RESUMEN
Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic syndrome characterized by elevated serum IgG4 concentrations and tumefaction or tissue infiltration by IgG4-positive plasma cells. We experienced a case of IgG4-RD involving multiple organs in a 64-year-old female who was referred for a suspected uroepithelial tumor. A mass biopsy confirmed dense lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. We discuss this case and review the literature to bring IgG4-RD to the attention to clinicians because it responds dramatically well to steroid therapy and should be kept in mind as a differential diagnosis to avoid unnecessary surgery.
Asunto(s)
Femenino , Humanos , Persona de Mediana Edad , Biopsia , Diagnóstico Diferencial , Inmunoglobulina G , Inmunoglobulinas , Riñón , Células Plasmáticas , Esclerosis , Procedimientos InnecesariosRESUMEN
Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic syndrome characterized by elevated serum IgG4 concentrations and tumefaction or tissue infiltration by IgG4-positive plasma cells. We experienced a case of IgG4-RD involving multiple organs in a 64-year-old female who was referred for a suspected uroepithelial tumor. A mass biopsy confirmed dense lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. We discuss this case and review the literature to bring IgG4-RD to the attention to clinicians because it responds dramatically well to steroid therapy and should be kept in mind as a differential diagnosis to avoid unnecessary surgery.
Asunto(s)
Femenino , Humanos , Persona de Mediana Edad , Biopsia , Diagnóstico Diferencial , Inmunoglobulina G , Inmunoglobulinas , Riñón , Células Plasmáticas , Esclerosis , Procedimientos InnecesariosRESUMEN
Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic syndrome characterized by elevated serum IgG4 concentrations and tumefaction or tissue infiltration by IgG4-positive plasma cells. We experienced a case of IgG4-RD involving multiple organs in a 64-year-old female who was referred for a suspected uroepithelial tumor. A mass biopsy confirmed dense lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. We discuss this case and review the literature to bring IgG4-RD to the attention to clinicians because it responds dramatically well to steroid therapy and should be kept in mind as a differential diagnosis to avoid unnecessary surgery.
Asunto(s)
Femenino , Humanos , Persona de Mediana Edad , Biopsia , Diagnóstico Diferencial , Inmunoglobulina G , Inmunoglobulinas , Riñón , Células Plasmáticas , Esclerosis , Procedimientos InnecesariosRESUMEN
BACKGROUND/AIMS: The ballooning time in endoscopic papillary large balloon dilation (EPLBD) remains controversial. The aim of this study was to evaluate the significance of the ballooning time comparing an immediate balloon deflation method with a conventional ballooning time of > 45 seconds. METHODS: Between January 2010 and December 2010, 126 patients with bile duct stones treated with EPLBD and endoscopic sphincterotomy were divided according to the ballooning time: the immediate deflation group (n=56) and the conventional inflation group (ballooning time 45s to < 60s) (n=70). RESULTS: The overall success rate and the success rate of the first attempt of ERCP (endoscopic retrograde cholangio-pancreatography) were 96.4% (54/56) and 80.4% (45/56) in the immediate group and 97.1% (68/70) and 77.1% (54/70) in the conventional inflation group. There were no statistically significant differences in the overall success and the first attempt of ERCP success rate (p=0.99, p=0.66). The frequency of mechanical lithotripsy was 0% in the immediate deflation group and 7.1% in the conventional inflation group (p=0.065). Complications occurred in 3.6% (2/56) patients in the immediate deflation group and 8.6% (4/70) patients in the conventional inflation group (p=0.298). CONCLUSIONS: The ballooning time in EPLBD does not affect the outcomes of the treatment for bile duct stones. And the feasibility of the immediate deflation method in EPLBD is acceptable.
