Tratamento endovascular de síndrome congestiva venosa pélvica em paciente com duplicação de veia cava inferior e anatomia venosa pélvica incomum: revisão bibliográfica / Endovascular treatment of pelvic venous congestion syndrome in a patient with duplication of the inferior vena cava and unusual pelvic venous anatomy: literature review

Resumo A dor pélvica crônica afeta aproximadamente 1/3 de todas as mulheres e é responsável por cerca de 20% de todas as consultas ginecológicas. Os autores relatam um raro caso de congestão venosa pélvica sintomática na presença de duplicação de veia cava inferior e comunicação interilíaca através de veia hipogástrica direita tratado com abordagem endovascular, por embolização das veias varicosas pélvicas e revisão da literatura publicada.

Abstract Chronic pelvic pain affects approximately one-third of all women and is responsible for about 20% of all gynecological consultations. The authors report a rare case of symptomatic pelvic venous congestion in the presence of duplication of the inferior vena cava and inter-iliac communication through the right hypogastric vein that was treated via an endovascular approach with embolization of varicose pelvic veins. The published literature is reviewed.

Evaluación del conocimiento anátomo-quirúrgico del sistema de la vena cava inferior por médicos residentes de cirugía general / Evaluation of anatomical and surgical understanding of the inferior vena cava system by general surgery interns

Las lesiones de vena cava inferior (VCI) han sido descritas como la lesión vascular abdominal mas frecuente encontradas en los centros de trauma. Puede lesionarse entre la supra e infrarrenal; y en el caso de lesión retrohepática, se asocia con alta mortalidad. En heridas penetrantes conllevan una elevada mortalidad. Hasta un 50 % de los individuos que experimentan estas lesiones muere antes de llegar al hospital; y la tasa de mortalidad entre los que llegan con vida a un centro de trauma varía entre 20­57 %. Se evaluaron a 12 cirujanos en formación, respecto de los conocimientos anatómicos del sistema de la VCI y sus relaciones, con material cadavérico formalizado mediante listas de verificación (Abril/2014). Luego de un período de entrenamiento mediante la disección anatómica de 10 cadáveres formolizados (Mayo/2014-Agosto/2014); se realizó una nueva evaluación de los médicos residentes de cirugía general en formación mediante listas de verificación, con material cadavérico fresco (Septiembre/2014). Durante la primera evaluación la vena iliaca común derecha e izquierda, fueron identificadas por 8 (66,66 %) residentes. Siete (58,33 %) mencionaron los segmentos de la VCI en intratorácico y abdominal. Seis (85,71 %) mencionaron la porción intrapericárdica y uno (14,29 %) la porción extrapericárdica. La porción o segmento subduodenal fue identificado como subhepático por siete (58,33 %) residentes; y solo dos (16,66 %) mencionaron los segmentos subduodenal, retroduodenopancreático y supraduodenopancreático como parte del segmento subhepático. Tres (25 %) no mencionaron los diferentes segmentos de la VCI (abdominal). El segmento retrohepático fue identificado por ocho (66,66 %). Durante la segunda evaluación la vena iliaca común derecha e izquierda, fueron identificadas por todos los residentes. Once (91,66 %) mencionaron los segmentos de la VCI en intratorácico y abdominal, además de la porción intrapericárdica y la porción extrapericárdica. El segmento subduodenal fue identificado como subhepático por dos (16,66 %) residentes; y nueve (75 %) mencionaron los segmentos subduodenal, retroduodenopancreático y supraduodenopancreático como parte del segmento subhepático. El segmento retrohepático fue identificado por once (91,66 %) residentes. La observación y disección anatómica de la VCI en material cadavérico durante la formación del cirujano general, brinda un importante método de enseñanza, capacitación y entrenamiento hacia el reconocimiento de las diferentes estructuras anatómicas de la región, pudiendo luego ser aplicado en cirugía. La metodología de supervisión y evaluación mediante listas de verificación, por médicos especialistas, es una opción a agregar a los programas de formación para mejorar el proceso de educación.

