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A 75-year-old male with a previous history of coronary artery bypass grafting (LITA-LAD, RITA-RA-4PD-14PL) was referred to our hospital for congestive heart failure. Cardiac workup revealed severe ischemic mitral regurgitation which required surgical correction. His preoperative coronary arterial computed tomography demonstrated total occlusion of both orifices of the native coronary arteries, and the complete dependence of his myocardial blood supply on the patent bypass grafts without any evidence of ischemia. Therefore, antegrade cardioplegia could not be applied for cardiac protection during the procedure. Continuous retrograde cardioplegia was planned to be applied in a case where both arterial grafts could be dissected and clamped whereas systemic hyperkalemia and mild hypothermia would be applied in case where the clamp would be impossible. Intraoperatively, both arterial grafts could be dissected and clamped and we performed mitral annuloplasty and tricuspid annuloplasty using continuous retrograde cardioplegia. The patient could be weaned off cardiopulmonary bypass without difficulty, and his postoperative course was uneventful. We conclude that continuous retrograde cardioplegia is a safe and viable option, especially when antegrade cardioplegia is not securely delivered due to an occluded coronary ostia.
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Retrograde myocardial protection plays an important role in cardiac surgery and is widely used. We herein report a rare cardiac surgical case complicated with small coronary sinus ostium in which the cannula of retrograde cardioplegia could not be inserted. A 58 years old man was referred for the treatment of regurgitation and aortic regurgitation. Preoperative ECG gated computed tomography (CT) showed that the orifice of the largest coronary sinus was located in the right atrium with a diameter of only 4 mm with an other 3 smaller orifice in the right atrium and ventricle, which appeared to make it difficult to perform retrograde myocardial protection. The operative finding was consistent with the preoperative CT finding and mitral valve repair and aortic valve replacement were performed using only selective antegrade myocardial protection. We should bear in mind that small coronary ostium exists and preoperative assessment of the size of coronary sinus might be important.
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BACKGROUND@#Pretesting is the key to understanding how the intended audience will react to the message. Resistant reactions affect message processing or can lead to undesirable boomerang effects. The objective of this study was to develop a rating scale for measuring active (reactance) and passive (disengagement) resistance to persuasive health messages.@*METHODS@#Six candidate items (3 items for disengagement and 3 items for reactance) were generated based on literature review. A web-based survey was conducted among Japanese adults aged 25-64 years to verify the reliability and validity of the 6-item resistance scale. Participants were asked to rate one of the advance care planning (ACP) promotion messages. All scale items were scored on a 1-to-5 point Likert scale and they were averaged to produce the resistance score.@*RESULTS@#Explanatory factor analysis revealed a two-factor solution that agreed with the disengagement and reactance domains, respectively. Correlation coefficients between each set of items ranged between 0.30-0.69. Cronbach alpha (0.86) indicated satisfactory internal consistency of the set of items. Confirmatory factor analysis showed a good fit of the two-factor model with CFI = 0.998, SRMR = 0.011, and RMSEA = 0.041. The resistance score showed a moderate positive correlation with negative emotional responses (displeasure γ = 0.55, anger γ = 0.53) and was significantly inversely related to the persuasiveness score (γ = -0.50). Multivariable logistic regression analysis showed that the odds ratio for ACP intention per 1-point increase in the resistance score was 0.47 (95% confidence interval 0.40-0.56) with adjustment for the persuasiveness score.@*CONCLUSION@#The 6-item resistance scale exhibited adequate reliability and validity for measuring audience resistance when applied to the ACP promotion messages in Japanese people. The scale will be useful for pretesting health messages to make them more acceptable to the intended audience.@*TRIAL REGISTRATION@#Not applicable; this is not a report of intervention trial.
Subject(s)
Adult , Humans , Middle Aged , Factor Analysis, Statistical , Intention , Persuasive Communication , Psychometrics , Reproducibility of Results , Surveys and QuestionnairesABSTRACT
Objective: The Sequential Organ Failure Assessment (SOFA) score is a useful tool in defining the clinical conditions and describing the acute morbidity of patient populations with critical illness. This study was performed to assess the usefulness of the SOFA score in predicting the prognosis among cardiac or thoracic aortic postoperative patients. Methods: In total, 123 patients who entered the intensive care unit after a cardiac or thoracic aortic operation from August 2019 to December 2020 were retrospectively investigated. The SOFA score cut-off value from the admission day to postoperative day 3 calculated in the first 60 patients (derivation group) was validated in the latter 63 patients (validation group). Additionally, the Japan SCORE cut-off value calculated in the derivation group was validated in the validation group. Results: The perioperative mortality rate, in-hospital mortality rate and hospital transfer rate were 4.9, 7.3, and 13.2%, respectively. A SOFA score cut-off value of ≥7 for prediction of in-hospital mortality resulted in a sensitivity of 100% and specificity of 81% on postoperative day 2, followed by high sensitivity of 100% and specificity of 95% on postoperative day 3. A SOFA score cut-off value of ≥6 for prediction of hospital transfer resulted in a sensitivity of 57% and a specificity of 67% on postoperative day 2. Conclusion: The SOFA score on postoperative day 2 provides good discriminatory power for in-hospital mortality among cardiac or thoracic aortic postoperative patients. The SOFA scoring system could be useful for predicting short-term prognosis of patients who undergo cardiac or thoracic aortic surgery.
