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1.
Mali méd. (En ligne) ; 36(2): 1-7, 20210812.
Article in French | AIM | ID: biblio-1283654

ABSTRACT

La COVID-19 est une infection virale qui s'est propagé dans tout le monde. Pour la prise en charge des cas, le Mali a créé des sites de traitement dont celui du CHU Gabriel Touré. Objectif : C'était d'analyser les prescriptions médicamenteuses pour le traitement de la COVID-19 au CHU Gabriel Touré. Méthodologie : L'étude était rétrospective et descriptive et a concerné la période d'avril à septembre 2020. Elle s'est déroulée au Centre de Traitement COVID-19 du CHU Gabriel Touré et à la Pharmacie Hospitalière de cet hôpital. Les ordonnances et les registres d'hospitalisation ont servi à collecter les données. Résultats : Au total, 29 patients ont été hospitalisés. L'âge médian était de 44ans, 75,90% des patients présentaient au moins une pathologie associée à la COVID-19. Le nombre d'ordonnances était de 333 comportant 870 lignes de prescriptions dont 33,21% de traitements standards et 66,79% pour les pathologies associées avec 86,23% disponibles à la Pharmacie Hospitalière. Le phosphate de chloroquine, dosé à 250mg, était administré à 500mg deux fois quotidiennement. Dans les directives nationales le phosphate de chloroquine était à 100mg pour 200mg trois fois quotidienne. La vitamine C non prévue dans les directives a été prescrite à tous les patients. La classe des médicaments du sang et des organes hématopoïétiques a été les plus prescrits (31,49%). Le coût moyen des traitements était de 65602±106858 FCFA avec maximum de 567860 FCFA. Une évaluation des prescriptions dans les autres sites de traitement est nécessaire.


COVID-19 was declared a pandemic in March 2020. For case management, Mali has created several treatment sites including the site of the CHU Gabriel Touré. Aims: The objective of the study was to analyse drug prescriptions for the COVID-19 treatment at the CHU Gabriel Touré. Methods: We performed a retrospective and descriptive study from April to September 2020. Drug prescriptions and hospital records were used to collect data. Prescriptions and hospital records were used to collect data. Results: A total of 29 patients were hospitalized. The median age was 44 years, 75.90% of patients had at least one pathology associated with COVID-19. The number of prescriptions was 333 comprising 870 lines of prescriptions including 33.21% for standard treatments, and 66.79% for associated pathologies. with 86.23% available at the Hospital Pharmacy. Chloroquine, dosed at 250mg, was administered at 500mg twice a day. The national guidelines from the treatment of COVID19 recommends 200mg of chloroquine in two doses. Vitamin C was prescribed for all patients although not included in the national guidelines. The class of drugs for the blood and blood-forming organs was the most prescribed (31.49%). The average cost of treatments was 65,602 ± 106,858 FCFA with a maximum of 567,860 FCFA. An evaluation of prescriptions in other treatment sites is necessary.


Subject(s)
Drug Prescriptions , COVID-19 , Guideline , Cost of Illness
2.
Int. j. med. surg. sci. (Print) ; 8(1): 1-12, mar. 2021. tab
Article in Spanish | LILACS | ID: biblio-1151620

ABSTRACT

El objetivo de este estudio fue caracterizar la prescripción de los medicamentos ansiolíticos utilizados en población de adultos mayores institucionalizados en el hogar de ancianos de Pinar del Río durante el año 2017.Se realizó un estudio descriptivo transversal, con recogida de datos retrospectiva, sobre prescripción de medicamentos ansiolíticos en la población de adultos mayores institucionalizados en el hogar de ancianos, se analizó la forma de utilización de los medicamentos, su indicación y prescripción con elementos de esquema terapéutico y factores que condicionan los hábitos de prescripción. Se trabajó con el universo (U= 98) de estudio el cual estuvo conformado por el total de pacientes institucionalizados, que estaban consumiendo ansiolíticos. Se revisaron las historias clínicas individuales y se confeccionó un modelo de recolección de datos.El medicamento más consumido por los adultos mayores fue el nitrazepam (41,8 %), siendo este a su vez el más consumido por el sexo masculino, no así para el femenino que resultó ser el clorodiazepóxido (64,6 %), el grupo de edad que más predominó fue el de 60-69 años, asimismo los viudos y el nivel educacional primario, el 79,5 % de los ancianos consume otros medicamentos que poseen interacción farmacocinética. El profesional que más indicó fue el médico de familia, la prescripción e intervalos entre dosis fue adecuada, la prescripción se consideró no racional.La prescripción de ansiolíticos en la población objeto de estudio, disminuye a medida que aumenta la edad, los más consumidores son los del sexo masculino y los institucionalizados por abandono familiar, esto apunta a la necesidad de continuar trabajando desde el nivel primario de atención dado que es de donde proceden estos ancianos.


The objective of this study was to characterize the prescription of anxiolytic medications used in the institutionalized elderly population at the Pinar del Río Nursing Home during 2017.A cross-sectional descriptive study was carried out, with retrospective data collection, on the prescription of anxiolytic medications in the population of institutionalized older adults in the Nursing Home, the form of use of the medications, their indication and prescription with elements of the therapeutic scheme was analyzed and factors that condition prescription habits. We worked with the universe (U = 98) of the study, which was made up of the total number of institutionalized patients who were consuming anxiolytics. Individual medical records were reviewed and a data collection model was created.The drug most consumed by older adults was nitrazepam (41.8%), this in turn being the most consumed by males, not so for females, which turned out to be chlorodiazepoxide (64.6%), the group The most prevalent age group was 60-69 years, likewise widowers and primary educational level, 79.5% of the elderly consume other drugs that have pharmacokinetic interaction. The professional who indicated the most was the family doctor, the prescription and intervals between doses were adequate, the prescription was considered non-rational.The prescription of anxiolytics in the population under study decreases as age increases, the most consumers are those of the male sex and those institutionalized due to family abandonment, this points to the need to continue working from the primary level of care since that is where these elders come from.


