Porokeratosis ptychotropica

Abstract Porokeratosis is a skin disorder clinically characterized by annular plaques with keratotic borders resembling the Great Wall of China and histopathologically by cornoid lamellae. The disease has several clinical variants. Porokeratosis ptychotropica, which has recently become part of these variants, is quite rare and little known. The entity is characterized by verrucous plaques – which may resemble a psoriasis plaque – that affect the regions of the buttocks, most commonly the gluteal cleft, with or without extremity involvement. Itching is often present. We report a rare case of porokeratosis ptychotropica and highlight its unusual manifestation (single plaque), the first case reported in the Brazilian literature.

Plasmoacanthoma

Abstract Plasmoacanthoma is an extremely rare verrucous tumor located on periorificial regions characterized by dense dermal plasmacytic infiltrates. Some authors classify it as a form of reactive plasma cell proliferation which represents a heterogeneous spectrum of mucocutaneous disorders. These plasma cell proliferations have been considered to be a benign immunologic inflammatory reaction to known or unknown stimuli. However, the etiology of plasmoacanthoma remains highly speculative. We report the case of a 40-year-old woman who presented with a lobulated warty lesion affecting the lower lip. Biopsy from the lesion was compatible with plasmoacanthoma, which remains an underreported disease in the dermatology literature.

Lupus tumidus: a report of two cases

Abstract Lupus tumidus is considered a rare subtype of chronic cutaneous lupus erythematosus, characterized by erythema and bright urticarial erythematous-violaceous lesions that leave no scars after regression. Histopathology reveals perivascular and periannexal lymphohistiocytic infiltrates in the papillary and reticular dermis and interstitial mucin deposition. Treatment is based on photoprotection, topical corticosteroids and antimalarials. We report two cases of lupus tumidus, which deserve attention for their low frequency in the literature, in addition to their relevance as a differential diagnosis among dermatologic disorders.

Cutaneous metastasis from gastrointestinal adenocarcinoma of unknown primary origin

AbstractCutaneous metastasis is a rare manifestation of visceral malignancies that indicates primarily advanced disease. Due to its low incidence and similarity to other cutaneous lesions, it is not uncommon to have a delayed diagnosis and a shortened prognosis. We describe the case of a patient who presented with a cutaneous nodule in the sternal region as a first sign of malignancy.

Type 2 segmental glomangioma - Case report

Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was progression of lesions throughout the body. Multiple glomangiomas are asymptomatic and more common in childhood. They can be confused with other vascular malformations. Histopathological diagnosis is essential. The case shows a type 2 segmental manifestation that can be explained by genetic mutation leading to the loss of heterozygosity. As the child grows, the lesions may disseminate due to mutation in distant parts of the skin. Literature shows few reports. The treatment is conservative.

Tumor of follicular infundibulum with unique features

Tumor of the follicular infundibulum is a rare benign cutaneous adnexal neoplasm with variable clinical presentation. In most cases the diagnosis is made with the help of histopathology, due to lack of a characteristic clinical presentation. The most common form is a solitary lesion, but it can be multiple or eruptive, then called infundibulomatose. This case report illustrates a patient with multiple lesions of tumor of the follicular infundibulum with bizarre aspect and atypical location.

Musculoskeletal and cutaneous sarcoidosis: exuberant case report

Sarcoidosis is a multisystem granulomatous disease of unknown cause. The osteoarticular involvement in sarcoidosis is rare and is often associated with cutaneous and long-standing chronic multisystem disease. More common in black women, osseous sarcoidosis is difficult to diagnose, with an incidence of 3 to 13%. The most characteristic radiological clinical picture evidences rounded, well-defined cysts, with no periosteal reaction and without peripheral sclerosis. The small bones of hands and feet are the most frequently involved sites. This report aims to demonstrate a rare case of osteoarticular sarcoidosis with characteristic clinical presentation, and highlight the importance of detecting osteoarticular involvement in this pathology.

