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1.
Braz. j. biol ; 83: e243975, 2023. tab, graf
Article in English | LILACS, VETINDEX | ID: biblio-1285629

ABSTRACT

Abstract In South and South East Asia three genera of fish species i.e. Tor, Neolissochilus and Naziritor are commonly known as Mahseer with at least 47 species. Among these 23 belongs to genus Tor, 22 to Neolissochilus and one to Naziritor i.e. Naziritor zhobensis. Recently another species added to genus Naziritor is Naziritor chelynoides in India. Among Tor species Tor putitora (Hamilton) is the most widely distributed Mahseer in Pakistan and other countries of the Indian subcontinent. However, based alone on morphological characters some authors identify the Pakistani counterparts as Tor macrolepis (Heckel), (a species presumed to be found exclusively in the Indus River system) distinct from Tor putitora (a species found in Ganga Brahmaputra River system). In order to resolve this taxonomic ambiguity, present study carried out meristic and morphometric measurements of Mahseer collected from a total of 11 water bodies of Pakistan. Ratios between the morphometric characters were calculated and statistically analyzed using t-test and correlation coefficient. Two species identified as Tor putitora and Naziritor zhobensis were the sole Mahseer inhabitants of Indus system in Pakistan. Tor putitora occurred at all surveyed sites while Nazirtor zhobensis had a distribution range from river Zhob to tributaries of river Gomal the right bank tributaries of River Indus. The study corroborates that there are no unequivocal morphological synapomorphies in any existing populations of both species. The study further demonstrates that head length, a character frequently used in Mahseer taxonomy, is not a good measure for species identification. Finally the present study establishes that Naziritor zhobensis still exists in the water bodies of Pakistan and that golden Mahseer occurring in Indus riverine system of Pakistan is Tor putitora.


Resumo No sul e sudeste da Ásia, três gêneros de espécies de peixes, ou seja, Tor, Neolissochilus e Naziritor, são comumente conhecidos como Mahseer com pelo menos 47 espécies. Entre estas, 23 pertencem ao gênero Tor, 22 a Neolissochilus e um a Naziritor, ou seja, Naziritor zhobensis. Recentemente, outra espécie adicionada ao gênero Naziritor é Naziritor chelynoides na Índia. Entre as espécies de Tor, Tor putitora (Hamilton) é o Mahseer mais amplamente distribuído no Paquistão e em outros países do subcontinente indiano. No entanto, com base apenas em caracteres morfológicos, alguns autores identificam as contrapartes paquistanesas como Tor macrolepis (Heckel) (uma espécie que se presume ser encontrada exclusivamente no sistema do rio Indo), distinta de Tor putitora (uma espécie encontrada no sistema do rio Ganga Brahmaputra). A fim de resolver essas ambiguidades taxonômicas, o presente estudo realizou medidas merísticas e morfométricas de Mahseer coletadas em um total de 11 corpos d'água do Paquistão. As razões entre os caracteres morfométricos foram calculadas e analisadas estatisticamente usando o teste t e o coeficiente de correlação. Duas espécies identificadas como Tor putitora e Naziritor zhobensis foram os únicos habitantes Mahseer do sistema fluvial Indo no Paquistão. Tor putitora ocorreu em todos os locais pesquisados, enquanto Nazirtor zhobensis tinha uma faixa de distribuição do rio Zhob aos afluentes do rio Gomal, afluentes da margem direita do rio Indo. O estudo corrobora que não há sinapomorfias morfológicas inequívocas em nenhuma das populações existentes de ambas as espécies. O estudo demonstra ainda que o comprimento da cabeça, um caractere frequentemente usado na taxonomia de Mahseer, não é boa medida para identificação das espécies. Finalmente, o presente estudo estabelece que Naziritor zhobensis ainda existe nos corpos d'água do Paquistão e que o Mahseer dourado ocorrendo no sistema fluvial Indo do Paquistão é Tor putitora.


Subject(s)
Animals , Cyprinidae , Pakistan , India
2.
Braz. j. oral sci ; 21: e225388, jan.-dez. 2022. ilus
Article in English | LILACS, BBO | ID: biblio-1366211

ABSTRACT

Genetic and environmental factors are essential in occlusal variations and malocclusion and have been of considerable interest to orthodontists. Studies on twin pairs are one of the most effective methods for investigating genetically determined occlusal variables. Many studies have focused on distances between first molars or between canines but malocclusions can also occur in other regions of the dental arch. Aim: To evaluate the characteristics of the dental arch between pairs of Monozygotic (MZ) and Dizygotic (DZ) twins from Southern India. Methods: A random sample of 51 twin pairs (12­18years old) participated in this study. The zygosity of twin pairs was recorded by facial appearance. The occlusion of the first permanent molars was recorded according to Angle's classification. Study models were prepared to assess dental arch characteristics (i.e., arch form, arch perimeter, arch length; intercanine, intermolar width, and teeth size discrepancy). The obtained data was statistically analyzed using SPSS software 19.0. The student's t-test (two-tailed, independent) and Chi-square test was used to determine the significance of studied parameters. Results: Angle's Class I molar relation was more commonly observed followed by the Class II molar relationship among twins. The measured dental arch dimensions did not show a statistically significant difference among twin pairs. The ovoid arch form was commonly observed among Monozygotic and Dizygotic Twins. There was a similarity among MZ and DZ twins in the anterior and overall Bolton's ratio. Conclusion: There were similar occurrences of measured parameters among twins, which showed genetic predominance in the expression of measured dental arch traits