Subject(s)
Aged , Aged, 80 and over , Drug Prescriptions , Anti-Anxiety Agents/therapeutic use , Chlordiazepoxide/therapeutic use , Homes for the Aged , Nitrazepam/therapeutic use , Nursing Homes , Epidemiology, Descriptive , Cross-Sectional Studies , Retrospective Studies , Sex Distribution , Age Distribution
3.
Braz. oral res. (Online) ; 35: e011, 2021. tab, graf
Article in English | LILACS, BBO | ID: biblio-1142615

ABSTRACT

Abstract The objective of this study was to describe dental prescriptions of non-steroidal anti-inflammatory drugs (NSAID), opioids, and analgesics dispensed by the Brazilian National Health System (BNHS, SUS in Portuguese) of a Southeastern state from January to December 2017, and to analyze their association with socioeconomic and oral health care services' characteristics at municipal level. Data were collected from the Brazilian Integrated Pharmaceutical Care Management System. Medicines were grouped according to the Anatomical Therapeutic Chemical Classification System. The total number of Defined Daily Doses (DDD) and DDD per 1,000 inhabitants (inhab.) per year were presented and compared between groups of municipalities. Data analysis used the Classification and Regression Tree model performed with IBM SPSS 25.0. The total number of NSAID, opioids, and analgesics prescriptions was 70,747 and accounted for 354,221.13 DDD. The most frequently prescribed medicine was ibuprofen (n = 24,676; 34.88%). The number of dental practitioners in the BNHS per 1,000 inhab. (p < 0.001), first dental appointment coverage (p = 0.010), oral health teams per 1,000 inhab. (p=0.022), and the proportion of rural population (p = 0.014) were variables positively associated with the number of DDD of NSAID per 1,000 inhab. per year. Bolsa Família program coverage per 1,000 inhab. (p = 0.022) was negatively associated with NSAID prescription. Regarding analgesics, first dental appointment coverage (p=0.002) and Bolsa Família program coverage per 1,000 inhab. (p = 0.012) were positively associated with DDD per 1,000 inhab. per year. In conclusion, dental prescriptions of analgesics and NSAID in the BNHS were associated with socioeconomic and oral health care services' characteristics.


Subject(s)
Humans , Drug Prescriptions , Dentists , Brazil , Pharmaceutical Preparations , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Cities , Professional Role , Analgesics/therapeutic use , Analgesics, Opioid/therapeutic use
4.
Rev. panam. salud pública ; 45: e76, 2021. tab, graf
Article in English | LILACS | ID: biblio-1289870

ABSTRACT

ABSTRACT Objective. To describe bacterial resistance and antimicrobial consumption ratio at the subnational level in Argentina during 2018, considering beta-lactams group as a case-study. Methods. Antimicrobial consumption was expressed as defined daily doses (DDD)/1000 inhabitants. Resistance of Escherichia coli, Streptococcus pneumoniae, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus to beta-lactams was recorded. Resistance/consumption ratio was estimated calculating "R" for each region of Argentina, and this data was compared with other countries. Results. The most widely consumed beta-lactams in Argentina were amoxicillin (3.64) for the penicillin sub-group, cephalexin (0.786) for first generation cephalosporins, cefuroxime (0.022) for second generation; cefixime (0.043) for third generation and cefepime (0.0001) for the fourth generation group. Comparison between beta-lactams consumption and bacterial resistance demonstrated great disparities between the six regions of the country. Conclusions. The case-study of Argentina shows that antimicrobial consumption and resistance of the most common pathogens differed among regions, reflecting different realities within the same country. Because this situation might also be occurring in other countries, this data should be taken into account to target local efforts towards better antimicrobial use, to improve antimicrobial stewardship programs and to propose more suitable sales strategies in order to prevent and control antimicrobial resistance.


RESUMEN Objetivo. Determinar la razón entre la resistencia bacteriana y el consumo de antimicrobianos a nivel subnacional en Argentina en el 2018, considerando el grupo de los betalactámicos como estudio de caso. Métodos. El consumo de antimicrobianos se expresó como una dosis diaria determinada (DDD) por 1000 habitantes. Se registró la resistencia de Escherichia coli, Streptococcus pneumoniae, Pseudomonas aeruginosa, Klebsiella pneumoniae y Staphylococcus aureus a los betalactámicos. Se determinó la razón entre la resistencia y el consumo calculando "R" para cada región de Argentina, y estos datos se compararon con los de otros países. Resultados. Los betalactámicos más consumidos en Argentina fueron la amoxicilina (3,64) para el subgrupo de la penicilina; la cefalexina (0,786) para las cefalosporinas de primera generación; la cefuroxima (0.022) para las de segunda generación; la cefixima (0.043) para las de tercera generación, y la cefepima (0.0001) para el grupo de la cuarta generación. La comparación entre el consumo de betalactámicos y la resistencia bacteriana demostró que había grandes disparidades entre las seis regiones del país. Conclusiones. El estudio de caso en Argentina indica que el consumo de antimicrobianos y la resistencia a los patógenos más comunes difería entre las regiones; esto demuestra que hay distintas realidades dentro del mismo país. Como esta situación también se puede dar en otros países, estos datos se deben tener en cuenta para definir las actividades locales destinadas a fomentar un mejor uso de los antimicrobianos, para mejorar los programas de manejo de los antimicrobianos y para proponer estrategias de venta más adecuadas con el fin de prevenir y controlar la resistencia a los antimicrobianos.


RESUMO Objetivo. Descrever a relação entre o consumo de antimicrobianos e a resistência bacteriana no nível subnacional na Argentina em 2018, considerando o grupo dos betalactâmicos no estudo de caso. Métodos. O consumo de antimicrobianos foi representado por doses diárias definidas (DDD) por 1.000 habitantes. Foi registrada a resistência de Escherichia coli, Streptococcus pneumoniae, Pseudomonas aeruginosa, Klebsiella pneumoniae e Staphylococcus aureus aos betalactâmicos. A relação entre consumo e resistência foi calculada com base no "R" para cada região do país e os dados da Argentina foram comparados aos de outros países. Resultados. Os betalactâmicos de maior consumo na Argentina foram amoxicilina (3,64) no grupo das penicilinas, cefalexina (0,786) no grupo das cefalosporinas de primeira geração, cefuroxima (0.022) no grupo das cefalosporinas de segunda geração, cefixima (0.043) no grupo das cefalosporinas de terceira geração e cefepima (0.0001) no grupo das cefalosporinas de quarta geração. Ao se comparar o consumo de betalactâmicos e a resistência bacteriana, observou-se grande disparidade entre as seis regiões do país. Conclusões. O estudo de caso revela diferenças no consumo de antimicrobianos e na resistência dos patógenos mais comuns entre as regiões da Argentina, refletindo realidades distintas dentro do mesmo país. Como esta mesma situação pode estar ocorrendo em outros países, estes achados devem servir para direcionar os esforços locais a uma melhor utilização dos antimicrobianos, aperfeiçoar os programas de gestão do uso destes medicamentos e propor estratégias de venda mais apropriadas, visando a prevenir e controlar a resistência aos antimicrobianos.


Subject(s)
Humans , Drug Prescriptions/statistics & numerical data , beta-Lactam Resistance , Gram-Negative Bacteria/drug effects , Gram-Positive Bacteria/drug effects , Anti-Bacterial Agents/administration & dosage , Argentina , Retrospective Studies
5.
Rev. enferm. UERJ ; 28: e51482, jan.-dez. 2020.
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1146356

ABSTRACT

Objetivo: analisar o papel da enfermagem acerca da farmacoterapia da sífilis no âmbito da atenção primária em saúde. Método: investigação de abordagem qualitativa, com nove enfermeiros da atenção primária de município da Região Centro-Oeste do Brasil, realizada no período de agosto de 2018 a julho de 2019, por meio de entrevistas. A análise de dados apoiou-se na Teoria de Enfermagem Sócio-Humanista. Resultado: o papel da enfermagem esteve circunscrito à consulta de enfermagem, mediantes ações de acolhimento, escuta, detecção da sífilis, prescrição e administração de medicamento e práticas educativas. O aporte institucional caracterizou-se pela elaboração de protocolo sobre prescrição de medicamentos pelo enfermeiro e construção de fluxo de atenção ao usuário com sífilis. Conclusão: a enfermagem atua com autonomia na farmacoterapia da sífilis pautada em suas experiências e conhecimentos, aporte institucional, trabalho em equipe, procurando atender às necessidades de saúde do usuário.


