الملخص
ABSTRACT Objective: To determine the practices of Family Physicians/General Practitioners in Kingston and St Andrew regarding the management of adult obesity and compare their management to the 2013 American College of Cardiology/American Heart Association/Task Force on Practice Guidelines and The Obesity Society (AHA/ACC/TOS) Guidelines for the Management of Overweight and Obesity in Adults. Methods: A cross-sectional study was done of Family Physicians/General Practitioners in the Kingston and St Andrew area. A Census approach was used with the aid of a self-administered questionnaire and practices compared to the American Guidelines for Obesity Management. Results: There were 117 respondents out of the 155 Family physicians/General practitioners. While most physicians were found to have medium to high level practice scores, 23% had low practice scores. Diagnosis of obesity using body mass index (BMI) was high (99%), but only 64% employed hormonal assays. Almost 36% did not refer patients with BMI > 40 kg/m2 for bariatric surgery. Conclusion: Assessed against existing guidelines, physicians were found generally to have medium to high practice levels regarding management of obesity, however, gaps remain to be closed.
RESUMEN Objetivo: Determinar las prácticas de los médicos de familia/médicos generales en Kingston y Saint Andrew en relación con el tratamiento de la obesidad en adultos y comparar su tratamiento con las Pautas para el Tratamiento del Sobrepeso y la Obesidad en Adultos del Colegio Americano de Cardiología/Sociedad Americana del Corazón/Grupo de Trabajo para las Guías Prácticas y la Sociedad de la Obesidad (AHA/ACC/TOS) de 2013. Métodos: Se realizó un estudio transversal de médicos de familia/ médicos generales en el área de Kingston y Saint Andrew. Se usó un enfoque de censo con la ayuda de un cuestionario autoadministrado y prácticas comparadas a las pautas americanas para el tratamiento de la obesidad. Resultados: Hubo 117 encuestados provenientes de los 155 médicos de familia/médicos generales. Si bien se halló que la mayor parte de los médicos tenían niveles de medio a alto en las puntuaciones de la práctica, el 23% tenía puntuaciones bajas de la práctica. El diagnóstico de la obesidad usando el índice de masa corporal (IMC) fue alto (99%), pero solamente el 64% empleó ensayos hormonales. Casi el 36% no remitió pacientes con IMC > 40 kg/m2 para cirugía bariátrica. Conclusión: Evaluados frente a las pautas existentes, los médicos generalmente mostraron niveles de práctica medios a altos con respecto al tratamiento de la obesidad. Sin embargo, quedan aún vacíos por llenar.
الموضوعات
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Young Adult , Physicians, Family , Practice Patterns, Physicians'/statistics & numerical data , General Practitioners , Obesity/therapy , Body Mass Index , Cross-Sectional Studies , Health Care Surveys , Jamaicaالملخص
Incontinentia pigmenti is a rare X-linked dominant condition characterized by cutaneous, neural, ocular and dental manifestations. The condition has mainly been reported in Caucasian females. The aim of this case report is to highlight the clinical presentation in Afro-Caribbean twin girls. The girls demonstrated abnormal hair distribution, pigmented limbs and torso, small conical or missing teeth with delayed dental eruption.
La incontinencia pigmentaria es una rara condición dominante ligada al cromosoma X, caracterizada por manifestaciones cutáneas, nerviosas, oculares y dentales. La condición ha sido reportada principalmente en mujeres caucásicas. El objetivo de este reporte de caso es resaltar su presentación clínica en gemelas afrocaribeñas. Las chicas mostraron una distribución anormal del cabello, extremidades y torso pigmentados, pequeños dientes cónicos o ausentes con retraso en el brote dental.
الموضوعات
Humans , Female , Infant , Incontinentia Pigmenti/diagnosis , Diseases in Twins/diagnosisالملخص
Recent biotechnological advances have permitted the manipulation of genetic sequences to treat several diseases in a process called gene therapy. However, the advance of gene therapy has opened the door to the possibility of using genetic manipulation (GM) to enhance athletic performance. In such ‘gene doping’, exogenous genetic sequences are inserted into a specific tissue, altering cellular gene activity or leading to the expression of a protein product. The exogenous genes most likely to be utilized for gene doping include erythropoietin (EPO), vascular endothelial growth factor (VEGF), insulin-like growth factor type 1 (IGF-1), myostatin antagonists, and endorphin. However, many other genes could also be used, such as those involved in glucose metabolic pathways. Because gene doping would be very difficult to detect, it is inherently very attractive for those involved in sports who are prepared to cheat. Moreover, the field of gene therapy is constantly and rapidly progressing, and this is likely to generate many new possibilities for gene doping. Thus, as part of the general fight against all forms of doping, it will be necessary to develop and continually improve means of detecting exogenous gene sequences (or their products) in athletes. Nevertheless, some bioethicists have argued for a liberal approach to gene doping.
الموضوعات
Humans , Athletic Performance , Doping in Sports/methods , Gene Transfer Techniques , Genetic Enhancement/methods , Bioethical Issues , Doping in Sports , Endorphins/genetics , Endorphins/pharmacology , Erythropoietin/genetics , Erythropoietin/pharmacology , Genetic Enhancement , Insulin-Like Growth Factor I/genetics , Insulin-Like Growth Factor I/pharmacology , Myostatin/genetics , Myostatin/pharmacology , Vascular Endothelial Growth Factor A/genetics , Vascular Endothelial Growth Factor A/pharmacologyالملخص
Cada año hay más de 3 millones de muertes de niños menores de 5 años por neumonía y alrededor del 80 por ciento de ellas ocurren en países en desarrollo.