Injuries in the inferior vena cava (IVC) have been described as the most common vascular abdominal injury found in trauma. The injury may present between the suprarenal and the infrarenal; in the case of retrohepatic injuries, it is associated with a high mortality rate. In a penetrating wound, high mortality rates are reported. Up to 50% of the individuals who experience these injuries die before getting to the hospital, and the mortality rate among those who get to a healthcare facility alive, ranges from 20 to 57 %. The study involved the evaluation of 12 trainee surgeons concerning anatomical understanding of the inferior vena cava system and related areas, using corpses subject to 10 % formol via checklists (April 2014). After a training period with anatomical dissection of 10corpses subject to 10 % formol (May 2014-August 2014), the general surgery interns were reassessed via checklists using fresh corpses fresco (September 2014). During the first evaluation, the right and left common iliac vein were identified by 8 (66.66 %) interns: 7 (58.33 %) mentioned the segments of the IVC in the intrathoracic and abdominal area; 6 (85.71 %) referred to the intrapericardial portion, and 1 (14.29 %) mentioned the extrapericardial portion. The subduodenal portion or segment was identified as subhepatic by 7 (58.33 %) interns, and only 2 (16.66 %) referred to the subduodenal, retroduodenopancreatic and supraduodenopancreatic segments as part of the subhepatic segment. 3 (25 %) failed to mention the various segments of the (abdominal) IVC. The retrohepatic segment was identified by 8 (66.66 %) interns. During the second evaluation, the right and left common iliac vein were identified by 12 (100 %) interns: 11 (91.66 %) mentioned the segments of the inferior vena cava in the intrathoracic and abdominal areas; 11 (91.66 %) interns referred to the intrapericardial and the extrapericardial portions. The subduodenal segment was identified as subhepatic by 2 (16.66 %) interns, and 9 (75 %) of them mentioned the subduodenal, retroduodenopancreatic and supraduodenopancreatic segments as part of the subhepatic segment. The retrohepatic segment was identified by 11 (91.66 %) interns. Observation and anatomical dissection of the IVC in corpses when training a general surgeon provides a major teaching and training method to recognize the different anatomical structures of the area, for subsequent its application to surgery. The supervision and evaluation methodology consisting of the use of checklists by specialist physicians is an option that should be added to training programs in order to improve the educational process.

Morphometric analysis of the inferior vena cava related to lumbar vertebra and the aortic bifurcation on Multidetector Computed Tomography (MDCT) / Análisis morfométrico de la vena cava inferior relacionado con las vértebras lumbares en la bifurcación aórtica mediante Tomografía Computadorizada Multidetector (TCMD)

Vascular structures are in greater danger during lumbar surgery. The purpose of this study is to describe the morphology of the inferior vena cava (IVC) related to the lumbar vertebra and aortic bifurcation (AB) and assessing the role of demographic values in these relations to decrease the risk of complications in the surgical interventions. The study was performed on Multidetector Computed Tomography (MDCT) images of 100 male and 100 female cases with an age range from 50 to 84 years. The morphometric values of the IVC obtained from the coronal, sagittal and the axial reformatted images were measured and compared with the demographic values. The distance from the IVC to the 1st lumbar vertebra (L1) and 2nd lumbar vertebra (L2) were measured as (26.5 mm and 18.1 mm) in males and (21.1 mm and 14.2 mm) in females with a high level of significance between genders; the distance from the IVC to the iliocaval confluence (IC), 3rd lumbar vertebra (L3) and 4rd lumbar vertebra (L4) were measured as (6.5 mm, 10.5 mm and 6.9 mm) in males and (4.9 mm, 9.1 mm and 5.5 mm) in females with significance between genders. The level of the IC was detected 46 % of males, 39 % of females at the level of lower third of L4. The vertical distance between the IC and the AB was measured and negative correlation between genders based on age was detected. Demographic values are important to consider the relationship of the IVC, the lumbar vertebra and the AB. The IVC was located further from the lumbar vertebra in males compared to females. Age increase played role in the approaching of the AB and the IC to each other in both gender and the IC to the promontory level in males.

Las estructuras vasculares corren gran peligro durante la cirugía lumbar. El propósito de este estudio fue describir la morfología de la vena cava inferior (VCI) en relación con las vértebras lumbares y la bifurcación aórtica (BA), junto con evaluar los valores demográficos de estas relaciones para disminuir el riesgo de complicaciones en las intervenciones quirúrgicas. Se utilizaron tomografías computadorizadas multidetector (TCMD) de 100 casos de hombres y mujeres entre 50 a 84 años de edad. Los valores morfométricos de la VCI se obtuvieron desde imágenes coronales y sagitales reformateadas, medidas y comparadas con los valores demográficos. Se midió la distancia de la VCI a la 1a (L1) y 2a vértebra lumbar (L2), en hombres de 26,5 mm y 18,1 mm respectivamente, y en mujeres de 21,1 mm y 14,2 mm, respectivamente, con un alto nivel de significancia entre el sexos. La distancia desde la VCI a la confluencia iliocava (CI), 3a (L3) y 4a vértebra lumbar (L4) fue para los hombres de 6,5 mm, 10,5 mm y 6,9 mm, respectivamente, y en mujeres de 4,9 mm, 9,1 mm y 5,5 mm respectivamente, con significancia entre los sexos. El nivel de la IC se detectó en 46 % de los varones y en el 39 % de las mujeres, a nivel de tercio inferior de L4. La distancia vertical entre la CI y la BA se tuvo una correlación negativa entre sexos en base a la edad. Los valores demográficos son importantes al considerar la relación de la VCI, las vértebras lumbares y la BA. La VCI se encuentra a una distancia mayor de las vértebras lumbares en hombres que en mujeres. El incremento de la edad jugó un papel importante en la aproximación de la BA y la IC, tanto entre sí como según sexo, con la CI a nivel del promontorio en los hombres.

