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مقالة ي الانجليزية | IMSEAR | ID: sea-30781

الملخص

Cysticercus cellulosae extract (CS), cyst fluid (CF), and an extract of Taenia saginata adult worm (TS) were evaluated for use in an enzyme-linked immunosorbent assay (ELISA) for serodiagnosis of human neurocysticercosis in Thai patients. ELISA sensitivity was found to be 78.13%, 81.25% and 62.50%, respectively. False positivity was 6.66% with CS and 0% with other antigens. CF gave positivity with a pooled visceral gnathostomiasis serum and 3 of 10 (30%) of angiostrongyliasis sera. CS produced weakly positive ELISA with pooled opisthorchiasis and visceral gnathostomiasis sera. TS gave weak positive ELISA with a pooled opisthorchiasis serum. It was concluded that CF was the best antigen for use in ELISA for serodiagnosis of human neurocysticercosis.


الموضوعات
Adolescent , Adult , Animals , Antigens, Helminth/blood , Brain Diseases/blood , Cysticercosis/blood , Cysticercus/chemistry , Enzyme-Linked Immunosorbent Assay/methods , Evaluation Studies as Topic , Female , Hospitals, University , Humans , Immunoglobulin G/immunology , Male , Middle Aged , Prevalence , Sensitivity and Specificity , Taenia/chemistry , Thailand/epidemiology , Tissue Extracts/diagnosis
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