ABSTRACT
Acute liver failure (ALF) is commonly used to describe the emergence or development of an acute attack of abnormal liver function. It is a rare but severely life-threatening clinical syndrome that often causes jaundice, coagulopathy and hepatic encephalopathy. Encephalopathy(HE) and multiple organ failure. ALF has a wide range of etiological factors. In the global scope, different regions often show different epidemiological characteristics. With the gradual improvement of specialized diagnosis and intensive care, the prognosis of ALF has improved significantly. The current clinical treatment methods of ALF include etiology treatment, symptomatic supportive treatment, immunotherapy, artificial liver and liver transplantation. This article will summarize the causes of ALF and discuss the latest treatment progresses of ALF.