La profesora Raquel Pérez González y el signo de la muela de cangrejo / Professor Raquel Pérez González and crab claw sign

La Dra. Raquel Pérez González, más conocida entre colegas, alumnos y compañeros de trabajo por "la profe Raquel", obtuvo el título de Medicina en el año 1976. Comenzó por vía directa la residencia de Radiología y obtuvo el título de especialista de primer grado en 1979. Se convirtió así, el Hospital Militar Central "Dr. Carlos J. Finlay", en la cuna de su formación profesional y en años posteriores, en la casa que la vio crecer, especialmente como maestra de numerosas generaciones de radiólogos e imagenólogos. Hoy reposan en el jardín del Departamento de Imagenología, parte de sus cenizas, custodiadas por el amor que fue capaz de cultivar. En el 2016, una paciente femenina de 60 años de edad, acudió a la consulta de gastroenterología, con dolor abdominal difuso. La radiografía de abdomen simple, anteroposterior, en posición acostado mostró, una imagen en "muela de cangrejo", visible al tomar el aire dentro del hemicolon transverso izquierdo, como contraste, el cual bordea por ese lado parcialmente, una opacidad de partes blandas, que se extiende desde el mesogastrio, hasta la fosa ilíaca derecha, donde se observa el signo del menisco. Los estudios de imágenes realizados, evidenciaron signos radiológicos típicos de invaginación por causa tumoral maligna. En varias ocasiones, la profesora Raquel utilizó la imagen de este caso, como pregunta en exámenes de promoción de residentes. La publicación de este caso constituye un homenaje a quien será siempre un paradigma de docente.

Dr. Raquel Pérez González, better known among colleagues, students and co-workers as "professor Raquel", obtained her degree in Medicine in 1976. She began her Radiology residency directly and obtained the title of first-class specialist degree in 1979. Thus, the Central Military Hospital "Dr. Carlos J. Finlay" is the cradle of her professional training and in later years, in her home where she saw her grow up, especially as a teacher to numerous generations of radiologists and imaging scientists. Today, part of her ashes rest in the garden of the Imaging Department, guarded by the love that she was able to cultivate. In 2016, a 60-year-old female patient attended the gastroenterology clinic with diffuse abdominal pain. The simple, anteroposterior abdominal x-ray, in the lying position, showed a "crab claw" image, visible when breathing into the left transverse hemicolon, as contrast, which partially borders on that side, a soft tissue opacity, which extends from the mesogastrium to the right iliac fossa, where the meniscus sign is observed. The imaging studies performed showed typical radiological signs of invagination due to malignant tumor. On several occasions, Professor Raquel used the image of this case as a question in resident promotion exams. The publication of this case constitutes a tribute to someone who will always be a paradigm of a teacher.

Inteligência artificial aplicada aos exames de imagem odontológicos: uma revisão da literatura / Artificial intelligence applied to dental imaging: a review

Objetivo: investigar a literatura relacionada à aplicação e desempenho da Inteligência Artificial (IA) em exames de imagem odontológicos. Revisão de literatura: foram incluídos 70 trabalhos experimentais e revisões sistemáticas da literatura, publicados em inglês, no período entre 2018 e 2021, que analisaram a aplicabilidade da IA na detecção automática de: pontos cefalométricos, lesões de cárie, lesões apicais, perda óssea periodontal, sistemas de implantes, cistos e tumores odontogênicos, osteoporose, sinusite maxilar, terceiros molares e canal mandibular, ateromas em carótida, fratura radicular vertical, osteoartrite em articulação temporomandibular, avaliação de morfologia radicular e numeração dentária. Resultados:58,73% dos trabalhos analisados mostrou acurácia diagnóstica acima de 80% com a utilização de IA. Discussão: A maior limitação encontrada foi em relação à aquisição de amostras em quantidade suficiente para treinamento e teste dos modelos, já que imagens radiográficas têm sua disponibilidade limitada por questões éticas e legais relativas aos pacientes e Instituições. A falta de padronização na segmentação e processamento das imagens foi outro fator a influenciar os resultados obtidos, dificultando comparação e generalização. Apesar disso, diversos estudos apresentaram sugestões ou possíveis aperfeiçoamentos para pesquisas futuras, de forma a reduzir estas limitações. Conclusão: A aplicação da IA no diagnóstico por imagens mostrou-se promissora nas diversas áreas pesquisadas, com desempenhos muito semelhantes ou mesmo superiores, muitas vezes, ao desempenho dos profissionais humanos. Contudo, para a legitimação de sua utilização como parte do fluxo de trabalho na clínica, limitações ainda presentes devem ser superadas, especialmente no treinamento dos algoritmos para obtenção de melhores valores de acurácia.