Subject(s)
Humans , Male , Female , Child , Adolescent , Twins, Dizygotic , Twins, Monozygotic , Dental Arch/anatomy & histology , India
3.
Rev. Assoc. Med. Bras. (1992) ; 68(2): 212-216, Feb. 2022. tab, graf
Article in English | LILACS | ID: biblio-1365352

ABSTRACT

SUMMARY OBJECTIVE: Neonates are more susceptible to drug interactions and adverse effects, and special care should be taken when prescribing medication to them. This study aimed to investigate drug usage in the neonatal intensive care unit of a tertiary care hospital. METHODS: This prospective observational study was conducted on 98 patients at the Apollo tertiary care hospital (Bannerghatta, Bangalore, India) in a period of 6 months. The most common indications for neonatal intensive care unit admission, average number of drugs per patient, the most frequently used medication, distribution of patients based on the birth procedure, and possible drug interactions were collected from patient profiles. RESULTS: Among the patients, 52% were males and 48% were females. Notably, 38% of patients were preterm, 60% were term, and only 2% were post-term. Also, 80.6% were born by cesarean section and 19.4% were born by normal vaginal delivery. The highest mean of drug use was in the patient of 1,000-1,500 g (8.06 per patient). Preterm was the most frequent indication for admission in neonatal intensive care unit, followed by hyperbilirubinemia and then respiratory distress syndrome. The most frequently used medication was vitamin K (99%) and antibiotics followed by dextrose. In different types of antibiotics, amikacin (41%), cefoperazone+sulbactam (35%), cephalosporin (1%), ceftriaxone (0.7%), and amoxicillin (0.3%) were commonly administered. There were some possible interactions, such as aminoglycoside with furosemide and calcium gluconate. CONCLUSION: Premature birth and resulting low birth weight were the main reasons for drug prescription. High administration of antibiotics is probably an area of concern and should be seriously considered.


Subject(s)
Humans , Male , Female , Pregnancy , Infant, Newborn , Intensive Care Units, Neonatal/statistics & numerical data , Drug Utilization/statistics & numerical data , Cesarean Section/adverse effects , Tertiary Care Centers/statistics & numerical data , India
4.
Article in English | LILACS, BBO | ID: biblio-1365223

ABSTRACT

Abstract Objective: To compare the Oncostatin M (OSM) concentrations in tissues of patients with chronic periodontitis with and without diabetes. Material and Methods: Sixty-four subjects visiting the dental outpatient department were categorized as "healthy" (Group 1), "periodontitis" (Group 2), and "diabetes with periodontitis" (Group 3) groups. The clinical oral examination included assessment of plaque, gingivitis, probing depth, clinical attachment level. Blood glucose was assessed for group 3 patients. OSM concentration in the tissues was assessed using ELISA in all groups. Results: The mean OSM was 0.02 ± 0.04 pg/mg in the healthy group, 0.12 ± 0.09 pg/mg in the chronic periodontitis group and 0.13 ± 0.10 pg/mg in the diabetes-periodontitis group. A significantly higher mean OSM was seen in Group 2 and Group 3 than Group 1. The amount of OSM positively correlated with probing depth and clinical attachment level. Conclusion: Periodontal disease causes a rise in Oncostatin M, independent of the diabetic status. Expression of OSM in the gingival tissues can serve as an inflammatory marker.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Dental Plaque Index , Cytokines , Diabetes Mellitus , Oncostatin M/analysis , Chronic Periodontitis/pathology , Periodontal Diseases , Blood Glucose , Chi-Square Distribution , Cross-Sectional Studies/methods , Analysis of Variance , Statistics, Nonparametric , Diagnosis, Oral , Gingiva , India/epidemiology , Inflammation
5.
Pesqui. bras. odontopediatria clín. integr ; 22: e210058, 2022. tab, graf
Article in English | LILACS, BBO | ID: biblio-1365226

ABSTRACT

ABSTRACT Objective To evaluate and compare the effect of 17% Ethylenediaminetetraacetic Acid (EDTA), 9% Etidronic acid (HEDP), and 7% Maleic acid (MA) on the push-out bond strength of NeoMTA Plus sealer to the coronal, middle, and apical thirds of root canal dentin. Material and Methods Forty single-rooted human maxillary central incisors were selected and decoronated to 12 mm long root fragments. Working length was established and root canals were then enlarged up to rotary Protaper F3. After each instrumentation, the root canal was irrigated with 2.5% NaOCl. For the final irrigation regimen, the specimens were divided into 4 groups (n=10) and treated with EDTA, HEDP, MA or Saline. Root canals were coated with NeoMTA Plus sealer, and obturation was done with single cone obturation technique. Subsequently, three horizontal sections were taken from the coronal, middle and apical thirds of each specimen, and POBS was measured using a universal testing machine. The type of bond failures was assessed under a stereomicroscope. Statistical analysis was done with One-way ANOVA with Tukey's Post hoc analysis. Results MA and EDTA showed the highest POBS. There was no significant difference in bond strength between MA and EDTA (p>0.05). HEDP and Saline showed lower POBS. Among all the four groups, the coronal third showed the highest values, followed by middle and apical thirds. Conclusion The type of chelating agent used during the root canal treatment significantly affects the bond strength of NeoMTA Plus to the root canal dentin.


