The current investigation on the repercussions of drought stress on the growth parameters of the Moth bean (Vigna aconitifolia) has been carried out in a semi-field condition. Two sets of local moth bean cultivars (RMO-40: fifteen in each) were prepared, and one was subjected to terminal drought stress. The rest was maintained with proper watering as a control set. The treated plants were thoroughly evaluated based on leaf length, root length, and relative leaf water content in comparison with the control ones. The findings of this study reveal a significant impact of drought stress on moth bean's growth and physiological performance. Under drought conditions, treated plants exhibited considerable reductions in leaf length and root length compared to their well-watered counterparts. Additionally, the relative leaf water content declined under drought stress, indicating decreased water uptake and retention within the plants under stress. These outcomes underscore the vulnerability of moth bean to drought stress, emphasizing the urgency of developing efficient water management strategies and drought-resistant varieties to safeguard food security in regions where this legume serves as a staple crop. This research highlights the importance of understanding the adverse effects of drought stress on moth bean's growth parameters for sustainable agriculture and food production.
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Use of biological agents and fungicides like- T. viride at 2.5%, T. harzianum @ 2.5% and Pseudomonas fluorescens @ 2%, neem leaf extract at 10%, garlic extract at 10%, and carbendazim at 0.1% as a fungicide in powdery mildew disease for give the better results compare to control. A germplasms lines of mungbean were tested for resistance to Macrophomina phaseolina along with JL-781 as a susceptible check in sick plots these test lines. Among the 2 were moderate resistant, 1 germplasm was moderate susceptible, 1 germplasm was susceptible and JL-781 to highly susceptible. A visual scoring index (VSI) was used to evaluate the signs and symptoms of MYMV infection. Compared to the primed plants, which only had 14% of the same symptoms, more than 70% of the unprimed plants had symptoms that were considered serious or deadly. Whitefly control with insecticides has been deemed helpful for managing yellow mosaic virus. The environment and human health were also negatively impacted by the over usage of chemicals. Preventive and therapeutic measures using pesticides effectively is crucial for preventing soil-dwelling and seed-borne infections across all IDM strategies. All of the fungicides outperformed traditional fungicides in terms of performance.