Aim:to investigate the literature related to the application and performance of Artificial Intelligence (AI) in the analysis of dental imaging. Literature review: 70 experimental studies and systematic literature reviews published in English between 2018 and 2021 were included, which analyzed the applicability of AI models in the automatic detection of the following: cephalometric landmarks, dental caries, periapical diseases, alveolar bone loss, dental implant, odontogenic cysts and tumors, osteoporosis, maxillary sinusitis, third molars and mandibular canal, carotid atheromas, vertical root fracture, osteoarthritis in temporomandibular joint, evaluation of root morphology and numbering of dental elements. Results: 58.73% of the analyzed studies showed diagnostic accuracy above 80%.Discussion:the greatest methodological limitation was the acquisition of samples in sufficient quantity for training and testing phases, since radiographic images are limited to their availability due to ethical and legal issues related to patients and institutions. Lack of standardization in the segmentation and image processing was another factor to influence the results, which was difficult to compare and generalize. Despite this, several studies presented suggestions or possible improvements for future research, in order to reduce the impact of these limitations. Conclusion:the investigation of the applicability of AI in theanalysis of dental radiographic images seems to be still in its early days. The implementation of AI tools as radiologists'auxiliaries in their daily practice depends on overcoming the limitations of current studies and obtaining better diagnostic accuracy indices in future evaluations.

Comparación de las características anatómicas del conducto nasopalatino en pacientes dentados y desdentados mediante tomografía computarizada de haz cónico. Lima 2018-2020 / Comparison of the anatomic characteristics of the nasopalatine duct in toothed and edentulous patients by cone beam computed tomography. Lima 2018-2020

Objetivo : Comparar las características anatómicas del CNP en pacientes dentados y desdentados mediante Tomografía Computarizada de Haz Cónico (TCHC) del Servicio de Radiología Bucomaxilofacial realizadas en el Centro Dental Docente de la Universidad Peruana Cayetano Heredia. Material y métodos : Se evaluaron todas las TCHC adquiridas entre los años 2018 y 2020, que cumplan con ciertos criterios; donde se comparó las características anatómicas del CNP. Los datos fueron registrados en una base de datos, luego representados en tablas. Resultados : Se evaluaron 216 volúmenes tomográficos (VT), divididos en dos grupos: dentados y desdentados. La forma cilíndrica y la forma de canal único fueron las más encontradas en ambos grupos. La longitud y la distancia fueron mayores en pacientes dentados, no se encontró asociación con relación al diámetro; la inclinación fue mayor en pacientes desdentados, encontrándose asociación con relación a la inclinación entre los grupos comparados. Conclusiones : Se encontraron múltiples diferencias anatómicas del CNP entre los pacientes dentados y desdentados evaluados con TCHC con relación al sexo y la edad.

Objective : To compare the anatomical characteristics of the NPC in dentate and edentulous patients using Cone Beam Computed Tomography (CBCT) of the Bucomaxillofacial Radiology Service performed at the Centro Dental Docente of the Universidad Peruana Cayetano Heredia. Material and methods : All TCHC acquired between the years 2018 and 2020, which meet certain criteria, were evaluated; where the anatomicals characteristics of the CNP were compared. The data were recorded in a database, then represented in tables. Results : 216 tomographic volumes were evaluated, divided into two groups: dentate and edentulous. The single cylindrical shape and the single channel shape were the most found in both groups. The length and distance were greater in dentate patients, no association was found in relation to the diameter, the inclination was greater in edentulous patients, finding an association in relation to the inclination between the compared groups. Conclusions : Multiple anatomical differences of the CNP were found between the dentate and edentulous patients evaluated with TCHC in relation to sex and age.

Diagnostic Value of American Thyroid Association Guidelines,American College of Radiology Thyroid Imaging Reporting and Data System,and Chinese Thyroid Imaging Reporting and Data System Alone and Combined With BRAFV600E Mutation in Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance / 中国医学科学院学报

