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1.
Infectio ; 25(4): 262-269, oct.-dic. 2021. tab, graf
Article in English | LILACS, COLNAL | ID: biblio-1286720

ABSTRACT

Abstract Objective: To analyse the clinic characteristics, risk factors and evolution of the first cohort of hospitalised patients with confirmed infection by COVID-19 in 5 Colombian institutions. Materials and methods: Is a retrospective observational study of consecutive hospitalized patients with a diagnosis of COVID-19 confirmed from March 01 to May 30, 2020 in Colombia. Results: A total of 44 patients were included. The median age was 62 years. 43.2% had a history of smoking, while 69.8% were overweight or obese. 88.6% had at least one comorbidity and 52.3% had three or more comorbidities. Hypertension and dyslipidaemia were the most frequent comorbidities (40.9% and 34.1%, respectively). The 30-day mortality rate was 47.7% with a median of 11 days. The composite outcome occurred in the 36.4%. The biomarkers associated with mor tality risk included troponin higher than 14 ng/L (RR: 5.25; 95% CI 1.37-20.1, p = 0.004) and D-dimer higher than 1000 ng/ml (RR: 3.0; 95% CI 1.4-6.3, p = 0.008). Conclusions: The clinical course of SARS-CoV-2 infection in hospitalized Colombian was characterised by a more advanced stage of the infection.


Resumen Objetivo: Analizar las características, clínicas, factores de riesgo, y la evolución de pacientes hospitalizados con infección confirmada por COVID-19 en 5 Institu ciones de Colombia. Material y método: Es un estudio observacional retrospectivo de pacientes consecutivos hospitalizados con diagnóstico de COVID-19 confirmado entre 01 de Febrero de 2020 y 30 de Mayo de 2020 en Colombia. Resultados: Un total de 44 pacientes fueron incluidos. La mediana de edad fue de 62 años y la mayoría del sexo masculino. El 43.2% tenían historia de tabaquismo, mientras que el 69.8% tenían sobrepeso u obesidad. El 88.6% tenían al menos una comorbilidad y el 52.3% tenían tres o más comorbilidades. La hipertensión arterial fue la comorbilidad más frecuente (40.9%), seguido de la dislipidemia (34.1%). La tasa de letalidad a 30 días fue de 47.7% y ocurrió con una mediana de 11 días. El 36.4% presentó el desenlace compuesto. Los biomarcadores asociados con el riesgo de muerte fue troponina > 14 ng/mL (RR:5.25, IC95% 1.37-20.1, p=0.004) y dímero D mayor a 1000 mg/dL (RR: 3.0, IC95% 1.4-6.3, p=0.008). Conclusiones: El curso clínico de la infección por SARS-CoV-2 en colombianos hospitalizados fue un estadio más avanzado de la infección.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , Biomarkers , COVID-19 , Patients , Tobacco Use Disorder , Comorbidity , Risk , Risk Factors , Mortality , Colombia , Overweight , Courses , Infections , Obesity
2.
Braz. j. oral sci ; 20: e211359, jan.-dez. 2021. ilus
Article in English | LILACS, BBO | ID: biblio-1252506

ABSTRACT

Aim: To evaluate the effects of an intervention for the prevention of obesity on the prevalence of dental caries disease in Spanish children. Methods: Two cities participated intervention study nested in a cohort IDEFICS (Identification and prevention of dietary and lifestyle induced health effects in children and infants): Huesca, where there was a 2-year intervention, which encouraged less sugar consumption; and Zaragoza (control). The prevalence of caries was evaluated by examining the 1st permanent molars in the 7-11 age range, using the ICDAS (International Caries Detection and Assessment System). These teeth erupt at 6 years of age and at the baseline (2007-2008) were free of caries because they were not present in the oral cavity. As outcomes, white spots were selected, combining the ICDAS criteria 1 and 2, and untreated caries, combining criteria 4, 5 and 6. Their association with socioeconomic variables, BMI (Body Mass Index), frequency of sugar intake, sex and parents' perceptions of their children, was investigated. To do so, the chi-square test was applied (p<0.05). Results: The sample consisted of 281 children. The prevalence of white spots and untreated caries was higher in Huesca, despite the intervention. There was no association between the outcomes and the variables studied (p>0.05). Conclusion: The intervention for the prevention of obesity did not exert any association with the prevalence of caries in Spanish children


Subject(s)
Humans , Male , Female , Child , Oral Health , Dental Caries/epidemiology , Obesity
3.
Vínculo ; 18(2): 1-6, jul.-dez. 2021. ilus
Article in Portuguese | LILACS, INDEXPSI | ID: biblio-1341802

ABSTRACT

Muitos são os problemas orgânicos ou psíquicos que surgem em indivíduos obesos. Diante desse mal-estar gerado pela obesidade, as angústias são relatadas com frequência por pacientes em discursos que giram em torno da alimentação e do corpo, carregados de frustrações que remetem a dietas fracassadas para dar conta da supervalorização de um corpo ideal na sociedade contemporânea. Nesse sentido, foi percebido nos relatos clínicos uma repetição, um ciclo vicioso que os pacientes têm dificuldade de interromper. Grande parte desses sujeitos relataram, nos atendimentos em grupo e individuais, que têm a comida como substituto de "algo", de um "vazio" que precisa ser preenchido, pois comem mesmo sem estarem com fome e com uma sensação de perda do controle sobre o ato. Por essa razão, após esse comportamento repetitivo, têm sentimentos de raiva, vergonha e culpa. Este artigo tem por objetivo investigar o mal-estar observado nas pessoas obesas atendidas individualmente na clínica particular e na instituição privada, bem como nos atendimentos realizados em grupo. Busca-se conhecimentos acerca da angústia em relação ao corpo obeso, com vistas a fomentar discussões embasadas pela orientação psicanalítica, utilizando durante os atendimentos a metodologia freudiana e a balintiana no atendimento de grupo.


Many are the organic or psychic problems that arise in obese individuals. Faced with this discomfort generated by obesity, anxieties are frequently reported by patients in discourses that revolve around diet and the body, loaded with frustrations that refer to failed diets to cope with the overvaluation of an ideal body in contemporary society. In this sense, it was perceived in clinical reports a repetition, a vicious cycle that patients have difficulty interrupting. Most of these subjects reported, in group and individual care, that they have food as a substitute for "something", a "void" that needs to be filled, because they eat even without being hungry and with a sense of loss of control over the act. For this reason, after this repetitive behavior, they have feelings of anger, shame and guilt. This article aims to investigate the discomfort observed in obese people treated individually in the private clinic and private institution, as well as in group care. Knowledge about anguish in relation to the obese body is sought, in order to foster discussions based on psychoanalytic orientation, using the Freudian and Balintian methodology during group care


Muchos son los problemas orgánicos o psíquicos que surgen en personas obesas. Frente a este malestar generado por la obesidad, los pacientes informan con frecuencia ansiedades en discursos que giran en torno a la dieta y el cuerpo, cargados de frustraciones que conducen a dietas fallidas para hacer frente a la sobrevaloración de un cuerpo ideal en la sociedad contemporánea. En este sentido, se percibió en los informes clínicos una repetición, un círculo vicioso que los pacientes tienen dificultades para interrumpir. La mayoría de estos sujetos informaron, en atención grupal e individual, que tienen comida como un sustituto de "algo", un "vacío" que necesita ser llenado, porque comen incluso sin tener hambre y con una sensación de pérdida de control sobre el acto Por esta razón, después de este comportamiento repetitivo, tienen sentimientos de ira, vergüenza y culpa. Este artículo tiene como objetivo investigar las molestias observadas en personas obesas tratadas individualmente en la clínica privada y la institución privada, así como en la atención grupal. Buscamos conocimiento sobre la angustia con respecto al cuerpo obeso, para fomentar discusiones basadas en la orientación psicoanalítica, utilizando durante la metodología freudiana y balintiana en la atención grupal.


