Calcaneal Fractures: A Soft Tissue Emergency

Calcaneal fractures are quite often seen in patients with axial loading injury. In the tongue-type of calcaneusal fractures or tuberosity avulsion fractures, bone fragments are often superiorly and posteriorly displaced, because of the insertion of the Achilles tendon and pull of the gastroc-soleus complex. The Ddisplaced bone fragment compresses the soft tissues, leading tothat makes skin necrosis. To prevent further soft tissue injury, early recognition of the injury by the emergency physician and immediate orthopedic consultation is needed.

An Irreducible Hip Dislocation with Femoral Head Fracture

Urgent reduction is required in cases of traumatic hip dislocation to reduce the risk of avascular necrosis of the femoral head. However, in cases of femoral head fractures, the dislocated hip cannot be reduced easily, and in some cases, it can even be irreducible. This irreducibility may provoke further incidental iatrogenic fractures of the femoral neck. In an irreducible hip dislocation, without further attempting for closed reduction, an immediate open reduction is recommended. This can prevent iatrogenic femoral neck fracture or avascular necrosis of the femoral head, and save the natural hip joint.

Results of High-Flex Total Knee Arthroplasty: Minimum 3-Year Follow-Up Result / 대한정형외과학회잡지

PURPOSE: The purpose of this study was to evaluate the results of high-flexion total knee arthroplasty. MATERIALS AND METHODS: We evaluated 355 patients (372 cases) who underwent total knee arthroplasty using high-flexion implants from January 2005 to December 2011. The patients included 36 men and 336 women with a mean age of 70.6 (52-88 years) years. Average follow-up duration was 59 months (36-77 months) months. Three types of high flexion implants were used in this study. We performed preoperative assessment and last follow-up clinical evaluation was performed using range of motion (ROM), knee score and function score according to the knee society clinical rating system and complications. Radiologic evaluation was performed using plain radiographs to evaluate loosening or osteolysis. RESULTS: The mean ROM increased from 114.9° preoperatively to 127.0° at the final follow-up. The average knee score improved from 60.5 points preoperatively to 90.9 points at final follow-up and knee function score improved from 49.0 to 84.4 points. The clinical results were improved in each type of implants. A radiolucent line was detected in 2 cases in the Sigma rotating platform flexion group and patellar tendon rupture occurred in 1 case in the NexGex legacy posterior-stabilized-flex group. Infection occurred in 2 cases after 2 and 5 years postoperatively in the Scorpio non-restrictive geometry group and were treated with revision arthroplasty. No significant loosening was observed. CONCLUSION: This study obtained good results after total knee arthroplasty using high-flexion implants, and no loosening was observed. There were no differences in the type of implants in regard to the ROM and clinical variables.

Medial Patellofemoral Ligament Reconstruction for Recurrent Patellar Instability Using a Gracilis Autograft without Bone Tunnel

BACKGROUND: Several tendon graft and fixation methods have been introduced in medial patellofemoral ligament (MPFL) reconstruction for recurrent patellar dislocation. The purpose of this study was to evaluate the results of MPFL reconstruction using a gracilis autograft fixation without bone tunnel in patients with recurrent patellar instability. METHODS: Nine patients (four males and five females) diagnosed with recurrent patellar instability from July 2009 to January 2013 and had MPFL reconstruction using a gracilis autograft were included. The average age of the patients was 24.6 years (range, 13 to 48 years), and the average follow-up period was 19.3 months (range, 12 to 30 months). For every patient, femoral attachment was fixed using suture anchors securing the patella by suturing the periosteum and surrounding soft tissue. Clinical evaluation included the Kujala, Lysholm, and Tegner scores; in addition, patients were examined for any complication including recurrent dislocation. The congruence angle and patella alta were assessed radiologically before and after surgery. RESULTS: The Kujala score improved from an average of 42.7 ± 8.4 before surgery to 79.6 ± 13.6 (p = 0.008) at final follow-up; the Lysholm score improved from 45.8 ± 5.7 to 82.0 ± 10.5 (p = 0.008); and the Tegner score improved from 2.8 ± 0.8 to 5.6 ± 1.5 (p = 0.007). The Insall-Salvati ratio changed from 1.16 ± 0.1 (range, 0.94 to 1.35) before surgery to 1.14 ± 0.1 (range, 0.96 to 1.29; p = 0.233) at the final follow-up without significance. The congruence angle significantly improved from 26.5°± 10.6° (range, 12° to 43°) before surgery to -4.0°± 4.3° (range, -12° to 5°; p = 0.008) at final follow-up. Subluxation was observed in one patient and hemarthrosis occurred in another patient 2 years after surgery, but these patients were asymptomatic. CONCLUSIONS: We achieved good results with a patellar fixation technique in MPFL reconstruction using a gracilis autograft employing soft tissue suturing in patients with recurrent patellar dislocation.

