ABSTRACT
Resumen: El Síndrome de Austrian, corresponde al cuadro clínico descrito por Robert Austrian en 1957, definido por la triada de Neumonía, Endocarditis Infecciosa (EI) y Meningitis, causado por Streptococcus pneumoniae. En la mayoría de los casos el vicio valvular presente, es la insuficiencia valvular aórtica, cuyo tratamiento médico y resolución quirúrgica de acuerdo con su gravedad, deben ser realizados precoz y oportunamente. Un paciente de 51 años, sin antecedentes de valvulopatía, con historia de poli consumo de alcohol y cocaína comenzó dos semanas previo a su ingreso hospitalario con síndrome febril, neumonía, y meningitis bacteriana por Streptococcus pneumoniae. Sus hemocultivos fueron negativos. El ecocardiograma transesofágico (ETE) fue compatible con EI valvular aórtica con insuficiencia moderada a severa. Se trató como EI a microorganismo desconocido y se efectuó un reemplazo valvular aórtico electivo con prótesis biológica a la 5° semana después de terminado el tratamiento médico antibiótico, cuyo resultado fue exitoso.
Abstract: A syndrome including Infective endocarditis, pneumonia and Meningitis caused by S pneumoniae was described by Robert Austrian in 1957. The aortic valve is affected in most cases. Medical followed by surgical treatment should be promptly implemented. The clinical case of a 51 year old man with a history of multiple drug consumption developing fever, pneumonia, and meningitis caused by S pneumoniae is presented. Blood cultures were negative and trans esophageal echocardiography showed aortic valve vegetations and moderate regurgitation. After multiple antibiotic treatment the patient underwent aortic valve replacement and recovered satisfactorily. Clinical and epidemiological characteristics of this syndrome are discussed.
Subject(s)
Humans , Male , Middle Aged , Pneumonia, Pneumococcal/surgery , Endocarditis, Bacterial/surgery , Meningitis, Pneumococcal/surgery , Pneumonia, Pneumococcal/diagnosis , Pneumonia, Pneumococcal/drug therapy , Streptococcus pneumoniae , Syndrome , Echocardiography, Transesophageal , Endocarditis, Bacterial/diagnosis , Endocarditis, Bacterial/drug therapy , Meningitis, Pneumococcal/diagnosis , Meningitis, Pneumococcal/drug therapy , Anti-Bacterial Agents/therapeutic useABSTRACT
Austrian syndrome is a triad characterized by pneumonia, meningitis and endocarditis, as a result of a Streptococcus pneumoniae bacteremia. We report a previously healthy 49 year-old male, who consulted at the emergency care unit with a history of one week of pleuritic pain, fever leading to an altered level of consciousness and seizures. A diagnosis of community-acquired pneumonia and meningitis was reached, isolating Streptococcus pneumoniae in the cerebrospinal fluid and blood cultures. Antibiotic treatment was started but the patient had an unsatisfactory response. During hospitalization a new heart murmur was found in the physical examination. An echocardiography was performed and a massive aortic valve insufficiency was found along with vegetations and a perforation of the same valve. The valve was replaced by a prosthetic one and the patient responded satisfactorily to the surgical and antibiotic treatment, without complications.
Subject(s)
Humans , Male , Middle Aged , Pneumonia, Pneumococcal/microbiology , Streptococcus pneumoniae/isolation & purification , Meningitis, Bacterial/microbiology , Endocarditis, Bacterial/microbiology , Pneumonia, Pneumococcal/surgery , Pneumonia, Pneumococcal/diagnostic imaging , Syndrome , Tomography, X-Ray Computed , Meningitis, Bacterial/surgery , Meningitis, Bacterial/diagnostic imaging , Endocarditis, Bacterial/surgery , Endocarditis, Bacterial/diagnostic imagingABSTRACT
Organizing Lobar Pneumonia is a rare form of Bronchiolitis Obliterans Organizing Pneumonia. Herein, we report a rare case of organizing pneumonia involving lung, mediastinum and esophagus. A 16-year-old girl was referred to our center with clinical signs and symptoms of dysphagia and weight loss. The main abnormal radiologic and endoscopic findings were stricture of the lower third of esophagus and calcified lobar pneumonia of the lung. Pathologic examination of biopsies taken from esophageal stricture and resected lung revealed fibrosis and organizing lobar pneumonia. This combination, to our knowledge, has not been reported previously