Descrição morfológica do diafragma do sagui-de-tufo-branco (Callithrix jacchus) / Morphological description of diaphragm of white-tufted-ear-marmoset (Callithrix jacchus)

O músculo diafragma, encontrado apenas nos mamíferos, é o principal músculo no processo respiratório, servindo de fronteira entre as cavidades torácica e abdominal. Sua importância também ganha destaque em pesquisas realizadas no âmbito dos enxertos, empregando-se diversos tipos de membranas biológicas para o reparo de defeitos diafragmáticos, os quais podem gerar hérnias diafragmáticas. Apesar de muitos estudos já conduzidos para com os primatas não humanos, especialmente no que tange a espécie do novo mundo Callithrix jacchus (Sagui-de-tufo-branco), oriundo do nordeste brasileiro, as pesquisas envolvendo o uso do diafragma em tal espécie é inexistente. Deste modo objetivou-se caracterizar a morfologia e a biometria do diafragma na espécie Callithrix jacchus de ambos os sexos, analisando possíveis divergências estruturais entre machos e fêmeas. Para tal foram utilizados quatros animais, 2 machos e 2 fêmeas, adultos, que vieram a óbito por causas naturais, provenientes de um criadouro comercial. Após fixação em solução de formaldeído 10% os animais foram devidamente dissecados para fotodocumentação e em seguida o diafragma coletado para efetuação da biometria (comprimento e largura) com o uso de um paquímetro e para o processamento histológico por meio da coloração de hematoxilina-eosina e tricrômio de masson, da porção muscular. As mensurações feitas permitiram concluir que não houve diferenças signifcativas entre machos e femeas. A topografia e a presença de três aberturas (forame da veia cava caudal, hiato aórtico e esofágico) na extensão do diafragma corroboram com descrições na literatura classica para outros mamíferos. A presença de um centro tendíneo em "V" difere do encontrado para animais como o peixe-boi e porquinho-da-india, mas é similar ao encontrado para o gambá-de-orelhas-brancas e rato albino. No que diz respeito aos achados histológicos conclui-se que as fibras musculares estão dispostas de forma organizada, apresentam diâmetro grande e núcleos basais, tendo, portanto, características similares do músculo estriado esquelético tanto nos animais machos como nas fêmeas.

The diaphragm muscle found only in mammals is the main muscle in the respiratory process, serving as the border between the thoracic and abdominal cavities. Its significance also is highlighted in research conducted with grafts using various types of biological membranes for the repair of diaphragmatic defects which may cause diaphragmatic hernias. In spite of many studies already conducted in non-human primates, especially in regard to the new world species Callithrix jacchus (white-tufted-ear-marmoset) from northeastern Brazil, research involving use of the diaphragm in such species is nonexistent. Thus, the objective was to characterize the morphology and biometry of the diaphragm in C. jacchus of both sexes, analyzing possible structural differences between males and females. To this end, we used four adult white-tufted-ear-marmosets from a commercial breeder, two males and two females that had died of natural causes. After fixed in 10% formaldehyde solution, the animals were dissected for photo documentation, the diaphragm was collected for biometrics (length and width) with a caliper, and for histological processing by hematoxylin-eosin and Trichrome Masson. The measurements showed that there were no significant differences between males and females. The topography and the presence of three openings (foramen vena cava, aortic et esophageal hiatus) in the extension of the diaphragm corroborate descriptions in classical literature for other mammals. Regarding the histological findings, it was concluded that the muscular fibers are arranged in an organized shape, with a large diameter and basal nuclei, and showed similar characteristics of skeletal muscle in males and females.

Duplication of the inferior vena cava: case report and a literaturereview of anatomical variation

Anatomical variation in the inferior vena cava can result in misdiagnosis, making a better understanding of suchvariations crucial. Here we report the case of a 29 year-old male, victim of multiple trauma, who in the courseof treatment presented with a pulmonary thromboembolism confirmed by tomography. Given the gravityof the situation and the need for additional surgeries, a decision was made to implant an inferior vena cavafilter. During phlebography, prior to implantation of the filter, the duplication of the vena cava was detectedand classified as a complete duplication. A review of the literature revealed various anatomical descriptions ofduplicated inferior vena cava, the most common of which were incomplete cases showing greater variationin venous contion. All in vivo anatomical descriptions were done via phlebography, demonstrating the valueof this test for the diagnosis of anatomical variation in the abdominal veins. While duplication of the inferiorvena cava was not the cause of the venous thrombosis in our patient, a detailed phlebography test was neededto both identify the anatomical variation and facilitate the placement of the filter to prevent a new pulmonarythromboembolism.