Objective: to examine nursing's role in syphilis drug therapy in the primary health care context. Method: this qualitative study of nine primary care nurses in a municipality in Brazil's Midwest Region was conducted, by interview, from August 2018 to July 2019. Data analysis was based on the Social-Humanist Nursing Theory. Result: nursing's role was limited to nursing appointments, and took the form of welcoming reception, listening, syphilis detection, medication prescription and administration, and educational activities. The institutional contribution was characterized by preparation of a protocol on medication prescription by nurses and construction of the care flow for users with syphilis. Conclusion: nursing operates autonomously in syphilis drug therapy, seeking to meet user health needs based on its experience and knowledge, institutional support, and teamwork.


Objetivo: examinar el papel de la enfermería en la terapia con medicamentos para la sífilis en el contexto de la atención primaria de salud. Método: este estudio cualitativo de nueve enfermeras de atención primaria en un municipio de la Región Medio Oeste de Brasil se realizó, por entrevista, de agosto de 2018 a julio de 2019. El análisis de datos se basó en la Teoría de Enfermería Social-Humanista. Resultado: la función de la enfermería se limitó a las citas de enfermería y se concretó en la recepción de bienvenida, la escucha, la detección de la sífilis, la prescripción y administración de medicamentos y actividades educativas. El aporte institucional se caracterizó por la elaboración de un protocolo de prescripción de medicamentos por enfermeras y la construcción del flujo de atención a usuarios con sífilis. Conclusión: la enfermería opera de manera autónoma en la terapia con medicamentos para la sífilis, buscando satisfacer las necesidades de salud de los usuarios a partir de su experiencia y conocimiento, apoyo institucional y trabajo en equipo.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Drug Prescriptions/nursing , Primary Health Care , Syphilis/nursing , Nurse's Role , Nursing Theory , Brazil , Syphilis/drug therapy , Qualitative Research , User Embracement , Nurse-Patient Relations
6.
Bol. méd. postgrado ; 36(2): 21-25, dic.2020. tab, graf
Article in Spanish | LILACS, LIVECS | ID: biblio-1117893

ABSTRACT

El síndrome de lisis tumoral (SLT) es una complicación potencialmente letal provocada por la liberación masiva de ácidos nucleicos, potasio y fosfato hacia la circulación sistémica lo cual se asocia a graves trastornos del metabolismo hidroelectrolítico. Se realizó una revisión retrospectiva de historias clínicas con el objetivo de describir las características clínicas de los pacientes con sospecha de SLT que ingresaron al Servicio de Medicina Interna del Hospital General Universitario Dr. Luis Gómez López durante el lapso 2017-2018. El 50% de los pacientes tenían una edad comprendida entre 51 y 70 años, siendo el 65% de sexo femenino. Los canceres más frecuentemente encontrados fueron el cáncer de mama (29%), cáncer gástrico (15%) y el linfoma no Hodgkin (12%). Todos los pacientes presentaron al menos tres de las manifestaciones clínicas asociadas al SLT entre las cuales se encuentran náuseas, vómitos, anorexia, debilidad, calambres, hiperreflexia, oliguria, anuria, hematuria, hipotensión, convulsiones y deshidratación. El 46% de los pacientes presentaron hiperpotasemia, mientras que 36% mostraron hipocalcemia y 18% hiperfosfatemia. El 76% de los pacientes cursaron con una creatinina > 1,4 mg/dl. El diagnóstico definitivo de SLT no fue posible realizarlo en ninguno de los pacientes incluidos en este estudio debido a la falta de estudios paraclínicos necesarios para satisfacer los criterios según los lineamientos internacionales(AU)


Tumor lysis syndrome (TLS) is a potentially lethal complication due to massive release of nucleic acids, potassium and phosphate into the systemic circulation which is associated with severe hydroelectrolitic metabolic disorders. A retrospective review of clinical charts was performed in order to describe clinical characteristics of patients with possible TLS that were admitted to the Servicio de Medicina Interna of the Hospital General Universitario Dr. Luis Gómez López during the period 2017-2018. The results show that 50% of patients were between 51 and 70 years old and 65% were female. Breast cancer (29%), stomach cancer (15%) and Non-Hodgkin lymphoma (12%) were more frequent in patients with possible TLS. All patients showed at least three of the clinical features commonly associated with TLS such as nausea, vomiting, anorexia, weakness, cramps, hyperreflexia, oliguria, anuria, hematuria, hypotension, convulsion and dehydration. 46% of patients had hyperkalemia, 36% hypocalcemia and 18% hyperphosphatemia. Creatinine levels > 1,4 mg/dl were seen in 76% of patients. Definitive diagnosis of TLS was not possible in any of the patients included in this study due to the lack of laboratory studies required according to international guidelines(AU)


Subject(s)
Humans , Phosphates , Potassium , Radiotherapy , Breast Neoplasms , Nucleic Acids , Tumor Lysis Syndrome/physiopathology , Drug Therapy , Drug Prescriptions , Critical Care , Hematology , Internal Medicine , Medical Oncology
7.
Nursing (Säo Paulo) ; 23(268): 4589-4607, set.2020.
Article in Portuguese | LILACS, BDENF | ID: biblio-1145305

ABSTRACT

Objetivos: Descrever a percepção do graduando de enfermagem sobre a segurança do paciente no Sistema de distribuição de Medicamentos por Dose unitária - SDMDU. Método: Pesquisa de campo exploratória, quantitativa, qualitativa, não probabilística intencional. Realizada em um hospital infantil que utiliza o SDMDU. Foram entrevistados 126 graduandos de enfermagem. Resultados: Percepção positiva para 99(78,57%) dos graduandos de enfermagem, categorizado por Sistema Seguro 45 (45,45%) e, 30(30,30%) relatam que o SDMDU diminui erros. Entretanto 21(16,67%) referiram percepção negativa, afirmam que o Preparo e Administração dos medicamentos 10(47,61%) devem ocorrer pela enfermagem e, consideram o Sistema inseguro, 9(42,85%) entrevistados. Considerações Finais: O SDMDU é um processo que traz maior segurança ao paciente. O enfermeiro deve conhecer a responsabilidade sobre a administração de medicamentos como algo importante dentro do conjunto de atividades que realiza, uma vez que a implantação do SDMDU reflete diretamente nas atividades da equipe de enfermagem.(AU)


