Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 20 de 47
Chinese Journal of Pathology ; (12): 364-369, 2023.
Article in Chinese | WPRIM | ID: wpr-985681


Objective: To investigate the clinicopathological features, immunophenotypes and molecular genetics of fibroma of tendon sheath (FTS). Methods: One hundred and thirty-four cases of FTS or tenosynovial fibroma diagnosed in the Department of Pathology, West China Hospital, Sichuan University, Chengdu, China from January 2008 to April 2019 were selected. The clinical and histologic features of these cases were retrospectively reviewed. Immunohistochemistry, fluorescence in situ hybridization (FISH) and reverse transcription-polymerase chain reaction (RT-PCR) were performed on the above cases. Results: There were a total of 134 cases of FTS, including 67 males and 67 females. The patients' median age was 38 years (ranged from 2 to 85 years). The median tumor size was 1.8 cm (ranged from 0.1 to 6.8 cm). The most common site was the upper extremity (76/134, 57%). Follow-up data was available in 28 cases and there was no detectable recurrence. Classic FTS (114 cases) were well-defined and hypocellular. A few spindle-shaped fibroblasts were scattered in the dense collagenous sclerotic stroma. Characteristically elongated slit-like spaces or thin-walled vessels were observed. Most of cellular FTSs (20 cases) were well-defined and the area with increased cellularity of the spindle cells coexisted with classic FTS. There were occasional mitotic figures, but no atypical mitotic figures. Immunohistochemistry was performed in 8 cases of classic FTS and most cases were positive for SMA (5/8). Immunohistochemistry was also performed in 13 cases of cellular FTS and showed 100% positive rate for SMA. FISH was conducted on 20 cases of cellular FTS and 32 cases of classical FTS. USP6 gene rearrangement was found in 11/20 of cellular FTS. Among 12 cases of CFTS with nodular fasciitis (NF)-like morphological feature, 7 cases showed USP6 gene rearrangement. The rearrangement proportion of USP6 gene in cellular FTS without NF-like morphological features was 4/8. By contrast, 3% (1/32) of the classic FTS showed USP6 gene rearrangement. RT-PCR was performed in those cases with detected USP6 gene rearrangement and sufficient tissue samples for RT-PCR. The MYH9-USP6 fusion gene was detected in 1 case (1/8) of the cellular FTSs, while no target fusion partner was detected in the classic FTS. Conclusions: FTS is a relatively rare benign fibroblastic or myofibroblastic tumor. Our study and recent literature find that some of the classic FTS also show USP6 gene rearrangements, suggesting that classical FTS and cellular FTS are likely to be at different stages of the same disease (spectrum). FISH for USP6 gene rearrangement may be used as an important auxiliary diagnostic tool in distinguishing FTS from other tumors.

Male , Female , Humans , Gene Rearrangement , In Situ Hybridization, Fluorescence , Retrospective Studies , Fibroma/pathology , Fasciitis/genetics , Ubiquitin Thiolesterase , Tendons/pathology
Artrosc. (B. Aires) ; 22(4): 142-145, nov.2015.
Article in Spanish | LILACS, BINACIS | ID: lil-776182


Las calcificaciones del manguito rotador afectan mayormente al tendón del supraespinoso. El compromiso del tendón del subescapular es menos frecuente y sólo unos pocos casos han sido reportados. Presentamos un caso de una calcificación del subescapular en un paciente sin respuesta al tratamiento conservador, que fue tratado con la remoción completa de la misma y la posterior reparación del defecto residual con un arpón de doble sutura reforzada. Un año luego de la cirugía el paciente se presentaba sin dolor, con movilidad completa y sin restos de calcio en los estudios postoperatorios. La combinación de la remoción completa de la calcificación y la subsecuente reparación del defecto con arpones en forma artroscópica puede resultar en excelentes resultados funcionales, sin comprometer la integridad del manguito rotador en pacientes con calcificaciones del subescapular. Nivel de Evidencia: V...

The supraspinatus tendon is the most common tendon associated with the calcific tendinosis of the rotator cuff. The subscapularis tendon is rarely affected, and only a few prior cases have been reported. We present a case of a subscapularis tendon calcification in a patient with a failed conservative treatment that was treated arthroscopically with complete removal of the calcific deposit and posterior repair of the defect with suture anchors. One year after surgery the patient had no pain, he had full range of motion and there were not residual calcium deposits in the postoperative studies. The combination of complete calcium removal and posterior repair with suture anchors can led to excellent functional outcomes without compromising the integrity of the rotator cuff in patients with calcifications of the subscapularis tendon. Level Of Evidence: V...