Subject(s)
Humans , Root Canal Filling Materials , Tensile Strength , Chelating Agents/chemistry , Dental Cements , Endodontics , Analysis of Variance , Edetic Acid , Etidronic Acid , Dental Materials/chemistry , Incisor , India , Maleic Hydrazide
6.
Article in English | LILACS, BBO | ID: biblio-1365230

ABSTRACT

ABSTRACT Over the past year and a half dental education has been conducted primarily online due to the SARS-CoV-2 pandemic. During the pandemic, we have spent many hours a day on our computers, mobile phones, and tablets to gather information and participate in online seminars and classrooms. Health consequences resulting from the overuse of these devices include carpal tunnel syndrome as well as computer vision syndrome (CVS). Computer vision syndrome, also known as digital eye strain, has several associated features such as eye burning, strained vision, dry eye, blurred vision, and associated neck and shoulder pain. Several predisposing factors have been linked with CVS, but often this problem gets ignored. The management of this syndrome is aimed at educating dentists on computer use, position, and the surrounding environment. Considering all this, we must ensure that we spend some time away from these devices every day to avoid any significant vision problems. The objective of preparing this manuscript was to provide a brief overview of the increased prevalence of computer vision syndrome and its associated features.


Subject(s)
Vision Disorders/prevention & control , Artificial Intelligence , Dentists , Eye Diseases/prevention & control , COVID-19/complications , Microcomputers , Carpal Tunnel Syndrome , Prevalence , Risk Factors , Education, Dental , Screen Time , India
7.
Article in English | LILACS, BBO | ID: biblio-1365234

ABSTRACT

ABSTRACT Objective To evaluate the marginal adaptation of computer-aided designing and computer-aided machining (CAD/CAM) fabricated cobalt-chromium and zirconium-oxide-based ceramic crowns compared to those produced by a conventional method. Material and Methods The study consists of three groups; 45 crowns fabricated from cobalt-chromium (CAD-CoCr) and 45 crowns manufactured from zirconium CAD/CAM technology (CAD-Z), and 45 control (C) which consists of conventional metal-ceramic crowns. The marginal discrepancies in vertical dimensions were assessed utilizing a microscope in four surfaces (mesial, distal, vestibular, and oral) for each crown. On completion of the microscopic evaluation, multivariate analysis of variance (MANOVA) was used to study the difference in the four surfaces, considered altogether. Two-way ANOVA revealed the effect of three systems used for gap measurements of each landmark. The differences observed were considered significant at p<0.05. Results There were no differences in the four surfaces revealed by АNOVА in the three groups when considered altogether. Two-way ANOVA of each surface discovered no differences among all groups as well. Conclusion The CAD/CAM crowns revealed a comparable and satisfactory marginal adaptation compared to conventional metal-ceramic crowns.


Subject(s)
Zirconium , Chromium Alloys , Dental Prosthesis/instrumentation , Crowns , Dental Porcelain , In Vitro Techniques , Analysis of Variance , Metal Ceramic Alloys , Computer-Aided Design , Dental Marginal Adaptation , India
8.
Hematol., Transfus. Cell Ther. (Impr.) ; 43(3): 280-286, July-Sept. 2021. tab, ilus
Article in English | LILACS | ID: biblio-1346270

ABSTRACT

Abstract Introduction: Transfusion in cirrhotic patients remains a challenge due to the absence of evidence-based guidelines. Our study aimed to determine the indication of transfusion and the associated transfusion thresholds in cirrhotic patients. Methods: This retrospective observational study was conducted in the Department of Transfusion Medicine at a tertiary care liver center from October 2018 to March 2019. The blood bank and patient records of cirrhotic patients admitted during the study period were retrieved and analyzed to determine the current transfusion practice. Results: A total of 992 cirrhotic patients were included in the study. Blood components were transfused to 402 (40.5%) patients. Sixty-nine (17.2%) patients were transfused to control/treat active bleeding, while 333 (82.8%) were transfused prophylactically. Packed red blood cells (65.4%) was the most commonly transfused blood component, followed by fresh frozen plasma (35.6%), among patients receiving transfusions (therapeutic & prophylactic). The mean pre-transfusion thresholds for: (i) packed red blood cell transfusion: hemoglobin less than 7 g/dL; (ii) fresh frozen plasma transfusion: international normalized ratio over 2.6; (iii) platelet concentrate transfusion: platelet count less than 40,700/µL, and; (iv) cryoprecipitate transfusion: fibrinogen less than 110 mg/dL. The average length of stay of the study population was 5 days (3-9. Conclusion: To conclude, 40.5% of our hospitalized cirrhotic patients were transfused, with the majority of the transfusions being prophylactic (82.8%). Separate guidelines are required for this patient population, as these patients have an altered hemostasis which responds differently to the transfusion of blood components.


Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Blood Coagulation Disorders , Blood Transfusion , Liver Cirrhosis , India
9.
Invest. educ. enferm ; 39(2): [e12], 15 junio 2021. table 1, table 2, table 3, table 4
Article in English | LILACS, BDENF, COLNAL | ID: biblio-1254721

ABSTRACT

Objective. This study was carried out to examine professional and ethical values related to the profession from nurses' perspectives. Methods. This was a cross-sectional survey carried out among 124 randomly selected nurses working at a tertiary care hospital in South India. The data was collected using Nursing Professional Values scale (NPVS-3). This tool consisted of 28 items to assess nurses' professional values in three domains namely; Caring (10 items), activism(10items), and professionalism (8items). The maximum range of scores is 28­140. The higher the score, the stronger the nurse's professional value orientation. Results. The mean total score of the Professional Value scale was high (121.07±15.32). The mean score of the participants was higher in the caring domain (44.02±5.75) than activism (42.19±6.33) and professionalism domains (34.86±4.27). Pearson correlational analysis revealed that nurses with less experience had greater mean professional values score than nurses with higher experience (p<0.01). Conclusion. The present study showed that nurses have high professional and ethical values, although they perceive that the most important values are those related to direct patient care. Continuing education programs should be designed so that nurses understand that nonclinical professional values are also equally important in promoting the nursing profession