Objectives: To describe the perception of nursing students on patient safety in the Distribution System of Medicines by Unit Dose - SDMDU. Method: Exploratory, quantitative, qualitative, non-probabilistic, intentional field research. Held in a children's hospital that uses the SDMDU. 126 nursing graduates were interviewed. Results: Positive perception for 99 (78.57%) of nursing students, categorized by Sistema Seguro 45 (45.45%) and 30 (30.30%) report that the SDMDU decreases errors. However, 21 (16.67%) reported a negative perception, affirm that the Preparation and Administration of medicines 10 (47.61%) must be performed by nursing staff and, considering the System unsafe, 9 (42.85%) interviewed. Final Considerations: The SDMDU is a process that brings greater safety to the patient. The nurse must know the responsibility for medication administration as something important within the set of activities that he performs, since the implementation of the SDMDU reflects directly on the activities of the nursing team.(AU)


Objetivos: Describir la percepción de los estudiantes de enfermería sobre la seguridad del paciente en el Sistema de Distribución de Medicamentos por Unidad Dosis - SDMDU. Método: Investigación de campo exploratoria, cuantitativa, cualitativa, no probabilística e intencional. Se lleva a cabo en un hospital de niños que utiliza la SDMDU. Se entrevistaron 126 graduados en enfermería. Resultados: La percepción positiva para 99 (78.57%) de estudiantes de enfermería, categorizados por Sistema Seguro 45 (45.45%) y 30 (30.30%) informan que el SDMDU disminuye los errores. Sin embargo, 21 (16,67%) informaron una percepción negativa, afirman que la preparación y administración de medicamentos 10 (47,61%) debe ser realizada por personal de enfermería y, considerando que el sistema no es seguro, 9 (42,85%) entrevistados. Consideraciones Finales: SDMDU es un proceso que brinda mayor seguridad al paciente. La enfermera debe conocer la responsabilidad de la administración de medicamentos como algo importante dentro del conjunto de actividades que realiza, ya que la implementación de la SDMDU se refleja directamente en las actividades del equipo de enfermería.(AU)


Subject(s)
Humans , Drug Prescriptions/nursing , Students, Nursing , Patient Safety , Medication Errors/prevention & control , Fractionated Drugs , Medication Systems, Hospital
8.
Revista Digital de Postgrado ; 9(2): 211, ago. 2020.
Article in Spanish | LILACS, LIVECS | ID: biblio-1103439

ABSTRACT

En años recientes los venezolanos hemos enfrentado problemas de diversa índole con relación a la situación de salud. Entre ellos, problemas en la prescripción y la obtención de medicamentos. En esta publicación se tratarán aspectos importantes para la correcta prescripción y obtención de medicamentos, lo cual, a su vez, debería ser el colofón de la atención médica de primera que siempre ha caracterizado a nuestro país y que hoy, lamentablemente, ha devenido en una situación muy dolorosa. La prescripción y obtención de medicamentos puede verse dificultada por diversos inconvenientes, entre los cuales podemos considerar aquellos que tienen relación con el medicamento propiamente dicho, con el prescriptor y el cliente, con las regulaciones vigentes en nuestro país y con la disponibilidad en los centros autorizados para su venta. Como consecuencia de una prescripción inadecuada y un consumo inapropiado de medicamentos pueden surgir problemas muy serios, entre los cuales habría que destacar, en el campo de los antiinfecciosos, la resistencia bacteriana. Y en el campo de fármacos destinados al tratamiento del dolor, la ansiedad y el insomnio, la posibilidad de adicciones diversas. La prescripción adecuada de medicamentos conlleva la necesidad de conocer, a la par de los efectos beneficiosos y terapéuticos de los mismos, la posibilidad de efectos adversos e interacciones. Todos los prescriptores sanitarios deben conocer los fundamentos de la Farmacovigilancia, la cual permitirá conocer el verdadero balance riesgo-beneficio de los fármacos, por lo cual hacemos una breve mención de la misma al final de esta presentación(AU)


In recent years, Venezuelans have faced various kinds of problems related to the health situation. Among them, problems in prescription and acquisition of medicines. This publication will discuss important aspects for the correct prescription and obtention of medicines, which, in turn, should be the culmination of the excellent medical care that has always characterized our country but that today, unfortunately, has become a very disgraced and sad situation. Prescription and acquisition of medicines can be hindered by various inconveniences, among which we can consider those that are related to the product itself, to the prescriber and the client, to the regulations in force in our country and to the availability in authorized centers for sale. As a result of an inadequate prescription and consumption of medications, very serious problems can arise, among which, in the field of anti-infectives, bacterial resistance should be highlighted. In the field of drugs for the treatment of pain, anxiety and insomnia, the possibility of diverse addictions. Proper prescription of medicaments entails the need to know, along with their beneficial and therapeutic effects, the possibility of adverse effects and interactions. All health prescribers must know the basics of Pharmacovigilance, which allow to know the true risk-benefit balance of drugs, so we make a brief mention of it at the end of this presentation.(AU)


Subject(s)
Humans , Drug Prescriptions/standards , Drug Resistance, Microbial , Right to Health , Pharmacology, Clinical , Sanitary Specifications , Pharmacovigilance
9.
J. nurs. health ; 10(3): 20103007, jul.2020.
Article in Portuguese | LILACS, BDENF | ID: biblio-1129508

ABSTRACT

Objetivo: analisar perfil dos erros de prescrição e aprazamento de antimicrobianos em uma unidade de clínica médica. Método: pesquisa observacional com 45 prontuários e 72 prescrições de uma unidade de clínica em um hospital no Piauí. A coleta foi entre setembro e outubro de 2017, por preenchimento de checklist e a análise dos dados foi descritiva. Resultados: as cefalosporinas foram a subclasse farmacológica mais prescrita, 52,8%. Os erros de prescrição mais frequentes foram de ausência de 76,4% de informações quanto ao tempo de duração do tratamento e de 93,1% da descrição da forma farmacêutica. Os erros do aprazamento registrados foram 18,6% de ordem de administração em prescrições com mais de um antimicrobiano e 11,1% de mudança de horários sem indicação terapêutica, ao longo do tratamento. Conclusão: o perfil dos erros de prescrição mais frequentes foi de inconformidades de aprazamento, sendo necessárias medidas de controle e vigilância por parte da instituição.(AU)


Objective: to analyze the profile of prescription and scheduling antimicrobials errors in a medical clinic unit. Method: observational research with 45 medical records and 72 prescriptions from a clinical unit in a hospital in Piauí. The collection took place between September and October 2017, by completing the checklist and the data analysis was descriptive. Results: cephalosporins were the most prescribed pharmacological subclass, 52.8%. The most frequent prescription errors were the absence of 76.4% of information regarding the duration of treatment and 93.1% of the description of the pharmaceutical form. The scheduling errors recorded were 18.6% of order of administration in prescriptions with more than one antimicrobial and 11.1% of scheduling changes without therapeutic indication, throughout the treatment. Conclusion: the profile of the most frequent prescription errors was that of nonconformities with the scheduling, requiring control and surveillance measures by the institution.(AU)