Formation of the azygos vein / Formación de la vena ácigos

The aim of the present study was to determine the most common origin of the azygos vein. Thirty cadavers male and female, white and non-white adult individuals of different ages fixed in 10 percent formaldehyde and dissected. All cadavers had an undisclosed clinical death and were donated to the Universidade Estadual de Ciências da Saúde de Alagoa s, Brazil. Eleven different formations were found. The right subcostal vein was was only observed in 13 cases (43.33 percent); the azygos vein was formed by the confluence of the right subcostal and right ascending lumbar vein in three cases (10 percent); by the right subcostal vein with a contribution from the inferior vena cava (IVC) in three cases (10 percent); by the right subcostal with contribution from IVC and right ascending lumbar vein in three cases (10 percent); by the right and left subcostal veins in two cases (6.66 percent); by the right and left subcostal veins and contribution from the IVC in one case (3.33 percent); by the right and left subcostal veins and left accessory renal vein in one case (3.33 percent); by the left renal vein in one case (3.33 percent); by the right subcostal and left gonadal veins with contribution from the IVC in one case (3.33 percent); by the right subcostal and left renal veins in one case (3.33 percent); and composed by the continuation of the 11th posterior intercostal vein in one case (3.33 percent). Based on the results, the right subcostal vein was the only structure with a significant presence in the formation of the azygos vein.

El objetivo del estudio fue verificar cual es la disposición más frecuente del origen de la vena ácigos. Fueron disecados 30 cadáveres de individuos adultos, de ambos sexos, de diferentes grupos étnicos, fijados en formaldehído al 10 por ciento, donados a la Universidade Estadual de Ciencias da Saúde de Alagoas. Se encontraron 11 formaciones diferentes. En 13 casos (43,33 por ciento) se observó sólo la vena subcostal derecha; en 3 casos (10 por ciento) la vena ácigos estaba formada por la confluencia de las venas subcostal derecha y lumbar ascendente derecha; en 3 casos (10 por ciento) formado por las venas subcostal derecha y una contribución de la vena cava inferior VCI; en 3 casos (10 por ciento) por las venas subcostal derecha y contribución de la VCI y lumbar ascendente derecha; 2 casos (6,66 por ciento) por las venas subcostales derecha e izquierda; en 1 caso (3,33 por ciento) por las venas subcostal derecha, izquierda y contribución de la VCI; en 1 caso (3,33 por ciento) por las venas subcostal derecha e izquierda y renal accesoria izquierda; en 1 caso (3,33 por ciento) por la vena renal izquierda; en1 caso (3,33 por ciento) por las venas subcostal derecha, gonadal izquierda y contribución de la VCI; en 1 caso (3,33 por ciento) por las venas subcostal derecha y renal izquierda y en 1 caso (3,33 por ciento) por la continuación de la 11 vena intercostal posterior. Con base en los resultados podemos concluir que la vena subcostal derecha fue la única estructura con presencia significativa en la formación de la vena ácigos.

Persistência da veia ciática / Persistent sciatic vein

CONTEXTO: Durante um período da vida embrionária, a veia ciática é a principal coletora do membro inferior. Na embriogênese vascular, há diferenciação dos angioblastos em um plexo vascular primitivo, com posterior remodelagem e expansão. Consequentemente, durante esse processo, podem ocorrer anomalias. Quando ocorre persistência da veia ciática, esta pode se comunicar com a veia safena parva ou com a veia poplítea durante seu percurso, anastomosando-se com a veia perfurante superior e com a veia circunflexa medial do fêmur. OBJETIVO: Relatar o caso da persistência bilateral de veia ciática nos membros inferiores, comparando à literatura. MÉTODOS: Foram dissecados 32 membros inferiores de 16 cadáveres formolizados no Laboratório de Anatomia pela Disciplina de Anatomia Topográfica da Faculdade de Medicina da Universidade de Santo Amaro (Unisa), durante 2006 e 2007, observando-se em 2 membros inferiores de um único cadáver, a presença de veia ciática. RESULTADOS: No membro inferior esquerdo de um cadáver que apresentou a anomalia bilateralmente, a veia media 37 cm, tinha origem na região da veia poplítea, acompanhava o nervo ciático, perfurava o músculo adutor magno e desembocava na veia femoral profunda. No membro inferior direito, ela media 36 cm, originava-se recebendo as veias do compartimento tibial anterior, acompanhava o nervo ciático, perfurava o músculo adutor magno e desembocava na veia ilíaca interna. CONCLUSÃO: As variações anatômicas do sistema venoso do membro inferior são as mais prevalentes. A persistência da veia ciática pode causar insuficiência venosa crônica no membro inferior e, dessa forma, deve ser investigada para uma melhor conduta clínica ou cirúrgica.