Subject(s)
Humans , Anxiety , Bulimia , Hunger , Diet , Emotions , Binge-Eating Disorder , Body Dissatisfaction , Obesity
4.
Rev. ADM ; 78(5): 264-269, sept.-oct. 2021. tab, graf
Article in Spanish | LILACS | ID: biblio-1348067

ABSTRACT

Introducción: La mucina salival (Ms) modula otras proteínas salivales que participan en múltiples funciones fisiológicas de la cavidad oral. Los niveles de Ms pueden proporcionar información sobre el estado de inflamación de los tejidos periodontales. Por tanto, el objetivo del presente estudio fue evaluar los niveles Ms en pacientes obesos y no obesos, antes y después del tratamiento periodontal. Material y métodos: Un total de 60 pacientes fueron distribuidos en seis grupos, de acuerdo al índice de masa corporal (IMC) y la gravedad de la enfermedad periodontal (EP). Valores del IMC superiores a 27 correspondían a obesidad. La EP en el momento del diagnóstico se designó como leve, moderada o severa. Se recolectaron muestras de saliva completa, antes (MU-A) y después (MU-D) del tratamiento periodontal. Se evaluaron los niveles de Ms utilizando el método de Azul Alcian. Los resultados se analizaron con el Software InfoStat, mediante estadística descriptiva e inferencial. Resultados: Los valores de MU-A fueron superiores a los contenidos de MU-D (p < 0.0001). Las variaciones entre los pacientes no obesos y obesos fueron mínimas. A medida que aumentó el nivel de la EP, las variables MU-A y MU-D mostraron una disminución progresiva (p = 0.0032). Conclusiones: El nivel de Ms fue mayor en la saliva de los pacientes con EP no tratada. Ms se puede utilizar como marcador inflamatorio para la detección de EP (AU)


Introduction: Salivary mucin (sM) modulates other salivary proteins that participate in multiple physiological functions of the oral cavity. sM levels can provide information on the state of inflammation of the periodontium. Therefore, the objective of the present study was to evaluate sM levels in obese and non-obese patients, before and after periodontal treatment. Material and methods: A total of 60 patients were distributed into six groups, according to the body mass index (BMI) and the severity of the periodontal disease (PD). BMI values higher than 27 corresponded to obesity. PD at the time of diagnosis was designated as mild, moderate, or severe. Complete saliva samples were collected before (MU-B) and after (MU-A) the periodontal treatment. sM levels were evaluated using the Alcian Blue method. The results were analyzed with the InfoStat Software, using descriptive and inferential statistics. Results: MU-B values were higher than MU-A contents (p < 0.0001). Variations between non-obese and obese patients were minimal. As the level of PD increased, the variables MU-A and MU-D showed a progressive decrease (p = 0.0032). Conclusions: The level of sM was higher in the saliva of patients with untreated PD. sM can be used as an inflammatory marker for the detection of PD (AU)


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Periodontal Diseases , Saliva , Mucins/analysis , Obesity/complications , Argentina , Schools, Dental , Biomarkers , Epidemiology, Descriptive , Statistical Analysis , Alcian Blue , Controlled Before-After Studies
5.
Ludovica pediátr ; 24(1): 15-24, Ene-Jun 2021.
Article in Spanish | LILACS, Redbvs, BINACIS | ID: biblio-1293219

ABSTRACT

Introducción: El puerperio es una etapa determinante para la mujer, sin embargo la atención está focalizada en el recién nacido. Objetivo: Describir las características gineco-obstétricas, nutricionales y clínico-metabólicas de mujeres durante el posparto que asisten al consultorio materno del Instituto de Desarrollo e Investigaciones Pediátricas. Población y Métodos: Se realizó un análisis retrospectivo de las historias clínicas de mujeres que realizaron su primer control entre los 3 y 6 meses posparto en un consultorio materno de un hospital público entre junio 2018 y diciembre 2019. Se analizaron variables sociodemográficas, gineco-obstétricas, nutricionales y clínico-metabólicas. Resultados: Participaron 211 mujeres, edad 26 (21; 31) años, 41,7 % oriundas de países limítrofes. 38,8 % tuvo un embarazo durante la adolescencia, 38,7 % de los partos fue por cesárea y 21,3 % refirió antecedentes de aborto Más de la mitad presentaron sobrepeso-obesidad y alteraciones del perfil lipídico Conclusiones: Las mujeres asistidas durante el postparto en un hospital público presentan alta frecuencia de exceso de peso y alteraciones metabólicas así como historial de cesáreas y embarazo adolescente. El conocimiento de las problemáticas más prevalentes es clave para el diseño de estrategias de prevención e intervenciones oportunas


Introduction: The puerperium is a determining stage for women, however, attention is focused on the newborn. Objective: To describe the gyneco-obstetric, nutritional and clinical-metabolic characteristics of postpartum women who attend the IDIP maternal clinic. Population and methods: A retrospective analysis was carried out of the medical records of women who underwent their first check-up between 3 and 6 months postpartum in a maternal clinic of a public hospital between June 2018 and December 2019 Sociodemographic, gynecological, nutritional, and clinical-metabolic variables were analysed. Results: 211 women participated, age 26 (21; 31) years old, 41.7% from neighbouring countries, 38.8% had a pregnancy during adolescence, 38.7% of deliveries were by caesarean section, and 21.3% reported a history of abortion. More than half presented overweight-obesity and lipid profile alterations. Conclusions: The women assisted during the postpartum in a public hospital present a high frequency of excess weight and metabolic alterations as well as a history of caesarean sections and adolescent pregnancy. Knowledge of the most prevalent problems is key for the design of prevention strategies and timely interventions


Subject(s)
Humans , Female , Postpartum Period , Maternal Nutrition , Maternal Health , Obesity
6.
SOBECC ; 26(3): 156-164, 30-09-2021.
Article in Portuguese | LILACS, BDENF | ID: biblio-1342654

ABSTRACT

: Objetivo: Identificar os diagnósticos de Enfermagem da North American Nursing Diagnosis Association (NANDA Internacional) nos pacientes no pós-operatório de cirurgia bariátrica e relacioná-los com problemas adaptativos propostos por Roy. Método: Estudo exploratório, a partir da técnica de multicasos, realizado em hospital de referência em cirurgias bariátricas no estado do Ceará, no período de novembro a dezembro de 2018. A coleta de dados ocorreu por meio de entrevistas e do exame físico em que se utilizou instrumento estruturado com os quatro modos adaptativos de Roy. Resultados: Neste estudo, foram identificados 21 diagnósticos de Enfermagem, que estiveram ligados aos problemas adaptativos respiração prejudicada, dificuldade para vestir-se, nutrição, sedentarismo, padrão de sono, mastigação, controle da obesidade, baixa autoestima, interação social, organismo saudável, ansiedade, autocuidado, satisfação com aparência, espiritualidade, relacionamento saudável, conhecimento e comunicação. Conclusão: Predominaram diagnósticos de Enfermagem de bem-estar, o que sugere que a realização da cirurgia bariátrica e os resultados obtidos, como perda de peso, aumento da disposição e melhora do estado de saúde, influenciam positivamente no processo de adaptação pós-cirurgia.


: Objective: To identify the nursing diagnoses of the North American Nursing Diagnosis Association (NANDA International) in patients who underwent bariatric surgery, during the postoperative period, and their relation to adaptation problems according to the Roy Adaptation Model. Method: This is an exploratory, multicase study carried out in a reference hospital for bariatric surgeries in the state of Ceará, Brazil, from November to December 2018. Data collection took place through interviews and physical examination using a structured instrument with the four modes of adaptation of the Roy Adaptation Model. Results: In this study, 21 nursing diagnoses were identified, which were related to the following adaptation problems: impaired breathing, difficulty dressing up, nutrition, sedentary lifestyle, sleep pattern, chewing, obesity control, low self-esteem, social interaction, healthy organism, anxiety, self-care, satisfaction with appearance, spirituality, healthy relationship, knowledge, and communication. Conclusion: Wellness nursing diagnoses predominated, which suggests that the performance of bariatric surgery and the obtained results, such as weight loss, increased disposition, and improved health status, positively influence the postoperative adaptation process.


Objetivo: Identificar los Diagnósticos de Enfermería Internacional NANDA en pacientes en el postoperatorio de cirugía bariátrica y relacionarlos con problemas adaptativos del Modelo de Adaptación de Roy. Método: Estudio exploratorio, mediante la técnica multicase, realizado en un hospital de referencia en cirugías bariátricas en el Estado de Ceará, de noviembre a diciembre de 2018. La recolección de datos se realizó a través de entrevistas y examen físico en el que utilizó instrumento adaptado estructurado con los cuatro modos adaptativos de Roy. Resultados: Se identificaron 21 Diagnósticos de Enfermería, los cuales se relacionaron con problemas adaptativos, dificultad para respirar, dificultad para vestirse, nutrición, sedentarismo, patrón de sueño, masticación, control de la obesidad, baja autoestima, interacción social, organismo sano, ansiedad, autocuidado, satisfacción con la apariencia, espiritualidad, relación sana, conocimiento y comunicación. Conclusión: Predominaron los diagnósticos de enfermería de bienestar, lo que sugiere que la realización de la cirugía bariátrica y los resultados obtenidos, como la pérdida de peso, mayor disposición y mejor estado de salud, influyen positivamente en el proceso de adaptación posquirúrgico.


