Barogenic perforation of the esophagus: An unusual manifestation / Perforación barogénica del esófago: una presentación inusual

Abstract Introduction: Typically, when esophageal perforation secondary to barotrauma is mentioned as the causal pathophysiological mechanism of perforation, the literature refers to spontaneous esophageal perforation or Boerhaave syndrome as an entity. It involves the longitudinal and transmural rupture of the esophagus (previously healthy) secondary to an abrupt increase in intraluminal esophageal pressure, frequently triggered during vomiting. However, in the medical literature, some reports list mechanisms of barotrauma other than this entity. Case report: A 64-year-old female patient with a history of surgically managed gastric adenocarcinoma (total gastrectomy and esophagoenteral anastomosis) presented with stenosis of the esophagojejunal anastomosis, which required an endoscopic dilatation protocol with a CRETM balloon. The third session of endoscopic dilation was held; in removing the endoscope, we identified a deep esophageal laceration with a 4 cm long perforation at the level of the middle esophagus (8 cm proximal to the dilated anastomosis), suspecting the mechanism of barotrauma as the causal agent. She required urgent transfer to the operating room, where we performed thoracoscopic esophagectomy, broad-spectrum empiric antimicrobial coverage, and enteral nutrition by advanced tube during in-hospital surveillance. The control esophagram at seven days showed a small leak over the anastomotic area, which was managed conservatively. Imaging control at 14 days showed a decrease in the size of the leak, with good evolution and tolerance to the oral route. The patient was later discharged.

Resumen Introducción: típicamente, cuando se menciona la perforación esofágica secundaria a barotrauma como el mecanismo fisiopatológico causal de la perforación, la literatura se refiere a la perforación esofágica espontánea o síndrome de Boerhaave como entidad, la cual hace referencia a la ruptura longitudinal y transmural del esófago (previamente sano) secundaria a un aumento abrupto de la presión intraluminal esofágica, que se desencadena frecuentemente durante el vómito. Sin embargo, en la literatura médica existen algunos reportes que mencionan otros mecanismos de barotrauma diferentes a esta entidad. Reporte de caso: se presenta el caso de una paciente de 64 años con antecedente de adenocarcinoma gástrico manejado quirúrgicamente (gastrectomía total y anastomosis esofagoenteral), quien presentaba estenosis de anastomosis esofagoyeyunal, que requirió un protocolo de dilatación endoscópica con balón CRETM. Se llevó a una tercera sesión de dilatación endoscópica, en la que durante la extracción del endoscopio se identificó una laceración esofágica profunda con perforación de 4 cm de longitud a nivel del esófago medio (8 cm proximal a anastomosis dilatada), y se sospechó del mecanismo de barotrauma como agente causal. Requirió traslado urgente a sala de cirugía, en la que se realizó esofagorrafia por toracoscopia, cubrimiento antimicrobiano empírico de amplio espectro y nutrición enteral por sonda avanzada durante la vigilancia intrahospitalaria. El esofagograma de control a los 7 días mostró una pequeña fuga sobre el área anastomótica, la cual se manejó de manera conservadora. El control imagenológico a los 14 días evidenció una disminución del tamaño de la fuga, con una evolución satisfactoria y tolerancia a la vía oral, y posteriormente se dio el egreso.

Complications After endoscopic balloon dilatation of esophageal strictures in children. Experience from a tertiary center in Shiraz - Iran (Nemazee Teaching Hospital) / Complicaciones posteriores a dilatación endoscópica con balón en niños con estenosis esofágica. Experiencia de un centro de referencia en Shiraz - Iran (Nemazee Teaching Hospital)

Background: Esophageal stricture is one of the most important complication of the caustic ingestion. Objective: The aim of this study was to evaluate complications of balloon dilatation among children with esophageal stenosis. Material and methods: In this retrospective study 82 children were included. Children who underwent balloon dilatation for esophageal stenosis were included in our study. Duration of study was 14 year starting from 2001. Mean age of the cases was 3.95±0.4 year (Min: 15 days, Max: 14 year). Chart review and telephone calling were the methods of data collection. Data was analyzed using SPSS. Results: In this study, 47% of the patients were male and 53% of the cases were female. Caustic ingestion (33.7%) was the most common etiology for the esophageal stricture. Vomiting (87.8%) was the most common presenting symptom. Among our cases, 76.8% had no compliant after esophageal dilatation. Chest pain was the most common compliant after esophageal dilatation. Response rate was similar among boys and girls. Toddler age had the best treatment response after esophageal dilatation. Conclusion: Among our cases, 76.8% had no post procedural compliant after esophageal dilatation. Esophageal perforation was seen in 4.9% of the cases. Chest pain was the most common post dilatation complication.

