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Methods@#The electronic databases MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, and Scopus were searched for relevant articles comparing the outcomes of SB-ACLR versus DB-ACLR that were published until November 2019. @*Results@#Seventeen biomechanical studies were included. The anterior laxity measured using the anterior drawer test showed significantly better results in DB-ACLR when compared with SB-ACLR. In addition, outcomes of the anterior tibial translation test under a simulated pivot shift presented with better results at low flexion and 30° in DB-ACLR, compared with SB-ACLR. However, there were no significant biomechanical differences between the groups in internal rotation. @*Conclusions@#The present study demonstrated that both techniques for ACLR are associated with restoration of normal knee kinematics. DB-ACLR is superior to SB-ACLR in terms of restoration of anteroposterior stability.However, which technique yields better improvement in internal rotation laxity, and internal rotation laxity under a simulated pivot shift at a specific angle, remains unclear.Level of evidence: This is a level II meta-analysis.
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PURPOSE: Anterior cruciate ligament (ACL) injury is one of the most common injuries that occur in the knee, and ACL reconstruction (ACLR) is commonly performed for preventing aggravation of degenerative changes and restoring of knee stability in young, athletic patients. This metaanalysis has a purpose of evaluating the clinical and arthrometrical outcomes of ACLR in a group of middle age patients (40 years and older) and comparing with patients under 40 years of age. METHODS: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, Web of Science, and SCOPUS electronic databases were searched for relevant articles comparing the outcomes of ACLR between younger and older than 40 years of age until December 2016. Data searching, extraction, analysis, and quality assessment were performed based on the Cochrane Collaboration guidelines. Clinical outcomes were evaluated and compared between groups. The results were presented as mean difference for continuous outcomes with 95% confidence intervals whereas risk ratio for binary outcomes. RESULTS: Seven studies were included in the meta-analysis. Based on International Knee Documentation Committee classification, side-to-side difference, Tegner activity score, Lysholm knee score, there were no significant clinical and mechanical differences between the groups. CONCLUSIONS: This meta-analysis confirmed that after ACLR, middle age (>40 years) and young age (<40 years) patients did not present with significant difference in clinical and arthrometric results.
Subject(s)
Humans , Middle Aged , Anterior Cruciate Ligament Reconstruction , Anterior Cruciate Ligament , Classification , Cooperative Behavior , Knee , Lysholm Knee Score , Odds Ratio , SportsABSTRACT
PURPOSE: Upper extremity musculoskeletal disorders (UEMDs), such as rotator cuff tear, epicondylitis, and hand osteoarthritis, have a negative impact on quality of life (QOL). In this study, we evaluated the prevalence of rotator cuff tear, lateral and medial epicondylitis, and hand osteoarthritis in the dominant side and the impact of these UEMDs on the disabilities of the arm, shoulder, and hand (DASH) outcome measure, which assesses upper extremity-related QOL. MATERIALS AND METHODS: In 2013–2015, 987 participants from rural areas completed a questionnaire and underwent physical examinations, laboratory tests, simple radiographic evaluations of bilateral upper extremities, and magnetic resonance imaging studies of bilateral shoulders. Based on data from these participants, researchers evaluated DASH and performed a functional assessment of each region of the dominant side and related UEMDs. RESULTS: The prevalences of epicondylitis, rotator cuff tear, and hand osteoarthritis were 33.7%, 53.4%, and 44.6%, respectively. Univariate regression analysis results revealed that epicondylitis, epicondylitis+rotator cuff tear, epicondylitis+hand osteoarthritis, and epicondylitis+rotator cuff tear+hand osteoarthritis were significantly associated with DASH score. Multiple regression analysis, including DASH, UEMD, and regional functional assessments, showed that only epicondylitis and epicondylitis+rotator cuff tear were associated with DASH score. CONCLUSION: Epicondylitis significantly affected QOL, while other UEMDs, such as hand osteoarthritis and rotator cuff tear, had no significant impact. When a patient's QOL is affected by a UEMD, there is an increased possibility of the simultaneous presence of other UEMDs.
Subject(s)
Arm , Hand , Magnetic Resonance Imaging , Osteoarthritis , Outcome Assessment, Health Care , Physical Examination , Prevalence , Quality of Life , Rotator Cuff , Shoulder , Tears , Upper ExtremityABSTRACT
Due to an oversight of the editorial team, the original version of this article contained an error in the list of authors.
