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1.
Article in Chinese | WPRIM | ID: wpr-485289

ABSTRACT

Objective:To investigate the normal sonographic anatomic characteristics of the pectoralis major and the clinical value of ultrasound in diagnosing the extent and location of the pectoralis major tears.Methods:High frequency transducer was used in scanning the pectoralis major.The ultrasono-graphic images of 40 normal pectoralis major were obtained from 20 healthy volunteers with both sides. Longitudinal and transversal views were performed and stored.The distal tendon was identified in the transverse plane coursing superficially to the long head of the biceps brachii tendon inferior to the level of the subscapularis tendon.Eighteen cases of pectoralis major tears were analyzed retrospectively,with MRI,surgical and ultrasound follow-up results correlation respectively.Results:High-frequency ultra-sound could clearly show the anatomic orientation of the normal pectoralis major.The fibers converge was like a fan into three laminae that twisted upon each other at 90°before coalescing into a single tendon of insertion.In the study,1 8 patients of pectoralis major muscle tears [average age:(37.2 ±1 5.6)years] sustained injuries during weightlifting,basketball and impact.Three of the eighteen patients had MRI re-sults;nine had surgical correlation;six were followed by ultrasound.Eleven were injured on the left side,and 7 on the right side.Seven were involved in the distal tendon (1 in sternal head,2 in clavicular head,4 in both sternal and clavicular head),five were involved the musculotendinous junction,6 were involved muscle belly.Twelve cases were partial-thickness petoralis major tears(4 in the distal tendon, four in the muscle tendon junction,4 in the muscle belly),with the partial fiber intact,echogenicity de-creased and the internal structure disordered;6 cases (3 in the distal tendon,1 in the muscle tendon junction,2 in pectoralis major muscle belly)were completely disrupted,with fiber fracture and retrac-tion,accompanied with or without hematoma formation.Conclusion:High-frequency ultrasound can clearly show the anatomic structure of the pectoralis major.Ultrasonography can diagnose the pectoralis major tears with the extent and location of injuries,and can be used to help the clinical treatment.

2.
Article in Chinese | WPRIM | ID: wpr-492573

ABSTRACT

[Summary] This paper reported a patient suffering from hemorrhage after percutaneous liver biopsy treated by contrast enhanced ultrasound-guided percutaneous injection of thrombin in June 2015.Firstly,we performed contrast-enhanced ultrasound examination to find the position of active bleeding.And then,percutaneous injection of thrombin was performed under the guidance of ultrasonography.The active bleeding was stopped successfully.

3.
Article in Chinese | WPRIM | ID: wpr-494944

ABSTRACT

Objective By analyzing the correlation between Doppler spectrum of extracranial cerebral vessels ECV and intracranial arterial stenosis IAS to identify the value of hemodynamic change of ECV in predicting IAS Methods One hundred and four patients with moderate to severe IAS or intracranial arterial occlusion were enrolled in the case group while 32 patients without obvious cerebrovascular disease in the same period were enrolled in the control group Ultrasound examinations of ECV were performed for all patients the hemodynamic parameters of bilateral common carotid artery CCA internal carotid artery ICA and vertebral artery VA were recorded and compared between case and control group Results Compared with control group the ECV of patients with IAS had lower velocity and higher resistance index RI Of all the parameters end diastolic velocity EDV of ICA and EDV of VA were most accurate in predicting IAS with best cut off value of 21 3 cm/s 9 6 cm/s and accuracy of 76 1 % 81 0% respectively Conclusions The ECV of IAS patients tend to have lower velocity and higher RI Analysis of hemodynamic parameters of ECV might be useful in predicting IAS.