Primary cutaneous Ewing sarcoma - Case report

Ewing sarcoma is a primitive neuroectodermal tumor rarely occurs in the skin and sobcutaneous tissues. Generally Ewing's sarcoma is a primary bone tumor, but when present in soft tissues it characterizes an extremely uncommon clinical picture. It usually involves the deep subcutaneous tissue or muscles, and more rarely occurs like a primary skin cancer. Most patients are white, women, and in the second decade of life. The clinical features are a superficial mass, in average measuring 2-3 cm, of soft consistency, freely mobile and sometimes painful. The more affected locations are upper and lower extremities, trunk, head, neck or multiple lesions. The presence of metastases is very rare.

Estudo clínico para avaliação do filtro solar Filtrum FPS 50 Alta Proteção: avaliação cosmética / Clinical study of sunscreen SPF 50 Filtrum Alta Proteção: cosmetics assessment

Este estudo clínico foi realizado com Filtrum FPS 50 Alta Proteção em voluntários saudáveis. Realizou-se avaliação sensorial...

Neuroma encapsulado em paliçada - simulando carcinoma basocelular: relato de caso / Case report: Palisaded encapsulated neuroma simulating a Basal Cell Carcinoma

Os neuromas encapsulados em paliçada são tumores neurais solitários da pele caracterizados pela presença de feixes compactos e paralelos de fascículos de células de Schwann. Apresenta-se um caso desse tumor, confirmado por exame anatomopatológico, em paciente do sexo feminino, de 55 anos, que relatou mácula hipocrômica de crescimento que evoluiu para pápula de superfície lisa e em domo, com telangiectasias, simulando carcinoma basocelular. Ter conhecimento dessa entidade é importante para a realização de diagnósticos diferenciais com outras lesões, em especial com o CBC, tumores de apêndice cutâneo, nevos e cistos epidérmicos.

Palisaded encapsulated neuromas are solitary neural skin tumors characterized by the presence of compact and parallel bundles of Schwann cell fascicles. The present article reports a case of this type of tumor, which was confirmed by anatomic pathological examination of a 55-year-old female patient who reported hypochromic macula growth, which had evolved into a smooth domed superficial papule with telangiectasias, simulating a basal cell carcinoma. Having knowledge of this entity is crucial in order to carry out differential diagnoses-comparing it to other lesions-especially basal cell carcinomas, skin appendage tumors, nevi, and epidermal cysts.

Dermatúnel: modelo de ambiente interativo de aprendizagem em dermatologia / Dermatúnel: a model of interactive learning environment in dermatology

O Ambiente Interativo de Aprendizagem (AIA) é um modelo educacional que integra recursos de computação gráfica 3D e contextualização, com objetivo de transmitir um conjunto de conhecimentos (ilhas de conhecimento), de forma precisa e ágil, para pessoas que não conhecem o assunto. Utiliza recursos de multimídia apoiados em ambientação contextualizada para motivar os participantes na retenção de conhecimento. Na primeira versão, foram abordados oito assuntos relevantes de dermatologia. O modelo foi implementado no 62º Congresso Brasileiro de Dermatologia e denominado Dermatúnel. Participaram das visitas 3295 pessoas, num período de quatro dias. Os resultados demonstraram alta satisfação dos participantes. Possui grande potencial como ferramenta educacional para formação médica e orientação do público geral para fins de prevenção de doenças.

The Interactive Learning Environment (ILE) is an educational model that integrates features of 3D computer graphics and contextualization, in order to transmit a quantum of knowledge (islands of knowledge), in a precise and agile way, to people who do not know the subject. It is a model that uses multimedia resources supported by a contextualized environment to motivate the participants in the retention of knowledge. In this first release, eight relevant subjects in dermatology were addressed and implemented in the 62nd Brazilian Congress of Dermatology. The model was called Dermatúnel. In a period of four days, 3295 people visited it. The results showed that the participants were highly satisfied. The model has a great potential as an educational tool for medical training and guidance to the general public with the purpose of disease prevention.