BACKGROUND: During a period of the embryonic life, the sciatic vein is the main lower limb collector. In vascular embryogenesis, there is a differentiation of the angioblasts in a primitive vascular plexus, with posterior remodeling and expansion. Consequently, anomalies may occur during this process. When there is persistence of the sciatic vein, it may communicate with the small saphenous vein or with the popliteal vein during its route, being anastomosed to the superior perforating vein and to the medial circumflex femoral vein. OBJECTIVE: To report a case of bilateral persistent sciatic vein on the lower limbs in comparison to the literature. METHODS: Thirty-two lower limbs from 16 corpses preserved in formaldehyde were dissected at the Laboratory of Anatomy of the discipline of Topographic Anatomy of the Medical School of Universidade Santo Amaro (Unisa), during 2006 and 2007, and the sciatic vein was observed in 2 lower limbs of one single corpse. RESULTS: On the left lower limb of a corpse that presented bilateral anomaly, the vein had 37 cm, emerging on the popliteal vein, accompanying the sciatic nerve, perforating the long adductor muscle and leading into the deep femoral vein. On the right lower limb, it measured 36 cm, emerged receiving the veins of the anterior tibial compartment, accompanied the sciatic nerve, perforated the long adductor muscle and led into the internal iliac vein. CONCLUSION: The anatomical variations of the lower limb venous system are the most common ones. The persistent sciatic vein may cause chronic venous failure in the lower limbs and, in this manner, must be investigated aiming at a better clinical or surgical management.

Aspectos biométricos y morfológicos del pericardio fibroso y diafragma en el hombre / Biometric and morphological charachteristics of the fibrous pericardium and the diaphragm in man

El pericardio es una membrana fibro-serosa que envuelve al corazón y a la porción yuxtacardíaca de los grandes vasos. Realizamos un estudio del pericardio y del diafragma, registrando sus dimensiones, sus relaciones, así como también, establecer el tipo de conexiones existente entre ambas estructuras. Fueron disecadas 142 regiones mediastínicas de cadáveres sin fijación o con fijación en formaldehído al 10 por ciento, brasileños, adultos, de ambos sexos, de edades comprendidas entre los 18 y 70 años, fallecidos de diferentes causas. Para el estudio histológico, del conjunto pericardio y diafragma fueron retirados cinco fragmentos de diferentes regiones: anterior próxima al esternón (región 1), lateral izquierda próxima al ápice del corazón (región 2), posterior (región 3), lateral derecha próxima al paso de la vena cava inferior (región 4) y central (región 5). El promedio de los diámetros latero-lateral y antero-posterior del pericardio fueron de 103,3 +/- 6,7 y 66,0 +/- 2,3 mm, respectivamente y del diafragma de 309,4 +/- 27,4 y 152,5 +/- 24,9 mm, respectivamente. El área del diafragma fue en promedio de 37. 260 +/- 2.324 mm2. El área de la base del pericardio sobre el diafragma fue de 6.042 +/- 367 mm2. El espesor del diafragma fue en promedio: parte derecha, 2,42 +/- 0,34 mm; parte izquierda, 2,38 +/- 0,71 mm y la parte anterior, 2,52 +/- 0,66 mm. El promedio del espesor del pericardio separado del diafragma fue de 0,26 +/- 0,02 mm. En la región 2 ambas estructuras fueron separadas con facilidad en 47,2 mm; en la región 5 ambas estructuras se encuentran fusionadas. Los resultados obtenidos en este trabajo complementarán los conocimientos morfológicos sobre el pericardio fibroso y sus relaciones con el diafragma.

The pericardium is a fibrous and serous membrane that surround the heart and the juxta- cardiac portion of the great vessels. We studied the pericardium and diaphragm and we recorded different measurements, relations and connection between both. We dissected 142 mediastinal regions from 10 percent formaldehyde ¡ fixed or fresh individual cadavers, Brazilian adults, of both sexes, from 18-70 years of age. For the histology study from both structures were sectioned five fragments of different regions: anterior, next to sternum (region 1), left lateral, next to heart apex (region 2), posterior (region 3), right lateral, next to course of inferior vena cava (region 4) and central(region 5). The average of transversal and anterior-posterior diameters of pericardium were 103.3 +/- 6.7 mm and 66.0 +/- 2.3 mm, respectively; the same diameters of diaphragm were 309.4 +/- 27.4 mm and 152.5 +/- 24.9 mm, respectively. The diaphragm area was 37,260 +/- 2,324 mm² and the area of pericardium base over the diaphragm was 6,042 +/- 367 mm² . The thickness of diaphragm was 2.42 +/- 0.34 mm in right part, 2.38 +/- 0.71 mm in left part and 2.52 +/- 0.66 mm in anterior part. The thickness of pericardium was 0.26 +/- 0.02 mm. In region 2 both structures were easily separated in 47.2 mm; in the region 4 both structures are fused. The results of this study will complement the morphologic knowledges about fibrous pericardium and its relationships with the diaphragm.