The Result of Bone Grafting for Fibrous Dysplasia / 대한골관절종양학회지

PURPOSE: Fibrous dysplasia is related to the mutation of gene encoding the alpha-subunit of a signal-transducing G-protein and has variable clinical course. Operation can be performed to prevent functional disorder or structural deformity. After curettage, autologous bone graft were used to fill the defects after curettage. The aim of this study is to compare the result of autogenous cancellous bone grafting and allogenic bone grafting for fibrous dysplasia. MATERIALS AND METHODS: Among the patients who visit our hospital during the period of April, 1997 to October, 2013, we selected 34 patients who diagnosed fibrous dysplasia and visited our clinic over 1 year. There were 13 males and 21 females. Average age was 26.4 (range 2 to 57) years old. Autogenous bone graft (group I) in 5 cases, Non-autogenous bone graft (group II) in 30 cases. Iliac bone is used in all cases of autogenous bone graft. There were no significant difference in age, follow-up period, preoperational laboratory finding between two groups. Radiographic image was done to evaluate the recurrence of fibrous dysplasia or secondary degeneration. RESULTS: There were four cases in recurrence (group I: 1 case, group II: 3 cases, p=0.554). In all recurrent cases, reoperations were done using curettage and autogenous iliac bone graft. There was no re-recurrence after reoperation. One case of secondary aneurysmal bone cyst was confirmed (group II) and 1 cases of pathologic fractures had developed (group I: 0 case, group II: 1 cases, p=0.559). No malignant change occurred. CONCLUSION: There were no significant difference between autogenous bone graft group and non-autogenous bone graft group. Our result suggested that autogenous bone graft seems to be good method to treat fibrous dysplasia, in the case of small volume of tumor lesion or non-weight bearing portion.

A case of hippocampal sclerosis diagnosed as cortical dysplasia due to preoperative brain MRI finding / 소아과

Hippocampal sclerosis (HS) is one of the most common features of intractable temporal lobe epilepsy. Generally it can be identified through brain magnetic resonance imaging (MRI) with high degree of sensitivity and specificity. Typical brain MRI findings of HS are hippocampal atrophy with hyperintense signal confined to the lesion. On the other hand cortical dysplasia exhibits blurring of the gray-white matter junction and abnormal white matter signal intensity. We present a case where preoperative brain MRI strongly suggested the presence of diffuse cortical dysplasia in the left temporal lobe but postoperative pathology revealed the temporal lesion to be unremarkable except for hippocampal sclerosis.

Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen

Bisphenol A (BPA), a ubiquitous environmental contaminant, has been shown to cause developmental toxicity and carcinogenic effects. BPA may have physiological activity through estrogen receptor (ER) -alpha and -beta, which are expressed in the central nervous system. We previously found that exposure of BPA to immature mice resulted in behavioral alternation, suggesting that overexposure of BPA could be neurotoxic. In this study, we further investigated the molecular neurotoxic mechanisms of BPA. BPA increased vulnerability (decrease of cell viability and differentiation, and increase of apoptotic cell death) of undifferentiated PC12 cells and cortical neuronal cells isolated from gestation 18 day rat embryos in a concentration-dependent manner (more than 50 micrometer). The ER antagonists, ICI 182,780, and tamoxifen, did not block these effects. The cell vulnerability against BPA was not significantly different in the PC12 cells overexpressing ER-alpha and ER-beta compared with PC12 cells expressing vector alone. In addition, there was no difference observed between BPA and 17-beta estradiol, a well-known agonist of ER receptor in the induction of neurotoxic responses. Further study of the mechanism showed that BPA significantly activated extracellular signal-regulated kinase (ERK) but inhibited anti-apoptotic nuclear factor kappa B (NF-kappaB) activation. In addition, ERK-specific inhibitor, PD 98,059, reversed BPA-induced cell death and restored NF-kappaB activity. This study demonstrated that exposure to BPA can cause neuronal cell death which may eventually be related with behavioral alternation in vivo. However, this neurotoxic effect may not be directly mediated through an ER receptor, as an ERK/NF-kappaB pathway may be more closely involved in BPA-induced neuronal toxicity.

