الملخص
Argus Ⅱ retinal prosthesis system (Argus Ⅱ;Second Sight Medical products,Sylmar,CA) is the first prosthetic retinal device approved for humanitarian use by both FDA in America and CE in Europe.It is a potential treatment for patients with end-stage outer retinal diseases.The system contains several parts,the camera first captures image and transfers it into electrical stimulating parameters conveying spatial-temporal information.The microelectrode epiretinal array then stimulate underlying bipolar cells and retinal ganglion cells.Patients present significant increases on levels of discrimination,target localization,motion detection and navigation.Possible adverse events include conjunctival erosion,hypotony and culture-negative presumed endophthalmitis.Future developments of the Argus Ⅱ system will not only comprise upgrading of image processing software and hardware,but also further disclosing retinal and visual signal processing mechanism.
الملخص
Objective To investigate the clinical efficacy of acupuncture plus TDP in treating stageⅡ-Ⅲ pressure sore.Methods Thirty-three patients with pressure sore meeting the inclusion criteria were randomly allocated to treatment and control groups, 17 cases each. Both groups were first given routine clean care. The control group received routine surgical asepsis dressing change and the treatment group, fire needling, surrounding electroacupuncture and TDP irradiation to the affected part. The pressure sore area was observed and the PUSH score was recorded in the two groups before and after treatment. The clinical therapeutic effects were compared between the two groups of patients. Results The total efficacy rate was 88.0% in the treatment group and 71.0% in the control group; there was no statistically significant difference between the two groups (P>0.05). The total efficacy rate was 88.0% in the treatment group and 71.0% in the control group; there was no statistically significant difference between the two groups (P>0.05). The cure and marked efficacy rate was 58.8% in the treatment group and 23.5% in the control group; there was a statistically significant difference between the two groups (P<0.05). There was a statistically significant pre-/post- treatment difference in the pressure sore area in the two groups at one, two and three weeks after treatment (allP<0.05). There was a statistically significant difference in the pressure sore area between the two groups at two and three weeksafter treatment (bothP<0.05). There was a statistically significant pre-/post-treatment difference in the PUSH score in the two groups at two and three weeks after treatment (bothP<0.05). There was a statistically significant difference in the PUSH score between the two groups at three weeks after treatment (P<0.01).Conclusions Acupuncture plus TDP can markedly relieve the clinical symptoms and accelerate the sore healing in treating stageⅡ-Ⅲ pressure sore.