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Humanos , Conductos Biliares , Colangiopancreatografia Retrógrada Endoscópica , Coledocolitiasis , Inflación Económica , Litotricia , Esfinterotomía EndoscópicaRESUMEN
An epidermoid cyst arising from intrapancreatic accessory spleen (ECIPAS) is a rare disease. Most patients with an ECIPAS are detected incidentally and could be misdiagnosed as a pancreatic cystic neoplasm such as mucinous cystic neoplasm (MCN) or intraductal p ancreatic mucinous neoplasm (IPMN). We described an ECIPAS with high cystic fluid carcinoembryonic antigen (CEA), which was misdiagnosed as a MCN of pancreas. Fifty one-year-old female was presented with a 2 cm sized non-enhancing pancreas cystic mass on the outside CT scan. Endoscpic ultrasonography (EUS) guided aspiration was performed. It showed a 2.3 x 1.9 cm unilocular cyst nearby 1.6 x 1.1 cm homogenous hypoechoic mass in pancreas tail, and cystic fluid CEA was 1564.18 ng/mL. On the basis of EUS results with elevated fluid CEA level, the presumptive diagnosis is likely to MCN of pancreas, and she underwent a laparoscopic distal pancreatectomy. The final pathology was the epidermal cyst in the intrapancreatic accessory spleen.
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Femenino , Humanos , Antígeno Carcinoembrionario , Diagnóstico , Quiste Epidérmico , Mucinas , Páncreas , Pancreatectomía , Quiste Pancreático , Patología , Enfermedades Raras , Bazo , Tomografía Computarizada por Rayos X , UltrasonografíaRESUMEN
PURPOSE: Moyamoya disease is a chronic cerebrovascular illness characterized by bilateral stenoses or occlusions of the arteries around the circle of Willis with prominent collateral circulation. We studied 36 children and adolescents with Moyamoya disease to evaluate the clinical features and outcomes. METHODS: Records were reviewed of 36 pediatric patients admitted at the Busan Paik Hospital for Moyamoya disease between January 2000 and July 2007. The clinical records were reviewed in terms of the patient profiles, imaging findings, surgical techniques, and pathologic findings. RESULTS: Overall clinical features, responses to treatment and outcome were nearly same as those of other previous reports in Korea as well as the other countries. The mean age of onset was 8 years and 5 months and the ratio of male to female was 1:1.2. Ischemia was more often than infarction(5.6: 1). Half of the patients had conservative therapy and 17 cases(47%) were treated with EDAS. CONCLUSION: The clinical features of childhood Moyamoya disease are similar to the result from other studies in Korea.
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Adolescente , Niño , Femenino , Humanos , Masculino , Edad de Inicio , Arterias , Círculo Arterial Cerebral , Circulación Colateral , Constricción Patológica , Isquemia , Corea (Geográfico) , Enfermedad de MoyamoyaRESUMEN
Restrictive dermopathy is a rare autosomal recessive disorder in which rigidity or tautness of the skin from the second trimester causes a fetal akinesia deformation sequence (FADS) and early death. Characteristic features include taut skin with prominent subcutaneous vessels, widely open fontanelles and cranial sutures, distinctive facies, flexion contractures, pulmonary hypoplasia, sparse eyelashes and and eyebrows, thin dysplastic clavicles. The histologic abnormalities of the skin are located in a thin dermis, consisting of compactly arranged collagen fibers, scanty elastic fiber. The dermoepidermal junction is flat, and epidermal appendages are absent, miniaturized or immature. The presence of adipose tissue may be increased. We report on the first Korean case of restrictive dermopathy with typical clinical features and histological findings.
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Femenino , Humanos , Embarazo , Tejido Adiposo , Clavícula , Colágeno , Contractura , Suturas Craneales , Dermis , Tejido Elástico , Cejas , Pestañas , Facies , Segundo Trimestre del Embarazo , PielRESUMEN
Leukocytosis and neutrophilia is common during the acute phase of Kawasaki disease whereas leukopenia is not common and severe neutropenia is rare. Severe neutropenia is defined as absolute neutrophil count less than 500/mm3. There are only few publicatons reporting of atypical Kawasaki disease with severe neutropenia. We report a case of atypical Kawasaki disease with severe neutropenia.
