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مقالة ي صينى | WPRIM | ID: wpr-621909

الملخص

A new chitosan derivative is prepared using chitosan.Ethyl chlorocarbonate was first introduced to the hydroxyl group of phthaloylchitosan through a nucleophilic reaction.Hydrazine was then added to recover the amino groups of chitosan and promote cross-linking.The structure of this new chitosan derivative was characterized by Fourier transform infrared(FT-IR)and proton nuclear magnetic resonance(1H NMR)spectroscopy,and its physical properties were determined by X-ray diffraction(XRD),differential scanning calorimetry(DSC),and thermogravimetric analysis(TGA).The thermal and chemical stabilities of the new derivative were improved compared with those of native chitosan.Assay of Escherichia coli adhesion on a film based on this chitosan derivative showed good adsorption and biofilm formation.

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