Objetivo: analizar el perfil de errores de prescripción y programación de antimicrobianos en una unidad de clínica médica. Método: investigación observacional con 45 historias clínicas y 72 recetas de una unidad en un hospital de Piauí. La recolección se realizó entre septiembre y octubre de 2017, completando el checklist y el análisis fue descriptivo. Resultados: las cefalosporinas fueron la subclase farmacológica más prescrita, 52,8%. Los errores de prescripción más frecuentes fueron la ausencia del 76,4% de información sobre la duración del tratamiento y del 93,1% de la descripción de la forma farmacéutica. Los errores de programación registrados fueron el 18,6% de orden de administración con más de un antimicrobiano y el 11,1% de cambios programación sin indicación terapéutica, a lo largo del tratamiento. Conclusión: el perfil de los errores de prescripción más frecuentes fue el de incumplimiento de programación, requiriendo medidas de control y vigilancia por parte de la institución.(AU)


Subject(s)
Drug Prescriptions , Medication Errors , Anti-Bacterial Agents
10.
Semina cienc. biol. saude ; 41(2, Supl.): 367-376, jun./dez. 2020. Tab
Article in Portuguese | LILACS | ID: biblio-1247560

ABSTRACT

Apesar do uso de medicamentos durante a gestação ser um assunto bastante polêmico, existe consenso que o uso desnecessário pode provocar efeitos irreparáveis ao feto. Com o objetivo de descrever o uso de medicamentos prescritos, realizou-se um estudo descritivo em gestantes em pré-natal de três unidades do Sistema Único de Saúde (SUS) no município de Dourados, estado de Mato Grosso do Sul. Os dados sobre o uso de medicamentos foram coletados através de consulta à cópia das prescrições e prontuários das gestantes. Foram analisadas 115 receitas medicamentosas para gestantes atendidas em consultas de rotinas, sendo encontrada a média de 1,4 medicamento por prescrição; sendo 77,8% prescritos pelo nome genérico, 89 % constavam na Relação Municipal de Medicamentos Essenciais, enquanto 81% constavam na Relação Nacional de Medicamentos Essenciais. As preparações antianêmicas foram prescritas em todos os trimestres de gestação, já os analgésicos apareceram numa frequência maior no segundo e terceiro trimestres, bem como os antibacterianos de uso sistêmico. O sulfato ferroso, ácido fólico e paracetamol foram os medicamentos mais prescritos, sendo a maioria pertencente às classes A e B segundo o potencial de risco pela Food and Drug Administration (FDA). A prescrição de medicamentos a gestantes atende aos indicadores de prescrição da Organização Mundial da Saúde (OMS). O uso de medicamentos é frequente e a maioria das gestantes utilizou um ou mais fármacos prescritos durante a gestação.(AU)


Although the use of medications during pregnancy is a very controversial subject, there is a consensus that unnecessary use can cause irreparable effects on the fetus. In order to describe the use of prescription drugs, a descriptive study was carried out on pregnant women in prenatal care at three units of the Unified Health System (SUS) in the city of Dourados, State of Mato Grosso do Sul. use of medicines was collected through consultation with a copy of the prescriptions and medical records of the pregnant women. 115 medication prescriptions for pregnant women attended in routine consultations were analyzed, with an average of 1.4 medications per prescription; 77.8% of which were prescribed by the generic name, 89% were on the Municipal List of Essential Medicines, while 81% were on the National List of Essential Medicines. Anti-anemic preparations were prescribed in all trimesters of pregnancy, while painkillers appeared more frequently in the second and third trimesters, as well as antibacterials for systemic use. Ferrous sulfate, folic acid and paracetamol were the most prescribed drugs, with the majority belonging to classes A and B according to the risk potential by the Food and Drug Administration (FDA). The prescription of medications to pregnant women meets the prescription indicators of the World Health Organization (WHO). The use of medications is frequent, and most pregnant women used one or more drugs prescribed during pregnancy.(AU)


Subject(s)
Humans , Drug Prescriptions , Unified Health System , Health , Pregnant Women , Prescription Drugs , World Health Organization , Drugs, Essential , Drug Utilization
11.
Rev. méd. Chile ; 148(6): 842-848, jun. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1139379

ABSTRACT

The prescription of medications is a weak link in the therapeutic chain of a drug. Medication errors can be associated with the use of so-called unsafe abbreviations in medical prescription. When they are mistakenly interpreted by the person who reads the prescription, error becomes imminent. We herein review the literature about the use of unsafe abbreviations in medical prescriptions and their association with medication errors. PubMed and Lilacs were reviewed, and 29 studies were analyzed, extracting information about the use of abbreviations, common abbreviations, reasons for their use and tools to reduce this conduct. A list with the main risky health abbreviations adapted to Chile was generated. It became clear that the use of abbreviations has increased, appearing in almost all medical prescriptions. The most commonly used abbreviations are the acronym "u" referring to units, followed by "sc" referring to subcutaneous. One of the causes for the use of acronyms the limited time that doctors have at the time of prescription. One way to reduce the use of these abbreviations, is to remind constantly about those that may have the greatest risk in each health institution. A list of unsafe abbreviations, to be used by Chilean health services, is proposed.


Subject(s)
Humans , Drug Prescriptions , Medication Errors/prevention & control , Chile
13.
Mem. Inst. Invest. Cienc. Salud (Impr.) ; 18(1)abr. 2020. ilus, tab
Article in Spanish | LILACS, BDNPAR | ID: biblio-1291623

ABSTRACT

El uso descontrolado de los antibióticos favoreció el desarrollo de resistencia bacteriana que va aumentando considerablemente conforme van pasando los años y se ha convertido en una de las mayores amenazas para la salud pública. Es por ello que el Ministerio de Salud Pública y Bienestar Social (MSPyBS) emitió la Resolución S.G. N° 576/18 en la que se dispone la venta obligatoria de medicamentos que tengan actividad antibiótica de uso sistémico bajo receta simple archivada. El objetivo de este trabajo fue medir el nivel de conocimiento y práctica de la normativa de la receta simple archivada para la prescripción de antibióticos de uso sistémico en odontólogos de Asunción y Gran Asunción. El diseño del estudio fue observacional descriptivo, de corte transversal, en donde participaron 190 profesionales odontólogos. Los resultados obtenidos en este estudio mostraron que el 77,89% de los odontólogos respondió que conoce la Resolución S.G. N° 576/18 del MSPyBS, y 94,21% respondió que sabe qué datos incluir en la receta simple archivada. Sólo 11,28% incluye correctamente todos los datos requeridos. También se pudo observar que la amoxicilina es el antibiótico más recetado por los odontólogos (79,47%). En conclusión, se observó que solo el 40,0% de los profesionales encuestados tuvieron un nivel de conocimiento suficiente, mientras que el 60,52% tuvo un nivel de práctica adecuado