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Leucocitosis , Leucopenia , Síndrome Mucocutáneo Linfonodular , Neutropenia , NeutrófilosRESUMEN
PURPOSE: To compare the clinical and radiological findings of orbital pseudotumor with those of orbital lymphoma. MATERIALS AND METHODS: The clinical and radiological features of 12 orbital pseudotumors were compared with those of 17 orbital lymphomas, the nature of all lesions being confirmed by tissue biopsy. Twenty-four CT scans and nine MR images were retrospectively reviewed and compared, with special focus on the location of a tumor in the orbit, the invasion of periorbital structures, tumor margin, bilaterality, and signal intensity. The initial symptoms at admission were also classified and compared. RESULTS: In 50% of cases, orbital pseudotumors were located in both extraconal and intraconal space; 75% involved two or more extraocular muscles, and 33% involved the optic nerve. Margins were either infiltrative (75%) or ill-defined (92%). As for orbital lymphomas, 64% occupied extraconal space, invading one or less extraocular muscle (76%) and conjunctiva (29%). Seventy-one percent had a sharp margin, and 65% were lobulated or round. In pseudotumors, orbital pain and visual loss were major symptoms, while in lymphomas a painless orbital mass was the initial symptom. CONCLUSION: CT or MR image analysis of lesion location, margin, and the involvement of adjacent extra-ocular muscle or optic nerves may help differentiate between orbital lymphoma and orbital pseudo tumor.
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Biopsia , Conjuntiva , Linfoma , Músculos , Nervio Óptico , Órbita , Seudotumor Orbitario , Estudios Retrospectivos , Tomografía Computarizada por Rayos XRESUMEN
PURPOSE: To determine the minimal threshold ADC ratio suggesting reversible ischemia in a temporary model of MCAO. MATERIALS AND METHODS: Seven Korean cats weighing 3-3.5 kg were used as a temporary model of MCAO. The MCA was occluded for 1 hour, and diffusion-weighted images (DWI), and ADC and regional cerebral blood volume (rCBV) maps, were obtained at 1, 3, 6 and 24 hours after reperfusion using a 1.5T MR unit. The Cats were sacrificed 24 hours after imaging. Triphenyl tetrazolium chloride (TTC) staining of brain slices was performed, and DWI images and TTC-stained brain slices were compared with the naked eye. Reversible ischemia was defined as the area of high signal intensity at 1-hour DWI that normalized at follow-up DWI and in which TTC staining was normal. Using the ADC image obtained at 1 hour after reperfusion, 60 ADC ratios were obtained in the periphery of the infarct and reversible ischemia. Tissue survival showing normal TTC staining was used for final determination. The sensitivity and specificity of each ADC ratio was obtained and an ROC curve was plotted. RESULTS: Five of seven cats showed the reversible ischemia. An area of high signal intensity was seen on DWI images obtained 1 hour after reperfusion, and this improved at follow-up imaging. The distribution of the ADC ratio in the periphery of the infarct core was 0.71-0.81, and in the periphery of reversible ischemia it was 0.79-0.93. The ADC ratio of 0.80 obtained 1 hr after reperfusion predicted the survival of the ischemic tissue with 93% sensitivity and 90% specificity. The ADC ratio of the reversible ischemia was 0.82+/-0.03 at 1 hour after reperfusion, and this was higher than that of the infarct, which was 0.74+/-0.03. CONCLUSION: The minimal threshold ADC ratio suggesting reversible ischemia in this temporary model of MCAO was 0.80.
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Animales , Gatos , Volumen Sanguíneo , Encéfalo , Isquemia Encefálica , Difusión , Estudios de Seguimiento , Isquemia , Reperfusión , Curva ROC , Sensibilidad y Especificidad , Supervivencia TisularRESUMEN
Research Institute of Radiological Science, Yonsei University The trigeminal nerve is the largest of the cranial nerves and has both sensory and motor functions. It can be divided into proximal (brainstem, preganglionic, gasserian ganglion, and cavernous sinus) and distal (extracranial opthalmic, maxillary, and mandibular) segments. Patients with trigeminal neuropathy present with a wide variety of symptoms, and lesions producing those symptoms may occur anywhere along the protracted course of the trigeminal nerve, from its distal facial branches to its nuclear columns in the brainstem. The purpose of this article is to illustrate the normal anatomy of the trigeminal nerve and associated various pathologic conditions. These are arranged anatomically according to their site of interaction with it.