Objective To explore the diagnostic efficacy of American Thyroid Association(ATA)guidelines,American College of Radiology Thyroid Imaging Report and Data System(ACR-TIRADS),and Chinese Thyroid Imaging Reporting and Data System(C-TIRADS)alone and combined with BRAFV600E mutation in atypia of undetermined significance/follicular lesion of undetermined significance(AUS/FLUS).Methods A total of 138 patients who underwent ultrasound-guided fine needle aspiration(FNA)in the Chinese PLA General Hospital from January 2020 to May 2023 were selected.The clinicopathological and ultrasound characteristics were retrospectively analyzed for each nodule.Each nodule underwent preoperative BRAFV600E mutation testing and was diagnosed according to the ATA guidelines,ACR-TIRADS,and C-TIRADS.The diagnostic efficacy of ATA guidelines,ACR-TIRADS,and C-TIRADS alone and combined with BRAFV600E mutation was assessed based on the results of histopathological diagnosis.Results The 138 AUS/FLUS thyroid nodules included 45(32.6%)benign ones and 93(67.4%)malignant ones.The patient age(t=1.444,P=0.151),gender(χ2=0.259,P=0.611),and location of nodules(χ2=2.055,P=0.358)had no statistical significance for the differentiation between benign and malignant nodules,while nodule size(Z=2.500,P=0.012),echo(χ2=14.693,P<0.001),composition(χ2=17.075,P<0.001),aspect ratio ≥1(χ2=9.477,P=0.002),and microcalcification(χ2=6.892,P=0.009)were of significance for the differentiation.When applied alone,BRAFV600E mutation showed high specificity(95.56%)and positive predictive value(95.65%).Among the three ultrasound grading systems,ACR-TIRADS had the highest sensitivity(χ2=37.923,P<0.001;χ2=40.462,P<0.001)and accuracy(χ2=81.595,P<0.001;χ2=76.912,P<0.001),while C-TIRADS had the highest specificity(χ2=11.746,P<0.001;χ2=21.235,P<0.001).However,the three systems showed no statistically significant difference in the diagnostic efficiency when applied alone(Z=1.177,P=0.239;Z=0.213,P=0.831;Z=1.016,P=0.310).The combination of BRAFV600E mutation with ACR-TIRADS or C-TIRADS improved the diagnostic efficacy of BRAFV600E mutation in distinguishing the benign and malignant AUS/FLUS nodules(Z=2.107,P=0.035;Z=2.752,P=0.006).The combination of ATA guidelines with BRAFV600E mutation increased the diagnostic accuracy of BRAFV600E mutation(χ2=20.679,P<0.001),while it had no statistically significant difference in distinguishing the benign and malignant AUS/FLUS nodules(Z=1.321,P=0.186).The combination of ATA guidelines,ACR-TIRADS,or C-TIRADS with BRAFV600E mutation improved the diagnostic efficacy of ultrasound grading systems for AUS/FLUS nodules(Z=2.770,P=0.006;Z=2.770,P=0.006;Z=2.890,P=0.004).Specifically,ACR-TIRADS combined with BRAFV600E mutation showed the highest sensitivity(χ2=4.712,P=0.030;χ2=4.712,P=0.030),while C-TIRADS combined with BRAFV600E mutation showed the highest accuracy(χ2=77.627,P<0.001;χ2=85.827,P<0.001).However,there were no statistically significant differences in diagnostic performance between the combinations(Z=1.276,P=0.202;Z=0.808,P=0.419;Z=1.615,P=0.106).Conclusion ATA guidelines,ACR-TIRADS,and C-TIRADS combined with BRAFV600E mutation can improve the diagnostic efficacy of BRAFV600E mutation or ultrasound grading system alone in AUS/FLUS nodules,which can facilitate the further management and treatment of such patients.

Avaliação clínica e epidemiológica de sarcomas: estudo retrospectivo de base de registro hospitalar de câncer do Estado de São Paulo / Clinical and epidemiological evaluation of Sarcomas: a retrospective study based on the hospital cancer registry in the State of São Paulo