Objetivo. Este estudio se llevó a cabo para evaluar los valores profesionales y éticos relacionados con la profesión desde la perspectiva de los enfermeros. Métodos. Se trata de un estudio transversal realizado entre 124 enfermeras seleccionadas aleatoriamente quienes trabajan en un hospital de atención terciaria del sur de la India. Los datos se recogieron utilizando la escala de valores profesionales de enfermería (NPVS-3). Este instrumento consta de 28 ítems con respuesta tipo Likert de 1-5 que evalúa los valores profesionales de los enfermeros en tres dominios: cuidado (10 ítems), activismo (10 ítems) y profesionalismo (8 ítems). El rango máximo de las puntuaciones es de 28 a 140, cuanto mayor sea la puntuación, mayor será la orientación hacia los valores profesionales de enfermería. Resultados. La puntuación media total de la escala de valores profesionales fue alta (121.07±15.32). La puntuación media de los participantes fue más alta en el dominio de cuidado (44.02±5.75) que en el del activismo (42.19±6.33) y en el de profesionalismo (34.86±4.27). El análisis correlacional de Pearson reveló que las enfermeras con menos experiencia tenían una mayor puntuación media en valores profesionales que las enfermeras con mayor experiencia (p<0.01). Conclusión. El presente estudio mostró que las enfermeras tienen altos valores profesionales y éticos, aunque perciben que los valores más importantes son los relacionados con el cuidado directo al paciente. Deben diseñarse programas de formación continua para que las enfermeras comprendan que los valores profesionales no clínicos también son igualmente importantes para promover la profesión de enfermería


Objetivo. Este estudo foi realizado com o objetivo de avaliar os valores profissionais e éticos relacionados à profissão na perspectiva dos enfermeiros. Métodos. Este é um estudo transversal de 124 enfermeiras selecionadas aleatoriamente que trabalham em um hospital terciário no sul da Índia. Os dados foram coletados por meio da Nursing Professional Values Scale (NPVS-3). Esse instrumento é composto por 28 itens com resposta do tipo Likert de 1 a 5 que avaliam os valores profissionais do enfermeiro em três domínios: cuidado (10 itens), ativismo (10 itens) e profissionalismo (8 itens). A faixa máxima de pontuação é de 28 a 140, quanto maior a pontuação, maior a orientação para os valores do profissional de enfermagem. Resultados. A pontuação média total da escala de valores profissionais foi elevada (121.07±15.32). A pontuação média dos participantes foi maior no domínio cuidar (44.02±5.75) do que no ativismo (42.19±6.33) e no domínio profissionalismo (34.86±4.27). A análise correlacional de Pearson revelou que enfermeiras menos experientes tiveram uma pontuação média mais alta em valores profissionais do que enfermeiras mais experientes (p<0.01). Conclusão. O presente estudo mostrou que os enfermeiros possuem elevados valores profissionais e éticos, embora percebam que os valores mais importantes são aqueles relacionados ao cuidado direto ao paciente. Os programas de educação continuada devem ser planejados de forma que os enfermeiros entendam que os valores profissionais não clínicos também são igualmente importantes na promoção da profissão de enfermagem.


Subject(s)
Humans , Social Values , Cross-Sectional Studies , Ethics, Nursing , Professionalism , India
10.
Int. j. med. surg. sci. (Print) ; 8(2): 1-9, jun. 2021. tab, ilus
Article in English | LILACS | ID: biblio-1284417

ABSTRACT

Background:Lumbar sympathectomy through radio ablation is a useful treatment of peripheral ischemia. However, clinical efficacy with respect to lower limb ulcers is not adequately established in the Indian population. The study was conducted to evaluate the role of radiofrequency ablation (RFA) of the lumbar sympathetic ganglia in healing of ischemic ulcers of the lower limb.Method:The prospective study with 63 patients registered in the General surgery department with lower limb ischemic ulcers between December 2017­ July2019 were treated with RFA. Patients with cardiopulmonary disease, pregnant, congenital malformation, or skin infection at the site of intervention, or suffering from bleeding disorders, were excluded from the study. Clinical investigation of the wound was performed, and demographic data was collected. Comparative reduction in wound size was assessed through Friedman`s ANOVA (P<0.001). Difference in pain score, hospital stay, and walking distance were evaluated using Wilcoxon matched pair test (P<0.001), Unpaired t-test, and Paired t-test (P<0.05).Result:Majority of the patients were male (n=40) with a mean age of 60.93 SD14.34 years. Significant reduction in wound size, pain scores and hospital stay were observed post procedure(P<0.001). Number of RFA sessions was significantly associated with the size of the ulcer and Fontaine's classification 2 and 3 (P<0.0001).Conclusion:RFA of lumbar sympathetic ganglia is a potential treatment modality for lower limb ischemic ulcers.