The uncontrolled use of antibiotics favored the development of bacterial resistance that has increased considerably in the last years and has become one of the greatest threats to public health. This is the reason why the Ministry of Public Health and Social Welfare (MSPyBS) issued the Resolution SG No. 576/18, which stipulates the mandatory sale of drugs that have systemic antibiotic activity under a simple archived prescription. The aim of this study was to measure the level of knowledge and practice on the regulation of the simple archived prescription for systemic antibiotics of dentists in Asunción and Gran Asunción. The study design was descriptive, cross-sectional and 190 dentists participated. The results showed that 77.89% of dentists knew about Resolution S.G. No. 576/18 of the MSPyBS, and 94.21% replied that they knew what information to include in the simple archived prescription. Only 11.28% correctly included all the required data. It was also observed that amoxicillin was the most prescribed antibiotic by dentists (79.47%). In conclusion, it was observed that only 40.0% of the professionals surveyed had a sufficient level of knowledge, while 60.52% had an adequate level of practice


Subject(s)
Humans , Male , Female , Drug Resistance, Microbial , Anti-Bacterial Agents , Drug Prescriptions , Public Health
14.
REME rev. min. enferm ; 24: e1311, fev.2020. tab
Article in Portuguese | LILACS, BDENF | ID: biblio-1125469

ABSTRACT

RESUMO Objetivo: analisar as prescrições de medicamentos potencialmente perigosos e identificar as práticas adotadas na dispensação em hospital universitário público de alta complexidade, propondo estratégias para prevenção de eventos adversos. Métodos: estudo transversal realizado com 566 prescrições, em três turnos, no período de abril a dezembro de 2016. A identificação de práticas para dispensação foi por observação direta com aplicação de checklist baseado no protocolo do Ministério da Saúde (MS) /Agência Nacional de Vigilância Sanitária (ANVISA). Utilizou-se teste não paramétrico do qui-quadrado de independência para avaliar a associação entre prescrições com e sem medicamentos potencialmente perigosos e unidades de internação. Resultados: mais da metade das prescrições (56,6%) continha dois ou mais medicamentos potencialmente perigosos e quase todos injetáveis (95,4%), principalmente analgésicos opioides (31,2%), glicose 50% (24,7%) e insulina NPH e regular (24,3%). A taxa dos prescritos correspondeu a 18,2%. As principais práticas que representaram riscos foram: distribuição coletiva de cloreto de potássio e insulina; falta de etiquetas de alerta; dupla conferência inexistente; uso de fontes de interrupção/distração em 43,9% das prescrições atendidas. Conclusão: apesar de serem frequentes em mais da metade das prescrições, as práticas adotadas na dispensação de medicamentos potencialmente perigosos foram insuficientes para uma dispensação segura, podendo comprometer a administração desses medicamentos e causar danos aos pacientes. É importante a implementação do protocolo do MS/ANVISA para prevenção de erros de medicação, em consonância com o terceiro desafio global da Organização Mundial da Saúde (OMS).


RESUMEN Objetivo: analizar las prescripciones de medicamentos potencialmente peligrosos e identificar las prácticas adoptadas en la dispensación en un hospital universitario público de alta complejidad, proponiendo estrategias para prevenir eventos adversos. Métodos: estudio transversal realizado con 566 prescripciones, en tres turnos, de abril a diciembre de 2016. La identificación de prácticas de dispensación se realizó mediante observación directa con aplicación de una lista de verificación basada en el protocolo del Ministerio de Salud (MS) / Agencia Nacional de Vigilancia Sanitaria (ANVISA). Se utilizó una prueba de independencia chi-cuadrado no paramétrica para evaluar la asociación entre las prescripciones con y sin medicamentos potencialmente peligrosos con unidades de hospitalización. Resultados: más de la mitad de las prescripciones (56.6%) contenían dos o más fármacos potencialmente peligrosos , la mayoría inyectables (95.4%), principalmente analgésicos opioides (31.2%), glucosa 50% (24.7%) e insulina NPH y regular (24.3%). La tasa de prescripción correspondió al 18,2%. Las principales prácticas que representaban riesgos fueron: distribución colectiva de cloruro de potasio e insulina; falta de etiquetas de advertencia; falta de doble verificación; uso de fuentes de interrupción / distracción en el 43,9% de las prescripciones atendidas. Conclusión: a pesar de ser frecuente en más de la mitad de las prescripciones, las prácticas adoptadas en la dispensación de fármacos potencialmente peligrosos fueron insuficientes para la dispensación segura, lo que podría comprometer la administración de estos medicamentos y perjudicar a los pacientes. Es importante implementar el protocolo MS/ANVISA para prevenir errores de medicación, en línea con el tercer desafío global de la Organización Mundial de la Salud (OMS).


ABSTRACT Objective: to analyze the prescriptions of high alert medications and to identify the practices adopted in the dispensing in a high complexity public university hospital, proposing strategies to prevent adverse events. Methods: a cross-sectional study carried out with 566 prescriptions, in three shifts, from April to December 2016. The identification of practices for dispensing was by direct observation with the application of a checklist based on the protocol of the Ministry of Health (MH)/National Health Surveillance Agency(ANVISA) (Ministério da Saúde/Agência Nacional de Vigilância Sanitária). A non-parametric chi-square test of independence was used to assess the association between prescriptions with and without high alert medications and inpatient units. Results: more than half of the prescriptions (56.6%) contained two or more high alert medications and almost all were injectable (95.4%), mainly opioid analgesics (31.2%), glucose 50% (24.7%), and NPH and regular insulin (24.3%). The prescription rate corresponded to 18.2%. The main practices that represented risks were the following: collective distribution of potassium chloride and insulin; lack of warning labels; non-existent double check; presence of interruption/distraction sources in 43.9% of the prescriptions met. Conclusion: despite being frequent in more than half of the prescriptions, the practices adopted in the dispensing of high alert medications were insufficient for a safe dispensing, which could compromise the administration of these drugs and cause harm to the patients. It is important to implement the MH/ANVISA protocol for preventing medication errors, in consonance with the third global challenge of the World Health Organization (WHO).


Subject(s)
Humans , Drug Prescriptions , Protocols , Hospitals , Hospitals, University , Medication Errors , Nursing Service, Hospital , World Health Organization , Brazilian Health Surveillance Agency , Potentially Inappropriate Medication List/organization & administration
15.
rev. cuid. (Bucaramanga. 2010) ; 11(1): e798, Ene.-2020.
Article in Spanish | LILACS, BDENF, COLNAL | ID: biblio-1118234

ABSTRACT

Introducción: Frente a una moción parlamentaria que pretende modificar el código sanitario para permitir a los enfermeros tener la facultad legal de prescribir fármacos y dispositivos sanitarios surge la inquietud de analizar la representación social que los enfermeros de atención primaria de salud otorgan a la temática. Objetivo: Describir los componentes figurativos (campo de representación), simbólico (información) y afectivo (actitudinal) del cuidar mediante la prescripción enfermera, que tienen los profesionales de enfermería de la red de atención primaria de salud. Materiales y Métodos: Investigación descriptiva con enfoque cualitativo y diseño de teoría fundamentada, realizada en ocho enfermeras de la red de atención primaria de salud a través de entrevista semiestructurada. Resultados: En la representación social de la prescripción enfermera surgen cinco categorías: gestionar el cuidado, beneficios sociales de la prescripción, restricción en la prescripción, formación profesional del enfermero en prescripción y valor atribuido a la prescripción. Discusión: Las enfermeras de atención primaria, entienden el fenómeno de la prescripción como una indicación de enfermería que se encuentra influenciada por factores asociados a la formación farmacológica de pregrado y la experiencia laboral, similar a lo reportado en algunos estudios en Iberoamérica. Conclusiones: Las enfermeras consideran que la prescripción es un elemento positivo para la entrega de cuidados y que contribuye a la resolutividad en la atención de salud, sin embargo, para llevarla a cabo se requiere de una formación adecuada y de un respaldo legal claro.