Introdução: Os sarcomas são tumores raros e heterogêneos com origem mesenquimal. Atualmente são reconhecidos mais de 80 subtipos histológicos distintos. O tratamento compreende cirurgia, radioterapia e quimioterapia. A taxa de recidiva tumoral após a cirurgia e a sobrevida variam de acordo com o subtipo, graus histológicos e o estádio TNM. Por ser uma neoplasia rara, há inúmeras barreiras para o adequado diagnóstico e tratamento dos sarcomas.Objetivos: avaliar as características sociodemográficas e clínicas de pacientes com sarcomas tratados no estado de São Paulo. Objetivos secundários: Avaliar a frequência de sarcomas de partes moles no estado de São Paulo, as características sociodemográficas e clínicas, avaliar os padrões de tratamento, analisar a sobrevida global dos pacientes, analisar possíveis fatores prognósticos relacionados com a sobrevida. Metodologia: estudo observacional, de coorte retrospectiva, descritivo, de pacientes com diagnóstico de Sarcomas de Partes moles identificados na rede de registros hospitalares de câncer do Estado de São Paulo, Brasil, no período de 2008 a 2018. Foram analisadas variáveis sociodemográficas (sexo, idade, grau de escolaridade, tipo de instituição de tratamento e sistema de saúde), tempo do diagnóstico até o início do tratamento, subtipo histológico, localização do tumor primário, estadiamento TNM e tipo de tratamento empregado (cirurgia, radioterapia, quimioterapia e combinações). Foi realizada uma análise descritiva das variáveis, descrevendo as distribuições de frequência absoluta (n) e relativa (%) para as variáveis qualitativas, e as principais medidas resumo, como a média, desvio padrão, mediana, valores mínimo e máximo para as variáveis quantitativas. Para avaliar a associação entre variáveis qualitativas, foi utilizado o teste qui-quadrado ou o teste exato de Fisher, quando apropriado. A sobrevida global foi estimada pelo método de Kaplan Meier e a comparação entre as curvas de sobrevida foi feita pelo teste de log-rank. O modelo de regressão de Cox foi empregado para identificar variáveis relacionadas com o prognóstico. Adotou-se valor de significância de p de 0,05. Resultados foram incluídos na análise 3626 pacientes. A idade média foi de 51 anos (18-99 anos). Houve um discreto predomínio do sexo feminino (50,2%). A minoria tinha nível de ensino superior (10%), o tratamento ocorreu no SUS em 63,4% e na capital em 54,7% e 58,2% iniciaram o tratamento em menos de 60 dias. Houve predomínio de lipossarcoma e leiomiossarcoma (17,9% e 15,0%, respectivamente) e 45,8% tinham tumor nas extremidades e 31,5% no retroperitôneo. De acordo com o TNM, houve 6,4% estádio IA, 11,5% IB, 3,9% IIA, 6,1% IIB, 22% III, 20,8% IV, 11,3% X e 18,0% Y. Cirurgia, radioterapia e quimioterapia foram empregadas em 70,1%, 32,2% e 43,9%, respectivamente. Os pacientes tratados no SUS tiveram maior tempo para início do tratamento (76 x 58 dias, p <0,001) e foram tratados com menos cirurgia e radioterapia (68,7%x77,2%, p <0,001 e 31,8% x 37,2%, p 0,012, respectivamente). A sobrevida global mediana foi de 49 meses e a sobrevida global em 1, 2 e 5 anos foi de 76%, 63% e 46%, respectivamente. Na análise multivariada de Cox idade, local de tratamento, nível de escolaridade e sexo foram variáveis independentes para sobrevida global. Conclusão: Identificamos que houve atraso no início do tratamento após o diagnóstico para uma grande parcela dos pacientes. Além disso, encontramos discrepância significativa no tempo para início do tratamento de acordo com o sistema atendimento. Os pacientes do sistema público de saúde tiveram maior tempo para iniciar o tratamento. Nossos achados apontam para a existência de disparidades no sistema de saúde e reforçam a necessidade de mais estudos para entender melhor as barreiras enfrentadas pelos pacientes com diagnóstico de sarcomas.

Introduction: Sarcomas are rare and heterogeneous tumors with mesenchymal origin. Treatment includes surgery, radiotherapy, and chemotherapy. The tumor recurrence rate after surgery and survival varies according to the histological subtype. More than 80 distinct histological subtypes are currently recognized. Because it is a rare neoplasm, there are numerous barriers to proper diagnosis and treatment. Objectives: evaluation of sociodemographic and clinical characteristics of patients with sarcomas treated in the state of São Paulo. Secondary objectives: To evaluate the frequency of soft tissue sarcomas in the state of São Paulo, socio-demographic and clinical characteristics, evaluate treatment standards, analyze the overall survival of patients, and analyze possible prognostic factors related to survival. Methodology: observational, cohort, descriptive, retrospective study of patients diagnosed with soft tissue sarcomas identified in the network of hospital cancer registries in the state of São Paulo, Brazil, from 2008 to 2018. Socio demographic variables were analyzed (gender, age, educational level, type of treatment institution, health system), time from diagnosis to start of treatment, histological subtype, primary tumor location, tumor size, TNM staging, type of treatment employed (surgery, radiotherapy, chemotherapy and combinations). Statistical analysis: a descriptive analysis of the variables was performed, describing the absolute (n) and relative (%) frequency distributions for the qualitative variables, and the main summary measures, such as mean, standard deviation, median, minimum and maximum values were calculated. To assess the association between qualitative variables, the chi-square test or Fisher's exact test were used when appropriate. Overall survival was estimated using the Kaplan-Meier method and a comparison between survival curves was performed using the logrank test. A significance value of p value of 0.05 was adopted. Results: A total of 3626 patients were included in the analysis. The median age was 51 years (range 18 to 99 years). There was a slight predominance of females (50.2%). The minority had a higher education level (10%); the treatment took place in the public health care system (SUS) in 63.4% and in the capital in 54.7%, and 58.2% started treatment in less than 60 days. There was a predominance of liposarcoma and leiomyosarcoma (17,9.4% and 15.0%, respectively) and 45.8% had tumor in the extremities and 31.5% in the retroperitoneum. According to the TNM, there were 6.4% stage IA, 11.5% IB, 3.9% IIA, 6.1% IIB, 22% III, 20.8% IV, 11.3% X and 18.0% Y. Surgery, radiotherapy and chemotherapy were used in 70.1%, 32.2% and 43.9%, respectively. Patients treated at SUS had a longer time to start treatment (76 x 58 days, p <0.001) and were treated with less surgery and radiotherapy (68.7% x 77.2%, p <0.001 and 31.8% x 37.2%, p 0.012, respectively). The median overall survival was 49 months and the overall survival at 1, 2 and 5 years was 76%, 63% and 46%, respectively. In Cox's multivariate analysis, age, sex, educational level and local of treatment were independent variables for overall survival. Conclusion: We identified that there was a delay in starting treatment after diagnosis for a large proportion of patients. Furthermore, we found a significant discrepancy in the time to start treatment according to the care system. Patients in the public health system had longer time to start treatment. Our findings point to the existence of disparities in the healthcare system and reinforce the need for more studies to better understand the barriers faced by patients diagnosed with sarcomas.