Antecedentes: La simpatectomía lumbar a través de la ablación por radiofrecuencia es un tratamiento útil de la isquemia periférica. Sin embargo, la eficacia clínica con respecto a las úlceras en las extremidades inferiores no está adecuadamente establecida en la población india. El estudio se llevó a cabo para evaluar el papel de la ablación por radiofrecuencia (RFA) de los ganglios simpáticos lumbares en la curación de las úlceras isquémicas de la extremidad inferior. Método: El estudio prospectivo con 63 pacientes registrados en el departamento de cirugía general con úlceras isquémicas de las extremidades inferiores entre diciembre de 2017 y julio de 2019 fueron tratados con RFA. Los pacientes con enfermedad cardiopulmonar, malformación embarazada, congénita o infección de la piel en el lugar de la intervención, o que sufren de trastornos hemorrágicos, fueron excluidos del estudio. Se realizó una investigación clínica de la herida y se recopilaron datos demográficos. La reducción comparativa en el tamaño de la herida se evaluó a través del ANOVA de Friedman (P<0.001).Resultado: La diferencia en la puntuación del dolor, la estancia en el hospital y la distancia a pie se evaluaron mediante la prueba de par coincidente de Wilcoxon (P<0.001), la prueba t no emparejada y la prueba t emparejada (P<0.05). La mayoría de los pacientes eran varones (n-40) con una edad media de 60,93 SD14,34 años. Se observó una reducción significativa en el tamaño de la herida, las puntuaciones de dolor y la estancia hospitalaria (P<0.001). El número de sesiones de RFA se asoció significativamente con el tamaño de la úlcera y las clasificaciones 2 y 3 de Fontaine (P<0.0001).Conclusión: LA RFA de los ganglios simpáticos lumbares puede constituir una opción terapéutica para las úlceras isquémicas de las extremidades inferiores.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Ulcer/therapy , Lower Extremity , Radiofrequency Ablation/methods , Ganglia, Sympathetic , Ischemia/therapy , Prospective Studies , Analysis of Variance , India
11.
Ciênc. Saúde Colet ; 26(5): 1847-1852, maio 2021.
Article in English, Portuguese | LILACS | ID: biblio-1249504

ABSTRACT

Resumo O texto apresenta e discute os principais aspectos relacionados à dinâmica atual da indústria de vacinas no mundo e no Brasil, com foco na demanda criada pela pandemia da COVID-19. No plano global, expõe brevemente o lugar ocupado atualmente pelo Brasil no âmbito dos BRICS e expõe e analisa as opções - identidades e diferenças - da política industrial de Brasil, China e Índia no campo das vacinas. A seguir, analisa o deslocamento da indústria de vacinas de uma situação de produção exclusiva de imunizantes para um controle majoritário da grande indústria farmacêutica. Mais adiante, recupera aspectos fundamentais recentes da indústria de vacinas no Brasil, com ênfase em Biomanguinhos/Fiocruz e no Instituto Butantan. Finalmente, discute os sucessos e limitações do mecanismo de transferência de tecnologia utilizado pelas duas instituições, bem como a relevância do compromisso historicamente assumido pelas mesmas com as políticas públicas de saúde.


Abstract The text presents and discusses the main aspects related to the current dynamics of the vaccine industry in the world and in Brazil, focusing on the demand created by the pandemic of COVID-19. At the global level, it briefly exposes the place currently occupied by Brazil within the scope of the BRICS and sets out and analyzes the options - identities and differences - of industrial policy in Brazil, China and India in the field of vaccines. Next, it analyzes the displacement of the vaccine industry, from a situation of exclusive production of immunizers to a majority control by the large pharmaceutical industry. Further on, it recovers recent fundamental aspects of the vaccine industry in Brazil, with an emphasis on Biomanguinhos / Fiocruz and the Butantan Institute. Finally, it discusses the successes and limitations of the technology transfer mechanism used by the two institutions, as well as the relevance of their historically assumed commitment to public health policies.


Subject(s)
Humans , Vaccines , COVID-19 , Brazil , China , Public Health , SARS-CoV-2 , India
12.
Ciênc. Saúde Colet ; 26(4): 1419-1428, abr. 2021. tab
Article in English | LILACS | ID: biblio-1285924

ABSTRACT

Abstract The present study was an effort to assess the mitigation interventions carried out, so far, by the nations to fight the pandemic COVID-19. The novelty of the study was that it had considered the issue of pandemic mitigation strategy as a decision making problem. The performances of the twenty nations were to be ranked. The problem considered in the study was essentially a Multi-Criteria Decision Analysis (MCDA) problem. The available alternatives were the 20 countries and the 8 traits were the criteria. The Technique of Order Preference Similarity to the Ideal Solution (TOPSIS) was used in the present study. The study used Entropy method for assignment of weights to all the criteria. The performance score obtained in respect of the countries considered in the study and the corresponding ranks indicated the relative performances of the countries in their efforts to mitigate the COVID-19 pandemic. The results show that New Zealand is the best performing country and India is the worst one. Brazil ranked 17th, while the rank of UK was 15. The performance of the USA stood at 18th position.