4.
Article in Chinese | WPRIM | ID: wpr-452217

ABSTRACT

BACKGROUND: Numerous evidence has demonstrated that the magnesium aloy with excelent mechanical properties can degradein vivo, and can be used as vascular stent materials, bone fixation materials, porous materials for bone repair. But it is not reported in the biliary stent. OBJECTIVE:To observe the degradation procedures and evaluate the changes of mechanical characteristics of biliary stents made of magnesium aloy (AZ 31B) in human bilein vitro. METHODS:The baloon-expandable biliary stents were made of magnesium aloy with laser sculpture. Then, 15 stents treated with micro-arc oxidation on the surface served as experimental group and another 15 stents without micro-arc oxidation as control group. A dynamic numerical simulation system was establishedin vitro to simulate the internal environment of human biliary tract. Al of the biliary stents were placed into this system. Their shapes were observed, and their qualities and radical forces were measured every 20 days. At the same time, their surfaces were scanned by scanning electron microscope. RESULTS AND CONCLUSION:(1) The degradation speeds of the stents in the experimental group were obviously slower than those in the control group. The fracture of the connecting rods in control group and experimental group appeared 20 days and 40 days later, respectively. The peak time of degradation in the control group and experimental group were 30 days and 50 days, respectively. The stents were fuly biodegraded within 70 days in the control group while within 90 days in the experimental group. With time, the stent surface became more rough, and the density, area and depth of etch pits were al increased in the two groups. At the same stage, the degradation speed of the control group was more rapid than that in the experimental group. (2) The qualities and radical forces of the stents were gradualy reduced with time in both groups. However, the degradation speed of stents in the experimental group was much slower than that in the control group. In summary, the degradation speed of the biliary stents made of magnesium aloy treated with micro-arc oxidation is appropriate and can meet the clinical requirement for the degradation time of biliary stents. This novel material could potentialy be used for the preparation of biliary stents.

5.
Article in Chinese | WPRIM | ID: wpr-432980

ABSTRACT

Objective To fabricate an ultrasound/fluorescence bi-modal contrast agent by encapsulating fluorescent quantum dots into polymeric ultrasound contrast agent microbubbles.Methods Polylactic acid (PLA,500 mg),(1R)-(+)-camphor (50 mg) and CdSe/ZnS quantum dots (0.5 ml,2.3 μmol/L)were dissolved or dispersed in dichloromethane (10 ml) to form in an organic phase.Ammonium carbonate solution and poly (vinyl alcohol) solution were employed as the internal and external water phase,respectively.The fluorescent microbubbles were generated using double emulsion solvent evaporation and lyophilization methods.The morphology and illumination were characterized by scanning electron microscopy (SEM) and fluorescence spectrophotometry.Synchronized contrast-enhanced ultrasound and fluorescence imaging was acquired by injecting fluorescent microbubbles into the silicone tube coupled to a self-made ultrasound/fluorescence imaging device.Ultrasound/fluorescence bi-modal in vivo imaging was acquired on the kidney of New Zealand rabbits and suckling mice.Results The fluorescent microbubbles were hollow spheres with an averaged diameter of (1.62 ± 1.47) μm.More than 99% of these microbubbles were less than 8 μm in diameter,which meeted the size criteria for ultrasound contrast agents.The fluorescence emission peak of the microbubbles appeared at 632 nm,indicating that good luminescence properties of quantum dots were maintained.In vitro ultrasound/fluorescence imaging showed no echoic signal when the silicone tube was filled with saline,but there was a strong echo when filled with fluorescent microbubbles.The liquid column with fluorescent microbubbles emitted red luminescence under ultraviolet irradiation.The kidney of the rabbit was remarkably enhanced after the administration of fluorescent microbubbles.Bright fluorescence could be observed at the injection site of the suckling mice via subcutaneous injection.Conclusions A bi-modal but single contrast agent based on polymeric microbubbles has been successfully fabricated for the use of ultrasound and fluorescence imaging.It retains the good characteristics of both echogenicity and fluorescence,which complement each other in case of limitations imposed by uni-modal,single agents.

6.
Article in Chinese | WPRIM | ID: wpr-431115

ABSTRACT

Objective To manufacture magnetic microbubbles with dual-response to ultrasound and magnetic fields.Methods Microbubbles of ultrasound contrast agent (ST68) based on a surfactant were prepared by the acoustic cavitation method.Fe3O4 magnetic nanoparticles with negative charge were synthesized using the polyol procedure.Magnetic microbubbles were generated by depositing polyethylenimine and Fe3O4 magnetic nanoparticles alternately onto the microbubbles using the layer-by-layer self-assembly.In vitro ultrasonography was performed on a silicone tube with/without magnetic microbubbles (3 × 108/ml) by a self-made device to observe the movement of magnetic microbubbles under the effects of magnetic field.In vivo imaging was performed on the kidney of New Zealand rabbits before and after the injection of magnetic microbubbles.Results The Fe3O4 nanoparticles carried a stable negative charge of (-24.6 ± 6.7) mV and more than 98% of the particles were less than 8 μm in diameter,meeting the size requirement of an ultrasound contrast agent for intravenous administration.There was no echoic signal in the silicone tube before injection of magnetic microbubbles,but there were strong echoic signals after injection.After applying a magnetic field,the magnetic microbubbles moved along the direction of the magnetic flux.In vivo ultrasound imaging could not visualize the kidney before injection of magnetic microbubbles,but could remarkably visualize the kidney after injection.Conclusions The magnetic microbubbles exhibit favorable magnetic targeting and ultrasound contrast enhancement characteristics.Such properties may serve as the foundation to study their potential for simultaneous diagnosis and treatment in the future.