Antecedentes: La estenosis esofágica es una de las más importantes complicaciones de la ingesta de caústicos. Objetivo: El objetivo del estudio fue evaluar las complicaciones de la dilatación endoscópica con balón en niños con estenosis esofágica. Material y métodos: En este estudio retrospectivo se incluyeron 82 niños. Se incluyeron todos los niños que se sometieron a una dilatación endoscópica con balón por estenosis esofágica. La duración del estudio fue 14 años iniciando en el año 2001. La edad media de los pacientes fue 3,95 +/- 0,4 años (Min. 15 días, Máx. 14 años). La recolección de datos se realizó revisando las historias clínicas y con llamadas telefónicas. Los datos se analizaron con el Sistema SPSS. Resultados: En este estudio, 47% de los casos fueron varones y 53% fueron mujeres. La ingesta de caústicos fue la causa más frecuente de estenosis esofágica (33,7%). El síntoma más común fueron los vómitos (87,8%). Entre nuestros casos, 76,8% no presentaron molestias luego de la dilatación esofágica. El dolor torácico fue la molestia más común luego de la dilatación esofágica. La tasa de respuesta al tratamiento fue similar entre hombres y mujeres. Los niños pequeños tuvieron la mejor respuesta al tratamiento luego de la dilatación esofágica. Conclusiones: Entre nuestros casos, 76,8% no presentaron molestias luego de la dilatación esofágica. La perforación esofágica se presentó en 4,9% de los casos. El dolor torácico fue la complicación más común posterior a la dilatación.

Perforación esofágica durante el monitoreo intraoperatorio con ecocardiografía transesofágica. Reparación en el mismo acto quirúrgico / Esophageal injury secondary to transesophageal ecocardiography monitoring and repair

Monitoring with intraoperative Transesophageal Echocardiography (TEE) has proven to be a tool of very high utility for both control of the hemodynamic status, cardiac function and to make new diagnoses. It is a minimally invasive technique and, like any medical procedure, it is not exempt from complications that do not exceed 1%. These range from mild oropharyngeal lesions to the most serious lesion, esophageal perforation. We describe a case of esophageal perforation from the esophagogastric junction to the middle third of the esophagus in the intraoperative period of laparoscopic Nissen surgery. The injury was repaired immediately and the closure of the lesion was verified with pneumatic maneuvers through the nasogastric tube. The patient was discharged after 35 days

El monitoreo con Ecocardiografía Transesofágica intraoperatorio (ETE) ha demostrado ser una herramienta de muy alta utilidad tanto para control del estado hemodinámico, función cardíaca y para realizar nuevos diagnósticos. Se trata de una técica seiinvasiva y como todo procedimiento médico no está exento de complicaciones que no superan al 1%. Estas son desde lesiones leves orofaríngeas hasta la lesión más grave que es la perforación esofágica. Se describe un caso de perforación esofágica con desgrarro de éste desde la unión esofagogástrica hacia el tercio medio del esófago en el íntraoperatorio de cirugía de Nissen laparoscópico. La reparación de la injuria se realizó en forma inmediata y se comprobó con maniobras neumáticas a través de la sonda nasogástrica el cierre de la lesión. La paciente fue dada de alta a los 35 días.

Perforación esofágica cervical tardía por rotura y desplazamiento de placa de artrodesis cervical anterior / Delayed cervical esophageal perforation by rupture and displacement of anterior cervical arthrodesis plaque

Resumen Introducción: La perforación esofágica es una posible complicación de la artrodesis cervical anterior. Sin embargo, estas suelen ocurrir intraoperatoriamente o en el posoperatorio precoz. Caso clínico: Mujer de 35 años sometida, 3 años antes, a artrodesis de C3-C5, que tras sufrir un traumatismo leve con latigazo cervical, comienza con disfagia. Se objetiva un absceso retroesofágico por perforación esofágica, causado por rotura de la placa protésica y extrusión de un tornillo.

Introduction: Esophageal perforation is a possible complication after anterior cervical fusion. However, these complications usually appear intraoperatively or in the early postoperative course. Case report: A 35-years-old females, who underwent a C3-C5 anterior cervical fusion 3 years ago, after suffering a mild cervical trauma, she complained of dysphagia. A retroesophageal abscess was observed, caused by esophageal perforation, secondary to plaque rupture and screw extrusion.

Mortalidad a causa de perforación esofágica por mediastinitis aguda / Mortality due to esophageal perforation caused by acute mediastinitis

En situaciones de urgencia, la cirugía constituye un desafío a la pericia de los cirujanos, sobre todo cuando se trata de la perforación del esófago, que es una de las roturas orgánicas más graves y complejas de todo el tracto digestivo. Esto ocurre debido a las características anatómicas del órgano, que además, está rodeado de tejidos laxos y cavidades fasciales virtuales; por ello, su perforación permite que la infección se disemine rápidamente en el mediastino, la pleura y el pericardio, lo cual provoca que la mortalidad por mediastinitis aguda sobrepase el 60 por ciento.