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Humanos , Academias e Institutos , Tronco Encefálico , Nervios Craneales , Imagen por Resonancia Magnética , Ganglio del Trigémino , Nervio Trigémino , Enfermedades del Nervio TrigéminoRESUMEN
Purpose: To describe two different methods of "double-catheter" techniques for the treatment of wide-necked intracranial aneurysms. MATERIALS AND METHODS: Using two microcatheters simultaneously, we treated two wide-necked ophthalmic aneurysms and one wide-necked basilar bifurcation aneurysm. In the two cases of ophthalmic aneurysms, the two microcatheters were placed in the aneurysm sac, thus allowing two coils to be braced across the aneurysmal neck before either was detached. In the case of the basilar bifurcation aneurysm, a microcatheter was placed in the posterior cerebral artery (PCA), and another within the aneurysm lumen. When making the first frame with a GDC, we tried to ensure that the frame of the coil and the microcatheter in the PCA did not over-lap. Then, through the microcatheter positioned at the PCA, angiography was performed and flow pattern and dye-disappearance time were evaluated. Subsequent coils were introduced, but in order to preserve PCA flow, not beyond the frame of the first coil. RESULTS: All three aneurysms were successfully embolized without parent artery compromise and the patients were discharged in good neurological condition. CONCLUSION: The "double-catheter" technique can provide a valuable option for treating wide-necked aneurysms, especially when 'balloon remodeling' is not feasible and/or the relationship between the aneurysmal neck and adjacent parent artery cannot be ascertained.
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Humanos , Aneurisma , Angiografía , Arterias , Tirantes , Aneurisma Intracraneal , Cuello , Padres , Anafilaxis Cutánea Pasiva , Arteria Cerebral PosteriorRESUMEN
PURPOSE: To investigate the findings of diffusion-weighted MR imaging in patients with transient ischemic at-tacks (TIA). MATERIALS AND METHODS: Between August 1996 and June 1999, 41 TIA patients [M:F = 28:13, mean age 57 (range, 27 -75) years] with neurologic symptoms lasting less than 24 hours underwent diffusion-weighted MR imaging. The time interval between the onset of symptoms and MR examination was less than one week in 29 patients, from one week to one month in eight, and undetermined in four. Conventional MR and DWI were compared in terms of location of infarction and lesion size (3 cm), and we also determined the anatomical vascular territory of acute stroke lesions and possible etiologic mechanisms. RESULTS: The findings of DWI were normal in 24/41 patients (58.5%), while 15 (36.6%) showed acute ischemic lesions. The other two showed old lacunar infarcts. All acute and old DWI lesions were revealed by conven-tional MR imaging. Among the 15 acute stroke patients, seven had small vessel lacunar disease. In three pa-tients, the infarction was less than 1 cm in size. Six patients showed large vessel infarction in the territory of the MCA, PCA, and PICA; the size of this was less than 1 cm in three patients, 1 -3 cm in two, and more than 3 cm in one. In two patients, embolic infarction of cardiac origin in the territory of the MCA and AICA was diagnosed. CONCLUSION: The possible mechanism of TIA is still undetermined, but acute lesions revealed by DWI in TIA patients tend, in any case, to be small and multiple.
