1.
Translational and Clinical Pharmacology
; : 114-116, 2017.
Artículo
en Inglés
| WPRIM
| ID: wpr-87968
RESUMEN
Indoxyl sulfate, a protein-bound uremic toxin, leads to CKD (chronic kidney disease) progression and its complications through the activation of AhR (aryl hydrocarbon receptor) and RAS (renin-angiotensin system). Inhibition of these pathways may slow the development of CKD and CKD-associated complications.