Research on the apoptosis in and pathology of tendinopathy / 中华创伤骨科杂志

Tendinopathy refers to a syndrome of pain, swelling, and impaired performance of tendon and paratenon that is caused by overuse of tendon and paratenon. In the past three decades, the incidence of tendinopathy increased obviously. Although extensive researches have been done, we still do not know much about its pathogenesis, pathology and therapy. In this paper, the authors review its pathological classification, its macroscopic, light microscopic and electron microscopic features, and the morphology of apoptotic cells under light microscopy. The paper also highlights the recent research on how stimulation leads to apoptosis and further to tendinosis.