Introduction: Considering that a parliamentary motion seeks to modify the health code to allow nurses to have the legal power to prescribe drugs and health devices, it is necessary to analyze the social representation that primary healthcare nurses give to prescription. Objective: To describe the figurative (representation field), symbolic (information) and affective (attitudinal) nursing components by means of nurse prescription used by primary health care nursing professionals. Materials and Methods: A descriptive qualitative research with a grounded theory research design was conducted with eight nurses from the primary healthcare network through a semi-structured interview. Results: Five categories were created based on the social representation of nurse prescription: care management, social benefits of prescription, prescription restriction, professional nurse training in prescription, and value attributed to the prescription. Discussion: Primary care nurses perceive the prescription phenomenon as a nursing indication that is influenced by factors associated with undergraduate pharmacology training and work experience, similar to that reported in some studies in Ibero-America. Conclusions: Nurses consider that nurse prescription is a positive element for care delivery, contributing to the resolutive capacity of healthcare. However, adequate training and clear legal support are required to do so.


Introdução: Frente a uma moção parlamentar que objetiva emendar o código sanitário para permitir que os enfermeiros tenham a faculdade legal de prescrever fármacos e dispositivos sanitários surge a inquietude de analisar a opinião dos enfermeiros de atendimento primário em saúde sobre a sua representação social a respeito dessa questão. Objetivo: Descrever os componentes figurativo (campo de representação), simbólico (informação) e afetivo (atitudinal) do cuidar mediante a prescrição de enfermagem que os profissionais da rede de enfermagem detêm na rede de atendimento primário em saúde. Materiais e Métodos: Pesquisa descritiva com abordagem qualitativa e desenho de teoria fundamentada, realizada com oito enfermeiras da rede de atendimento primário em saúde através de uma entrevista semiestruturada. Resultados: Na representação social da prescrição de enfermagem surgem cinco categorias: administrar o cuidado, os benefícios sociais da prescrição, restrições na prescrição, formação profissional em prescrição do enfermeiro e valor atribuído à prescrição. Discussão: As enfermeiras de atendimento primário compreendem o fenómeno da prescrição como uma indicação de enfermagem influencia por fatores associados à formação farmacológica de pré-graduação e a experiência de trabalho, semelhante àquela relatada em vários estudos na Ibero-América. Conclusões: As enfermeiras consideram que a prescrição é um elemento positivo para a entrega de cuidados e que contribui com a resolutividade no atendimento em saúde, no entanto, para cumprir essa tarefa é preciso contar com uma formação adequada e um fundamento legal claro.


Subject(s)
Humans , Male , Female , Drug Prescriptions , Primary Health Care , Chile , Nurses, Male
16.
Article in English | WPRIM | ID: wpr-811269

ABSTRACT

OBJECTIVES: This study aimed to understand the nationwide patterns of antibiotic prescription after tooth extraction in adult patients.MATERIALS AND METHODS: This study analyzed dental records from the National Health Insurance Service–National Sample Cohort (NHIS–NSC) database on 503,725 tooth extractions performed in adults (≥19 years) during 2011–2015. Patient sex, age, household income, systemic disease (diabetes mellitus and hypertension), type of dental institution, region of dental institution, year of prescription, and type of tooth extraction procedure were considered. The antibiotic prescription rate and broad-spectrum antibiotic prescription frequency were analyzed using chi-squared tests. Factors affecting the prescription of broad-spectrum antibiotics were evaluated using multivariate logistic regression analysis.RESULTS: The rate of antibiotic prescription after tooth extraction was 81.85%. Penicillin was most commonly prescribed (45.25%), followed by penicillin with beta-lactamase inhibitors (18.76%), metronidazole (12.29%), and second- to fourth-generation cephalosporins (11.52%). The proportion of broad-spectrum antibiotics used among all prescribed antibiotics was 45.88%.CONCLUSION: The findings of this study demonstrate that the rate of antibiotic prescription after tooth extraction is higher in Korea than in other countries. Furthermore, broad-spectrum antibiotics are used more frequently, which may indicate unnecessary drug prescription, an important contributor to antibiotic resistance.


Subject(s)
Adult , Anti-Bacterial Agents , beta-Lactamase Inhibitors , Cephalosporins , Cohort Studies , Dental Records , Drug Prescriptions , Drug Resistance, Microbial , Family Characteristics , Humans , Korea , Logistic Models , Metronidazole , National Health Programs , Penicillins , Prescriptions , Tooth Extraction , Tooth
17.
Rev Assoc Med Bras (1992) ; 66(7): 913-917, 2020. graf
Article in English | LILACS, SES-SP | ID: biblio-1136322

ABSTRACT

SUMMARY OBJECTIVES To evaluate the frequency of prescription of proton pump inhibitors (PPIs) and their indications in patients hospitalized at the Hospital de Clínicas of the Federal University of Uberlândia (HC-UFU). METHODS This is a quantitative cross-sectional observational study that analyzes data obtained from patient records on prescriptions of PPIs for patients hospitalized at the HC-UFU and from a questionnaire applied to assistant physicians on the indications of the drug in each case and evaluates the indication based on literature data. RESULTS On a pre-determined day, of a total of 462 inpatients, there was a prescription of PPI for 183 (39.3%), with a higher frequency (73.5%) in the Intensive Care Unit (ICU), followed by the infirmaries and the Emergency Room. The assistant physician was located in 116 cases, and the main motivation referred to prescription was prophylaxis of digestive hemorrhage (77%). However, after reviewing medical records, it was noticed that in 50.8% of the cases, the prescription was not supported by the literature. CONCLUSION The frequency of PPI prescriptions for inpatients in the HC-UFU is among the lowest described in the literature, but there are still unnecessary prescriptions. Instruction and awareness of the assisting team can minimize these numbers.