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We investigated whether betulin affects the gene expression, secretion and proteolytic activity of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as in vivo production of MMP-3 in the rat knee joint to evaluate the potential chondroprotective effect of betulin. Rabbit articular chondrocytes were cultured and reverse transcription-polymerase chain reaction (RT-PCR) was used to measure interleukin-1β (IL-1β)-induced gene expression of MMP-3, MMP-1, MMP-13, a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4), ADAMTS-5 and type II collagen. Effect of betulin on IL-1β-induced secretion and proteolytic activity of MMP-3 was investigated using western blot analysis and casein zymography, respectively. Effect of betulin on MMP-3 protein production was also examined in vivo. The results were as follows: (1) betulin inhibited the gene expression of MMP-3, MMP-1, MMP-13, ADAMTS-4, and ADAMTS-5, but increased the gene expression of type II collagen; (2) betulin inhibited the secretion and proteolytic activity of MMP-3; (3) betulin suppressed the production of MMP-3 protein in vivo. These results suggest that betulin can regulate the gene expression, secretion, and proteolytic activity of MMP-3, by directly acting on articular chondrocytes.
Subject(s)
Animals , Rats , Blotting, Western , Caseins , Chondrocytes , Collagen Type II , Gene Expression , Knee Joint , Knee , Osteoarthritis , ThrombospondinsABSTRACT
PURPOSE: The object of this study was to evaluate entrance angle effects on femoral tunnel length and cartilage damage during anteromedial portal drilling using three-dimensional computer simulation. MATERIALS AND METHODS: Data was obtained from an anatomic study performed using 16 cadaveric knees. The anterior cruciate ligament femoral insertion was dissected and the knees were scanned by computer tomography. Tunnels with different of three-dimensional entrance angles were identified using a computer simulation. The effects of different entrance angles on the femoral tunnel length and medial femoral cartilage damage were evaluated. Specifically, tunnel length and distance from the medial femoral condyle to a virtual cylinder of the femoral tunnel were measured. RESULTS: In tunnels drilled at a coronal angle of 45degrees, an axial angle of 45degrees, and a sagittal angle of 45degrees, the mean femoral tunnel length was 39.5+/-3.7 mm and the distance between the virtual cylinder of the femoral tunnel and the medial femoral condyle was 9.4+/-2.6 mm. The tunnel length at a coronal angle of 30degrees, an axial angle of 60degrees, and a sagittal angle of 45degrees, was 34.0+/-2.9 mm and the distance between the virtual cylinder of the tunnel and the medial femoral condyle was 0.7+/-1.3 mm, which was significantly shorter than the standard angle (p<0.001). CONCLUSION: Extremely low and high entrance angles in both of axial plane and coronal plane produced inappropriate tunnel angles, lengths and higher incidence of cartilage damage. We recommend that angles in proximity to standard angles be chosen during femoral tunnel drilling through the anteromedial portal.
Subject(s)
Aged , Female , Humans , Male , Middle Aged , Anterior Cruciate Ligament/surgery , Anterior Cruciate Ligament Reconstruction/instrumentation , Cadaver , Computer Simulation , Femur/anatomy & histology , Imaging, Three-Dimensional , Knee Joint/diagnostic imaging , Osteotomy/methods , Outcome and Process Assessment, Health Care , Patient Positioning , Surgical Instruments , Tomography, X-Ray ComputedABSTRACT
PURPOSE: The aim of this study was to evaluate the correlation between the 3-dimensional (D) notch volume and the 2D notch width and notch shape as measured on magnetic resonance imaging (MRI), between subjects with anterior cruciate ligament (ACL) injury and those without ACL injury. MATERIALS AND METHODS: Knee MRI images were taken from 72 subjects with ACL injury and 80 subjects without ACL injury (January 2007 to January 2012; Gyeongsang National University Hospital, Jinju, Korea). We measured 3D notch volume and 2D notch width and notch shape. The measured values from MRI figures between ACL-injured subjects and non-ACL-injured subjects were compared and analyzed. These measurements (notch width, notch ratio) were correlated to notch volume. Both intra-observer reliability and inter-observer reliability were calculated. RESULTS: Notch width differed significantly between ACL injured subjects and non-injured subjects (p<0.001), while no significant differences in notch volume and notch shape were observed between the groups (male: p=0.43, female: p=0.22). CONCLUSION: The results of this study might suggest that certain 2D measurements (notch width) of the notch could be better than notch volume for prediction of ACL rupture risk.