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Humanos , Difusión , Infarto , Ataque Isquémico Transitorio , Imagen por Resonancia Magnética , Manifestaciones Neurológicas , Anafilaxis Cutánea Pasiva , Pica , Accidente Cerebrovascular , Accidente Vascular Cerebral LacunarRESUMEN
PURPOSE: To compare hippocampal and neocortical metabolite ratios using single-voxel proton MR spectroscopy with different echo times in patients with complex partial seizure. MATERIALS AND METHODS: Using a GE Signa 1.5 T scanner with STEAM and PRESS sequences, automated single voxel proton MRS was used to determine metabolite ratio differences in the hippocampus and neocortex of nine complex partial seizure patients [mesial temporal sclerosis (n=5), status epilepticus (n=1), tumor (n=1), cortical dysplasia (n=1), occipital lobe epilepsy (n=1)]. A total of 20 examinations were performed in the region of the hippocampus (n=17), temporal neocortex (n=1), and parieto-occipital gray matter (n=1). Voxel size range was 5.2 -17.4 cm 3. The calculated creatine (Cr) peak was employed as an internal reference and the relative ratio of N-acetylaspartate (NAA) and choline (Cho) was calculated for both short and long echo times using an automated PROBE/SV (GE Medical Systems) package. Each NAA/Cho ratio obtained using both PRESS and STEAM techniques was compared by means of statistical analysis (paired Student t-test). RESULTS: Using PRESS (long TE, 272 ms), NAA/Cho ratios were successfully calculated in 16 of 20 examinations; in four this was not possible due to noise levels of the Cr and Cho peaks. Using STEAM (short TE, 30 ms) NAA/Cho ratios were successfully calculated in 19 of 20 examinations; in one, the Cho peak could not be measured. Using PRESS and STEAM, mean and standard deviations for the NAA/Cho ratio were 1.22 +/-0.50 and 1.16 +/-0.36, respectively. There were no statistically significant differences in this ratio between the short and long TE method (p <0.01). CONCLUSION: In complex partial seizure patients, no significant metabolite differences were found between short and long echo times of single voxel proton MR spectroscopy. The metabolite ratio at different echo times can be reliably obtained using this simplified and automated PROBE/SV quantitation method.
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Humanos , Colina , Creatina , Epilepsias Parciales , Hipocampo , Espectroscopía de Resonancia Magnética , Malformaciones del Desarrollo Cortical , Neocórtex , Ruido , Protones , Esclerosis , Convulsiones , Estado Epiléptico , VaporRESUMEN
PURPOSE: To determine the usefulness of repeat diffusion-weighted imaging (DWI) during the acute ischemic stroke stage for the prediction of evolving stroke and clinical course. MATERIALS AND METHODS: Fifteen patients with acute ischemic stroke in MCA territory [24 hours, 10 patients; M:F=9:6; age 28 -75 (mean, 61) years] were involved in this prospective study. All patients underwent initial DWI, follow-up DWI (within two weeks of the first attack) and T2WI (2 -5 months later to assess final infarction territory). The National Institute of Health Stroke Scale (NIHSS) was used for clinical evaluation. 'Evolving stroke' was defined as progression of NIHSS after admission. For statistical analysis, Fisher's exact test was used and a p value<0.05 was considered significant. RESULTS: In six patients (40%), the diagnosis was evolving stroke. In four of these (67%), follow-up DWI showed that the infarction territory was more extensive. Evolving stroke occurred 24 -72 hours after the onset of symptoms. DWI obtained 72 hours after onset showed that one patient had developed new infarction. Patients in whom enlarged infarction territory was seen on follow-up DWI showed progression of NIHSS within three days of onset, while those in whom follow-up DWI demonstrated no change showed an improved NIHSS (p < 0.05). Those who underwent initial DWI within 24 hours of onset showed larger infarction territory on follow-up DWI than those who underwent initial DWI later than this (p < 0.05). CONCLUSION: Repeat DWI during the acute ischemic stroke stage might be useful for the evaluation of evolving stroke.