7.
Article in Chinese | WPRIM | ID: wpr-425179

ABSTRACT

Objective To evaluate hepatic perfusion assessed by contrast-enhanced ultrasonography (CEUS) for predicting cirrhosis accurately and non-invasively.Methods Forty patients with cirrhosis and twenty-five healthy controls were given CEUS examination,and time-intensity curves were drawn as the regions of interest located in liver parenchyma by using QLAB analyzing soft.The parameters of the two groups as follows:intensity of arterial perfusion (Iap),intensity of total perfusion of liver parenchyma (Ipeak),intensity of portal venous perfusion (Ipp),the ratio of portal venous perfusion and total perfusion (Ipp/Ipeak) were compared by independent-samples t test,and the diagnostic value of parameters were analyzed by receiver operating characteristic (ROC) curve.Resnlts Iap was bigger,while Ipp,Ipp/Ipeak were smaller in patients than that in controls( P <0.001 ).But there was no significant difference on Ipeak between the two groups.When Iap,Ipp,Ipp/Ipeak were used for the diagnosis of cirrhosis,the sensitivity were 67.3 %,92.7%,96.4% and the specificity were 80.0%,96.0%,92.3%,respectively.Conclusions CEUS can reflect the changes of the blood perfusion of cirrhotic liver.CEUS parameters Iap,Ipp,Ipp/Ipeak are significant different between the two groups and can be the non-invasive diagosis parameters of cirrhosis.

8.
Article in Chinese | WPRIM | ID: wpr-423565

ABSTRACT

Objective To investigate the feasibility of non-invasive quantitative evaluation of portal pressure (Pp) by contrast enhanced ultrasonography (CEUS).Methods 18 portal hypertension patients (PTH group) were performed with CEUS within one week before splenectomy and pericardial devascularization,and 20 healthy volunteers as controls were recruited in this study (control group).Hepatic-right kidney sectionwas chosen to calculate the area under curve of portal vein/hepatic artery (Qp/Qa) and the perfusion intensity of portal vein/hepatic artery (Ip/Ia) through time intensity curves (TIC) of liver parenchyma generated from CEUS images.Pp was measured by intra-operative mesenteric vein catheter,and the correlation betweenPp and Qp/Qa,Ip/Ia were analyzed by Pearson correlation test.Results The levels of Qp/Qa and Ip/Ia in the PTH group were 2.28 ± 0.66 and 0.35 ± 0.14 respectively,which were both significantly declined than that in the controlgroup (5.72 ± 3.69 and 1.97 ± 0.17).In the PTH group,the correlation coefficient were-0.747 and-0.617,and the linear regression equations were Y =-83 X + 5.013 andY =-15X + 0.837,which indicated that Qp/Qa and Ip/Ia had significant correlation with Pp.Conclusions CEUS parameters,including Qp/Qa and Ip/Ia,are significantly correlated to Pp in portal hypertension patients,which indicate that CEUS could be a new non-invasive clinical method for evaluating Pp.