Medición radiológica del extremo proximal del fémur / Radiological measurement of the femoral proximal end

El objetivo de este trabajo es determinar las mediciones radiológicas del extremo proximal del fémur en pacientes adultos cuyos casos fueron presentados en las discusiones clínico-radiológicas del servicio de Traumatología y Ortopedia del Hospital Central de San Cristóbal entre 2015 y 2021. Se realizó un estudio prospectivo, descriptivo, transversal, que incluyó los estudios radiológicos de cadera sana en proyección anteroposterior de pelvis centrada en pubis con rotación interna de 15 %, de 126 pacientes entre 20 y 95 años. Se midieron: ángulo cervicodiafisario, lateralización femoral, longitud y ancho del cuello femoral y diámetro de la circunferencia cefálica, mediante el sotfware MicroDicom DICOM 4.0.0. La media de ángulo cervicodiafisario fue 130,8 ± 4,5 grados, en 57 individuos (45,2 %) estuvo entre 127,4 y 133,3 grados (p = 0,001); la circunferencia cefálica media fue 42,0 ± 2,4 mm, en 60 personas (47,6 %) estuvo entre 40,2 y 45,7 mm (p = 0,001); la longitud cervical media fue 78,6 ± 16,4 mm, en 54 individuos (42,9 %) estuvo entre 69,4 y 92 mm (p = 0,001); el ancho cervical medio fue 75,9 ± 12,1 mm, en 64 casos, (50,8 %) estuvo entre 62,9 y 78,7 mm (p = 0,001). En 60 individuos (47,6 %) la lateralización del fémur estuvo entre 92,6 - 117,7 mm. Las medidas son independientes del sexo; a medida que aumenta la edad, el ángulo cervicodiafisario es menor (p= 0,021). Se realizaron tablas percentiladas de las medidas radiológicas del extremo proximal del fémur, según edad y sexo, que pueden servir de referencia en pacientes futuros(AU)

The objective of this work is to determine the radiological measurements of the proximal end of the femur in adult patients whose cases were presented in the clinical-radiological discussions of the Traumatology and Orthopedics service of the Central Hospital of San Cristóbal between 2015 and 2021. A prospective study was carried out, descriptive, crosssectional, which included radiological studies of a healthy hip in anteroposterior projection of the pelvis centered on the pubis with internal rotation of 15%, of 126 patients between 20 and 95 years of age. The following were measured: cervicodiaphyseal angle, femoral lateralization, length and width of the femoral neck, and diameter of the head circumference, using the MicroDicom DICOM 4.0.0 software. The mean neck-diaphyseal angle was 130.8 ± 4.5 degrees, in 57 individuals (45.2%) it was between 127.4 and 133.3 degrees (p = 0.001); the mean head circumference was 42.0 ± 2.4 mm, in 60 people (47.6%) it was between 40.2 and 45.7 mm (p = 0.001); the mean cervical length was 78.6 ± 16.4 mm, in 54 individuals (42.9 %) it was between 69.4 and 92 mm (p = 0.001); the mean cervical width was 75.9 ± 12.1 mm, in 64 cases (50.8%) it was between 62.9 and 78.7 mm (p= 0.001). In 60 individuals (47.6%), the lateralization of the femur was between 92.6 - 117.7 mm. The measurements are independent of sex; as age increases, the cervical shaft angle is less (p= 0.021). Percentage tables of the radiological measurements of the proximal end of the femur were made, according to age and sex, which can serve as a reference in future patients(AU)

Calidad radiográfica obtenida por estudiantes de Odontología mediante la técnica de bisectriz / Radiographic quality obtained by dental students using the bisecting angle technique

Objetivo: Evaluar la calidad radiográfica mediante técnica de la bisectriz ejecutada por estudiantes de Odontología de tercer año. Material y Método: Estudio observacional descriptivo. Se evaluaron 220 radiografías ejecutadas por 55 estudiantes de Odontología de tercer año. La calidad radiográfica fue evaluada por dos investigadores, mediante una pauta creada con cuatro parámetros: posición de la película, angulación horizontal, angulación vertical y rayos X centrado. Fue comparada la calidad según sector radiográfico, anterior y posterior. Se realizó estadística descriptiva y prueba de chi-2 para establecer diferencias entre calidad y sector radiográfico, con un valor de significancia estadística de p0.05. Conclusión: Las radiografías periapicales tomadas mediante técnica de la bisectriz por estudiantes de Odontología de tercer año, son mayoritariamente de calidad inaceptable, sin diferencias significativas entre sectores.

