الملخص
Objective To examine the distribution of systemic inflammation and risk factors of cardiovascular disease (CVD) in patients with psoriatic arthritis (PsA) by comparing with healthy controls.Methods Forty PsA patients and 44 controls were recruited into this cross-sectional study.We evaluated the disease activity and severity [erythrocyte sedimentation rate (ESR),C reactive protein(CRP) and Disease Activity Score (DAS)28],functional ability in patients with predominant axial involvement [Bath AS disease activity index (BASDAI) and Bath AS functional index (BASH)],traditional CVD risk factors and inflammation between these two groups of patients.Then,we compared risk factors for CVD between 40 consecutive PsA patients and 44 controls,adjusted for body mass index (BMI).The frequencies were compared using chi-square tests for categorical variables.Student's t-tests or Mann-Whitney U-tests were used forcontinuous variables where appropriate.Association between the traditionaland metabolic risk factors and the hs-CRP level were assessed using Spearman correlations.Finally,we also assessed the role of inflammation on the CVD risk factor by using a BMI and hs-CRP-adjusted model.Results The BMI of PsA patients was significantly higher than that of the controls.After adjusting for the BMI,PsA patients had a higher prevalence of hypertension (OR=5.615,95％CI 1.844-17.099) and diabetes mellitus (OR=10.655,95％CI 1.150-98.683) than the controls.PsA patients had significantly increased systolic and diastolic blood pressures [(SBP) and (DBP)],total cholesterol (TC)/high density lipoprotein cholesterol (HDL),insulin resistance,inflammatory markers (hsCRP,white cell count and platelet) and decreased HDL compared to the controls.As excepted,the hsCRP level [4.0 (2.1-13.9) vs 1.7 (1.3-2.2)],platelet and white cell counts were significantly increased in the PsA group reflecting underlying inflammation.Further adjustment for hsCRP level rendered the differences in the prevalence of hypertension (OR=3.544,95％CI 1.151-10.914);but the DBP,HDL and sugar levels were non-significantly different between the two groups,while the differences in other parameters were significant.Conclusion The data support the hypothesis that PsA may be associated with hypertension,obesity and dyslipidemia because of the shared inflammation pathway.
الملخص
La resonancia mágnetica cardiovascular y la tomografía computarizada de multiples detectores ha evolucionado de una forma muy rápida mostrando una gran utilidad en la práctica clínica de la cardiología en todo el mundo a través de estos últimos años. En nuestro país se ha iniciado una nueva era de la cardiología moderna con el advenimiento de estos nuevos métodos, y es por ello que en este artículo queremos resaltar de una forma clara y resumida cuáles son las alternativas que nos pueden brindar estas herramientas en el diagnóstico y manejo de las enfermedades cardiovasculares.
Cardiovascular magnetic resonance (CMR) and multislice computed tomography (MSCT) have evolved very quickly over the last few years, showing to be very useful in the clinical practice of cardiology around the world. Cardiology has entered a new era in our country with the advent of these new methods, and that is the main reason why we emphasize in this article, in a clear and summary manner, the options that these tools provide in the diagnosis and management of cardiovascular diseases.
الموضوعات
Humans , Cardiovascular Diseases/diagnosis , Cardiovascular Diseases , Magnetic Resonance Spectroscopy/methods , Magnetic Resonance Spectroscopy , Tomography, Emission-Computed/methods , Diagnosis, Computer-Assisted , Diagnostic Equipmentالملخص
Objective To discuss the clinical character,mechanism and prevention of cerebral-cardiac syn-drome(CCS) during acute stroke. Methods 189 patients with CCS caused by acute stroke were Analysed retrospec-tively. Results The incidence rate of CCS following stroke was 55.0%. 84.6% patients with CCS occur in the first 72h. The dead rate of acute stroke with CCS was 26.9%, significartly higher than that of without CCS( P<0.01 ). Conclusion CCS is associated with type and pathologic site of acute stroke. The prognosis of acute stroke with CCS was worse than that without CCS.