Adult , Shoulder Joint/surgery , Shoulder Joint/pathology , Arthroscopy/methods , Calcinosis/surgery , Scapula/surgery , Tendinopathy/surgery , Tendinopathy/pathology , Tendons/surgery , Tendons/pathology , Treatment Outcome
Artrosc. (B. Aires) ; 22(4): 146-148, nov.2015.
Article in Spanish | LILACS, BINACIS | ID: lil-776183


Se presenta un caso de gonalgia aguda atraumática de causa tumoral localizada paquete adiposo de Hoffa en un paciente pediátrico. Se realizó resección en bloque con asistencia artroscópica. El diagnóstico de tumor de células gigante de vaina tendinosa fue confirmado mediante histopatología. Nivel de evidencia: V...

We report a case of acute atraumatic knee pain due to a soft tissue tumor in Hoffa’s fat pad in a pediatric patient. An arthroscopically assisted en bloc resection was performed. The diagnosis of giant cell tumor of tendon sheath was confirmed through histopathology study. Level of Evidence: V...

Child , Knee Joint/surgery , Arthroscopy/methods , Tendons/surgery , Tendons/pathology , Giant Cell Tumors/surgery , Giant Cell Tumors/pathology , Treatment Outcome
Article in English | WPRIM | ID: wpr-212756


Iliotibial band (ITB) friction syndrome is a common overuse injury typically seen in the active athlete population. A nodular lesion on the inner side of the ITB as an etiology or an accompanying lesion from friction syndrome has been rarely reported. A 45-year-old male presented with recurrent pain and a movable nodule at the lateral joint area, diagnosed as ITB friction syndrome. The nodule was confirmed as a rare intra-articular fibroma of the tendon sheath (FTS) on the basis of histopathologic findings. We describe the MRI findings, arthroscopic and pathologic features, in this case of intra-articular FTS presenting with ITB friction syndrome.

Humans , Male , Middle Aged , Cumulative Trauma Disorders/complications , Fibroma/etiology , Friction , Iliotibial Band Syndrome/complications , Knee Joint/pathology , Magnetic Resonance Imaging , Pain/etiology , Tendons/pathology
Article in English | WPRIM | ID: wpr-100960


The localized type of tenosynovial giant cell tumor usually occurs on the palmar side of fingers and toes. Tenosynovial giant cell tumors of the tendon sheath are rarely intra-articular. We report a giant cell tumor of the tendon sheath arising from femoral attachment of the anterior cruciate ligament and its treatment with arthroscopy in a 28-year-old man.

Adult , Humans , Male , Anterior Cruciate Ligament/pathology , Arthroscopy , Femur , Giant Cell Tumors/diagnosis , Knee , Synovitis, Pigmented Villonodular/diagnosis , Tendons/pathology
Article in English | WPRIM | ID: wpr-228630


OBJECTIVE: To evaluate magnetic resonance imaging (MRI) observer variability to detect ectopic insertion of the pectoralis minor tendon (EIPMT) and to investigate changes in the rotator interval in patients with EIPMT using MRI. MATERIALS AND METHODS: A total of 507 shoulder MRIs (male:female = 259:248; mean age, 55.4 years) were classified into 1) normal type insertion of the pectoralis minor tendon, 2) complete type EIPMT, and 3) partial type EIPMT independently by two radiologists. Inter-observer agreement was calculated using the kappa coefficient. Thickness of the fibrotic scar tissue in the subcoracoid triangle and humeral side axillary recess was measured. MRIs were reviewed by consensus with regard to the grade of fibrotic scar tissue proliferation in the rotator interval. Comparisons were made between normal and EIPMT and between partial and complete type EIPMT. RESULTS: The incidence of EIPMT was 13.4% (complete type, 7.7%; partial type, 5.7%). Inter-observer agreement was substantial (kappa = 0.775). Fibrotic scar tissue in the subcoracoid triangle was thicker, and the grade of fibrotic scar tissue proliferation in the rotator interval was higher in the EIPMT group than those in the control group. No significant difference was observed in the thickness of humeral side axillary recess. The thicknesses of fibrotic scar tissue in the subcoracoid triangle and humeral side axillary recess as well as the grade of fibrotic scar tissue in the rotator interval were not significantly different between complete and partial type EIPMT. CONCLUSION: MRI enabled detection of EIPMT with substantial observer agreement. Patients with EIPMT show a high tendency for fibrotic scar tissue proliferation in the rotator interval.