Subject(s)
Humans , Postoperative Period , Nursing Diagnosis , Bariatric Surgery , Perioperative Nursing , Perioperative Period , Obesity
7.
Arq. gastroenterol ; 58(3): 316-321, July-Sept. 2021. tab
Article in English | LILACS | ID: biblio-1345286

ABSTRACT

ABSTRACT BACKGROUND AND OBJECTIVE: Considering the association between colorectal cancer (CRC) and both insulin resistance and obesity, and the prominent role of ghrelin in these metabolic disorders, we explored whether plasma levels of ghrelin were associated with CRC. Moreover, in the patients with CRC the possible correlations between ghrelin and insulin, insulin resistance, and body mass index (BMI) as an indicator of obesity were examined. METHODS: A total of 170 subjects, including 82 cases with CRC and 88 controls were enrolled in this study. Plasma levels of ghrelin, insulin, and glucose were measured in all the subjects using ELISA and glucose oxidase methods. Furthermore, insulin resistance was assessed by calculating HOMA-IR index. RESULTS: The cases with CRC had decreased ghrelin levels (P<0.001) and a higher HOMA-IR index (P<0.001) than controls. Interestingly, when CRC patients were stratified based on tumor site, lower ghrelin levels and a higher HOMA-IR index were observed in the patients with either colon or rectal cancer vs. controls too. Additionally, there were an age and BMI-independent negative correlation between ghrelin levels and HOMA-IR (r=-0.365, P<0.05), and an age-independent negative correlation between ghrelin levels and BMI (r=-0.335, P<0.05) in the rectal subgroup. CONCLUSION: Our findings support a role for ghrelin in connection with insulin resistance and obesity in CRC susceptibility; however, it needs to be corroborated by further studies.


RESUMO CONTEXTO E OBJETIVO: Considerando a associação entre câncer colorretal (CCR), a resistência à insulina, à obesidade e o papel proeminente da grelina nessas doenças metabólicas, foi explorado se os níveis plasmáticos de grelina estavam associados ao CCR. Além disso, nos pacientes com CCR foram pesquisadas as possíveis correlações entre a grelina, insulina, resistência insulínica e índice de massa corporal (IMC) como indicadores de obesidade. MÉTODOS: Foram incluídos neste estudo 170 indivíduos, sendo 82 com CRC e 88 controles. Os níveis plasmáticos de grelina, insulina e glicose foram medidos em todos os sujeitos utilizando métodos ELISA e glicose oxidase. Além disso, a resistência à insulina foi avaliada pelo cálculo do índice HOMA-IR. RESULTADOS: Os pacientes com CRC apresentaram redução dos níveis de grelina (P<0,001) e maior índice HOMA-IR (P<0.001) do que os controles. Curiosamente, quando os pacientes com CRC foram estratificados com base no local do tumor, níveis mais baixos de grelina e maior índice de HOMA-IR foram observados nos indivíduos com câncer de cólon ou retal versus controles também. Além disso, houve uma correlação negativa entre idade e IMC independente entre os níveis de grelina e HOMA-IR (r=-0,365, P<0,05) e uma correlação negativa independente da idade entre os níveis de grelina e IMC (r=-0,335, P<0,05) no subgrupo retal. CONCLUSÃO: Nossos achados apoiam o papel da grelina em relação à resistência à insulina e à obesidade na suscetibilidade do CRC; no entanto, ela precisa ser corroborada por estudos posteriores.


Subject(s)
Humans , Insulin Resistance , Colorectal Neoplasms , Body Mass Index , Ghrelin , Obesity/complications
8.
Rev. ecuat. pediatr ; 22(2): 1-7, 31 de agosto del 2021.
Article in Spanish | LILACS | ID: biblio-1284501

ABSTRACT

Introducción: La enfermedad de hígado graso no alcohólica se caracteriza por la infiltración grasa mayor al 5% y que en la población pediátrica se encuentra asociada a alteraciones metabólicas adquiridas o congénitas, con alta prevalencia en población hispánica. El objetivo del presente estudio fue establecer la correlación entre el índice de masa corporal y el grado ecográfico de esteatosis hepática en niños y adolescentes asistentes a una consulta de control de salud. Métodos: El presente estudio observacional, analítico, de corte transversal, retrospectivo, se llevó a cabo en pacientes de 2 a 17 años de edad con esteatosis hepática, atendidos en el área de consulta externa del Hospital de Niños Dr. Roberto Gilbert Elizalde , Guayaquil-Ecuador, entre los años 2015 a 2019. Se midió el peso, talla, índice de masa corporal, grado de esteatosis y niveles de AST y ALT. Se estableció un análisis de correlación entre esteatosis como variable dependiente. Resultados: Ingresaron al estudio 77 casos con una media de 11 años y el género femenino representó el 39% de la muestra. No hubo asociación entre el grado ecográfico de esteatosis hepática vs. la edad, género, peso, talla o índice de masa corporal. En el análisis entre los niveles de transaminasas en pacientes con grado ecográfico leve a severo, se observó un ascenso significativo de AST (P=0.003) y medianamente significativo de ALT (P=0.0583). Conclusiones: Este estudio demostró la ausencia de correlación del grado ecográfico de esteatosis con el índice de masa corporal. La detección temprana con las herramientas adecuadas de la esteatosis hepática debe ser una prioridad en el cuidado de los pacientes pediátricos para evitar su progresión a cirrosis hepática, por lo cual se recomienda el uso de transaminasas como método de cribado a los pacientes con factores de riesgo.


Introduction: Nonalcoholic fatty liver disease is characterized by fat infiltration greater than 5% and that in the pediatric population is associated with acquired or congenital metabolic alterations, with a high prevalence in the Hispanic population. The aim of the present study was to establish the correlation between the body mass index and the ultrasound grade of hepatic steatosis in children and adolescents attending a health check-up. Methods: The present observational, analytical, cross-sectional, retrospective study was carried out in patients from 2 to 17 years of age with hepatic steatosis, treated in the outpa-tient area of the "Dr. Roberto Gilbert Elizalde" Children´s Hospital, Guayaquil -Ecuador, between the years 2015 to 2019. Weight, height, body mass index, degree of steatosis and AST and ALT levels were measured. A correlation analysis was established between steatosis as a dependent variable. Results: 77 cases with an average age of 11 years entered the study and the female gender represented 39% of the sample. There was no association between the ultrasound grade of hepatic steatosis vs. age, gender, weight, height, or body mass index. In the analysis be-tween transaminase levels in patients with mild to severe ultrasound grade, a significant rise in AST (P = 0.003) and a moderately significant rise in ALT (P = 0.0583) were observed. Conclusions: This study demonstrated the absence of correlation of the ultrasound grade of steatosis with the body mass index. Early detection of hepatic steatosis with the appropriate tools should be a priority in the care of pediatric patients to avoid its progression to liver cirrhosis, for which the use of transaminases as a screening method is recommended for patients with risk factors.


Introdução: A doença hepática gordurosa não alcoólica é caracterizada por infiltração gordurosa maior que 5% e que na população pediátrica está associada a alterações metabólicas adquiridas ou congênitas, com alta prevalência na população hispânica. O objetivo do presente estudo foi estabelecer a correlação entre o índice de massa corporal e o grau ultrassonográfico de esteatose hepática em crianças e adolescentes em exame de saúde. Métodos: O presente estudo observacional, analítico, transversal e retrospectivo foi realizado em pacientes de 2 a 17 anos com esteatose hepática, atendidos no ambulatório do Hospital de Niños Dr. Roberto Gilbert Elizalde, Guayaquil-Equador, entre os anos de 2015 a 2019. Peso, altura, índice de massa corporal, grau de esteatose e níveis de AST e ALT foram medidos. Uma análise de correlação foi estabelecida entre a esteatose como variável dependente. Resultados: Entraram no estudo 77 casos com idade média de 11 anos e o gênero feminino representou 39% da amostra. Não houve associação entre o grau de ultrassom de esteatose hepática vs. idade, sexo, peso, altura ou índice de massa corporal. Na análise entre os níveis de transaminase em pacientes com grau de ultrassom de leve a grave, um aumento significativo na AST (P = 0,003) e um aumento moderadamente significativo na ALT (P = 0,0583) foram observados. Conclusões: Este estudo demonstrou não haver correlação do grau de esteatose ultrassonográfica com o índice de massa corporal. A detecção precoce da esteatose hepática com as ferramentas adequadas deve ser uma prioridade no atendimento de pacientes pediátricos para evitar sua progressão para cirrose hepática, para a qual o uso de transaminases como método de rastreamento é recomendado para pacientes com fatores de risco.