Regional histomorphometry of the hepatic inferior vena cava; a possible sphincteric mechanism / Histomorfometría regional de la vena cava inferior hepática; un posible mecanismo de esfínter

This study was aimed at identifying the changes in diameter and structural composition of the Hepatic Inferior Vena Cava in its infrahepatic, intrahepatic and suprahepatic portions. Eighty adult liver specimens from the Chiromo and Nairobi City mortuaries were used for morphometry, while twenty of them were processed for light microscopy. A constriction was noted in the mid-portion of the HIVC, while structurally; the intrahepatic portion had thicker fibromuscular adventitia. It is plausible that these are sphincteric apparatus to prevent backflow of blood in the Hepatic Inferior Vena Cava.

Este estudio tiene por objetivo identificar los cambios en el diámetro y la composición estructural de la vena cava inferior hepática en sus porciones infrahepática, intrahepática y suprahepática. Ochenta hígados de especímenes adultos de los depósitos de cadáveres de la ciudad de Nairobi y Chiromo fueron usadas para morfometría, mientras que veinte de ellos fueron procesados para microscopía de luz. Se observó una constricción en el medio de la HIVC, mientras que estructuralmente, la porción intrahepática había una gruesa adventicia fibromuscular. Es posible que este sea un aparato esfinteriano para evitar el reflujo de sangre en la vena cava inferior hepática.

Regional differences in veins wall viscosity, compliance. energetics and damping: analysis of the pressure-diameter relationship during cyclical overloads

Background: The characterization of the dynamic process of veins walls is essential to understand venous functioning under normal and pathological conditions. However, little work has been done on dynamic venous properties. Aim: To characterize vein compliance (C), viscosity (η), peak-strain (W St) and dissipated (W D) energy, damping (ξ), and their regional differences in order to evalúate their role in venous functioning during volume-pressure overloads. Methods: In a mock circulation, pressure (P) and diameter (D) of different veins (anterior cava, jugular and femoral; from 7 sheep), were registered during cyclical volume-pressure pulses. From the P-D relationship, C, W St and ξ (at low and high P-D leveis), η and W D were calculated. Resulls: For each vein there were P-dependent differences in biomechanical, energetics, and damping capability. There were regional-differences in C, η), W St and W D (p<0.05), but not in ξ. Conclusión: The regional-dependent differences in dynamics and energetics, and regional-similitude in damping could be important to ensure venous functioning during acute overloads. The lower C and higher W St and W D found in back-limb veins (femoral), commonly submitted to high volume-pressure loads (i.e. during walking), could be considered relevant to ensure adequate venous system functionality and venous wall protection simultaneously.

Gross anatomy of the retrohepatic segment of the inferior vena cava in northwest Indians.

BACKGROUND AND OBJECTIVES: Information regarding the size and position of the ostia of veins opening into the retrohepatic segment of inferior vena cava (HIVC) in northwest Indians is not available. Knowledge of gross anatomy of this segment is of importance in cases of segmental resection of the liver involving the groove for inferior vena cava (IVC) and when performing selective hepatic venography. We carried out this study to provide information on gross anatomy of HIVC in northwest Indians. METHODS: Livers were obtained from 500 adult autopsy subjects. The HIVC was opened posteriorly by a vertical cut and its circumference at the upper and lower cut ends was measured. To study the position of the ostia of the hepatic veins, HIVC was divided transversely into upper, middle and lower thirds. The anterior and anterolateral walls of HIVC were also divided into four equal parts longitudinally. The venous ostia were classified according to the size of their openings. In addition, in 100 livers the openings were injected with a 20 per cent solution of cellulose acetate butyrate (CAB) in acetone and veins were dissected. RESULTS: The HIVC extended upwards and to the left either obliquely (66.4%) or by describing a gentle curve (33.6%) in its upper half or upper third. Its average length was about 71 mm. Mean diameter at the upper cut end was about 19 mm. The posterior aspect of the upper half or upper one third of HIVC was covered by an extension of the caudate lobe completely (4%) or incompletely (7.4%). The ostia of the left, middle and right hepatic veins were large (>10 mm) and were located in the upper third segment of HIVC. In 87 per cent of specimens the left and middle hepatic veins had a common opening on the left anterior area. The ostium of the right hepatic vein was present in the right anterior area. INTERPRETATION AND CONCLUSION: In conclusion, our study provided gross measurements of HIVC in northwest Indians. A knowledge of the anatomy of HIVC and hepatic venous ostia will help the clinician interventional operator in planning the treatment by choosing a balloon of correct size and at correct site. The measurements helps in determining the fall in portal pressure with pharmacotherapy given for the prevention of variceal bleed.