Resumo O presente estudo foi um esforço para avaliar as intervenções de mitigação realizadas, até o momento, pelas nações para combater a pandemia COVID-19. A novidade do estudo é que considerou a questão da estratégia de mitigação da pandemia como um problema de tomada de decisão. As performances das vinte nações deveriam ser classificadas. O problema considerado no estudo era essencialmente um problema de Análise de Decisão Multi-Critério (MCDA). As alternativas disponíveis eram os 20 países e as 8 características eram os critérios. A Técnica de Similaridade de Preferência de Pedido com a Solução Ideal (TOPSIS) foi utilizada no presente estudo. O estudo utilizou o método da Entropia para atribuição de pesos a todos os critérios. A pontuação de desempenho obtida em relação aos países considerados no estudo e as classificações correspondentes indicaram os desempenhos relativos dos países em seus esforços para mitigar a pandemia COVID-19. Os resultados mostram que a Nova Zelândia é o país com melhor desempenho e a Índia o pior. O Brasil ficou em 17º, enquanto o Reino Unido ficou em 15. O desempenho dos EUA ficou na 18ª posição.


Subject(s)
Humans , Pandemics/prevention & control , COVID-19/prevention & control , United States/epidemiology , Brazil/epidemiology , Decision Support Techniques , Entropy , United Kingdom/epidemiology , India/epidemiology , New Zealand/epidemiology
13.
Rev. latinoam. bioét ; 21(1): 99-112, 2021.
Article in English | LILACS | ID: biblio-1341509

ABSTRACT

Abstract: The modern hospice movement, which is the origin of what is now known as palliative care, derived strong inspiration from Christianity. Given this original Christian inspiration, the global spread of palliative care even to countries where Christianity is only a minority religion may look surprising. In line with the theory of the "secularization of hospice," it could be argued that palliative care has spread globally because its underlying philosophy has become secular, allowing it to become universal. However, given the continuing importance of religion in many areas of palliative care, we could wonder how secular contemporary palliative care really is. This article argues that the universality of palliative care philosophy resides in its susceptibility to contextualization. Palliative care has become a global success story because people all over the world committed to palliative care's principles and ideas have contextualized these and developed models of palliative care delivery and even philosophy that are adapted to the local socio-economic and cultural-religious contexts. This article analyzes palliative care in India to illustrate this point, describing contextualized models of palliative care delivery and showing that palliative care physicians and nurses in India draw inspiration from their local context and religiosity.


Resumen: el movimiento moderno hospitalario, que es el origen de lo que ahora se conoce como cuidados paliativos, obtuvo una fuerte inspiración del cristianismo. Dada esta inspiración cristiana original, la propagación global de los cuidados paliativos incluso a países donde el cristianismo es sólo una religión minoritaria puede parecer sorprendente. En consonancia con la teoría de la "secularización de la hospitalización", se podría argumentar que los cuidados paliativos se han extendido globalmente puesto que su filosofía subyacente se ha vuelto secular, lo que le permite convertirse en universal. Sin embargo, dada la importancia continua de la religión en muchas áreas de los cuidados paliativos, podríamos preguntarnos cuán seculares son realmente los cuidados paliativos contemporáneos. Este artículo argumenta que la universalidad de la filosofía de cuidados paliativos reside en su susceptibilidad a la contextualización. Los cuidados paliativos se han convertido en una historia de éxito mundial, ya que personas de todo el mundo comprometidas con los principios e ideas de los cuidados paliativos los han contextualizado y han desarrollado modelos de prestación de cuidados paliativos e incluso una filosofía que se adapta al contexto socioeconómico y cultural-religioso local. Este artículo analiza los cuidados paliativos en la India para ilustrar este punto a través de modelos contextualizados de prestación de cuidados paliativos, y muestra que los médicos y enfermeras de cuidados paliativos en la India se inspiran en su contexto local y religiosidad.


Resumo: O movimento moderno hospitalar, que é a origem do que agora é conhecido como "cuidados paliativos", derivou de uma forte inspiragao do cristianismo. Tendo em vista essa inspiração cristã original, a propagação global dos cuidados paliativos, inclusive a países onde o cristianismo é somente uma religião minoritária, pode parecer surpreendente. Em consonância com a teoria da secularização da hospitalização, poderia argumentar-se que os cuidados paliativos vêm se estendendo globalmente, visto que sua filosofia subjacente vem se tornado secular, o que lhe permite converter-se em universal. Contudo, considerando a importância contínua da religião em muitas áreas dos cuidados paliativos, poderíamos perguntar-nos quão seculares são realmente os cuidados paliativos contemporáneos. Neste artigo, argumenta-se que a universalidade da filosofía de cuidados paliativos reside em sua suscetibilidade a contextualização. Os cuidados paliativos vêm se tornando uma história de sucesso mundial, já que pessoas de todo o mundo comprometidas com os princípios e as ideias dos cuidados paliativos os têm contextualizado e tem desenvolvido modelos de prestação de cuidados paliativos e inclusive uma filosofía que é adaptada ao contexto socioeconômico e cultural-religioso local. No texto, são analisados os cuidados paliativos na Índia para ilustrar esse ponto por meio de modelos contextualizados de prestação de cuidados paliativos e é mostrado que os médicos e os enfermeiros de cuidados paliativos na Índia se inspiram em seu contexto local e em sua religiosidade.