Subject(s)
Humans , Child, Preschool , Child , Adolescent , Ultrasonography , Non-alcoholic Fatty Liver Disease , Obesity , Child , Alanine Transaminase
9.
Salud(i)ciencia (Impresa) ; 24(6): 294-303, 06/2021.
Article in Spanish | LILACS | ID: biblio-1343622

ABSTRACT

Kuhn in 1962 establishes the revolutionary character of science: "new scientific theories are not born by verification or falsification, but by substitution." The objective of this review was to analyze the ideas and paradigms through which studies on obesity and its relationship with environmental pollutants, diet and epigenetics have passed, in order to illustrate the current situation of this object of study. Articles were managed in December 2020 from the Web of Science. The strategy was Obesity AND (pollution OR contamination) in the Title field, AND (epigenetic* OR obesity OR food OR nutrition OR diet) in the Themes field. 654 articles were obtained: 577 original investigations and 77 reviews. The documents were exported in BibTeXformat to be quantitatively analyzed with the Bibliometrix program. For the qualitative analysis, review articles were selected in whose titles, keywords and/or abstract, carried the word paradigm*, identifying 19 who underwent content analysis. From 1980 to 2020, four periods were recognized, the first and third are classified as normal science; the second and the fourth, crisis of knowledge or revolution. The evolution of the studies has been differentiated. First, the central theme was environmental pollution and secondarily, obesity. For the second and third period, the epigenetics related to environmental pollution and that associated with obesity are investigated separately and at present, causal relationships between environmental pollutants and obesity, nutrients and epigenetics are hypothesized.


Kuhn en 1962 establece el carácter revolucionario de la ciencia: "las nuevas teorías científicas no nacen por verificación ni por falsación, sino por sustitución". El objetivo de esta revisión fue analizar las ideas y los paradigmas por los que han transitado los estudios sobre obesidad, y su relación con contaminantes ambientales, alimentación y epigenética, con el propósito de ilustrar la situación actual de este objeto de estudio. Se gestionaron artículos en diciembre de 2020 de la Web of Science. La estrategia fue Obesity AND (pollution OR contamination) en el campo Title, AND (epigenetic* OR obesity OR alimentation OR nutrition OR diet) en el campo Themes. Se obtuvieron 654 artículos: 577 investigaciones originales y 77 revisiones. Los documentos se exportaron en formato BibTeX para ser analizados cuantitativamente con el programa Bibliometrix. Para el análisis cualitativo se seleccionaron artículos de revisión en cuyos títulos, palabras clave o resumen llevaran la palabra paradigm*, con lo que se identificaron 19, a los que se les realizó análisis de contenido. De 1980 a 2020 se reconocieron cuatro períodos; el primero y el tercero se clasifican como ciencia normal; el segundo y el cuarto, como crisis de conocimiento o revolución. La evolución de los estudios ha sido diferenciada. Primero, la temática central fue la contaminación ambiental y, de manera secundaria, la obesidad. Para el segundo y el tercer período se investigan por separado la epigenética relacionada con la contaminación ambiental y la asociada con la obesidad, y en la actualidad, se plantean hipótesis de relaciones causales entre contaminantes ambientales y obesidad, nutrientes y epigenética.


Subject(s)
Environmental Pollution , Obesity , World Health Organization , Diet , Environmental Pollutants , Evaluation Studies as Topic , Nutritional Sciences , Epigenomics
10.
Salud(i)ciencia (Impresa) ; 24(6): 289-293, 06/2021. graf., tab.
Article in Spanish | LILACS | ID: biblio-1343450

ABSTRACT

In the population of Manabí, there is a tendency to develop new forms and lifestyles with less energy expenditure and a high degree of stress, and massive consumption of foods rich in saturated fat. An observational, prospective cross-sectional study was carried out with the objective of determining the prevalence of metabolic syndrome in the Las Pampas commune of the Montecristi canton in a sample of 96 people over 30 years of age, whose weight and height were determined calculating the body mass index. Blood pressure, glycaemia, and lipid profile were measured in all of them, after fasting for 12 hours. The data collected from the surveys and the taking of metabolic measurements were tabulated and graphical representations with percentages were made, they were entered into an Access database by a data entry clerk. For the diagnosis of metabolic syndrome, the recommendations of the ALAD 2010 guidelines were taken into account. It is concluded that the risk factors in the population are overweight and obesity, a prevalence of hypertension of 60.42%, and in relation to the syndrome metabolic, female sex predominates with 52%, compared to men with 44%. According to the results obtained, the said results of the project should be indicated to the studied population in order to carry out actions that promote chronic disease prevention campaigns and thus improve the quality of life of the population.


En la población de Manabí existe una tendencia a desarrollar nuevas formas y estilos de vida, con menos gasto de energía y alto grado de estrés, así como un consumo masivo de alimentos ricos en grasas saturadas. Se realizó un estudio observacional, prospectivo, de corte transversal, con el objetivo de determinar la prevalencia de síndrome metabólico en la comuna Las Pampas del cantón Montecristi, en una muestra de 96 personas mayores de 30 años, a las que se les determinaron el peso y la talla, con lo que se calculó el índice de masa corporal. A todos se les midieron la presión arterial, la glucemia y el perfil lipídico, previo ayuno de 12 horas. Los datos recolectados de las encuestas y la toma de medidas metabólicas fueron tabulados y se realizaron representaciones gráficas con porcentajes; se ingresaron a un digitador en una base de datos Access. Para el diagnóstico de síndrome metabólico se tuvieron en cuenta las recomendaciones de las guías ALAD 2010. Se concluye que los factores de riesgo en la población analizada son el sobrepeso y la obesidad, con una prevalencia de hipertensión arterial del 60.42%. En relación con el síndrome metabólico, predomina en el sexo femenino, con un 52%, en comparación con el 44% de los hombres. De acuerdo con los resultados obtenidos, se debe indicar a la población estudiada los resultados del proyecto para poder realizar acciones que promuevan campañas de prevención de enfermedades crónicas y, de esta forma, mejorar la calidad de vida de la población.


Subject(s)
Prevalence , Metabolic Syndrome , Chronic Disease , Risk Factors , Arterial Pressure , Heart Disease Risk Factors , Hypertension , Obesity
11.
Rev. bras. med. esporte ; 27(2): 170-173, Apr.-June 2021. tab
Article in English | LILACS | ID: biblio-1280063

ABSTRACT

ABSTRACT Objective: Visfatin may regulate a variety of physiological functions and it has great potential to significantly enhance our knowledge of the treatment of metabolic syndrome. Metabolic syndrome (MS) refers to metabolic abnormalities, such as abdominal obesity, dyslipidemia, high low-density cholesterol, high blood pressure and diabetes, and physical activity is an important factor for the management of MS. Therefore, the purpose of this study is to investigate the effects of visfatin on MS and MS risk factors through differences in aerobic exercise intensity and exercise type based on the premise of the same amount of exercise (energy expenditure of 400 kcal per day). Method: Thirty two obese, middle-aged women were randomly assigned to exercise intensity groups VO2max 50% (MAE, n=8) and VO2max 80% (VAE, n=8) and to type of exercise groups VO2max 50% + TRX (MARE, n=8) and VO2max 80% + TRX (VARE, n=8). The exercise program was performed 5 times a week. The data was analyzed using two-way repeated measures ANOVA and post-hoc tests within groups with LSD. Results: Body weight (p<.01 and p<.001) and % body fat (p<.05 and p<.01) significantly decreased in all groups and visfatin only increased significantly after exercise in the VARE group (p<.05). TG, glucose, and waist circumstance (p<.05, p<.01, and p<.001) significantly decreased in all groups and HDL-C (p<.05) only increased significantly after exercise only in the MARE group. Conclusion: These results suggest that, in spite of differences in exercise intensity and exercise type, exercise is effective in improving obesity and MS risk factors, but further research is needed on the exact mechanisms of visfatin. Level of evidence I; Therapeutic Studies Investigating the Results of Treatment .


RESUMEN Objetivo: La visfatina puede regular diversas funciones fisiológicas y tiene gran potencial para mejorar significativamente nuestro conocimiento sobre el tratamiento del síndrome metabólico. El síndrome metabólico (SM) se refiere a anormalidades metabólicas, como obesidad abdominal, dislipidemia, colesterol de baja densidad elevado, hipertensión y diabetes, siendo la actividad física un factor importante para el manejo del SM. Siendo así, el objetivo de este estudio es investigar los efectos de la visfatina sobre los factores de riesgo de SM por medio de diferencias de la intensidad de ejercicios aeróbicos y del tipo de ejercicio, con base en la premisa de misma cantidad de ejercicio (gasto energético de 400 kcal por día). Método: Treinta y dos mujeres obesas de media edad fueron aleatoriamente designadas para grupos de intensidad de ejercicio con VO2máx de 50% (EAM, n = 8) y VO2máx de 80% (EAV, n = 8) y grupos con VO2máx de 50% + ERC (EARM, n = 8) y VO2máx de 80% + ERC (EARV, n = 8). El programa de ejercicios fue realizado cinco veces por semana. Los datos fueron analizados con ANOVA de dos vías con medidas repetidas y tests post-hoc en los grupos con DMS. Resultados: El peso corporal (p < 0,01 y p < 0,001) y porcentual de grasa corporal (p < 0,05 y p < 0,01) disminuyeron significativamente en todos los grupos y la visfatina sólo aumentó significativamente después del ejercicio en el grupo EARV (p < 0,05). Los triglicéridos, la glucosa y la circunferencia de la cintura (p < 0,05, p < 0,01 e p < 0,001) disminuyeron significativamente en todos los grupos y el HDL-C (p < 0,05) sólo aumentó significativamente después del ejercicio sólo en el grupo EARM. Conclusión: Esos resultados sugieren que, a pesar de las diferencias de intensidad y tipo de los ejercicios, los mismos son eficaces para mejorar la obesidad y los factores de riesgo del SM, por ende, son necesarias más investigaciones sobre los mecanismos exactos de la visfatina. Nivel de Evidencia I; Estudios terapéuticos - Investigación de los resultados del tratamiento .