Objective: To evaluate radiographic quality using the bisecting angle technique performed by third-year dental students. Material and Method: Descriptive observational study. 220 radiographs were evaluated, performed by 55 third-year dental students. Radiographic quality was evaluated by two researchers, using a guideline created with four parameters: film position, horizontal angulation, vertical angulation and centered X-ray (conecut). The quality was compared according to the radiographic sector, anterior and posterior. Descriptive statistics and chi-2 test were applied to establish differences between radiographic sector and radiographic quality, setting a value of statistical significance of p 0.005. Conclusions: The periapical radiographs taken by third-year dental students using the bisecting angle technique is mostly of unacceptable quality, with no significant differences between sectors.

Guidelines for Diagnosis and Treatment of Pancreatic Cystic Neoplasms Based on Radiology / 中国医学科学院学报

As the detection rate of pancreatic cystic neoplasms (PCN) increases,recommendations or guidelines for the diagnosis and treatment of PCN have been released from professional organizations.From the perspective of radiology,we compared seven guidelines in terms of general introduction,preoperative monitoring methods and strategies,stratification of risk factors,surgical indications,and postoperative follow-ups,aiming to provide references for the evaluation of images and the formulation of individualized approach for the treatment of PCN.

CO-RADS: aplicación móvil para la estandarización del informe radiológico en el contexto de la COVID 19 / CO-RADS: Mobile Application for Standardization of the Radiological Report in the Context of COVID 19

El nuevo coronavirus denominado SARS-COV2 causa diversas manifestaciones clínicas englobadas bajo el término COVID-19. El sistema de informe y datos conocidos por sus siglas en inglés como RADS, determinadas a partir del consenso de expertos producido por un grupo de trabajo multidisciplinario con el objetivo de mejorar la comunicación de los resultados, establece un enfoque estándar para la notificación de manifestaciones imagenológicas. El presente trabajo presenta el prototipo de aplicación CO-RADS que propone una herramienta digital sobre la base de una revisión actualizada del papel y la idoneidad de los estudios de imagenología para el diagnóstico y seguimiento de pacientes con sospecha o infección conocida de COVID-19, proporcionando terminología estandarizada de imágenes para lograr comunicar los resultados al médico de asistencia de manera clara y consistente. CO-RADS es una aplicación gratuita que se encuentra disponible en: htttps://www.aplikis.cu/es/application/cu.sld.hlucia.corads(AU)

The new coronavirus called SARS-COV2 causes various clinical manifestations encompassed under the term COVID-19. The data and reporting system known by its acronym in English as RADS, establishes a standard approach for the notification of imaging manifestations with the aim of improving the communication of results; was determined from the consensus of experts produced by a multidisciplinary working group. This paper presents the CO-RADS application prototype that proposes a digital tool based on an updated review of the role and suitability of imaging studies for the diagnosis and follow-up of patients with suspected or known COVID-19 infection, providing standardized imaging terminology to achieve clear and consistent communication of results to the attending physician. CO-RADS is a free application that is available at: htttps://www.aplikis.cu/es/application/cu.sld.hlucia.corads(AU)

Rastreio radiológico para tuberculose em uma penitenciária do sul do Brasil / Radiological screening for tuberculosis in a prison in the south of Brazil

Introdução: Conhecer o perfil da população privada de liberdade da Penitenciária Modulada de Osório (PMO), do ponto de vista radiológico e estimar a prevalência da tuberculose ativa no presídio.Métodos: Foi realizada análise retrospectiva de 677 radiografias de tórax obtidas para rastreio de tuberculose e de dados da ficha de atendimento do setor de Radiologia no período de julho a outubro de 2019.Resultados: Foram detectadas 150 radiografias alteradas, o que representa 22% dos 677 exames. Dos 150 exames alterados, 109 (16% do total e 72% dos alterados) apresentavam lesões com características de doença granulomatosa. Dos 677 pacientes, 11,5% referiram tratamento atual ou prévio para tuberculose e estes representam 38% dos casos com radiografias alteradas. Foram detectados 50 pacientes sem história prévia de tuberculose com lesões de aspecto muito provavelmente devido a tuberculose com características de doença ativa (7,3% do total), os quais foram encaminhados para investigação como casos novos. Em relação ao questionário aplicado, não foi observada diferença significativa entre os pacientes que referiam ou negavam tosse entre os com exames normais e alterados.Conclusões: Os indivíduos privados de liberdade apresentaram alta prevalência de alterações radiológicas com aspecto sugestivo de doença granulomatosa. Estes achados permitem inferir que na Penitenciária Modulada de Osório há elevada prevalência de tuberculose, provavelmente em níveis semelhantes a outras casas prisionais do Brasil.