9.
Article in Chinese | WPRIM | ID: wpr-423559

ABSTRACT

Objective To investigate the incidence,sonographic appearance of the anatomic variation of carpal tunnel median nerve and its accompanying structures in healthy volunteers and explore the value of this variation in carpal tunnel syndrome.Methods A total of 360 hands of 180 healthy volunteers were included in the study.The full course of the median nerve in the forearm and carpal tunnel was examined with high-frequency ultrasound.The median nerve was first located in cross section at wrist and then with continuous cross-sectional scanning to observe the the full course of the median nerve in the forearm and carpal tunnel with high-frequency ultrasound.Results Anatomic variation of carpal tunnel median nerve and its accompanying structures were observed:① High division median nerve were found in 2 wrists (0.56 %) ;②Bifid median nerve were found in 17 wrists (4.72%) ;③Persistent median artery were found in 22 wrists (6.11%),and 2 wrists (0.56%) were also found accompanied vein.Aanatomic variation of carpal tunnel median nerve accompanied with persistent median artery were observed in 16 wrists (4.44 %).Conclusions High-frequency ultrasound was sensitive to diagnose the anatomic variation of carpal tunnel median nerve and its accompanying structures.Recognition of these variations can help us to make correct diagnosis of carpal tunnel syndrome.

10.
Article in Chinese | WPRIM | ID: wpr-428879

ABSTRACT

The present residents training for ultrasound departments depends mostly on poorlyscheduled rotation and clinical clerkship,with repeated and obsolete subjects in their training.The authors identified these setbacks and such characteristics as complication of ultrasound medicine,complex and variable ultrasonic scan technique,and the high threshold for beginners.In view of this,the authors adopted the tutorial system training mode for cultivating the residents in their medical care,teaching,research and foreign language competencies.A questionnaire survey of 44 residents so trained evaluated outcomes of the mode,with constructive suggestions raised on expansion of the training base,improvement of teachers’competency and reduction of trainees' workload.

11.
Article in Chinese | WPRIM | ID: wpr-385738

ABSTRACT

Objective To discuss the feasibility of non-invasive quantitative evaluation of hepatic fibrosis by contrast-enhanced ultrasonography (CEUS) parameters. Methods CEUS of liver and liver biopsy were performed in 86 patients. CEUS parameters including area under curve of portal vein/hepatic artery(Qp/Qa) ,perfusion intensity of portal vein/hepatic artery(Ip/Ia), decreasing rate of liver parenchyma perfusion (β) and perfusion time of portal vein (Tp) were calculated based on CEUS images. Differences of the four parameters among stages of hepatic fibrosis were analyzed by ANOVA and Spearman rank correlation test was applied to analyze correlation between parameters and hepatic fibrosis stages. Areas under receiver operating characteristic (ROC) curves were calculated to evaluate the diagnostic accuracy of parameters. Results Tp and β had increasing tend while Ip/Ia and Qp/Qa had declining tend from S0 to S4.They were significantly correlated with fibrosis stage( P <0.05=. The areas under ROC curves of Ip/Ia were 0.931 (≥S1) ,0.884(≥S2 ) ,0.820(≥S3 ) and 0.846(S4 ) respectively. The areas under ROC curves of Qp/Qa were 0.914(≥S1),0.813(≥S2),0.845(≥S3) and0.869 (S4) respectively. Conclusions CEUS parameters of liver parenchyma Ip/la, Qp/Qa, Tp and β are related to fibrosis stages. Ip/Ia and Qp/Qa provide a reliable,non-invasive method for evaluating fibrosis stages.

12.
Article in Chinese | WPRIM | ID: wpr-473299

ABSTRACT

Objective To discuss the significance and value of speckle tracking imaging (STI) technique for accurate evaluating different types myocardial systole. Methods Anterior interventricular branches of 11 healthy crossbreed dogs were separated and ligatured to establish acute myocardial infarction models. The short axle radial strain (RS), circumferential strain (CS) of ventricular sinister and long axle longitudinal (LS) of apex of experiment dogs were measured with STI technique before and after myocardial infarction. Results Before myocardial infarction, no statistical difference of RS, CS was detected among sections of left ventricle (P>0.05), and RS was greater than LS (P<0.05). When detector was at the apex of base, LS of middle, apex sections of left ventricle myocardium increased gradually (LS of base section was least and apex section was most) (P<0.05). RS, CS and LS of antetheca, forepart of interventricular septum of middle of left ventricle and antetheca, posterior and forepart septum of apex all became lower after myocardial infarction (P<0.05). Conclusion Strains caused by all types of myocardium action can be accurately evaluated with STI.