Spatiotemporal Analysis of Retinal Waveform using Independent Component Analysis in Normal and rd/rd Mouse / 의학물리

It is expected that synaptic construction and electrical characteristics in degenerate retina might be different from those in normal retina. Therefore, we analyzed the retinal waveform recorded with multielectrode array in normal and degenerate retina using principal component analysis (PCA) and independent component analysis (ICA) and compared the results. PCA is a well established method for retinal waveform while ICA has not tried for retinal waveform analysis. We programmed ICA toolbox for spatiotemporal analysis of retinal waveform. In normal mouse, the MEA spatial map shows a single hot spot perfectly matched with PCA-derived ON or OFF ganglion cell response. However in rd/rd mouse, the MEA spatial map shows numerous hot and cold spots whose underlying interactions and mechanisms need further investigation for better understanding.

Prognostic Factors Affecting the Results of the Surgery for Cervical Myelopathy / 대한정형외과학회잡지

PURPOSE: This study was performed to investigate and define the factors affecting the results of surgery for a cervical myelopathy. MATERIALS AND METHODS: Seventy-eight cervical myelopathy cases, who underwent surgery from Jan. 1991 to Sep. 2001, were retrospectively reviewed. The patients were composed of developmental stenosis in 9, spondylosis in 21, OPLL in 12, HIVD in 34 and trauma in 2 cases. The causes of the disease, age, onset, pre-op JOA score, pre-op and post-op spinal canal diameter, Pavlov ratio and cord diameter and signal changes of cord on MRI were examined. The mean follow-up period was two years. The clinical results were evaluated according to the JOA score. Statistical analysis was made using the Pearson correlation coefficient and the Kruskal-Wallis method. RESULTS: The mean pre-op and post-op JOA score were 11.2 and 14.8 respectively. The mean recovery rate was 68.0%. The preoperative JOA score showed a positive correlation with recovery rate, and age, sagittal diameter and transverse area of the cord on MRI correlated negatively with the recovery rate. The result was poorer the higher the level involved. Patients with signal changes in the cord on MRI had a poor outcome after surgery. CONCLUSION: The prognostic factors affecting the results of the surgery for cervical myelopathy were age, pre-op JOA score, disease level, and sagittal diameter, transverse area and the signal changes in the cord on MRI.

Mediastinal Parathyroid Cyst

The mediastinal parathyroid cyst is a very rare cause of space occupying lesions in the mediastinum.We report a case of a non-functioning mediastinal parathyroid cyst that occurred ina 42 year-old male. He suffered from foreign body sensation of the throat whenever he wasin the supine position. A chest computed tomography showed a round cyst with a narrowbase attached to trachea. It was white and tan, thin-walled semi-transparent cyst containingyellow and tan serous fluid. Microscopically it was characterized by a thin fibrous wall linedwith a single or double layer of uniform cells with clear cytoplasm and small nuclei. The liningcells were immunopositive for chromogranin A.

Rounded Atelectasis: A Brief Case Report

Rounded atelectasis is a focal, pleural-based lesion that is the result of pleural and subpleural scarring and atelectasis of the adjacent lung tissue. We experienced a case of asbestosassociated rounded atelectasis that had developed in a 50-year-old male. When examined with routine chest radiography, the patient was shown to have an asymptomatic chest mass.Computed tomography showed a pleural-based mass with a curvilinear shape about 4.2 cmin greatest diameter in the medial basal segment of the right lower lobe. To exclude the possibilityof malignancy the mass was excised by video-assisted thoracotomy. The mass wasround and firm, and was gray and yellow in color. Microscopically, marked pleural fibrosisextended into the underlying lung parenchyme and then resulted in atelectasis. There areferruginous bodies in dense fibrous pleura.

Surgical Treatment of the Acute Acromioclavicular Joint Dislocation Using a Wolter Plate / 대한정형외과학회잡지

PURPOSE: To introduce the surgical technique of acute acromioclavicular joint dislocation using a Wolter plate and to evaluate its efficacy after surgical treatment. MATERIALS AND METHODS: Twenty-six patients who underwent surgical treatment of the acute acromioclavicular joint dislocation using a Wolter plate and who were followed up minimally for one year were reviewed. We analyzed the clinical results of pain, function, range of motion and radiologic reduction state of the acromioclavicular joint. RESULTS: All cases showed satisfactory results. By clinical evaluation, twelve cases (46%) were excellent and fourteen cases (54%) were good. By radiologic evaluation, twenty cases (77%) were excellent and six cases (23%) were good. By postoperative X-ray, vertical displacement of the clavicle was restored in all cases. No complications such as infection, loosening of screws, plate failure or redislocation after removal of the plate occurred. CONCLUSION: Acromioclavicular joint reconstruction using a Wolter plate is believed to be a useful method, which minimizes injury of the joint articular surface and provides enough stability for postoperative rehabilitation.