Adolescent , Adult , Aged , Aged, 80 and over , Child , Female , Humans , Male , Middle Aged , Young Adult , Magnetic Resonance Imaging , Rotator Cuff/pathology , Shoulder/pathology , Tendons/pathology
Article in English | WPRIM | ID: wpr-228629


OBJECTIVE: To compare the accuracy between a three-dimensional (3D) indirect isotropic T1-weighted fast spin-echo (FSE) magnetic resonance (MR) arthrography and a conventional two-dimensional (2D) T1-weighted sequences of indirect MR arthrography for diagnosing rotator cuff tears. MATERIALS AND METHODS: The study was approved by our Institutional Review Board. In total, 205 patients who had undergone indirect shoulder MR arthrography followed by arthroscopic surgery for 206 shoulders were included in this study. Both conventional 2D T1-weighted FSE sequences and 3D isotropic T1-weighted FSE sequence were performed in all patients. Two radiologists evaluated the images for the presence of full- or partial-thickness tears in the supraspinatus-infraspinatus (SSP-ISP) tendons and tears in the subscapularis (SSC) tendons. Using the arthroscopic findings as the reference standard, the diagnostic performances of both methods were analyzed by the area under the receiver operating characteristic curve (AUC). RESULTS: Arthroscopy confirmed 165 SSP-ISP tendon tears and 103 SSC tendon tears. For diagnosing SSP-ISP tendon tears, the AUC values were 0.964 and 0.989 for the 2D sequences and 3D T1-weighted FSE sequence, respectively, in reader I and 0.947 and 0.963, respectively, in reader II. The AUC values for diagnosing SSC tendon tears were 0.921 and 0.925, respectively, for reader I and 0.856 and 0.860, respectively, for reader II. There was no significant difference between the AUC values of the 2D and 3D sequences in either reader for either type of tear. CONCLUSION: 3D indirect isotropic MR arthrography with FSE sequence and the conventional 2D arthrography are not significantly different in terms of accuracy for diagnosing rotator cuff tears.

Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Area Under Curve , Imaging, Three-Dimensional , Magnetic Resonance Imaging , ROC Curve , Retrospective Studies , Rotator Cuff/injuries , Sensitivity and Specificity , Shoulder Joint/injuries , Tendons/pathology
Artrosc. (B. Aires) ; 19(1): 62-66, mar. 2012.
Article in Spanish | LILACS | ID: lil-620440


Los trastornos del tendón de la porción larga del bíceps pueden existir en conjunto con otras patologías del hombro, se ha propuesto como causa de dolor en pacientes con lesión del manguito rotador. Una historia clínica detallada, examen físico exhaustivo y evaluación imagenológica, son necesarios para un correcto diagnóstico. El tratamiento conservador de la tendinopatia del bíceps es comúnmente aceptado como la primera línea de tratamiento. Este consiste en reposo, analgésicos, infiltraciones con corticoides y terapia física. La tenotomía y tenodesis del bíceps son los procedimientos quirúrgicos habituales para el manejo de la patología aislada de la porción larga del bíceps y asociada a rupturas del manguito rotador. Sin embargo, persiste la controversia sobre la superioridad de una técnica sobre la otra, al no haber evidencia estadística significativa.

Shoulder Joint/surgery , Arthroscopy/methods , Tendinopathy/surgery , Tendinopathy/pathology , Tendons/pathology , Tenodesis , Shoulder Pain
Indian J Cancer ; 2012 Jan-Mar; 49(1): 11-14
Article in English | IMSEAR | ID: sea-144545


Background: Resection of the anterior arch of the mandible leads to tongue fall and postoperative stridor because of the detachment of tongue musculature from the mandible. In this article, a simple method of tongue suspension is described which would prevent such complications and the need for tracheostomy. Settings and Design: This study was carried out on patients with oral cancer requiring resection of the anterior arch of the mandible as a part of the surgical resection at a tertiary centre. Materials and Methods: This study was performed on 32 patients with oral cancer requiring resection of the anterior arch of the mandible as a part of the surgical resection. Following an appropriate resection of the oral cancer (including the anterior mandibular arch) and neck dissection, a silk suture is used to loop the tongue musculature on either side to the intermediate tendon of the digastric muscle. Result: This technique of tongue suspension was used in 32 patients who required resection of the anterior mandibular arch for oral cancer. Prophylactic tracheostomy was not performed. One patient developed stridor at extubation and required temporary tracheostomy. All other patients could be successfully extubated within 12 h of surgery and none experienced postoperative stridor or sleep apnea. One other patient required temporary tracheostomy for pulmonary toilet as he developed aspiration pneumonitis related to nasogastric feed. Conclusion: This simple method of tongue suspension to the digastric tendon prevents postoperative tongue fall and obviates the need for tracheostomy in most instances.

