Transcranial magnetic stimulation-electroencephalography for diagnosis and evaluation in neuropsychiatric diseases / 中华神经医学杂志

The simultaneous recording of transcranial magnetic stimulation electroencephalography (TMS-EEG) can measure the EEG signals of each brain region after receiving magnetic pulse stimulation with high time resolution. Combined with appropriate signal analysis technology, TMS-EEG has important research value in evaluating the excitability of each cortex, concussion activity and connection properties of brain regions. In recent years, the realization equipment and analysis methods of this technology have been rapidly developed, and the application fields have been gradually popularized. In this paper, the TMS-EEG technology and its application in diagnosis and evaluation of neuropsychiatric diseases are summarized as follows.

Chronic pancreatitis affecting the basal levels of several pancreas-related endocrine hormones: a clinical trial / 中华胰腺病杂志

Objective to determine the basal levels of several pancreas-related endocrine hormones in patients with chronic pancreatitis.Methods according to inclusion and exclusion criteria,consecutive patients from February 2016 to August 2016 in Department of Gastroenterology,Changhai Hospital,Second Military Medical University and ten healthy control (matched for age and gender) were included.Basal levels of glucagon-like peptide 1,pancreatic polypeptide,Secretin,glucagon,somatostatin between groups of CP vs healthy control,CP with abnormal glycometabolism vs CP with normal glycometabolism and alcoholic CP vs non-alcoholic CP were compared.Results a total of 53 patients with chronic pancreatitis and 8 healthy subjects were included in this study.(1) CP vs healthy controls:the level of secretin in healthy control patients is significant lower than that in CP patients;(2) CP with abnormal glycometabolism vs CP with normal glycometabolism:the level of triglyceride and somatostatin is significant lower than that in CP patients;the prevalence of patients with chronic alcohol consumption and the level of glucagon-like peptide 1 in CP with abnormal glycometabolism is significant higher than that in CP with normal glycometabolism;(3) the prevalence of abnormal glycometabolism in alcoholic CP group is significant higher than that in non-alcoholic CP.The results above are all of statistical significance.Conclusions in addition to dysfunction of islets/3-cells,CP also easily affects the level of other pancreas-related hormones such as secretin,somatostatin and glucagon-like peptide 1.Otherwise,chronic alcohol consumption is also strongly related with abnormal glycometabolism,the mechanism deserves further researches.