A Clinical Study of Soft Tissue Changes of the Midface after Mandibular Setback Surgery

Clinical Study of Jaw Cysts

A Comparative Study of Arrhythmogenic Doses of Epinephrine during Sevoflurane or Halothane Anesthesia in the Dogs / 대한마취과학회지

BACKGROUND: Epinephrine used in surgery to provide hemostasis may elicit ventricular arrhythmias. A desirable anesthetic would not sensitize the myocardium to exogenously administered epinephrine. So the effect of sevoflurane, which was introduced to clinical anesthesia recently, on cardiac arrhythmias induced by the infusion of epinephrine was compared with those of halothane which was already known to epinephrine-induced arrhythmia in the 14 mongrel dogs. METHODS: The authors compared the arrhythmogenicity (three or more premature ventricular contractions, PVCs)of intravenously administered epinephrine in 14 mongrel dogs who were randomly assigned to receive sevoflurane (1.7 vol%) or halothane (0.75 vol%) anesthesia equipotently. The arrhythmogenic doses of epinephrine determined in this comparative study were expressed by both infusion rates of epinephrine during sevoflurane and halothane anesthesia. RESULTS: The mean values of the arrythmogenic infusion rates of epinephrine were 27.1 7.6 g/kg for sevoflurane and 2.7 0.8 g/kg for halothane. CONCLUSIONS: We concluded that the arrythmogenic doses of epinephrine during sevoflurane were significantly higher than those during halothane anesthesia.

Clinical Study for Monitored Anesthesia Undergoing Ophthalmic Surgery / 대한구급학회지

Intoduction: The phrase "Monitored Anesthesia Care" refers to instances in which an anesthesiologist has been called upon to provide specific anesthesia services to a particular patient understanding a planned procedure, in connection with which a patient receives local anesthesia. Monitored anesthesia care is being increasingly used in the 1990s for a wide variety of diagnostic and therapeutic procedure. The primary objective in providing monitored anesthesia care is to ensure patient comfort and safety. METHOD: We classified patients in three groups by premedication and oxygen administration, no premedication and no oxygen administration (group A), premedication and oxygen administration (group B), premedication and no oxygen administration (group C), measured vital signs and SpO2 (peripheral oxygen saturation) from just before operation, and checked the satisfaction score of surgeon and patients. RESULT: SpO2 and satisfaction score of surgeon and patients are the best at premedication and oxygen administration group. CONCLUSION: Monitored anesthesia is assumed to give more comfort and safety to patients than local anesthesia alone.

Comparison of Doses of the Epidural Buprenorphine for Postoperative Pain Control after Lower Abdominal Surgery / 대한마취과학회지

Since the first use of epidural morphine in man, a number of other opiates have been studied including fentanyl, pethidine, methadone, diamorphine and buprenorphine. Among them buprenorphine is a relatively new synthetic opiate that is known to be highly lipophilic and to have an affmity for the opiate receptor approximately twice that of morphin:, It is produced in a preservative free solution, and would seem a logical choice for epidural analgesia. But there was no data on the adequate dose for the. postoperative pain control after lower abdominal surgery. Current study was designed to investigate the efficacy of three doses of epidural buprenorphine for postoperative pain control with the checking the pain score. Fifty seven female patients undergoing elective lower abdominal surgery were randomly assigncd to receive epidural buprenorphine as a rate of 0.3 (group A, initial dose 0.15 mg + maintenance dose O.l5 mg), 0.45 (group B, 0.15 mg + 0.3 mg), or 0.6 mg (group C, 0.3 mg + 0.3 mg) utilizing the Two-Day TI4l Infusor during the two days after cessation of operation. Authors compared the efficacy of three doses with checking the pain scale (Facial expression pain scale, Prince Henry pain scale) at 6, 12, 24, and 48 hour postoperatively. Side-effects were recorded. There were no significant difference among three groups with respects to mean age. Analgesic effects for patients receiving 0.6 mg (group C) were superior to those of group A but were not significantly different from analgesic effects of group B except 6 hour postoperatively. Side-effects (nausea and vomiting) of group C were significantly more than group B. The dose of epidural buprenorphine in Group B (initial dose 0.15 mg+maintenance dose 0 3 mg) may be recommended for postoperative analgesia following lower abdominal surgery.