RESUMO Objetivo: A visfatina pode regular diversas funções fisiológicas e tem grande potencial para aprimorar significativamente nosso conhecimento sobre o tratamento da síndrome metabólica. A síndrome metabólica (SM) refere-se a anormalidades metabólicas, como obesidade abdominal, dislipidemia, colesterol de baixa densidade elevado, hipertensão e diabetes, sendo a atividade física um fator importante para o manejo da SM. Assim sendo, o objetivo deste estudo é investigar os efeitos da visfatina sobre os fatores de risco de SM por meio de diferenças da intensidade de exercícios aeróbicos e do tipo de exercício, com base na premissa de mesma quantidade de exercício (gasto energético de 400 kcal por dia). Método: Trinta e duas mulheres obesas de meia-idade foram randomicamente designadas para grupos de intensidade de exercício com VO2máxde 50% (EAM, n = 8) e VO2máxde 80% (EAV, n = 8) e grupos com VO2máxde 50% + ERC (EARM, n = 8) e VO2máxde 80% + ERC (EARV, n = 8). O programa de exercícios foi realizado 5 vezes por semana. Os dados foram analisados com ANOVA de duas vias com medidas repetidas e testes post-hoc nos grupos com DMS. Resultados: O peso corporal (p < 0,01 e p < 0,001) e percentual de gordura corporal (p < 0,05 e p < 0,01) diminuíram significativamente em todos os grupos e a visfatina só aumentou significativamente depois do exercício no grupo EARV (p < 0,05). Triglicérides, glicose e circunferência da cintura (p < 0,05, p < 0,01 e p < 0,001) diminuíram significativamente em todos os grupos e o HDL-C (p < 0,05) só aumentou significativamente depois o exercício apenas no grupo EARM. Conclusão: Esses resultados sugerem que, apesar das diferenças de intensidade e tipo dos exercícios, eles são eficazes para melhorar a obesidade e os fatores de risco da SM, porém, são necessárias mais pesquisas sobre os mecanismos exatos da visfatina. Nível de Evidência I; Estudos terapêuticos - Investigação dos resultados do tratamento .


Subject(s)
Humans , Female , Adult , Middle Aged , Exercise , Metabolic Syndrome/enzymology , Nicotinamide Phosphoribosyltransferase/metabolism , Obesity/enzymology , Oxygen Consumption , Anthropometry , Risk Factors , Metabolic Syndrome/blood , Obesity/blood
12.
Con-ciencia (La Paz) ; 9(1): 1-18, jun. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1284378

ABSTRACT

INTRODUCCIÓN: la obesidad es una enfermedad crónica que conlleva a la aparición de enfermedades cardiovasculares y diabetes mellitus tipo 2 (DM2). Pacientes con sobrepeso, obesidad o DM2 presentan generalmente un perfil lipídico con niveles sanguíneos elevados de colesterol, triglicéridos, LDL (lipoproteínas de baja densidad) y VLDL-c (lipoproteínas de muy baja densidad unidas al colesterol) y niveles bajos de HDL-c (lipoproteínas de alta densidad). Pseudocereales como Amaranthus caudatus (Amaranto), Chenopodium quinoa (Quinua) y Lupinus mutabilis (Tarwi) presentes en la región Andina de Bolivia, tienen propiedades potencialmente nutracéuticas, con un alto contenido de macronutrientes y diversos fitoquímicos con actividad biológica como alcaloides de quinolizidina, saponinas, triterpenos y γ-conglutina. OBJETIVO: determinar el efecto del consumo de un producto natural elaborado a base de granos de Amaranto, Quinua y Tarwi (AQT), sobre el perfil lipídico en pacientes con obesidad y DM2. MÉTODO: estudio clínico preliminar controlado, prospectivo, doble ciego y cruzado realizado en el Área de Farmacología del Instituto de Investigaciones Fármaco Bioquímicas de la Facultad de Ciencias Farmacéuticas y Bioquímicas de la Universidad Mayor de San Andrés. RESULTADOS: el consumo de un producto elaborado a base de harinas de Amaranto, Quinua y Tarwi (AQT) durante 3 meses, promovió la disminución significativa de colesterol, triglicéridos, LDL y VLDLc en pacientes diabéticos (DM2) con sobrepeso (IMC>25), sin embargo, los niveles de HDL-c no sufrieron cambios significativos. CONCLUSIÓN: por tanto, el producto AQT tiene efectos beneficiosos sobre el perfil lipídico en pacientes con sobrepeso u obesidad y con riesgo de padecer enfermedades cardiovasculares y DM2.


INTRODUCTION: obesity is a chronic disease that leads to the onset of cardiovascular diseases and type 2 diabetes mellitus (T2DM). Overweight, obese or T2DM patients generally have a lipid profile with high blood levels of cholesterol, triglycerides, LDL (low-density lipoprotein) and VLDL-c (very low-density lipoprotein) and low levels of HDL-c (high-density lipoprotein of cholesterol). Pseudocereals such as Amaranthus caudatus (Amaranth), Chenopodium quinoa (Quinoa) and Lupinus mutabilis (Tarwi) present in the Andean region of Bolivia, have potentially nutraceutical properties, with a high content of macronutrients and various phytochemicals with biological activity such as quinolizidine alkaloids, saponins, triterpenes and γ-conglutin. OBJECTIVE: to determine the effect due to natural product intake made with Amaranth, Quinoa and Tarwi (AQT) on the lipid profile in patients with obesity and T2DM. METHOD: controlled, prospective, double blinded and crossed Preliminary Clinical Assay, performed in the Pharmacology Area of Instituto de Investigaciones Fármaco Bioquímicas from Facultad de Ciencias Farmacéuticas y Bioquímicas, Universidad Mayor de San Andrés. RESULTS: the intake of a product made from Amaranth, Quinoa and Tarwi (AQT) flour for 3 months, promoted a significant decrease in cholesterol, triglycerides, LDL and VLDL-c in overweight diabetic patients (DM2) (BMI> 25) However, HDL-c levels did not undergo significant changes. CONCLUSION: therefore, the AQT product has beneficial effects on the lipid profile in patients who are overweight or obese and at risk of cardiovascular disease and T2DM.


Subject(s)
Diabetes Mellitus, Type 2 , Triticum , Amaranthus , Chenopodium quinoa , Lipids , Obesity
13.
Rev. cuba. pediatr ; 93(2): e1417, tab, fig
Article in Spanish | LILACS, CUMED | ID: biblio-1280364

ABSTRACT

Introducción: La asociación de asma y obesidad ha aumentado su prevalencia en los últimos años. Objetivos: Caracterizar a niños y adolescentes asmáticos con obesidad asociada. Métodos: Investigación descriptiva, transversal y prospectiva, 2017-2018, Servicio de Neumología, Hospital Pediátrico Universitario Centro Habana. Se evaluaron 43 pacientes asmáticos entre 5 y 18 años de edad con obesidad exógena asociada. Se exploraron edad, sexo, antecedentes familiares de asma y obesidad, severidad y grado de control del asma. Se realizaron estudios para evaluar el metabolismo lipídico y de los hidratos de carbono. Resultados: La distribución por edades fue similar (escolares, adolescencia temprana y tardía), predominó el sexo masculino en escolares: 11 de 16 (68,7 por ciento) y el femenino en la adolescencia tardía: 12 de 15 (80 por ciento). Se refirieron antecedentes familiares de obesidad en 5 (11,6 por ciento) y asma asociada a obesidad en 26 (60,5 por ciento); la mayoría presentaba asma persistente leve: 38 (88,4 por ciento), no controlados: 28 (65,1 por ciento) y parcialmente controlados 10 (23,3 por ciento). Dos pacientes presentaban intolerancia a los hidratos de carbono (4,7 por ciento), uno de ellos con resistencia a la insulina. La dislipidemia fue el trastorno metabólico más frecuente: colesterol sérico elevado en 23 (53,5 por ciento), LDLc alto en 13 (30,2 por ciento) y HDLc bajo en 10 (23,3 por ciento). Conclusiones: Los niños asmáticos con historia familiar de obesidad tienen alto riesgo de ser también obesos, lo cual puede dificultar el control del asma; son frecuentes en ellos las alteraciones metabólicas(AU)