Subject(s)
Female , Humans , Anterior Cruciate Ligament , Knee , Magnetic Resonance Imaging , RuptureABSTRACT
The purposes of this study were basic data collection and evaluation of the risk factors regarding rowing injuries through an epidemiologic study. We performed a questionnaire survey from rowers who participated in the 91th Annual Sports Festival in Jinju, Gyeongnam, in October 2010. 145 rowers (male: 84, female: 61) responded to the survey. The t-test was used for comparisons for the type of injury, age, and gender. The multiple linear regression analysis and the logistic regression analysis was used for the evaluation of risk factors. Overall, 100 (69.0%) rowers had a history of injury. The incidence of overuse injuries was significantly higher than the incidence of traumatic injuries (2.07+/-2.59/rower vs. 1.46+/-2.08/rower, p=0.027). The incidence of injuries for the adult group was significantly higher than those in the youth group (4.42+/-4.45/rower vs. 2.61+/-3.63/rower, p=0.008). There was no significant difference between males and females (3.85+/-4.33/rower vs. 3.08+/-3.87/rower, p=0.275). Also, the incidence of cross-training related injury was significantly higher in traumatic injuries rather than in overuse injuries (0.92+/-1.54/rower vs. 0.5+/-1.07/rower, p=0.008). In addition, rowing injuries were more related with overuse injuries. Risk factors regarding overall rowing injuries were training time, and training using stairs. Traumatic injuries were related with diverse cross-training and time spent cross-training. Therefore, in order to reduce the incidence of rowing injuries, time and the number of cross-training sessions should be reduced. Moreover, highly risky training such as using stairs should be replaced with other low risk training methods.
Subject(s)
Adolescent , Adult , Female , Humans , Male , Athletes , Cumulative Trauma Disorders , Data Collection , Epidemiologic Studies , Holidays , Incidence , Linear Models , Logistic Models , Surveys and Questionnaires , Risk Factors , SportsABSTRACT
Intraosseous epidermal inclusion cyst is a rare benign, cystic lesion. It is thought to result from traumatic implantation of epidermal elements into bone. Radiologic findings of intraosseous epidermal inclusion cysts are well-defined, lytic lesions. It is difficult to diagnose intraosseous epidermal inclusion cyst without pathologic diagnosis. We experienced a 43-year-old man with a history of trauma followed by painless expansion of his left thumb. Radiographs demonstrated a severe expansile, ill-defined lytic lesion with cortical destruction in the distal phalanx of left thumb, mimicking neoplastic bone lesion or infectious lesion. An intraosseous epidermal inclusion cyst was confirmed by pathologic diagnosis, which was lined by stratified squamous epithelium, containing keratinized cellular debris.
Subject(s)
Adult , Humans , Epithelium , Keratins , ThumbABSTRACT
Both os trigonum syndrome and osteochondral lesion of talus (OLT) are common causes of ankle pain and usually affect ballet dancers or athletes. Lateral osteochondral lesions, which usually result from traumatic event, are mostly located anterolateral talar dome but rare central or posterolateral. Moreover, there are technical difficulties such as position of patient or additional posterior portal to address posterolateral lesion by arthroscopy. Meanwhile, treatment of os trigonum syndrome using arthroscopic approach has been reported in many literatures recently. However, it has not been reported to diagnose both os trigonum syndrome and posterolateral OLT together and treat arthroscopically at one stage. The authors report a case of male patient who was diagnosed as os trigonum syndrome with posterolateral OLT and treated simultaneously by hindfoot arthroscopy. Symptom was improved immediately after the operation, and radiological findings at postoperative 16 months verified remarkable healing.
Subject(s)
Animals , Humans , Male , Ankle , Arthroscopy , Athletes , TalusABSTRACT
PURPOSE: Poland syndrome is rare disease which is characterized by absence of unilateral pertoralis major muscle accompanied by ipsilateral syndactyly or brachydactyly, which was described first by Alfred Poland in 1841. MATERIALS AND METHODS: We performed the physical examination, laboratory test and radiologic evaluation to 18 year old male, who complaint asymmetry of right anterior chest. RESULTS: We diagnosed the Poland syndrome due to absence of right pectoralis major muscle and brachydactyly of right hand. CONCLUSION: Current authors report a patient who had hypopalsia of pectoralis muscles, which needed differential diagnosis with pectoralis major rupture.