ABSTRACT
We herein report a rare case of unruptured, giant left coronary sinus of Valsalva aneurysm and discuss surgical pitfalls associated with sinus of Valsalva aneurysms. A 63-year-old man was referred to us for clinical diagnosis and surgical treatment of a huge mass in the mediastinum. Enhanced computed tomography (CT) imaging revealed that the mass was a left coronary sinus of Valsalva aneurysm with a diameter of 74×57 mm ; moreover, the left coronary artery originated from the aneurysmal wall. In addition, echocardiography showed moderate aortic regurgitation (AR) caused by dilatation of the aortic annulus. Based on these findings, the Bentall procedure was selected for the Valsalva aneurysm and significant AR. The orifice of the aneurysm was 15×15 mm in size, and the aortic wall of the left coronary sinus was relatively thin. The left main trunk was injured due to severe adhesion between the trunk and the aneurysm ; therefore, vein patch repair was performed with a saphenous vein graft. Since the aortic annulus of the left coronary cusp was fragile, proximal anastomosis of the composite graft to the lesion had to be placed in the fibrous continuity between the aortic and mitral valves. With respect to the proximal anastomosis at the aortic annulus of the left coronary cusp, the suture line was covered with a bovine pericardium patch as there were no remnants of the normal aortic wall. The postoperative course was uneventful, and postoperative CT revealed complete resection of the aneurysm with no evidence of stenosis of the left main trunk.
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We herein report an extremely rare cardiac tumor of lymphatic malformation in 77-year-old man. The computed tomography (CT) demonstrated a mass from the lateral side of the left atrium to the lateral and posterior wall of the left ventricle among intrapericardial adipose tissue involving the left coronary artery. We performed partial resection of the tumor for definitive diagnosis under cardiopulmonary bypass. The histological finding was cardiac lymphatic malformation and was considered to be benign. There was no evidence of the growth of any cardiac tumor during the one-year follow up.
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BACKGROUND@#This study aimed to examine the change in health status of the general public after starting the COVID-19 pandemic and its association with changes in workload and lifestyle.@*METHODS@#A web-based survey was conducted in November 2020, about 9 months after starting the COVID-19 pandemic in Japan, among 8000 Japanese men and women aged 25-64 years. Participants asked for the changes after starting the COVID-19 pandemic in health status, workload, daily life, and health behavior. Ordinal logistic regression was performed to elucidate factors associated with deterioration in general health status.@*RESULTS@#A deterioration in general health status was reported by 17.0% of male and 19.4% of female. There has been a clear shift to sedentary life with decreasing moderate activity and increasing screen time. The multivariate analysis revealed that deteriorated work style, increased burden of housework, decreased moderate activity, increased digital media exposure, and increased body weight were significantly associated with deteriorating health status.@*CONCLUSION@#Both men and women have experienced significant changes in workload and lifestyle since the COVID-19 pandemic started. People should be aware of the risks associated with their recent life changes and take self-care measures to prevent serious health consequences.
Subject(s)
Adult , Female , Humans , Male , Middle Aged , COVID-19/psychology , Health Behavior , Health Status , Japan/epidemiology , Life Style , Multivariate Analysis , SARS-CoV-2 , Surveys and Questionnaires , WorkloadABSTRACT
BACKGROUND@#The persuasive effect of health messages can depend on message features, audience characteristics, and target behaviors. The objective of this study was to compare the responses to persuasive messages encouraging professional help seeking for depression between individuals with and without psychological distress.@*METHODS@#A cross-sectional web-based survey was conducted on Japanese adults aged 35-45 years, who randomly received one of three persuasive messages that aimed to promote help-seeking intentions for depression. The primary message statements were as follows: (1) depression can happen to anyone, (2) depression needs treatment, and (3) depression improves with treatment. Participants rated the messages in terms of comprehensibility, persuasiveness, emotional response, and intended future use. Help-seeking intention for depression was measured using vignette methodology before and after exposure to the messages. Eligible participants who had not received medical treatment for their mental disorders were classified as either distressed (K6 score ≥ 5, N = 824) or non-distressed (K6 score < 5, N = 1133) and analyzed.@*RESULTS@#No significant differences in comprehensibility or persuasiveness scores were observed between the messages, but the distressed group had significantly lower scores than the non-distressed group. Negative emotional responses such as surprise, anger, fear, sadness, guilt, and anxiety were significantly stronger when reading message 2, while a positive emotional response such as happiness was significantly stronger when reading message 3. These emotional responses were more prominent in the distressed than in the non-distressed group. After reading messages 1, 2, and 3, the proportions of participants in the distressed group who reported having a positive help-seeking intention increased by 35.1%, 32.1%, and 27.7%, respectively, and by 6.4%, 17.3%, and 15.2%, respectively in the non-distressed group. Multiple logistic regression analysis among participants having no help-seeking intention before exposure to the messages showed that message 2 had a significantly greater effect of increasing help-seeking intentions in the non-distressed group.@*CONCLUSION@#The exposure to persuasive messages may promote help-seeking intentions for depression. It seems likely that loss framing will work better than neutral and gain framing. Meanwhile, the responses to persuasive messages may differ to some extent between distressed and non-distressed individuals, as individuals with psychological distress are likely to be more susceptible to persuasive messages than those without.@*TRIAL REGISTRATION@#Not applicable; this is not a report of intervention trial.