Surgery constitutes a challenge to surgeons skill, in situations of emergency mainly when it is an esophageal perforation which is one of the most serious and complex organic breaks in the whole digestive tract. This happens due to the anatomical characteristics of the organ that is also surrounded by relaxed tissues and virtual fascia cavities; reason why, its perforation allows the infection to be quickly disseminated in the mediastinal cavity, pleura and pericardium, which causes that mortality due to acute mediastinitis exceeds the 60 percent.

Efficacy of surgical versus conservative treatment in esophageal perforation: a systematic review of case series studies

PURPOSE: To evaluate the efficacy of surgical treatment for esophageal perforation. METHODS: A systematic review of the literature was performed. We conducted a search strategy in the main electronic databases such as PubMed, Embase and Lilacs to identify all case series. RESULTS: Thirty three case series met the inclusion criteria with a total of 1417 participants. The predominant etiology was iatrogenic (54.2%) followed by spontaneous cause (20.4%) and in 66.1% the localization was thoracic. In 65.4% and 33.4% surgical and conservative therapy, respectively, was considered the first choice. There was a statistically significance different with regards mortality rate favoring the surgical group (16.3%) versus conservative treatment (21.2%) (p<0.05). CONCLUSION: Surgical treatment was more effective and safe than conservative treatment concerning mortality rates, although the possibility of bias due to clinical and methodological heterogeneity among the included studies and the level of evidence that cannot be ruled out.

Boerhaave's syndrome: a differential diagnosis of acute chest pain following a vomiting illness / Síndrome de Boerhaave: un diagnóstico diferencial de dolor torácico, agudo tras enfermedad acompañada de vómitos

Spontaneous oesophageal rupture (Boerhaave's syndrome) is extremely rare in children. Presentation is usually in middle aged men as a result of vomiting following heavy food or alcohol consumption. We describe an unusual case of a 12-year old boy without significant past medical history presenting with acute chest pain following gastroenteritis.

La ruptura esofágica espontánea (síndrome de Boerhaave) es extremadamente rara en niños. Por lo general se presenta en hombres de mediana edad como resultado vómitos tras la ingestión de alcohol o alimentos pesados. Describimos un caso inusual de un niño de 12 años de edad sin antecedentes clínicos significativos, que acudió con dolor torácico agudo tras una gastroenteritis.

Comparison of Complications between Endoscopic and Percutaneous Replacement of Percutaneous Endoscopic Gastrostomy Tubes

When replacing percutaneous endoscopic gastrostomy (PEG) tubes, an internal bolster may be retrieved either percutaneously or endoscopically. The aim of this study was to compare the complications of percutaneous and endoscopic method during PEG tube replacement. The medical records of 330 patients who received PEG tube replacement were retrospectively analyzed. According to the removal method of internal bolster, we categorized as endoscopic group and percutaneous group. Demographic data, procedure-related complications and risk factors were investigated. There were 176 cases (53.3%) in endoscopic group and 154 cases (46.7%) in percutaneous group. The overall immediate complication rate during PEG tube replacement was 4.8%. Bleeding from the stoma (1.3%) occurred in percutaneous group, whereas esophageal mucosal laceration (7.4%) and microperforation (0.6%) occurred in endoscopic group. The immediate complication rate was significantly lower in the percutaneous method (OR, 6.57; 95% CI, 1.47-29.38, P=0.014). In multivariate analysis, old age was a significant risk factor of esophageal laceration and microperforation during PEG tube replacement (OR, 3.83; 95% CI, 1.04-14.07, P=0.043). The percutaneous method may be more safe and feasible for replacing PEG tubes than the endoscopic method in old patients.

[Lateral esophagostomy with thoracic drainage in treatment of esophageal perforation]

Esophageal perforation is a true emergency caused by instrumentation, spontaneous rupture known as Boerhaave syndrome, foreign bodies, and trauma. For patients with an early diagnosis [less than 24 hours], the primary repair is performed and in case of delayed diagnosis the end esophagostomy with thoracic drainage and tube jujunostomy is the treatment of choice. The aim of this study was to evaluate the surgical technique of lateral esophagostomy with thoracic drainage in treatment of esophageal perforation. This cross-sectional study was performed based on information derived from three patients admitted to the emergency ward of Shahid Rajaei hospital in Qazvin with the diagnosis of esophageal perforation who underwent lateral esophagostomy with thoracic drainage and tube jujunostomy. Three patients with esophageal perforation caused by foreign bodies or Boerhaave syndrome underwent surgery with lateral esophagostomy, thoracic drainage, and tube jujunostomy technique. Following surgery, the patients were transferred to ICU and all recovered. This study confirms that patients with esophageal perforation, who undergo lateral esophagostomy, thoracic drainage, and tube jujunostomy, make a good recovery soon after a simple and short duration surgery without invasive surgical procedure