Female , Humans , Male , Mandible/surgery , Mouth Neoplasms/pathology , Mouth Neoplasms/surgery , Muscles/surgery , Postoperative Period , Tendons/pathology , Tendons/surgery , Tongue/pathology , Tongue/surgery
Article in English | WPRIM | ID: wpr-39920


OBJECTIVE: To assess the feasibility of visualizing hand and foot tendon anatomy and disorders by Gemstone Spectral Imaging (GSI) high-definition CT (HDCT). MATERIALS AND METHODS: Thirty-five patients who suffered from hand or foot pain were scanned with GSI mode HDCT and MRI. Spectrum analysis was used to select the monochromatic images that provide the optimal contrast-to-noise ratio (CNR) for tendons. The image quality at the best selected monochromatic level and the conventional polychromatic images were compared. Tendon anatomy and disease were also analyzed at GSI and MRI. RESULTS: The monochromatic images at about 65 keV (mean 65.09 +/- 2.98) provided the optimal CNR for hand and foot tendons. The image quality at the optimal selected monochromatic level was superior to conventional polychromatic images (p = 0.005, p 0.05), compression (chi2 = 0.5, p > 0.05), absence (chi2 = 0, p > 0.05) and rupture (chi2 = 0, p > 0.05). GSI was significantly less sensitive than MRI in displaying tendon adhesion (chi2 = 4.17, p < 0.05), degeneration (chi2 = 4.17, p < 0.05), and tendinous sheath disease (chi2 = 10.08, p < 0.05). CONCLUSION: GSI with monochromatic images at 65 keV displays clearly the most hand and foot tendon anatomy and disorders with image quality improved, as compared with conventional polychromatic images. It may be used solely or combined with MRI in clinical work, depending on individual patient disease condition.

Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Foot/pathology , Hand/pathology , Magnetic Resonance Imaging , Musculoskeletal Diseases/diagnosis , Radiographic Image Enhancement , Tendon Injuries/diagnosis , Tendons/pathology , Tomography, X-Ray Computed/methods
Rev. bras. oftalmol ; 70(6): 378-383, nov.-dez. 2011. ilus, tab
Article in Portuguese | LILACS | ID: lil-612910


OBJETIVO: Estudar a frequência do espessamento do tendão muscular em pacientes com oftalmopatia de Graves buscando estabelecer correlações com as diferentes formas clínicas da doença. A diversidade clínica e laboratorial na oftalmopatia de Graves pode levar à confusão quanto ao diagnóstico, conduta e prognóstico. Os achados radiológicos variam desde o aumento isolado do tecido adiposo até o espessamento da musculatura extraocular, caracteristicamente poupando os tendões. Em 2004,no entanto, Ben Simon descreveu o espessamento do tendão muscular na oftalmopatia de Graves. MÉTODOS: Foram avaliados 20 pacientes, de ambos os sexos, com idades entre 20 e 80 anos, com formas clínicas designadas como :forma benigna (retração palpebral),forma intermediária (diplopia na posição primária do olhar) e forma maligna ou infiltrativa (sinais de comprometimento do nervo óptico).Todos os pacientes foram submetidos à tomografias computadorizadas de órbita. Os pacientes estavam eutiroideanos, há pelo menos um ano. Os padrões tomográficos foram estudados e divididos em dois grupos: com e sem espessamento dos tendões da musculatura extraocular. RESULTADOS: Uma relação estatisticamente significativa entre espessamento do tendão e a forma clínica intermediária foi encontrada (p <0,012). CONCLUSÃO: O espessamento do tendão extraocular, encontrado em 30 por cento dos pacientes com oftalmopatia de Graves, relaciona-se positivamente com a forma intermediária da doença, caracterizada pela presença de diplopia e que constitui um achado de grande valor clínico.