Introduction: The association of asthma and obesity has increased its prevalence in recent years. Objectives: Characterize asthmatic children and adolescents with associated obesity. Methods: Descriptive, cross-sectional and prospective research, 2017 - 2018, Pneumology Service, Centro Habana University Pediatric Hospital. 43 asthmatic patients from 5 to 18 years old with associated exogenous obesity were assessed. Age, sex, family history of asthma and obesity, severity and degree of asthma control were studied. Studies were conducted to evaluate lipid and carbohydrate metabolism. Results: Age distribution was similar (schoolers, early and late adolescence), predominated male sex in schoolchildren (11 of 16 - 68.7 percent) and the female in late adolescence (12 of 15 -80 percent). Family history of obesity was reported in 5 patients (11.6 percent) and obesity-associated asthma in 26 (60.5 percent); most had mild persistent asthma (38 -88.4 percent) poorly controlled: 28 uncontrolled (65.1 percent) and 10 partially controlled (23.3 percent). Two patients had carbohydrate intolerance (4.7 percent), one of them with insulin resistance. Dyslipidemia was the most common metabolic disorder: serum cholesterol increased in 23 - 53.5 percent, high LDLc in 13 - 30.2 percent, and low HDLc in 10 - 23.3 percent. Conclusions: Asthmatic children with a family history of obesity are also at high risk of being obese, which can make difficult to control asthma; metabolic alterations are common in them(Au)


Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Asthma , Age Distribution , Dyslipidemias , Carbohydrate Metabolism , Obesity
14.
Aquichan ; 21(2): e2128, jun. 25, 2021.
Article in English | LILACS, BDENF, COLNAL | ID: biblio-1283802

ABSTRACT

Objetivos: associar a percepção materna do peso do filho (PMPF) e o estado nutricional dele. Descrever problemas comportamentais do estilo de vida do filho (PCEV) e autoeficácia materna (AE) para lidar com eles, verificar diferenças entre com e sem excesso de peso-obesidade (EP-OB) do filho e PMPF. Materiais e métodos: participaram 274 díades (mãe-filho em idade pré-escolar). A PMPF foi avaliada por meio de palavras e imagens. As mães responderam à Lista de Verificação de Comportamentos do Estilo de Vida. Peso e altura do filho foram medidos. Resultados: 18,8 % (n = 13) mães de filos com EP-OB e 78,8 % (n = 160) mães de filhos sem EP-OB tiveram PMPF adequada por palavras (X 2 = 77.759; gl = 1; p < ,001). Foi identificado que as mães de filhos com EP-OB referiram mais PCEV e menos AE. As mães de filhos com EP-OB tiveram que lidar com mais baixa AE e mais PCEV. Quando as mães percebem o EP-OB do filho por palavras, têm menos AE (U = 1118, p = ,015) e mais PCEV (F = 17,041, p = ,001). Conclusões: PMPF não adequada predominou em mães de filhos com EP-OB. Quando o EP-OB é percebido, mais PCEV e menos AE. Promover PMPF adequada particularmente em mães de filhos com EP-OB é recomendado. As imagens ajudam a reconhecer o EP-OB do filho mais do que a classificá-lo numa categoria.


Objetivos: asociar la percepción materna del peso del hijo (PMPH) y estado nutricional del hijo. Describir problemas conductuales del estilo de vida del hijo (PCEV) y autoeficacia materna (AE) para manejarlos, verificar diferencias conforme a con y sin sobrepeso-obesidad (SP-OB) del hijo y PMPH. Material y métodos: participaron 274 diadas (madre-hijo preescolar). La PMPH se evalúo por palabras e imágenes. Las madres contestaron la Lista de Verificación de Conductas del Estilo de Vida. Se midió peso y talla del hijo. Resultados: 18.8 % (n = 13) madres de hijos con SP-OB y 78.8 % (n = 160) madres de hijos sin SP-OB tuvieron PMPH adecuada por palabras (X2 = 77.759, gl = 1, p < .001). Las madres de hijos con SP-OB tuvieron que manejar más baja AE y más PCEV. Cuando las madres perciben el SP-OB del hijo por palabras, tienen menor AE (U = 1118, p = .015) y más PCEV (F = 17.041, p = .001). Conclusiones: Predominó PMPH no adecuada en madres de hijos con SP-OB. Cuando se percibe el SP-OB, más PCEV y menor AE. Se recomienda promover PMPH adecuada particularmente en madres de hijos con SP-OB. Las imágenes ayudan a reconocer el SP-OB del hijo más que a clasificarlo en una categoría.


Objectives: To associate the maternal perception of the child's weight (MPCW) and the child's nutritional status. To describe child's lifestyle behavior problems (CLBPs) and maternal self-efficacy (SE) to deal with them, as well as to verify differences according to children with and without overweight-obesity (OW-OB) and MPCW. Material and methods: There was participation of 274 dyads (mother-preschool child). MPCW was assessed through words and images. The mothers answered the Lifestyle Behaviour Checklist. The child's weight and height were measured. Results: 18.8 % (n = 13) of the mothers of children with OW-OB and 78.8 % (n = 160) of the mothers of children without OW-OB obtained adequate MPCW values through words (X2 = 77.759; DoF = 1; p < .001). It was identified that the mothers of children with OW-OB reported more CLBPs and less SE. When the child's OW-OB is perceived through words, there are more CLBPs (F = 17.041; p = .001) and less SE (U = 1,118; p = .015). Conclusions: Inadequate MPCW was predominant in mothers of children with OW-OB. When OW-OB is perceived, there are more CLBPs and fewer SE. It is recommended to promote adequate MPCW, particularly in mothers of children with OW-OB. Images assist in the identification of the child's OW-OB more than to classify it into a category.


Subject(s)
Weight Perception , Child, Preschool , Self Efficacy , Problem Behavior , Obesity
15.
Gac. méd. boliv ; 44(1): 40-43, jun. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1286597

ABSTRACT

Objetivo: determinar la prevalencia y la asociación de enfermedades musculoesqueléticas con el sobrepeso y obesidad, y las diferencias respecto a edad y sexo. Métodos: el presente estudio es de tipo transversal, descriptivo y analítico, el universo está compuesto por pacientes adultos mayores a 60 años con diagnóstico de enfermedades musculoesqueléticas que acuden a consulta en el periodo de enero a diciembre, del año 2019, en el centro de salud "Villa Oruro", en Tiquipaya, Cochabamba, Bolivia, con un muestreo no probabilístico por conveniencia, la muestra del estudio fue 353 pacientes. Resultados: se evaluó a 353 pacientes mayores a 60 años, 156 hombres y 197 mujeres, con una edad promedio de 71,51 ± 8,45 con índice de masa corporal promedio de 26,68 ± 1,77. Se realizó el análisis estadístico de asociación de variables categóricas, en base a rangos del índice de masa corporal (sobrepeso y obesidad) con las enfermedades musculoesqueléticas. Conclusiones: dentro de la evaluación del sobrepeso y obesidad, y su relación con patologías musculoesqueléticas, la gonartrosis es la más relacionada con la presencia de sobrepeso y obesidad, por lo que se recomienda establecer métodos de educación en la población con hábitos alimenticios y estilos de vida saludables para disminuir la prevalencia de enfermedades musculoesqueléticas asociadas a sobrepeso y obesidad.


Objectives: the aim of this study is to determine the prevalence and association of musculoskeletal diseases with overweight and obesity, and the differences with respect to age and sex. Methods: this type of study is cross-sectional, descriptive and analytical, the universe is composed of adult patients over 60 years of age with a diagnosis of musculoskeletal diseases who come for consultation in the period from January to December, year 2019, of the health center "Villa Oruro", Tiquipaya, Cochabamba, Bolivia, with a non-probabilistic sampling by convenience, the study sample was 353 patients. Results: we evaluated 353 patients over 60 years of age, 156 men and 197 women, with an average age of 71.51 ± 8.45 with an average body mass index of 26.68 ±1.77. Statistical analysis of association of categorical variables, based on body mass index ranges (overweight and obesity) with musculoskeletal diseases, was performed. Conclusions: within the evaluation of overweight and obesity, and their relationship with musculoskeletal pathologies, gonarthrosis is the most related to the presence of overweight and obesity, it is recommended and establish education in the population with healthy eating habits and lifestyles to reduce the prevalence of musculoskeletal diseases associated with overweight and obesity.