Subject(s)
Humans , Palliative Care , Religion , Bioethics , Christianity , India
14.
Article in English | LILACS, BBO | ID: biblio-1287486

ABSTRACT

ABSTRACT Objective: To compare the detection rate of root canal orifices of maxillary first molar by various techniques in the Indian population. Material and Methods: A total of 50 maxillary 1st molar cases were selected and sequentially divided into four groups: Group I: Naked eye; Group II: Surgical loupe; Group III: Surgical operating microscope; and Group IV: Fluorescein sodium dye. After access opening, the number of root canal orifices was detected in all cases with these methods. Results: By naked eye and surgical loupe, a total of 171 root canal orifices were detected, by a surgical operating microscope, 176, and by fluorescein sodium dye, 177 root canal orifices were detected. The detection rate of root canal orifices is as follows: Group I (96.61%) = Group II (96.61%) < Group III (99.44%) < Group IV (100%) and detection rate of MB-2 canal orifices Group I (40%) = Group II (40%) < Group III (50%) < Group IV (52%). No significant difference in the number of canal orifices detected could be seen for any of the comparisons. No significant difference was observed between the naked eye and surgical loupe techniques. Although the surgical operating microscope detected more root canal orifices, it did not have a significantly higher detection than the other two techniques. Conclusion: No significant difference was seen among various methods. However, the use of a surgical operating microscope and fluorescein sodium dye increased the detection rate of root canal orifices.


Subject(s)
Humans , Root Canal Therapy/instrumentation , Fluorescein , Dental Caries/diagnosis , Endodontics , Molar , Chi-Square Distribution , Clinical Diagnosis , Data Interpretation, Statistical , Diagnostic Techniques and Procedures , Endodontists , India
15.
Article in English | LILACS, BBO | ID: biblio-1287485

ABSTRACT

ABSTRACT Objective: To establish the validity of COVID-19 Peritraumatic Distress Index (CPDI) questionnaire and assess the stress with its associated factors during COVID-19 among dental professionals in Bhubaneswar, India. Material and Methods: An online survey through Google Forms was steered among 234 dentists. CPDI questionnaire was used for data collection post its validation assessment. Content validity was judged satisfactory by two psychiatrists, and excellent internal consistency was found (Cronbach's alpha = 0.92). For statistical analysis, chi-square and binomial logistic regression tests were used with a significance level of p=0.05. Results: 70 (29.9%) were males and 164 (70.1%) were females with a mean age of 30.58 ± 6.70 years. Around 50% had an MDS degree and were attached to an institution and nearly 80% were having experience of less than 10 years. The mean CPDI score was found to be 29.09 ± 15.47. A statistically significant association was observed between CPDI scores with age (p<0.003), gender (p<0.03), practice (p<0.06) and education (p<0.006). Binomial logistic regression revealed that odds of stress were 2 times higher among males than females (OR=2.01, p<0.04), which was statistically significant. Conclusion: Acceptable validation scores confirmed CPDI as an effective instrument for detecting stress. Importance of early interventions to combat the issue of stress among dental professionals as it is allied with negative consequences on health and furthermore affects daily activities is highlighted.


Subject(s)
Humans , Male , Female , Health Personnel , Dentists , Pandemics , COVID-19 , India/epidemiology , Psychiatry , Chi-Square Distribution , Logistic Models , Cross-Sectional Studies/methods , Surveys and Questionnaires
16.
Article in English | LILACS, BBO | ID: biblio-1287482

ABSTRACT

ABSTRACT Objective: To evaluate the efficacy of pre-cooling and the use of higher gauged needles in reducing pain during local anesthetic infiltration. Material and Methods: We conducted a split-mouth randomized controlled trial among 70 patients who require bilateral maxillary local anesthetic (LA) injections for dental treatment. After applying the topical anesthetic, each participant received four local anesthetic injections, two on buccal and two palatal sides. At each visit, the participants received one buccal and one palatal infiltration based on the randomization. On the buccal aspect, participants received LA with a 26G needle injection on one side (control) and a 31G needle (test) on the contralateral side. On the Palatal aspect, participants either received LA with a 31G needle on one side (control). In contrast, the opposite side was preceded by topical ice application (iced cotton swab) before LA with a 31G needle (test). Both the visits were spaced with a gap of 7-10 days based on the participants' feasibility. Participants were asked to rate the pain on a visual analog scale independently for buccal and palatal LA injections. Results: On the Buccal aspect, the mean pain scores were 2.74 ± 1.26 and 2.11 ± 1.26 for control and test groups, respectively (p=0.002). On the Palatal aspect, the mean pain scores were 4.14 ± 1.49 and 4.3 ± 1.80 for control and test groups, respectively (p=0.295). Conclusion: Significant lower pain scores were reported with higher gauge needles (31G) when compared to traditional (26G) needles on the buccal aspect. No significant difference was seen with pre-cooling the injection site on the palatal aspect when used with higher gauged needles (31G).


Subject(s)
Humans , Male , Female , Adult , Pain , Pain Measurement/instrumentation , Dental Anxiety/psychology , Visual Analog Scale , Anesthesia, Local/instrumentation , Efficacy , Analysis of Variance , Data Interpretation, Statistical , Randomized Controlled Trial , Cold Temperature/methods , India , Mouth , Needles
17.
Article in English | LILACS, BBO | ID: biblio-1250463

ABSTRACT

ABSTRACT Objective: To evaluate in vitro the flexural strength of two newer composite resin materials. Material and Methods: Twenty-four samples were equally divided into two groups: G1 - Brilliant EverGlow and G2: Brilliant NG. The rectangular blocks of 25 mm in length, 2 mm in width and thickness were prepared from two composite materials. Blocks were created by applying composites to a customized split mold and formed between two parallel glass plates. Before light-curing, blocks were covered with Mylar strips and rinsed for 10 seconds in water. Subsequently, they were stored in distilled water for 24 hours at 37ºC and 100% humidity before testing. Each sample was placed within a suitable framework of aluminum. The length of gap between the support was 21 mm and the speed of crosshead at 1 mm/minute. The data were subjected to an independent t-test. The level of significance was set at p <0.05. Results: A less flexural strength was observed in G1 (77.43 Mpa) compared to G2 (118.70 Mpa) (p<0.001). Conclusion: Universal nanohybrid composite resin material was found to have greater flexural strength than universal submicron hybrid composite material.