Estudo da resposta tissular à endoprótese recoberta de jugular bovina em veia cava inferior de suínos / Bovine jugular covered stent-grafit implanted in swine inferior vena cava - a study of tissue response

Objetivo: avaliar a resposta tissular a uma endoprótese, com cobertura biológica, implantada em veia cava inferior de suínos. Métodos: Desenvolvemos uma endoprótese auto-expansível, revestida com um segmento de jugular bovina, conservada por processo L-hydro e saturada em um stent de aço inoxidável 316L. O dispositivo introdutor utilizado foi a bainha de liberação da endoprótese aórtica Taheri-Leonhardt (Flórida, EUA). Foram implantadas endopróteses em 10 suínos, todas na veia cava infra-renal. Os animais foram submetidos à flebografia peroperatória. À necropsia, após 2 meses, cada endoprótese foi retirada em bloco e analisada macroscopicamente, visando a avaliação da perviedade, aderência aos tecidos vizinhos e incorporação à parede venosa; e, histopatologicamente, visando a resposta histológica ao enxerto. Resultados: Na análise macroscópica, todas as endopróteses encontravam-se pérvias e totalmente incorporadas à parede venosa, porém seis apresentavam trabeculações grosseiras no seu interior e quatro algum grau de fibros perivascular. Três animais desenvolveram linfocele, uma retroperitonial e as outras na parede abdominal...

A rare Lymphatico-Venous communication associated with duplication of thoracic duct

RESUMEN: Una inusual presentación de duplicación del conducto torácico con una rara comunicación linfático-venosa, fue encontrada durante una disección de rutina, por estudiantes de pregrado. El conducto torácico se encuentra duplicado a nivel de la vértebra T12. Normalmente el conducto torácico se abre en la unión de la venas yugular interna izquierda y subclavia izquierda. En el lado derecho del cuello, el conducto linfático derecho recibe la linfa de la parte derecha de la cabeza y del cuello, del miembro superior derecho y lado derecho del tórax. El conducto torácico duplicado en el lado izquierdo se abrió directamente en la vena cava inferior. Este caso es discutido con respecto a su desarrollo, incidencia y significación clínica.

Surgical anatomy of retrohepatic inferior vena cava and hepatic veins: a quantitative assessment.

BACKGROUND: Accurate knowledge of the surgical anatomy of the retrohepatic inferior vena cava (IVC) and hepatic veins is necessary for hepatic surgery. METHODS: Lengths of different segments of retrohepatic IVC and their diameters, and prevalence of various types of ramification and lengths of different hepatic veins, were noted in 100 disease-free human livers during autopsy. RESULTS: The mean lengths of the IVC from entry into atrium to diaphragmatic hiatus, from the hiatus to the upper margin of right hepatic vein, between the upper margins of the right hepatic vein and the right suprarenal vein, from right suprarenal vein to the lowermost dorsal hepatic vein, and from the lower-most dorsal hepatic vein to the right renal vein were 29.1 mm, 8.6 mm, 40.6 mm, 28.6 mm and 33.7 mm, respectively. The mean diameter of IVC at the diaphragmatic level was 30.1 mm. The commonest ramification pattern of the hepatic veins was type I (82%) for the right hepatic vein, type II (63%) for the middle and left hepatic veins, and type II (55%) for the caudate veins. In 96% of cases the middle and left hepatic veins formed a common trunk. In a majority of cases, the diameters of the right and left hepatic veins were between 7 mm and 12 mm. No gender differences were found. CONCLUSION: This study provides an anatomical perspective for various hepatic surgical techniques.

Lesiones de vena cava inferior infrarrenal. Experiencia en el servicio de cirugía IV, Hospital Dr. Miguel Pérez Carreño / Inferior cava injury infrarenal experence in the service of surgery IV Hospital Dr. Miguel Pérez Carreño

LA vena Cava inferior representa uno de los vasos abdominales que se lesiona con frecuencia en heridas penetrantes de abdomen. Presentamos 14 casos de lesiones de vena cava inferior infrarrenal en pacientes operados en el lapso enero 1993- octubre 1994. Todas las lesiones se presentaron en hombres a consecuencia de heridas por arma de fuego, fue necesaria la ligadura simple en el 78,5 por ciento y rafia en el 21 por ciento de los casos. La mortalidad fue del 21,5 por ciento

Estudo morfológico da transição cavo-atrial inferior no homem: consideraçöes morfo-funcionais / Morphologic study of transition of the inferior cavo-atrial in man: morphofunctional considerations