13.
Article in Chinese | WPRIM | ID: wpr-471603

ABSTRACT

Objective To observe the relationship between morphology of ciliary body and glaucoma with ultrasound biomicroscopy (UBM). Methods Eighty shallow-anterior chamber patients and 80 normal-anterior chamber patients were enrolled as shallow-anterior chamber group and control group, respectively. All patients were greater than 40 years old. The shallow-anterior chamber group included 28 patients of acute angle-closure glaucoma (AACG subgroup), 26 patients of chronic angle-closure glaucoma (CACG subgroup), and 26 patients of primary angle-closure suspects (PACS subgroup). Both eyes of all patients were checked with UBM, and position of each eye on sagittal and coronal section of superior, nasal, inferior and temporal were recorded. Then ciliary process height (CPH), ciliary process thickness (CPT), ciliary process interval (CPI), ciliary process number (CPN), A angle and α angle were measured. Furthermore, the difference between shallow-anterior chamber group and control group, the difference between AACG, CACG and PACS subgroup were compared, as well as the difference between PACS subgroup and control group, and the correlation between A angle and α angle was analyzed. Results Compared with control group, CPH and CPT of shallow-anterior chamber group increased, while CPI, CPN, A angle and α angle decreased (P<0.05). Except CPH and CPN between CACG and PACS subgroup, there were significant differences of parameters between subgroup of AACG, CACG and PACS (P<0.05). CPH of PACS subgroup increased than those of control group, while CPI, CPN, A angle and α angle decreased (P<0.05). There was positive correlation between A angle and α angle. Conclusion Morphologic parameters of ciliary process may be sensitive indexes which can early screen primary angle-closure glaucoma.

14.
Article in Chinese | WPRIM | ID: wpr-392773

ABSTRACT

Objective To evaluate the basilar artery hemodynamical changes in cervical rotation and ventral flexion by color Doppler flow imaging(CDFI). Methods Basilar artery blood flow were detected during cervical With cervical right lateral,left lateral rotation and ventral flexion, the detection ratio of basilar artery by ultrasound were 89% ,84% ,81% respectively. There were no difference in statistics between the detction ratio of three kinds during cervical flexion,peak systolic velocity(PSV) and end-diastolic velocity(EDV) decreased apparently during left lateral rotation,which did not change during right lateral rotation. No changing was found with resistant index between the three kinds of cervical position. Conclusions The hemodynamic changing of basilar artery during cervical rotation and flexion could be detected by CDFI accurately,which might be useful in clinical study.

15.
Article in Chinese | WPRIM | ID: wpr-399274

ABSTRACT

Objective To measure the thickness of the iliotibial band(ITB)in normal adult volunteers and to evaluate the value of ultrasonography in the diagnosis of ITB injury.Methods Ultrasonography was used to measure the thickness of the ITB in 20 normal adult volunteers,which were compared with the sonographic findings in 11 patients with iliotibial band friction syndrome(ITBFS).Results The thickness of the ITB in normal volunteers was(1.55±0.40)mm at the level of the femoral condyle and(2.05±0.30)mm at the insertions of tibial tubercle(Gerdy's tubercle).There were no significant differences between the right and left sides.In each of 11 patients with ITBFS,there was a more ITB thickness in symptomatic side than that of asymptomatic side(more than 30% in the difference between two sides).The ITB had a area of decreased echoginicity in symptomatic side.The thickened position of ITB were at insertion resion in 6 cases,at the level of femoral condyle in 3 cases and diffuse in 2 cases.Bursa fluid were found in 4 cases.Conclusions Ultrasonography can effectively evaluate the degree and range of ITB injury,and can give important information for clinical theraphy.

16.
Article in Chinese | WPRIM | ID: wpr-401129

ABSTRACT

Objective To investigate the application of real-time gray-scale contrast enhanced ultrasound (CEUS)imaging in the diagnosis of fallopian tube obstruction.Methods Forty-six females with infertility in the period of 3-7 days after menses were inspected by transvaginal CEUS,and the transmission of contrast agents in the fallopian tubes was observed.Then they were inspected by routine iodic X-ray salpingography.Later the value of real-time gray-scale CEUS in diagnosis of fallopian tube was evaluated.Results The sensitivity of CEUS indiagnosis of fallopian tubal unobstruction,obstruction and open without freely was 92.0%,87.1%,36.4%respectively;the specificity was 85.7%,96.7%,93.7%;the accurate was 89.1%,93.5%,84.7%;the Kappa was 0.78,0.85,0.16 with X-ray salpingography.The concordance was 83.7% between CEUS and X-ray salpingography.Conclusions There were no significant difference between CEUS and X-ray salpingography in diagnosis of fallopian tube unobstruction or obstruction,and the former method is safer and more convenient that is suitable to become an valuable method in inspecting of infertility.