Ligation of Anterior Superrior Sagittal Sinus in Approaching Distal Anterior Cerebral Artery Aneurysm

Interhemispheric approach has been accepted as a standard method approaching distal anterioir cerebral artery(DACA) aneurysm. In the approach, most authors use the surgical method retracting the superior sagittal sinus(SSS) after dural reflection. However, it results in limited surgical space and makes the surgical procedure difficult technically. To overcome the limitation, we tried to ligate and cut SSS in 13 patients out of 23 patients of DACA aneurysm from Mar. 1983 to Feb. 1993. Out of total 583 intracranial aneurysms operated on in that period, the proportion of DACA aneurysm was 3.95%. Mean age was 52.7 years ranging from 32 to 66 years. The sex ration was 7:16, showing female predominancy. As presenting symptoms, twenty two patients had subrachnoid hemorrhage and one patient had a third nerve palsy due to an unruptured posterior communicating artery aneurysm. On admission, 4 patients(17.4%) were in grade I, 10(43.5%) in grade II, 6(26.1%) in grade III, 3(13%) in grade IV according to the Hunt and Hess grading system. In 18 patients(78.3%), aneurysms were located at bifurcation of pericallosal and callosomarginal artery and in 5(21.7%) at bifurcation of frontopolar and pericallosal artery. Associated vascular anomalies were A1 hypoplasia(2 cases), multiple aneurysms(5 cases), fenestration of anterior cerebral(1 case) and arteriovenous malformation(1 case). Thirteen cases were operated on with ligation of the SSS and 10 without ligation. Overall surgical outcomes scored by Glasgow outcome scale were : 11 patients(47.8%) in Grade I, 6(26.1%) in Grade II, 2(8.7%) in Grade III, 4(17.4%) in Grade V. The outcomes in ligation group were : 8 patients(61.5%) in Grade I, 4(30.8%) in Grade II, 1(7.7%) in Grade III, and no death. The outcomes in non-ligation group were : 4 patients(40%) in Grade I, 1(10%) in Grade II, 1(10%) in Grade III, and 4(40%) in Grade V. These results showed that the patients operated on with ligation of SSS had more favorable outcomes than the patients without ligation. It seems that the SSS in the interhemispheric approach might provide several advantages and better operative outcome over the conventional method.

Clinical Evaluation and Follow up on the Pineal Tumors

Authors experienced fifteen cases of the pineal tumors during about 5 years from October, 1977 to September, 1982, which were diagnosed with brain C-T scanning. The details of clinical evaluation and follow up of 15 cases of the pineal tumors are presented. The following results were obtained. 1) The age group below age of 20 years in predominant and include 11 cases(73%) of 15 cases, and male is predominantly much than female. 2) On the neurological examination at admission, the RICP signs were showed in 15 cases, Parinaud's syndrome showed in 6 cases, cranial nerve palsy in 8 cases and DI symptom in 5 cases of all 15 cases. 3) In the follow up study, brain CT was more effective than any other conventional neuroradiologic technique. 4) 8 cases of all 15 cases have had normal life in follow up period with minium of 6 months and maximum of 6 months and maximum of 5 years, and one case with mild neurological deficit has been spent life for about 12 months. 5) Of 6 cases died within 2 years, 3 cases had insufficient treatment and 3 cases had sufficient treatment, of whom ond had tumor recurrence at primary site and dissemination to spinal epidural space and other two cases were suspected to have clinical dissemination to spinal cord. 6) On the basis of high survival rate in 9 cases of 12 cases who were treated completely, we thought that good survival rate in the patient with pinealoma will be resulted from a series of planed treatment, including early diagnosis, correction of hydrocepalus, surgical intervention and irradiation.

Intracranial Subdural Empyema: Report of 2 Cases

Subdural empyema is a neurosurgical emergency the mortality of which continues to be as high as 40% in modern reported series. It is also a curable lesion, and the outcome of treatment has been demonstrated to be directly related to the promptness of diagnosis and appropriate surgical drainage. Recently, we have operated upon two cases of intracranial subdural empyema secondary to acute facial furuncle and postoperative craniectomy. Reviewing these two cases and other literatures, we are going to describe about cases, symptoms and signs, and methods of diagnosis and treatment of subdural empyema.