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1.
Article in Japanese | WPRIM | ID: wpr-886198

ABSTRACT

Background: SOLO SMART (SOLO) was introduced in Japan as a new stentless tissue valve in April 2016. Postoperative thrombocytopenia has been reported to occurs after aortic valve replacement (AVR) using SOLO. Methods: The aim of our study was to evaluate the difference in incidence and clinical impact of postoperative thrombocytopenia in patients receiving AVR between SOLO group and stented bioprosthetic valve (Stented) group. We evaluated 67 patients who underwent AVR with bioprosthetic valve for AS between April 2017 and March 2020. Severe thrombocytopenia was defined as the lowest postoperative platelet count of < 5.0×104/μl. We divided patients with AVR into SOLO and Stented groups, and compared the surgical results, prevalence of thrombocytopenia, and changes in platelet count. Results: Postoperative aortic valve area (AVA) and peak pressure gradient (P-PG) were significantly improved in the SOLO group. The lowest postoperative platelet count was significantly lower in the SOLO group. Severe thrombocytopenia was observed in 75% of the patients in the SOLO group and 7% of those in the Stented group. As a factor that causes postoperative thrombocytopenia, use of SOLO, age at surgery, and body surface area (BSA), showed significant differences (p<0.05). Although the platelet count had the lowest value on the 2nd to 4th day after the operation, then recovered spontaneously, and at 1 month after the operation, the platelet level improved to normal values. However, in the Stented group, the platelet level recovered to the preoperative platelet level 1 week after operation, but in the SOLO group, the preoperative platelet level didn't recover even after 3 months, and as a result, it suggest that platelet recovery was prolonged in the SOLO group. Conclusion: Use of SOLO was an independent risk factor of severe thrombocytopenia after AVR. Although no clinically serious hemorrhagic complication was observed, use of SOLO may prolong postoperative platelet recovery. In consideration of the risk of thrombocytopenia, it was considered to be advantageous to select the SOLO for SAVR in cases with a narrow annulus diameter.

2.
Article in Japanese | WPRIM | ID: wpr-688466

ABSTRACT

SOLO SMART is a stentless bioprosthesis that comprises a larger effective orifice area and reduced pressure gradient, exhibiting a better hemodynamic profile than a stented bioprostheses. Currently, SOLO SMART finds application in patients with aortic valve diseases. However, patients with bicuspid aortic valve disease may present Valsalva sinus asymmetry. Recently, some studies have considered SOLO bioprosthesis as contraindicated in patients with a bicuspid aortic valve. Here, we report the case of a 79-year-old female with bicuspid aortic stenosis and Valsalva sinus asymmetry. We preoperatively assessed the aortic root of the patient using a novel 3D workstation that creates virtual reality (VR) images from cardiac CT data. After creating three symmetric commissures at the wall of the Valsalva sinus, we evaluated the distance from the coronary orifices. We determined the appropriate suture line of bioprosthesis avoid coronary orifice occlusion. Aortic valve replacement with SOLO SMART was successful, and the postoperative clinical course was uneventful. Hence, preoperative evaluation of the aortic root using VR images could be a precise and useful method for the assessment of the operative indication for SOLO SMART.

3.
Article in Japanese | WPRIM | ID: wpr-375905

ABSTRACT

A 63-year-old woman presented with pseudoaneurysm formation due to rupture of the porcine aortic wall of the stentless bioprosthesis. She had undergone aortic root replacement using the full root technique with the 25-mm Prima Plus bioprosthesis for annuloaortic ectasia. Congestive heart failure, appearing 65 months after the first surgery, progressed rapidly. Multidetector computed tomography (CT) showed a pseudoaneurysm of the aortic root, and echocardiography revealed severe mitral regurgitation. At reoperation, a large pseudoaneurysm with a 20-mm horizontal tear was seen in the non-coronary sinus of the Prima Plus valve. A repeat aortic root replacement and mitral valve replacement with two mechanical valves were performed. The patient had an uneventful recovery. Histologic examination of the explanted porcine aortic root showed host mononuclear cells and macrophages between the well-stained and poorly stained areas, suggesting that the torn tissue had undergone host-mediated degeneration to some extent. Porcine aortic roots have excellent hemodynamic features, but ruptures in the aortic sinuses of the porcine aortic root have been reported in some cases. Careful follow up with CT or echocardiography is therefore needed after aortic root replacement with stentless bioprostheses.

4.
Article in Japanese | WPRIM | ID: wpr-376894

ABSTRACT

A 72-year-old woman underwent a double aortic valve replacement with the Freestyle aortic bioprosthesis and subcoronary implantation with the Mosaic mitral bioprosthesis because of rheumatic multivalvular heart disease in 2000. During her annual follow-up, her Sinotubular junction was observed to have gradually increased in diameter on echocardiography and computed tomography. Therefore, 9 years after surgery we performed a reoperation for severe aortic regurgitation. Intraoperatively, the stentless bioprosthesis was found to be structurally intact. We believe that the dilation of the Sinotubular junction associated with a stentless bioprosthesis in the subcoronary position have caused her severe aortic regurgitation.

5.
Article in Japanese | WPRIM | ID: wpr-366793

ABSTRACT

A 34-year-old woman who was suffering from aortitis syndrome with annuloaortic ectasia (AAE) and severe aortic regurgitation (AR) from 18 years of age was admitted for an aortic root replacement. She has been on 5mg predonine daily. Aortography, CT and echocardiography examinations revealed dilated aortic annulus (D=30mm) and valsalva sinuses (D=43mm) and overstretched aortic valve leaflets. The ascending aorta was aneurysmal (D=50mm). Because of the patient's strong desire to have children, a Freestyle bioprosthesis was chosen for replacement. A collagen impregnated tube graft was interposed between the Freestyle and the proximal end of the transverse aorta. In order to reconstruct the coronary arteries, the Cabrol technique was utilized because of severe inflammatory adhesion of the aortic root. The patient had an uneventful postoperative course. This case shows that an aortic root replacement with Freestyle bioprosthesis offers a great benefit to those patients who are not suitable to receive postoperative anti-coagulation therapy to enable future pregnancy and child delivery.

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