1.
Acta Pharmaceutica Sinica
; (12): 532-542, 2024.
Artículo
en Chino
| WPRIM
| ID: wpr-1016612
RESUMEN
Natural products are important sources for the discovery of anti-tumor drugs. Evodiamine is the main alkaloid component of the traditional Chinese herb Wu-Chu-Yu, and it has weak antitumor activity. In recent years, a number of highly active antitumor candidates have been discovered with a significant progress. This article reviews the research progress of evodiamine-based antitumor drug design strategies, in order to provide reference for the development of new drugs with natural products as leads.