Subject(s)
Obesity
16.
Arch. latinoam. nutr ; 71(2): 149-160, jun. 2021. tab
Article in Spanish | LILACS, LIVECS | ID: biblio-1290920

ABSTRACT

Las Guías Alimentarias Basadas en Alimentos (GABA) son un instrumento nacional de educación nutricional destinadas a la población general. En el contexto de alta prevalencia de enfermedades crónicas no transmisibles, relacionadas con dietas inadecuadas, buscan contribuir a alcanzar mejores estándares de alimentación. En el contexto americano, de alta prevalencia de sobrepeso y obesidad, las GABA forman parte de un conjunto de políticas gubernamentales para combatir estos problemas. El objetivo de este ensayo fue realizar un análisis comparativo de las GABA en nueve países americanos: Canadá, Chile, Estados Unidos, México, Paraguay, Colombia, Brasil, Uruguay y Argentina. Para la comparación se seleccionaron siete dimensiones generales: política, metodología, participación, mensajes, aspectos socioculturales, aspectos ambientales, y de implementación y evaluación, a partir de las recomendaciones para la elaboración de las GABA de organismos internacionales (FAO-OMS). Los resultados revelaron brechas en las guías de los países estudiados, destacando Brasil como uno de los países que pone mayor atención a la participación y a la incorporación de factores socioculturales en la producción de su documento. Mientras que Chile elude elementos como el género, el acceso y disponibilidad, la diversidad cultural, la sostenibilidad y los entornos alimentarios. Con guías alimentarias que abordan escasamente la propuesta FAO-OMS, es de esperar que en una futura actualización se consideren las dimensiones propuestas en un formato de desarrollo basado en la participación ciudadana, intersectorial y de expertos/as, fortaleciendo los aspectos socioculturales y ambientales(AU)


The Food-Based Dietary Guidelines (GABA) are a national instrument of nutritional education aimed at the general population. In the context of the high prevalence of chronic non-communicable diseases, related to inadequate diets, they seek to contribute to achieving better food standards. In the American context, with a high prevalence of overweight and obesity, GABAs are part of a set of government policies to fight against these problems. The objective of this trial was to perform a comparative analysis of GABA in nine American countries: Canada, Chile, the United States, Mexico, Paraguay, Colombia, Brazil, Uruguay, and Argentina. Seven general dimensions were selected for comparison: policy, methodology, participation, messages, sociocultural aspects, environmental aspects and, implementation and evaluation-, based on the recommendations for the elaboration of the GABA of international organizations (FAO-WHO). The results revealed gaps in the guidelines of the countries studied, highlighting Brazil as one of those that pay the most attention to participation and the incorporation of sociocultural factors in the production of its document. While Chile avoids elements such as gender, access and availability, cultural diversity, sustainability and food environments. With dietary guidelines that barely address the FAO-WHO proposal, it is expected that in a future update, the proposed dimensions will be considered in a development format based on citizen, intersectoral and expert participation, strengthening socio-cultural and environmental aspects(AU)


Subject(s)
Humans , Male , Female , Chronic Disease , Nutrition Policy , Food Guide , Nutritive Value , Overweight , Diet, Food, and Nutrition , Obesity
17.
Arch. latinoam. nutr ; 71(2): 138-148, jun. 2021. tab, graf
Article in English | LILACS, LIVECS | ID: biblio-1290912

ABSTRACT

Reflex-ontogeny and intestinal morphometrics were evaluated in Wistar rats whose mothers were fed on a high-fat diet during the perinatal period. Male pups (n=52) formed four experimental groups: NN (pups from mothers with lab chow diet during gestation and lactation); NH (pups from mothers with lab chow diet during pregnancy and high-fat in lactation); HH (pups from mothers with high-fat diet during gestation and lactation); HN (pups from mothers with high-fat diet during pregnancy and lab chow in lactation). The reflex ontogeny, the maturation of physical characteristics and parameters of somatic growth were evaluated during lactation. In addition, the body mass index (BMI), the specific rate of weight gain (SRWG), the Lee index, the weight of the brain and intestinal parameters were analyzed after weaning. High-fat diet during pregnancy (HH and HN groups) delayed the maturation of reflexes and physical characteristics. The high-fat diet affected somatic growth differently, reducing somatic growth parameters in the groups NH and HH and increasing in the HN group. The highest SRWG was found in group HN. SRWG and BMI were reduced in the groups NH and HH. The relative intestinal weight was reduced in the groups NH, HH and HN. The relative length of small intestine was longer in group HN than in group NN. The total height of the mucosa and size of the villous were lower in group HH than in group NN. In conclusion, high-fat diet promoted negative consequences for the development of the nervous and enteric systems of the offspring(AU)


Ontogenia refleja y morfometría intestinal fueron evaluados en crías de ratas Wistar que fueron alimentadas con una dieta alta en grasas durante el período perinatal. Los descendientes machos (n = 52) formaron cuatro grupos experimentales: NN (hijos de madres que utilizaron alimentos de laboratorio durante la gestación y la lactancia); NH (hijos de madres que comieron dieta de laboratorio durante el embarazo y dieta con un alto contenido de grasas en la lactancia); HH (hijos de madres con una dieta alta en grasas durante el embarazo y la lactancia); HN (hijos de madres que comieron una dieta alta en grasas durante el embarazo y comida de laboratorio durante la lactancia). La ontogenia refleja, la maduración de las características físicas y los parámetros de crecimiento somático durante la lactancia fueron evaluados. Además, el índice de masa corporal (IMC), la tasa específica de aumento de peso (SRWG), el índice de Lee, el peso cerebral y los parámetros intestinales fueron analizados después del destete. La dieta alta en grasas durante el embarazo (grupos HH y HN) retrasó la maduración de reflejos y características físicas. La dieta alta en grasas afectó el crecimiento somático de manera diferente, reduciendo los parámetros de crecimiento somático en los grupos NH y HH y aumentando en el grupo HN. El SRWG más grande se encontró en el grupo HN. El SRWG y el IMC se redujeron en los grupos NH y HH. El peso relativo intestinal se redujo en los grupos NH, HH y HN. La longitud relativa del intestino delgado fue mayor en el grupo HN que en el grupo NN. La altura total de la mucosa y el tamaño de las vellosidades fueron menores en el grupo HH que en el grupo NN. En conclusión, la dieta alta en grasas tuvo consecuencias negativas para el desarrollo de los sistemas nervioso y entérico de la prole(AU)


Subject(s)
Rats , Breast Feeding , Dietary Fats , Gene Ontology , Dietary Sugars , Chronic Disease , Obesity
18.
RECIIS (Online) ; 15(2): 540-547, abr.-jun. 2021. ilus
Article in Portuguese | LILACS | ID: biblio-1280895

ABSTRACT

O livro de Igor Sacramento e Wilson Couto Borges oferece um excelente material para o estudo das representações midiáticas da saúde. Além de apresentarem um panorama teórico da representação, enquanto parte do processo de construção da realidade e dos grupos sociais, os autores adotam metodologicamente como categoria analítica a noção de posição dos sujeitos, central para a representação por situar os indivíduos em papeis, e analisam relatos sobre excesso de gordura em matérias jornalísticas, programas televisivos e produções audiovisuais na internet. É possível perceber como a mídia trata o corpo como índice da saúde ou doença e normalidade ou anormalidade pelas formas corporais, exigindo autocontrole das pessoas obesas ou daquelas em risco de se tornarem, o que se justifica por transformações físicas e questões psicossociais.


The book by Igor Sacramento and Wilson Couto Borges offers excellent material for studying health media representations. In addition to presenting a theoretical panorama of representation, as part of the process of constructing reality and social groups, the authors methodologically adopt the notion of subject position as central to the representation, as it places individuals in roles, and analyze reports about excess fat in newspapers, television programs and audio-visual productions on the internet. It is possible to perceive how the media treats the body as an index of health or disease and normality or abnormality due to body shapes, requiring obese people or those at risk to self-control, which is justified by physical changes and psychosocial issues.


El libro de Igor Sacramento y Wilson Couto Borges ofrece excelente material para el estudio de las representaciones mediáticas de la salud. Además de presentar un panorama teórico de la representación, como parte del proceso de construcción de la realidad y de los grupos sociales, los autores adoptan metodológicamente la noción de posición del sujeto, central de la representación, ya que ubican a los individuos en roles, y analizan reportes sobre el exceso de grasa en reportajes, programas de televisión y producciones audiovisuales en Internet. Es posible percibir cómo los medios tratan al cuerpo como un índice de salud o enfermedad y de normalidad o anormalidad por formas corporales, interpelando personas obesas o en riesgo de convertirse para el autocontrol, justificado por cambios físicos y problemas psicosociales.