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Humanos , Diagnóstico , Estudios de Seguimiento , Infarto , Estudios Prospectivos , Accidente CerebrovascularRESUMEN
PURPOSE: The aim of our study was to evaluate the usefulness of high-resolution CT scans in addition tohelical CT for characterizing a solitary pulmonary nodule. MATERIALS AND METHODS: Our study included 49 patientswith a solitary pulmonary nodule ; in each patient this was evaluated by both additional high-resolution CT andhelical scanning. Images were evaluated by three independent observers, each of whom read them twice : initiallywith helical CT images only and then with helical images plus high-resolution CT images. After analysis, theobservers recorded the following : histologic diagnosis, benignancy or malignancy of a nodule, and confidence intheir diagnosis (three scales). RESULTS: In differentiating benign and malignant nodules, the accuracy of helicalscans only was 75% (110/147 readings) whereas that of helical plus high-resolution CT scans was 82% (121/147readings) (p=0.001). Correct histologic diagnosis was made in 47% of cases (69/147 readings) when helical scansonly had been evaluated and in 48% of cases (71/147 readings) for which both helical and high-resolotion CT scanswere available (p=0.815). Diagnosis was more often highly confident on the basis of additional high-resolution CTscans (25%) than helical scans only (5%) (p=0.001) . CONCLUSION: By enhancing differential diagnosticaccuracy between benign and malignant nodules and by increasing confidence in the histologic diagnosis of apulmonary nodule, additional high-resolution CT scans are valuable for the evaluation of a solitary pulmonarynodule.
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Humanos , Diagnóstico , Nódulo Pulmonar Solitario , Tomografía Computarizada Espiral , Tomografía Computarizada por Rayos XRESUMEN
PURPOSE: To demonstrate the MR findings of large Schmorl's nodes(>1 cm). Method and Materials: Six hundredpatients underwent MRI and the results were retrospectively analysed. Eleven patients(1.83%) had 12 largeSchmorl's nodes. We analyzed the size, contour, location, signal changes and enhancement of these, as well asmarrow changes in adjacent vertebral bodies. RESULTS: Twelve large Schmorl's nodes were found in eleven of 600patients(1.83%) with a mean age of 46.1 years and a female : male ratio of 4 : 7. Their mean size was 1.35 cm(AP)x 0.99 cm(height) x 1.23 cm(transverse), and they were observed at various sites, namely lower(n=7) and upperend-plate locations(n=5). Central locations(n=8) on end-plates were most common. A semi-lunar appearance was notedin seven cases, and in most, a well-demarcated irregular margin was seen. All large Schmorl's nodes were enhanced; peripheral forms(n=8) were more common than diffuse(n=4). Adjacent discs showed no intranuclear enhancement butin seven cases there was flat-contoured enhancements in the annulus fibrosus. In disks with large Schmorl's nodes,degeneration was noted on T2WI regardless of the degree of diskal herniation. In nearly all cases, signalintensity on T1WI was low, but on T2WI, this was variable. Large Schmorl's nodes showed characteristic marrowchange in adjacent vertebral bodies ; the most common pattern was fatty and sclerotic(n=8). Especially onT1-weighted axial images, target appearances were visible in ten cases. CONCLUSION: MR findings of Schmorl'snodes will be very useful for differentiating nodes from other vertebral or diskal lesions, especially spondylitiscombined with diskitis or vertebral body tumor.
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Femenino , Humanos , Masculino , Discitis , Imagen por Resonancia Magnética , Estudios RetrospectivosRESUMEN
PURPOSE: We evaluated the MRI finding of pachymeningeal enhancement in patients with intracranial hypotensionand head trauma with particular attention to differential findings and change in follow-up study, and in order tosupport the knowledge about the pathophysiology of dural enhancement. METHODS AND MATERIALS: The findings ofenhanced brain MRI of fifteen patients who showed diffuse pachymeningeal enhancement were retrospectivelyexamined. Seven of fifteen patients were finally diagnosed as spontaneous intracranial hypotension(SIH). Eight offifteen patients had a recent history of head trauma. We analyzed the shape, thickness, continuity and extent ofdural enhancement, and the others concerned with positive MR findings. We also analyzed findings suggesteddisplacement of brain parenchyma- displacement of the iter and cerebellar tonsil, and flattening of the anterioraspect of the pons-. Four of seven patients with SIH and four of eight patients with head trauma, underwentfollow-up MRI. In the follow-up study, the presence of resolving pachymeningeal enhancement and symptomimprovement was investigated. RESULTS: In all cases of SIH, the dura showed diffuse, even 3(1mm thick, global andcontiguous enhancement along both cerebral convexities, both tentoria, and the falx. Displacement of the iter wasnoted in six cases and flattening of the anterior aspect of the pons in five. Displacement of the cerebellartonsil was noted in one case. Five of seven cases showed small amount of subdural fluid collection. In all casesof head trauma, the dura was enhanced diffusely and asymmetrically, and showed no contiguity. Its distribution wasconsistent with the locations of traumatic lesions. Displacement of the iter was noted in one case. In four casesof SIH, clinical symptoms had improved, and three showed complete resolution of dural enhancement, in one patientcontinuously showed partial dural enhancement. Four cases of head trauma showed complete resolution of duralenhancement. CONCLUSIONS: Reversible diffuse pachymeningeal enhancement and additional findings in brain MRI ofSIH and head trauma are valuable for differenciation from other irreversible pathological conditions related topachymeningeal enhancement and to support the knowledge about pathophysiology of dural enhancement.