RESUMO OBJETIVOS Avaliar a frequência da prescrição de inibidores da bomba de prótons (IBPs) e suas indicações em pacientes internados no Hospital de Clínicas da Universidade Federal de Uberlândia (HC-UFU). MÉTODOS Estudo observacional transversal quantitativo, análise de dados obtidos em prontuários sobre prescrições de IBPs para pacientes internados no HC-UFU, aplicação de questionário aos médicos assistentes sobre as indicações do medicamento em cada caso e avaliação dessas indicações com base em dados da literatura. RESULTADOS Em um dia predeterminado, de 462 pacientes internados, houve prescrição de IBP para 183 (39,3%), com maior frequência (73,5%) em Unidade de Terapia Intensiva (UTI), seguida das enfermarias e do pronto-socorro (PS). O médico assistente foi localizado em 116 casos, a principal motivação referida para prescrição foi a profilaxia de hemorragia digestiva (77%). Entretanto, após revisão de prontuários, percebeu-se que em 50,8% a prescrição não era respaldada por literatura. CONCLUSÃO A frequência de prescrição de IBP para pacientes internados no HC-UFU está entre as menores descritas na literatura, mas ainda há prescrições desnecessárias. Orientação e conscientização da equipe assistente podem minimizar esses números.


Subject(s)
Humans , Drug Prescriptions , Practice Patterns, Physicians' , Brazil , Cross-Sectional Studies , Proton Pump Inhibitors/therapeutic use , Tertiary Care Centers
19.
Einstein (Säo Paulo) ; 18: eAO4433, 2020. tab
Article in English | LILACS | ID: biblio-1056078

ABSTRACT

ABSTRACT Objective: To describe the pharmaceutical interventions of a vertical clinical pharmacy service to promote the rational use of intravenous omeprazole. Methods: A prospective and descriptive study carried out at a university hospital in the Midwestern Region of Brazil, from November 2014 to May 2015. The service consisted of the analysis of adequacy of the route of administration of omeprazole in relation to the clinical conditions of the patient, as well as the use of the appropriate diluent. Interventions were recorded in medical records and subsequently evaluated for acceptance. Results: A total of 770 prescriptions were evaluated. Interventions related to diluent replacement were more accepted (p<0.001), and surgeons were the specialty that used the intravenous route inappropriately (p<0.001). Conclusion: Although partially accepted, pharmaceutical interventions could contribute to improve patient safety, since they allowed the use of a safer route of administration.


RESUMO Objetivo: Descrever as intervenções farmacêuticas de um serviço farmacêutico clínico vertical, para a promoção do uso racional do omeprazol intravenoso. Métodos: Estudo prospectivo e descritivo realizado em um hospital universitário da região Centro-Oeste do Brasil, no período de novembro de 2014 a maio de 2015. O serviço consistia na análise da adequabilidade da via de administração do omeprazol em relação às condições clínicas do paciente, bem como a utilização do diluente adequado. As intervenções eram registradas em prontuário e, posteriormente, avaliadas quanto à aceitação. Resultados: Foram avaliadas 770 prescrições. As intervenções relacionadas à substituição do diluente foram mais aceitas (p<0,001), e os cirurgiões foram a especialidade que utilizou a via intravenosa de maneira inadequada (p<0,001). Conclusão: Embora parcialmente aceitas, as intervenções farmacêuticas puderam contribuir com a melhoria da segurança dos pacientes, uma vez que permitiram a utilização de uma via de administração mais segura.


Subject(s)
Humans , Male , Female , Adult , Aged , Pharmacy Service, Hospital/standards , Omeprazole/administration & dosage , Proton Pump Inhibitors/administration & dosage , Administration, Intravenous/methods , Drug Prescriptions/statistics & numerical data , Brazil , Prospective Studies , Sex Distribution , Age Distribution , Patient Safety , Hospitals, University , Medication Errors/statistics & numerical data , Middle Aged
20.
Rev. enferm. UFSM ; 10: 24, 2020.
Article in English, Portuguese | LILACS, BDENF | ID: biblio-1119007

ABSTRACT

Objetivo: identificar o conhecimento da pessoa com transtorno mental sobre o tratamento medicamentoso. Método: pesquisa observacional transversal desenvolvida com 300 pessoas em tratamento em dois Centros de Atenção Psicossocial de Curitiba, Paraná. Os dados foram coletados por entrevista estruturada e consulta à prescrição de medicamentos em prontuário. Foi realizada análise descritiva e inferencial. Resultados: a maioria dos participantes apresentou conhecimento insuficiente quanto ao nome dos medicamentos (64%), dose (91,9%) e frequência de administração (82,6%). Houve associação entre conhecimento insuficiente sobre a terapêutica medicamentosa e uso de medicamentos para comorbidades, desconhecimento do diagnóstico, depressão, idade avançada, autoadministração dos medicamentos, consumo de álcool e informações fornecidas pela enfermagem ou psicólogos. Conclusões: destaca-se que, principalmente, a autoadministração de medicamentos, transtornos depressivos e uso de medicamentos para outras condições de saúde podem estar relacionadas ao nível de conhecimento insuficiente da terapêutica medicamentosa, representando possíveis obstáculos a adesão e uso seguro dos medicamentos.


Objective: to identify knowledge about drug therapy among those people with mental illness. Method: cross-sectional observational research carried out with 300 people undergoing treatment at Psychosocial Care Centers in Curitiba, Paraná. Data were collected through structured interviews and by consulting prescriptions for medications in medical records. A descriptive and inferential analysis was performed. Results: the majority of participants had insufficient knowledge regarding the name of the drugs (64%), dose (91.9%) and frequency of administration (82.6%). There was an association between insufficient knowledge regarding drug therapy and the use of drugs for comorbidities, ignorance about the diagnosis, depression, advanced age, self-administration of drugs, alcohol consumption and misunderstanding information provided by nurses or psychologists. Conclusions: it is underscored that self-administration of medications, depressive disorders and use of medications for other health conditions may be related to the level of insufficient knowledge regarding their drug therapy; thus representing obstacles to adherence of medications.


Objetivo: identificar el conocimiento de la persona con trastorno mental sobre el tratamiento medicamentoso. Método: investigación observacional transversal desarrollada con 300 personas en tratamiento en Centros de Atención Psicosocial de Curitiba, Paraná. Los datos han sido recolectados por entrevista estructurada y consulta a la prescripción de medicamentos. Ha sido realizado análisis descriptivo e inferencia. Resultados: La mayoría de los participantes ha presentado conocimiento insuficiente cuanto al nombre de los medicamentos (64%), dosis (91,9%) y frecuencia de administración (82,6%). Ha habido asociación entre conocimiento insuficiente sobre la terapéutica y uso de medicamentos para comorbilidad, desconocimiento del diagnóstico, depresión, edad avanzada, auto-administración de medicamentos, consumo de alcohol e información provista por la enfermería o psicólogos. Conclusiones: Se destaca que la auto-administración de medicamentos, trastornos depresivos y uso de medicamentos para otras condiciones de salud pueden estar relacionadas al nivel de conocimiento insuficiente de la terapéutica medicamentosa, representando obstáculos de adhesión.


Subject(s)
Humans , Drug Prescriptions , Patient Medication Knowledge , Mental Disorders , Mental Health Services
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