Subject(s)
Materials Testing , Composite Resins , Dental Materials , Nanocomposites , Flexural Strength , In Vitro Techniques/methods , Data Interpretation, Statistical , Light-Curing of Dental Adhesives/methods , India
18.
Article in English | LILACS, BBO | ID: biblio-1250461

ABSTRACT

ABSTRACT Objective: To evaluate and compare lipid profile level in oral submucous fibrosis (OSMF), oral leukoplakia (OL) and oral squamous cell carcinoma (OSCC) patients. Material and Methods: Thirty histopathologically diagnosed subjects each of OL, OSMF, OSCC were recruited along with 30 healthy controls. 5ml of venous blood is collected and estimated using standard diagnostic kits. Results: The mean of Total cholesterol level in controls was 219.03 mg%, in OSCC, OL and OSMF was 142.89 ± 10.21mg%, 155.44 ± 17.63 mg% and 180.60 ± 13.25 mg%, respectively. The mean low-density lipid level in controls was 137.24 mg and in OSCC, OL and OSMF groups were 109.28 ± 2.16 mg%, 126.63 ± 0.85 mg% and 119.15 ± 0.93 mg%, respectively. The mean of high-density lipid level in controls, OSCC, OL and OSMF was 42.87 ± 0.42 mg%, 36.50 ± 2.31 mg%, 21.13 ± 0.77 mg% and 28.37 ± 1.11mg%, respectively. The mean of very low density lipids level in controls, OSCC, OL and OSMF was 30.12 ± 1.51 mg%, 17.24 ± 0.80 mg%, 22.25 ± 0.93 mg% and 25.89 ± 0.43 mg%, respectively. The mean triglyceride level in controls, OSCC, OL and OSMF was 118.80 ± 9.47 mg%, 91.2 ± 3.03 mg%, 105.05 ± 2.96 mg% and 106.19 ± 3.09 mg%, respectively. Conclusion: Lipid profile levels could be early indicators of precancer and cancer.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Oral Submucous Fibrosis/pathology , Leukoplakia, Oral/pathology , Mouth Neoplasms , Carcinoma, Squamous Cell/pathology , Indicators and Reagents , Lipids , Analysis of Variance , Data Interpretation, Statistical , India , Lipoproteins, HDL , Lipoproteins, LDL , Lipoproteins, VLDL
19.
Article in English | LILACS, BBO | ID: biblio-1143402

ABSTRACT

ABSTRACT Objective: To assess the current level of oral health knowledge and identify information sources among adolescents in Bhubaneswar, India. Material and Methods: A cross-sectional examination was conducted among 1330 adolescents aged 13 to 15 years enrolled in 24 randomly selected government and private schools in Bhubaneswar. A specially designed self-administered questionnaire was used to collect the responses. Chi-square test with a level of significance set at 5% was used for statistical analysis. Results: Parents (55%) followed by media (18%) were the major sources of oral health information among the study population, which was statistically not significant in relation to gender and school type. Many subjects (95.3%) perceived sweets could cause tooth decay; however, this was statistically significant only among school type (p<0.05). Around (45%) knew about fluoride and only 36% properly identified fluoride's action as preventing cavities. This was statistically significant among both gender and school type (p<0.05). Seventy-five percent of students effectively distinguished gum disease symptoms, which was significant only with gender (p<0.05). Around 55% identified that oral habits have an influence on oral health, which showed significance among gender (p<0.05). Conclusion: Children oral health knowledge was not satisfactory, highlighting the need to utilize parents, schoolteachers and media to provide oral health education. It's essential for designing and implementing a person-centered care model in dentistry.


Subject(s)
Humans , Male , Female , Adolescent , Health Knowledge, Attitudes, Practice , Oral Health/education , Adolescent , Dental Care , India/epidemiology , Chi-Square Distribution , Cross-Sectional Studies/methods , Surveys and Questionnaires
20.
Article in English | LILACS, BBO | ID: biblio-1346679

ABSTRACT

ABSTRACT Objective: To evaluate the effectiveness of oil pulling in the management of oral submucous fibrosis (OSMF). Material and Methods: A total of 62 patients clinically and histopathologically diagnosed as OSMF were incorporated in the present study. The subjects are randomly divided equally into two groups, Group A (oil pulling group) and Group B (placebo group). Subjects in Group A were asked to perform OP with sesame oil on an empty stomach in the morning for 3 months and Group B was given placebo capsules for 3 months. Assessment of various clinical parameters was done regularly, and data were analyzed using the Chi-square test. Results: Eighty-two percent had a habit of betel nut chewing, while 18% of the patients had tobacco chewing habits, which were among the main causative factors for OSMF. Clinical improvements in mouth opening, tongue protrusion, difficulty in speech and deglutition, and burning sensation were significant in the Group A. None of the patients reported any discomfort or side effects. The symptoms were not severe in nature and resolved in few days without stopping the therapy. Conclusion: Oil pulling can bring about significant clinical improvements in the symptoms like a mouth opening and tongue protrusion.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Oral Submucous Fibrosis/pathology , Precancerous Conditions/pathology , Therapeutics , Effectiveness , Sesame Oil , Chi-Square Distribution , Visual Analog Scale , India/epidemiology
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