Introduction: To determine the radiologic profile of 'the prisoners at Osório Modular Prison and estimate the prevalence of active tuberculosis in the institution.Methods: We retrospectively analyzed 677 chest radiographs obtained for tuberculosis screening and data from the medical records of prisoners seen at the Radiology Department from July to October 2019.Results: Of 677 radiographs, 150 (22%) showed abnormalities. Of these, 109 (16% of total or 72% of abnormal radiographs) showed lesions characteristic of granulomatous disease. Of all 677 patients, 11.5% reported current or previous treatment of tuberculosis, accounting for 38% of all abnormal radiographs. Fifty patients with no previous history of tuberculosis had lesions that were most likely due to active tuberculosis (7.3% of total), and were referred for further investigation as new cases. The responses to the questionnaire revealed no significant difference between patients who reported or denied coughing when comparing those with normal vs abnormal radiographs.Conclusions: Individuals deprived of liberty had a high prevalence of radiologic abnormalities suggestive of granulomatous disease. These findings allow us to infer that there is a high prevalence of tuberculosis at Osório Modular Prison, probably at levels comparable to those of other prison facilities in Brazil.

Giant pulmonary artery aneurysms / Aneurismas gigantes de arteria pulmonar

The accompanying images demonstrate giant pulmonary artery aneurysms in a patient with idiopathic pulmonary arterial hypertension (Image 1). In addition to the main pulmonary artery, both the left and right pulmonary arteries are aneurysmal and are compressing the lung parenchyma (Image 2).

Las imágenes adjuntas muestran aneurismas gigantes de la arteria pulmonar en un paciente con hipertensión arterial pulmonar idiopática (Imagen 1). Además de la arteria pulmonar principal, tanto la arteria pulmonar izquierda como la derecha son aneurismáticas y están comprimiendo el parénquima pulmonar (Imagen 2).

Inteligencia artificial: una herramienta en la imagenología para los pacientes positivos a la COVID-19 / Artificial intelligence: an imaging tool for COVID-19 positive patients

RESUMEN Introducción: la enfermedad por SARS-Cov-2 refuerza la importancia del uso de las nuevas tecnologías de la información y las comunicaciones en función del desarrollo e implementación de sistemas de inteligencia artificial que favorecen el diagnóstico. Objetivo: describir la posibilidad del uso de la inteligencia artificial como una herramienta en la imagenología para los pacientes positivos a la COVID-19. Métodos: se realizó una revisión de fuentes bibliográficas en Infomed, SciELO, PubMed y Google Académico, comprendidas en los años 2015 al 2020 con el uso de palabras claves: coronavirus, COVID-19, neumonía, radiografía e inteligencia artificial. Se seleccionaron 28 documentos por su pertinencia en el estudio. Desarrollo: la creación de sistemas de inteligencia artificial que ayuden al diagnóstico médico requiere un enfoque interprofesional de la ciencia y constituye una de las líneas de trabajo en Cuba durante la pandemia. Una condición indispensable para la introducción de la inteligencia artificial en el diagnóstico radiológico es la capacitación que deben recibir los médicos para interactuar con ella, a través de un proceso formativo que incluya una evaluación y explicación de la calidad de los datos asociada tanto al aprendizaje como a las nuevas predicciones. Conclusiones: la utilización de inteligencia artificial mejorará el rendimiento del radiólogo para distinguir la COVID-19; la integración de estas tecnologías en el flujo de trabajo clínico de rutina puede ayudar a los radiólogos a diagnosticar con precisión.

ABSTRACT Introduction: SARS-Cov-2 disease reinforces the importance of the use of new information and communication technologies based on the development and implementation of artificial intelligence systems that favor diagnosis. Objective: to describe the possibility of using artificial intelligence as a tool in imaging for COVID-19 positive patients. Methods: a review of bibliographic sources was carried out in Infomed, SciELO, PubMed and Google Scholar, from 2015 to 2020 with the use of keywords: coronavirus, COVID-19, pneumonia, radiography and artificial intelligence. 28 documents were selected for their relevance in the study. Development: the creation of artificial intelligence systems that help medical diagnosis requires an interprofessional approach to science and constitutes one of the lines of work in Cuba during the pandemic. An essential condition for the introduction of artificial intelligence in radiological diagnosis is the training that doctors must receive to interact with it, through a training process that includes an evaluation and explanation of the quality of the data associated with both learning and to new predictions. Conclusions: the use of artificial intelligence will improve the radiologist's performance to distinguish COVID-19; integrating these technologies into routine clinical workflow can help radiologists diagnose accurately.