Subject(s)
Humans , Health , News , Life Style , Mass Media , Obesity , Internet , Overweight , Social Media
19.
Rev. cuba. salud pública ; 47(2): e1096, 2021. graf
Article in Spanish | LILACS, CUMED | ID: biblio-1341493

ABSTRACT

Introducción: El sobrepeso y la obesidad en la infancia y la adolescencia se han incrementado a nivel mundial durante las últimas décadas. Este hecho se asocia, principalmente, con la falta de actividad física, hábitos de vida y comportamientos alimenticios poco saludables. Objetivo: Analizar la efectividad de diferentes estudios de intervención escolar llevados a cabo en España para prevenir y tratar la obesidad en niños y niñas. Métodos: Se realizó una estrategia de búsqueda electrónica utilizando las bases de datos PubMed, Medline y SPORTdiscus y los términos school-based intervention, Spain, healthy lifestyle, obesity prevention, physical activity y nutrition childhood obesity y children obesity. Se identificaron 124 artículos y solo 11 cumplieron los criterios de inclusión. Conclusiones: Las intervenciones realizadas por el entorno escolar no fueron eficaces o significativas para cambiar los indicadores antropométricos de los niños, niñas y adolescentes españoles. Sin embargo, las intervenciones escolares unidas a la implicación familiar, pueden ser eficaces para modificar cambios en los hábitos nutricionales, nivel de actividad física y hábitos de vida saludable en la etapa infantojuvenil, ya que son los principales determinantes de obesidad en la infancia. Por último, la consolidación de un adecuado estilo de vida en etapas tempranas puede prevenir la obesidad y sobrepeso en la adultez(AU)


Introduction: Overweight and obesity in childhood and adolescence have increased worldwide in recent decades. This fact is associated mainly with a lack of physical activity, unhealthy lifestyle habits and eating behaviors. Objective: To analyze the effectiveness of different school intervention studies carried out in Spain to prevent and treat obesity in boys and girls. Methods: An electronic search strategy was carried out using the PubMed, Medline and SPORTdiscus databases, under the terms school-based intervention, Spain, healthy lifestyle, obesity prevention, physical activity, nutrition, childhood obesity and children obesity. 124 articles were identified and only 11 met the inclusion criteria. Conclusions: The interventions carried out by school were not effective or significant to change the anthropometric indicators of Spanish children and adolescents. However, school interventions, together with family involvement, can be effective in modifying changes in nutritional habits, level of physical activity and healthy lifestyle habits in the infant-juvenile stage, since they are the main determinants of obesity in childhood. Finally, establishing an adequate lifestyle early can prevent obesity and overweight in adulthood(AU)


Subject(s)
Humans , Child , Adolescent , Food and Nutrition Education , Exercise , Life Style , Obesity/prevention & control
20.
Arq. gastroenterol ; 58(2): 139-144, Apr.-June 2021. tab, graf
Article in English | LILACS | ID: biblio-1285330

ABSTRACT

ABSTRACT BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in the world, and its prevalence is increasing alongside obesity. In United States, NAFLD is already the second leading cause of liver transplantation. The spectrum of the disease ranges from simple steatosis, which has a benign course, to steatohepatitis, which may progress to cirrhosis and its complications. The rising of noninvasive methods for diagnosing and staging non-alcoholic steatohepatitis (NASH) and fibrosis decreases the need of liver biopsy, as well as the costs and the occurrence of complications related to it. OBJECTIVE: To analyze the performance of the triglyceride-glucose index to evaluate steatosis, NASH and liver fibrosis in obese patients with NAFLD. METHODS: This is a retrospective cross-sectional study. Every medical record of patients who were candidates for bariatric surgery at a leading hospital in Southern Brazil were analyzed. The triglyceride-glucose index (TyG Index), a method composed only of two simple laboratory tests (serum triglycerides and fasting glucose levels), was performed prior to surgery. The TyG Index performance regarding the anatomopathological findings was evaluated, and the AUROC curve was calculated to evaluate the best cut-off point for diagnosing steatosis, non-alcoholic steatohepatitis and liver fibrosis grade. Also, the NAFLD fibrosis Score (NFS) was evaluated. RESULTS: A total of 423 patients were evaluated. The TyG Index with a cut-off point of 8.76 excluded significant simple steatosis (grade 2-3) in obese patients, with 67.6% sensitivity, 65.1% specificity, 46.3% positive predictive value (PPV), 81.8% negative predictive value (NPV), 65.8% accuracy and 0.66 AUROC (P=0.005). In the evaluation of NASH, the TyG Index with a cut-off point of 8.82 excluded significant NASH (grade 2-3) with 57.3% sensitivity, 58.6% specificity, 33.7% PPV, 78.8% NPV, 58.2% accuracy and 0.58 AUROC (P=0.022). When evaluating liver fibrosis, the TyG Index with a cut-off point of 8.91 showed a sensitivity of 61.8%, a specificity of 62.5%, a PPV of 13.8 and a NPV of 94.4% for exclusion of advanced fibrosis (F3-4), with a 62.4% accuracy and 0.69 AUROC (P<0.001). When analyzing the performance of NFS in the diagnosis of advanced fibrosis, the cut-off point <-1.455 excluded advanced fibrosis with sensitivity of 59.4%, specificity of 51%, PPV of 11%, NPV of 92.4% and accuracy of 51.7%. However, the cut-off point of 0.676 to diagnose advanced fibrosis presented sensitivity of 21.9%, specificity of 83%, PPV of 11.7%, NPV of 91.2% and 77.3% accuracy. The AUROC was 0.54 (P=0.480). CONCLUSION: TyG Index did not perform well in the diagnosis of significant steatosis and NASH. However, it was able to exclude advanced fibrosis in obese patients who are candidates for bariatric surgery.


RESUMO CONTEXTO: A doença hepática gordurosa não-alcoólica (DHGNA) é a doença hepática mais prevalente no mundo. Nos Estados Unidos, a DHGNA já é a segunda causa de transplante hepático. O espectro da doença abrange desde a esteatose simples, que apresenta curso benigno, até esteato-hepatite não-alcoólica (EHNA), que pode progredir para cirrose e suas complicações. O desenvolvimento de métodos não invasivos para o diagnóstico e estadiamento da EHNA e da fibrose hepática visa diminuir a necessidade de biópsia hepática, um procedimento invasivo e não raro associado a complicações. OBJETIVO: Analisar o desempenho do índice triglicerídeo-glicose (TyG Index) para o diagnóstico e estadiamento da DHGNA em pacientes obesos. MÉTODOS: Este é um estudo transversal retrospectivo. Foram analisados todos os prontuários de pacientes candidatos a cirurgia bariátrica em um hospital de referência do Sul do Brasil e calculado o TyG Index, um escore composto por dois exames laboratoriais (triglicerídeos e glicose de jejum), realizados previamente à cirurgia. O desempenho do TyG Index em relação aos achados anatomopatológicos hepáticos foi avaliado, e calculada a curva ROC para avaliação de esteatose simples, EHNA e fibrose hepática. O NAFLD Fibrosis Score (NFS) também foi avaliado. RESULTADOS: Foram avaliados 423 pacientes. O melhor ponto de corte do TyG Index para a exclusão de esteatose simples significativa (grau 2-3) foi de 8,76, com sensibilidade 67,6%, especificidade 65,1%, valor preditivo positivo (VPP) 46,3%, valor preditivo negativo (VPN) 81,8%, acurácia 65,8% e AUROC 0,66 (P=0,005). Na avaliação de EHNA significativa (grau 2-3), o melhor ponto de corte foi de 8,82 com sensibilidade 57,3%, especificidade 58,6%, VPP 33,7%, VPN 78,8%, acurácia 58,8% e AUROC 0,58 (P=0,022). Em relação à fibrose avançada (grau 3-4), o melhor ponto de corte do TyG Index foi de 8,91 com sensibilidade 61,8%, especificidade 62,5%, VPP 13,8%, VPN 94,4%, acurácia 62,4% e AUROC 0,69 (P<0,001). Ao analisarmos o desempenho do NFS no diagnóstico de fibrose avançada, o ponto de corte de <-1,455 excluiu fibrose avançada com sensibilidade 59,4%, especificidade 51%, VPP 11%, VPN 92,4% e acurácia 51,7%. Entretanto, o ponto de corte de 0,676 para fibrose avançada apresentou sensibilidade de 21,9%, especificidade 83%, VPP 11,7%, VPN 91,2% e acurácia 77,3%. A AUROC foi de 0,54 (P=0,480). CONCLUSÃO: O TyG Index não apresentou bom desempenho para o diagnóstico e estadiamento da esteatose simples e da EHNA. Entretanto, foi capaz de excluir fibrose avançada em pacientes obesos candidatos a cirurgia bariátrica.


Subject(s)
Humans , Non-alcoholic Fatty Liver Disease/complications , Non-alcoholic Fatty Liver Disease/pathology , Triglycerides , Biopsy , Cross-Sectional Studies , Retrospective Studies , Glucose , Liver/pathology , Liver Cirrhosis/pathology , Obesity
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