17.
Article in Chinese | WPRIM | ID: wpr-595970

ABSTRACT

Objective To elucidate the relationship between mandibular lateral displacement and mandible asymmetry by observing the morphological changes of condylar head and mandible during mandibular lateral displacement in growing rats.Methods Forty-eight male Wistar rats at the age of four weeks were divided at random into experimental and control groups,with 24 rats in each group.A super-hard resin plate was cemented to upper incisors to displace rat mandibles 2 mm to the left during closure(Ipsilateral side).A metal crown was fitted to lower incisors.The rats were killed 2,4,8 or 12 weeks after appliance attachment.The mandible was dissected out and halved.The length and width of condylar head were measured with a caliper.Radiographic films of the mandibles were exposed,and selected measurements were made.Results The length of condylar cartilage on the ipsilateral side was significantly larger than contralateral side in experimental group(P

18.
Article in Chinese | WPRIM | ID: wpr-590089

ABSTRACT

OBJECTIVE To investigate the sterilizing effect of Avagard surgery wasting liquid.METHODS All the staff on operation were divided into two groups at random,each no less than 50 persons.Both groups were sterilized by 4% Avagard surgery washing liquid.In one group,hands and forearms were smeared by 0.5% Avagard fast surgery washing liquid(smearing group),the other group was not smeared by 0.5% Avagard fast surgery washing liquid(no-smearing group).In both groups the samples were derived from fingers and cultured right after sterilization and at intervals of 1h,2h,3h,4h,5h and 6h during operation,and to investigate the sterilization effect.RESULTS The bacteriological detections of both groups in all times showed that the number of colony was0.05).CONCLUSIONS The results of the experiment show that 4% Avagard surgery washing liquid is reliable for its sterilizing effect and easy to use.The duration of antibacterial effect is no less than 6 hours,this method could reduce the cost of the operation and improve the efficiency of work.

19.
Article in Chinese | WPRIM | ID: wpr-540054

ABSTRACT

Objective To compare the distance of left ventricular along long axis measuring under real-time movement and Doppler tissue imaging.Methods Titanium nips were implanted into anterior wall and anterior septum of left ventricule of 7 open-chest canine models.Quantitative study was made on time velocity integral(TVI) of the implanted myocardium and left ventricular long axis in 7 canine models,and 7 patients with replaced metal mitral valve.Digital subtraction angiography was adopted to record the real-time movement of the titanium nips in 7 canine models and the metal valve in 7 patients.And comparison was made between the results.Results The maximum values of displacement measuring with TVI were close to the distance under real-time movement. Conclusions The displacement measuring with TVI can reflect the character of the myocardial displacement truly.

20.
Article in Chinese | WPRIM | ID: wpr-539938

ABSTRACT

Objective To evaluate the feasibility and clinical value of color Doppler flow imaging(CDFI) guided inferior vena caval filter insertion(IVCFI). Methods Thirty-one consecutive patients with unilateral lower extremity deep venous thrombosis were selected for IVCFI. Screening CDFI was performed in all the patients. Locations of renal veins (RV),maximum diameter of the inferior vena cava (IVC),and presence or absence of thrombus were documented. If visualization was adequate,IVCFI was performed under guidance of CDFI. CDFI and abdominal plain film of radiograph were used to document proper deployment,and circumferential engagement of the filter struts in the IVC wall. Also,CDFI was repeated each one month to assess IVC filter migration,thrombus adherent to the filter,and IVC patency. Results CDFI visualization was adequate in thirty-one patients(100%) and the average diameter of IVC was 19.7 mm. Thirty-one VenaTech IVC filters were placed without technical difficulty. No technical complication occurred in all the patients. Follow-up examination showed that no filter uncompleted opening and migration and no IVC thrombus were observed. Seven cases (29%) with embolus trapped by IVC filter were found. There had been no report of pulmonary emboli after IVCFI. Conclusions Placement IVC filter is feasible and safe with CDFI. CDFI-guided IVCFI substantially reduces the procedural cost and avoids the need for radiation exposure and intravenous contrast.

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