PURPOSE: The aim is therefore to study the frequency of tendon enlargment in Graves' ophthalmopathy, seeking to estabilish its clinical correlations. Clinical and laboratory diversity in Graves' Ophthalmopathy sometimes may mislead its diagnosis. Radiological findings are more reliable for the diagnosis of Graves' Ophthalmopathy. Since then, a number of patterns have been described. Extraocular muscle involvement in this pathology is considered as always sparing the tendons. In 2004, Ben Simon described extraocular muscles tendon enlargment in some patients with diplopia in Graves' orbitopathy. METHODS: 20 patients, aged between 20 and 80 years, of both sexes, designated as benign (eyelid retraction), intermediate(diplopia in primary sight position) and malignant or infiltrative(signs of optic nerve compromise) forms were evaluated by orbital tomography. All patients had already been euthyroidean for at least one year. Tomographic patterns were studied and divided into two groups: with or without extraocular muscle tendons enlargment. RESULTS: Statistically significant relationship was found between tendon enlargment and intermediate form (p<0.012). CONCLUSION: Extraocular tendon involvement present in 30 percent of the patients with Graves' ophthalmopathy, and is positively correlated to intermediary form of the disease, characterized by diplopia, a very important clinical landmark.

Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Tendons/pathology , Tendons/diagnostic imaging , Graves Disease/pathology , Graves Disease/diagnostic imaging , Oculomotor Muscles/pathology , Oculomotor Muscles/diagnostic imaging , Orbit/pathology , Orbit/diagnostic imaging , Tomography, X-Ray Computed , Anthropometry , Exophthalmos/diagnostic imaging
Artrosc. (B. Aires) ; 18(1): 30-36, mayo 2011.
Article in Spanish | LILACS | ID: lil-610344


Introducción: Las causas de ruptura de manguito rotador no son bien comprendidas. Existen diferentes teorías que explicarían su etiopatología. El objetivo del presente trabajo es describir un patrón histológico de normalidad y desarrollar un score histológico para evaluar lesiones agudas y crónicas del manguito rotador. Material y Métodos: Se realizaron once biopsias de espesor completo del manguito rotador en once pacientes con rupturas, no menores de 3 cm de longitud anteroposterior de distinto tiempo de evolución y 3 biopsias, en manguitos rotadores sin patología (Inestabilidad y Luxación Acromio-Clavicular). Se las sometió a estudios histológicos con hematoxilina-eosina, tricrómico de Masson (fibras colágenas), Giemsa (evaluar mastocitos), CD45 (leucocitos), CD68 (macrófagos), CD34 (endotelio vascular) y MIB-1 (índice proliferación celular). Se evaluaron los siguientes parámetros: Matriz extracelular (edema, orientación colágeno y metaplasia condroide), celularidad (fibroblastos, linfocitos, mastocitos y macrófagos), proliferación vascular y espesor de la membrana sinovial. Cada ítem fue cuantificado y se le coloco un valor de O (normal) a 3 (severo). Resultados: En las lesiones de menor tiempo de evolución, la característica primaria fue la desorganización de las fibras de colágeno, el aumento de la celularidad, a predominio de macrófagos y el edema. En las lesiones crónicas se observo un aumento del espesor de la membrana sinovial, metaplasia condroide y aumento de la celularidad a predominio de linfocitos. Conclusión: Los patrones histológicos varían, de acuerdo a la indemnidad del tendón y al tiempo de evolución de la ruptura. Relevancia Clínica: La posibilidad de reconocer diferentes patrones histológicos patológicos, en biopsias de manguitos rotadores con lesiones de distinto tiempo de evolución, nos permitirá, con un nivel de evidencia mayor, crear nuevas técnicas quirurgicas y mejorar los escenarios biológicos para el mejor tratamiento de esta patología.

Humans , Rotator Cuff/anatomy & histology , Rotator Cuff/injuries , Rotator Cuff/pathology , Shoulder Joint , Rupture , Tendons/pathology
Rev. chil. reumatol ; 26(2): 203-208, 2010. ilus, tab
Article in Spanish | LILACS | ID: lil-572124


La artritis psoriática es una enfermedad inflamatoria crónica y heterogénea que afecta articulaciones, tendones, entesis, piel y uñas. Indudablemente, a lo largo de los últimos años la ecografía se ha ido perfilando como un método de imágenes imprescindible en la práctica cotidiana reumatológica, no sólo por su bajo costo y su mayor sensibilidad respecto al examen físico, sino por la capacidad de detectar compromiso subclínico y permitir el monitoreo de la evolución de la enfermedad. El incesante crecimiento tecnológico orientado al diseño de equipos dotados de sondas de alta frecuencia y módulos power Doppler altamente sensibles permite actualmente apreciar alteraciones morfo-estructurales con una resolución inferior al décimo de milímetro, y detectar el mínimo flujo sanguíneo presente en los microvasos de los tejidos superficiales. No obstante estas ventajas, aún son pocos los estudios que demuestran la utilidad de la ecografía en la artritis psoriática. El objetivo principal de esta revisión es demostrar el potencial actual de la ecografía en el estudio de pacientes con artritis psoriática mediante la ilustración de alteraciones a nivel de articulaciones, tendones, entesis, piel y uñas.