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Humanos , Encéfalo , Traumatismos Craneocerebrales , Estudios de Seguimiento , Cabeza , Hipotensión Intracraneal , Imagen por Resonancia Magnética , Tonsila Palatina , PuenteRESUMEN
PURPOSE: The purpose of this study was to evaluate the incidcnce of extrapericardial fat in the left cardiacborder, and with regard to left extrapericardial fat, to correlate chest radiographs with CT scans. MATERIALS AND METHODS: This study involved 132 consecutive patients who underwent chest PA and lateral radiographs, and chestCT scans. According to the results of chest PA radiograph, patients were divided into three groups: those with aclear left cardiac border; those with an indistinct left cardiac border; and those with an indistinct left cardiacborder with increased density; cardiophrenic angle, as seen on lateral radiograph, the presence of increaseddensity in the anterior cardiophrenic angle, as seen on lateral radiograph radiographs was evaluated. On the basisof the results of CT scanning, patients were classified into four groups according to the amount of leftextrapericardial fat: negative, minimum, moderate, and maximum. Left extrapericardial fat, as seen on CT, wascorrelated with the conspicuity of left cardiac border seen on PA radiograph and the presence of increased densityin the anterior cardiophrenic angle, as seen on lateral radiograph. RESULTS: On CT, left extrapericardial fat wasobserved in 51 patients (38.6%). In 38 of these (28.8%), the amount was minimal, in 12 (9.1%), it was moderate,and in one (0.8%), it was maximal. On posteroanterior chest radiograph, clear, indistinct, and indistinct andincreased density of the left cardiac border was seen in 89 (67.4%), 28 (21.2%), and 15 cases (11.4%),respectively. On lateral radiograph, increased density of the anterior cardiophrenic angle was seen in 115 cases(87.1%) but in 17 (12.9%), increase density was not apparent. There was significant correlation between chestradiographs and CT(p<0.001) (sensitivity: 53%; specificity: 100%; positive predictive value: 100%; negativepredictive value: 84%). CONCLUSION: The conspicuousness of the left cardiac border, as seen on PA chestradiograph, correlated with the presence of left extrapericardial fat, as seen on CT, and was related to theamount of left extrapericardial fat. Increased density of the anterior cardiophrenic angle, as seen on lateralradiographs, correlated with the presence of left extrapericardial fat on CT, but the absence of increased densityon lateral radiograph corresponds to the absence or a minimal amount of left extrapericardial fat, as seen on CT.
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Humanos , Radiografía Torácica , Sensibilidad y Especificidad , Tórax , Tomografía Computarizada por Rayos XRESUMEN
Lipoma is a common benign neoplasm, but lipoma arising from the pleura is rare; it is composed of mature adipose tissue and occasionally fibrous stroma. The tumor shows characteristic radiographic and CT features of pleural mass, and the lesion is homogeneous and low density, with CT numbers indicating fat. The mass was removed by surgery and confirmed as a lipoma originating from the parietal pleura.