Líquen escleroso e atrófico "versus" esclerodermia circunscrita: pertencem ou näo à mesma entidade clínica?: a propósito de um caso / Lichen sclerosus ans atrophicus versus circumscribed scleroderma: report of case

O líquem escleroso e atrófico (LEA) e a esclerodermia sao dermatoses que se assemelham clínica e histologicamente, dificultando muitas vezes um diagnóstico preciso em muitos casos. Foi a partir do atendimento a um paciente que apresentava lesoes clínicas de LEA e esclerodermia, ou seja, dessa dificuldade, que tentamos estudar as duas entidades, buscando na literatura cientistas que trouxeram técnicas novas com resoluçoes definitivas.

Neurofibromatose: revisäo da literatura / Neurofibromatosis: review of the literature

A neurofibromatose é doença de herança autossômica dominante, caracterizada pela presença de máculas hiperpigmentares, neurofibromas e tumores dos sistemas nervoso central e periférico. Segundo dados recentes da literatura, existem várias formas de neurobibromatose, porém as mais conhecidas säo a neurofibromatose tipo 1 (NF-1) e a neurofibromatose tipo 2 (NF-2). A NF-1 se caracteriza pela presença de múltiplas manchas "café com leite", nódulos de Lisch (hamartomas de íris), gliomas do nervo óptico e neurofibromas dérmicos. O gene responsável está localizado no braço longo do cromossomo 17. A NF-2 tem como principais características a presença de neuromas acústicos bilaterais e opacidade subcapsular posterior do cristalino. O gene responsável por esta patologia encontra-se no centro do braço longo do cromossomo 22. Embora muitos avanços tenham sido feitos até esta data quanto ao estudo dessa doença, devemos reconsiderar todos os dados disponíveis, as conclusöes e, principalmente, as novas pesquisas, visando obter melhor direcionamento do diagnóstico, prognóstico e tratamento da doença

Casuística do Ambulatório de Dermatologia da Faculdade de Medicina de Santo Amaro no período de 5 anos / Case study of \"Ambulatório de Dermatologia da Faculdade de Medicina de Santo Amaro\" during 5 years

De janeiro de 1987 a dezembro de 1991 foram atendidos 10.324 pacientes no Ambulatório de Dermatologia da Faculdade de Medicina de Santo Amaro (serviço do Prof. Dr. Luiz Carlos Cucé), dos quais registramos a doença dermatológica apresentada. A dermatoscopia de maior incidência correspondeu à escabiose, com 8,7 por cento, seguida de dermatoses raras, com 7,1 por cento, pitiríase versicolor, eczema atópico e tinhas, com 5,9 por cento cada. Os autores correlacionaram estas incidências com dados da literatura nacional e internacional. A análise desses resultados auxilia outros órgäos de saúde na prevençäo das doenças mais incidentes que dependem de educaçäo sanitária populacional.

Incidência das dermatoviroses no Centro de Saúde Escola da Faculdade de Medicina de Santo Amaro-SP / Incidence of dermatoviroses at the Health Service of the Santo Amaro School of Medicine - SP, Brazil

Os autores procuram enfatizar a importância da incidência das dermatoviroses dentre as dermatopatias já que säo pobres os dados médicos nacionais sobre esse grupo de pacientes. No intuito de enriquecer essas informaçöes, fazem comparaçöes com centros de outros países e com os poucos dados nacionais anteriores aos obtidos nesta notificaçäo. Dentre 14.561 diagnósticos obtidos, foi observada uma incidência de 6.4% de dermatoviroses, dado que sugere um aumento de incidência deste grupo de doenças

Efeitos dermatológicos em usuárias de contraceptivos hormonais orais (COS) / Dermatological effects in hormonal oral contraceptives users

Os autores discutem efeitos dermatológicos adversos, relacionados ao uso dos contraceptivos hormonais orais, tanto sobre as alteraçöes dermatológicas pré-existentes como naquelas desencadeadas pelo COS

Eritema nodoso / Erythema nodosum

Os autores revisam e chamam a atençäo aos aspectos clínicos, históricos, etiopatogênicos, imunopatológicos, diagnósticos diferenciais e tratamento de uma patologia dermatológica relativamente comum e que em muitas ocasiöes é confundida com outros diagnósticos