Objetivo - Analisar a presença, a disposiçäo espacial e a inter-relaçäo dos elementos fibrosos integrantes da transiçäo entre a veia cava inferior e o átrio direito, com vistas a possíveis interpretaçöes morfo-funcionais. Métodos - Vinte cadáveres, de ambos os sexos, com idades variando entre 20 e 40 anos. As peças, devidamente conservadas, foram analisadas macro e microscopicamente. Foram retirados,fragmentos da transiçäo cavo-atrial inferior e analisados ao estereomicroscópico sob epiluminaçäo. Resultados - A parede anteior da veia cava inferior sempre apresenta válvula e recebe fibras musculares cardíacas de trípice procedência e essas fibras ultrapassam a válvula e se dirigem à túnica íntima da veia. Na parede posterior, as fibras musculares cardíacas procedem da crista terminalis e do septo inter-atrial. Na transiçäo, os feixes musculares lisos se apresentam oblíquos e circulares e os feixes elásticos se continuam da veia para o átrio direito. Conclusäo - Como a disposiçäo dos feixes musculares cardíacos na transiçäo apresenta direçäo predominantemente circular e ainda, os feixes musculares lisos da veia cava inferior também apresentam essa direçäo, pode-se admitir que, ao ocorrer a sístole atrial, esses feixes musculares obliterariam a transiçäo cavo-atrial, impedindo o refluxo venoso, auxiliando portanto, a válvula da veia cava inferior

Purpose - Analysis the fibrous elements of the transiction between the inferior vena cava and right atrium Methods - Twenty adult (20-40 ys) were used. Properly preserved samples were analysed macro and microscopicaly. Fragments were excised from the inferior cavo-atrial transiction and analysed under stereomicroscopic. Results - The inferior vena cava valve was disposed at the wall of the vein. Insertions of striated muscular cardiac fibers bundles are seen at the anterior wall of inferior vena cava. These muscular bundles are directed towards the intima of the vein. There were at the venous posterior wall insertions of the cardiac muscular bundles, originated from the crista terminalis andirom the interatrial septum, these bandles show an orientation predominantly oblique, with tendency to become circular. At the transiction level, the bundles of smooth muscular fibers of the inferior vena cava, presented an oblique disposition, becoming predominantly circular. Conclusion - As the disposition of muscular cardiac fibers presents a predominantly circular direction and, the bundles of smooth mascular fibers of the inferior vena cava present the same direction, we could postulate that, when the atrial systole occurs, these muscular bundles would obliterate the cavo-atrial transiction, preventing, this way, the venous reflux

Anatomia aplicada do segmento supra-renal da veia cava inferior / Applied anatomy of the suprarenal segment of inferior vena cava

O autor organiza a anatomia da veia cava inferior (V.C.I.) de forma anátomo-topográfica a partir de uma revisão bibliográfica Este trabalho aborda de forma descritiva, analítica e sistemática, os componentes do segmento supra-renal (SSR) da V.C.I. abdominal a partir de estudos e dos resultados obtidos de 37 (trinta e sete) dissecções anatômicas da V.C.I. abdominal. O seu comprimento varia de 10,1 a 12,0cm na maioria das peças estudadas. Os seios venosos renocava e hepatocava foram confirmados. A passagem da V.C.I. na face diafragmática do fígado é em forma de sulco em 97,3% das peças, e em forma de túnel em 27,2% das peças. A veia supra-renal direita é única na maioria dos casos, conforme demonstra a literatura pesquisada e deságua no quadrante postero-lateral direito, distribuída nas 03 (tr~es) posições: lateral direita em 43,25% das peças, póstero-lateral em 43,25% e 13,5% na posição posterior do vaso. Na porção retro-hepática do SSR desemboca uma veia hepática direita (V.H.D.), uma veia hepática esquerda (V.H.E.) e uma veia hepática intermédia (V.H.I.), sendo que essa última junta-se com a V.H.E. e desemboca na VCI em forma de tronco, esse foi o modelo encontrado na maioria das peças estudadas, 62,10%. A distância entre a borda superior da VHD e o forame da VC variou entre 0-0,3cm na maioria das peças estudadas (62,10%). O número de orifícios das veias hepáticas menores oscilou entre 01 e 03, na maioria das peças e elas estão presentes com maior frequência nos quadrantes inferior direito e esquerdo da porção retro-hepática do SSR. As veias hepáticas menores provém do lobo caudado na maioria das peças estudadas, (612,10%)ou dos lobos caudado e direito (38% das peças). A veia frênica inferior direita (V.F.I.D.) desemboca em 100% das peças na V.C.I. abdominal, o ramo transverso da veia frênica inferior esquerda (V.F.I.E.) desemboca em 16,2% das peças na V.H.E. e, em 83,88% ela desemboca diretamente na V.C.I. abdominal.

Veia cava inferior dupla; apresentaçäo de um caso / Doubled inferior vena cava; presentation of a case

Relato de um caso de veia cava inferior dupla, em nível lombar, descrito em cadáver adulto do sexo masculino