Uso de colgajos musculares en las perforaciones traumáticas del esófago / Use of muscular flaps to repair traumatic esophageal perforations: report of two cases

The management of esophageal perforations is variable, ranging from conservative management to esophageal excision. Muscular flaps are used specially when there are associated lesions in trachea or aorta. We report two patients managed using this last technique. A 31 years old woman that received a gun shot in the neck that was operated, repairing two tracheal and two esophageal perforations. The patient had to be reoperated 28 days later, due to a dehiscence of the esophageal suture. A muscular flap was used to repair the lesion with a good postoperative evolution. A 17 years old male that received a gunshot in the left supraclavicular region. Eight days later, he was operated, draining a right empyema and repairing an esophageal perforation using a muscular flap. The patient had a good postoperative evolution.

Las perforaciones del esófago, especialmente las de manejo tardío, representan un dilema y un reto para el cirujano. El manejo de las perforaciones tardías ha sido controversial y las opciones terapéuticas incluyen desde manejo conservador y simple drenaje hasta la resección del esófago. Se presentan 2 casos de perforaciones esofágicas producidas por proyectil de arma de fuego referidos a los 28 y 8 días respectivamente. En ambos se realizó reparación primaria reforzada con colgajo muscular.

Esophageal Cancer with Esophageal Perforation / 대한소화기학회지

No abstract availble.

Conservative management of esophageal perforation following obesity surgery

CONTEXT: Laparoscopic adjustable silicone gastric banding (LASGB) is one of the several surgical techniques for treating patients with morbid obesity. Erosion and perforation in the gastric chamber caused by LASGB are rare complications that have already been described. There have not yet been any reports of perforation of the middle esophagus during this procedure. CASE REPORT: The authors describe the case of a patient who presented the complication of very extensive perforation of the middle third of the esophagus following LASGB. This was successfully managed using conservative treatment.

CONTEXTO: Banda gástrica laparoscópica ajustável de silicone (LASGB) é uma das várias técnicas cirúrgicas para o tratamento de pacientes com obesidade mórbida. A erosão e a perfuração para o interior da câmara gástrica causados pela LASGB são complicações raras já descritas. Não se encontram relatos de perfuração do esôfago médio durante esse procedimento. RELATO DE CASO: Descrevemos o caso de uma paciente que apresentou como complicação, uma perfuração extensa do esôfago médio após LASGB, submetida a tratamento conservador com sucesso absoluto.

Management of delayed diagnosed esophageal perforation

The esophageal perforation can be fatal unless diagnosed promptly and treated effectively. The high mortality rate related to delayed treatment is due to an inability to effectively close the perforation site to prevent leakage and ongoing sepsis. This study was performed on patients who were referred to three hospitals of Shaheed Beheshti and Tehran Universities of Medical Sciences during two years. All patients admitted in these hospitals with esophageal perforation lasting for more than 24 hours were studied. There were 24 patients [12 males, 12 females] with the mean age of 37.5 yrs. The most frequent symptoms and signs were: Chest and abdominal pain in 11 cases [45.83%], empyema in 11 cases [45.83%], fever in 10 cases [41.66%], pleural effusion in 8 cases [33.33%] and emphysema in 3 cases [12.5%]. The most common causes of esophageal perforation were use of devices during esophagoscopy and foreign bodies in 13 cases [54.17%], iatrogenic trauma in 4 cases [16.67%], Boerhaave's syndrome in 4 cases [16.67%], ingestion of burning chemicals in 2 cases [8.33%] and esophageal cancer in 1 case [4.17%].Four [16.66%] of all patients died while others were discharged with no significant complication in long time. This study was performed on patients referred to university hospitals; therefore, the results are different from those of community. Most of the perforations were due to intraoperative negligence or device manipulation. The outcomes of the whole procedures were good concluding that late diagnosed esophageal perforations can be managed surgically with good results but with a longer period of hospitalization

Perforación esofágica: experiencia clínica y actualización del tema / An update on esophageal perforation

Esophageal perforation is a complicated clinical entity that demands a high level of diagnostic and therapeutic skills. The management alternatives vary from conservative treatment to esophagectomy, including primary suture and esophageal exclusion. This paper is a review of the literature and personal experience with this condition, focusing on etiology, clinical presentation, diagnostic workout, treatment, complications and mortality. Finally, we propose a management algorithm.