Psoriatic arthritis (PsA) is a chronic and heterogeneous inflammatory disease that involves joints, tendons, enthesis, skin and nails. Without doubt, ultrasound has become a rapidly evolving technique that is gaining more and more importance among rheumatologists. The continuous technological advances in the field of ultrasound has allowed the development of equipment provided with high and variable frequency probes and very sensitive power Doppler, which permit both the detailed study (with resolution power of 0.1 mm) of morphostructural changes and the sensitive detection of blood flow, even in small vessels of superficial tissues. To date most of the studies have been aimed at investigating its capacity in the assessment of joints, tendons and entheses in psoriatic arthritis patients. Less attention has been paid to demonstrate the potential of ultrasound in the evaluation of skin and nails.The aim of this study is to show the main high frequency greyscale and power Doppler ultrasound findings in patients with psoriatic arthritis at joint, tendon, enthesis, skin and nail level.

Humans , Arthritis, Psoriatic , Ultrasonography, Doppler , Joints/pathology , Joints , Arthritis, Psoriatic/pathology , Tendons/pathology , Tendons , Nails/pathology , Nails
Article in English | WPRIM | ID: wpr-48766


The objectives of this study were: 1) to identify the ultrasonographic (US) abnormalities and 2) to compare the findings of physical examination with US findings in rheumatoid arthritis (RA) patients with shoulder pain. We studied 30 RA patients. Physical examination was performed systemically as follows: 1) area of tenderness; 2) range of passive and active shoulder motion; 3) impingement tests; 4) maneuvers for determining the location of the tendon lesions. US investigations included the biceps, the supraspinatus, infraspinatus, and subscapularis tendons; the subacromial-subdeltoid bursa; and the glenohumeral and acromioclavicular joints. Thirty RA patients with 35 painful and 25 non-painful shoulders were examined. The range of motion affected the most by shoulder pain was abduction. The most frequent US finding of shoulder joint was effusion in the long head of the biceps tendon. Among the rotator cuff tendons, subscapularis was the most frequently involved. Tendon tear was also common among non-painful shoulders. Physical examination used for the diagnosis of shoulder pain had low sensitivity and specificity for detecting abnormalities in the rheumatoid shoulder joint. In conclusion, US abnormalities showed frequent tendon tears in our RA patients. Physical examination had low sensitivity and specificity for detecting rotator cuff tear in the rheumatoid shoulder joint.

Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Arthritis, Rheumatoid/complications , Physical Examination/methods , Reproducibility of Results , Rotator Cuff/pathology , Shoulder/pathology , Shoulder Joint/diagnostic imaging , Shoulder Pain/etiology , Tendons/pathology
Maghreb Medical. 2006; 26 (381): 241-243
in French | IMEMR | ID: emr-78974


Giant cell tumors [GCT] are benign tumors of the tendon sheath, locally aggressive. Their prevalence comes only to 1.8 patients by one million inhabitants. They account for 18% of the benign tumors of hand and wrist. The location is in general unique. The affection can take two clinical forms. Thus, the GCT can be localized and appears under the aspect of an adherent nodule to a tendon, not painful and with slow growth. Elsewhere, it is diffuse and represents the equivalent in the sheaths or the serous purses of the pigmented villonodular synovitis. It affects young adults in general between the third and the fourth decade. Women seem more frequently affected than men. The location of predilection is fingers [80%]. Feet localization remains rare; we report one feet location. The aetiopathogenesis remains uncertain. Clinical expression of this entity is insidious. Standard radiographies are in general normal. MRI is the most performant exam for the analysis of the structure of synovial membrane nowadays. Biopsy confirms the diagnosis. The treatment is surgical and resection of the tumor must be complete with usually a favorable outcome. However local recurrence is frequent

Humans , Female , Tendons/pathology , Foot , Magnetic Resonance Imaging