Analysis of Intraoperative Exposure to X-rays and Surgical Time in Different Techniques for Fixation of Transtrochanteric Fractures of the Femur / Análise da exposição intraoperatória ao raio X e do tempo cirúrgico em diferentes técnicas de fixação das fraturas transtrocanterianas do fêmur*

Abstract Objective The present study aimed to evaluate and compare the total surgical procedure time and intraoperative X-ray exposure during different techniques for fixation of transtrochanteric fractures of the femur in elderly patients, using extramedullary and intramedullary methods based on cephalic traction screws. Methods The Orthopedics and Traumatology Service from our hospital evaluated 107 patients with transtrochanteric fractures, including 34 males and 73 females, with age ranging from 61 to 101 years old. Fracture fixation was performed with a dynamic hip system (DHS) in 21 patients, a standard proximal femoral nail (PFN) in 55 subjects, and a standard gamma nail in 31 patients. All procedures were performed by the same surgeon and his team of nursing assistants, along with the same radiology technician using the same image intensifier. Total surgery time (in minutes) and X-ray emission (in centigrays [cGy]) were evaluated. Results Transtrochanteric fracture fixation with PFN provides a significantly shorter surgical time (p = 0.013) in comparison to the 2 other techniques. Intraoperative exposure to X-rays was significantly lower when using DHS (p = 0.015) as a fixation method when compared with gamma nail and PFN. Conclusion Although PFN resulted in the shortest surgical time, DHS was associated with the lowest X-ray exposure levels within the studied sample.

Resumo Objetivo Avaliar e comparar o tempo total do procedimento cirúrgico e a exposição ao raio X no intraoperatório em diferentes técnicas de fixação das fraturas transtrocanterianas do fêmur em pacientes idosos, utilizando técnicas extramedulares e intramedulares baseadas em parafuso de tração cefálico. Métodos Foram avaliados no serviço de ortopedia e traumatologia do nosso hospital 107 pacientes com fraturas transtrocanterianas, sendo 34 do sexo masculino e 73 do sexo feminino, com idade mínima de 61 anos e máxima de 101 anos. As fraturas fixadas, utilizando a técnica com dynamic hip system (DHS, na sigla em inglês) somaram 21 pacientes; em 55 pacientes, foi utilizado o proximal femur nail (PFN, na sigla em inglês) standard; e em 31 idosos, foi optado pelo uso do gama nail standard. Todos os procedimentos foram realizados pelo mesmo cirurgião acompanhado de sua equipe de auxiliares de enfermagem, assim como pelo mesmo técnico de radiologia manuseando o mesmo intensificador de imagens. Foram avaliados o tempo total da cirurgia (em minutos) e a emissão de raios X medida em centigrays. Resultados A fixação das fraturas transtrocanterianas com PFN proporciona um menor tempo cirúrgico com uma diferença estatística significativa (p =0,013), quando comparada com as demais técnicas utilizadas entre os grupos envolvidos. Foi observada, também, uma menor exposição intraoperatória aos raios X (p =0,015), a qual foi estatisticamente relevante quando utilizado o DHS como método de fixação comparado com o gama nail e o PFN. Conclusão Apesar do PFN ter o menor tempo de cirurgia, a técnica do DHS se mostrou com menores níveis de exposição dentro da amostra estudada.

Implementación de telerradiología en neurotrauma en áreas de difícil acceso-revisión sistemática / Implementation of teleradiology in neurotrauma in areas of difficult access - systematic review

ABSTRACT: Introduction: According to the world health organization, injuries represent more than 20% of health problems in the world. Head trauma and the absence of neurosurgery and radiology services in less populated areas make it difficult to assess and manage patients with brain injury. Objective: To describe the clinical findings and benefits derived from the implementation of teleradiology in neurotrauma in areas of difficult geographic access. Materials and methods: A systematic search was carried out in Pubmed, Scopus, Ebsco host, Sciencedirect, and Embase, with the thesauri "Teleradiology" and "Craniocerebral Trauma". Results: The decision to intervene in a patient with brain trauma and the period of time until surgery are essential for the clinical outcome. Those centers that use teleradiology require transfers to specialized hospitals, for which portable technological devices contribute to the response time of neurosurgery care. Conclusion: Teleradiology has a positive impact on patients with traumatic brain injury in geographical areas of difficult access, facilitating communication with specialists; providing timely care and optimizing transfers to high complexity centers.

RESUMEN: Introducción: Según la organización mundial de la saludlos traumatismos representan más del 20% de los pro-blemas en salud en el mundo. El trauma craneoencefálico y la ausencia de servicios de neurocirugía y radiología en zonas menos pobladas dificultan la valoración y manejo de pacientes con lesión cerebral. Objetivo: Describir los hallazgos clínicos y beneficios derivados de la implementación de la telerradiología en neurotrauma en áreas de difícil acceso geográfico. Materiales y métodos: Se realizó una búsqueda sistemática en Pubmed, Scopus, Ebsco host, Sciencedirect, y Embase, con los tesauros "Teleradiology" y "Craniocerebral Trauma". Resultados: La decisi-ón de intervenir a un paciente con traumatismo cerebral y el periodo de tiempo hasta la cirugía son fundamentales para el desenlace clínico. Aquellos centros que usan la telerradiología, precisan los traslados a los hospitales espe-cializados, por lo cual los dispositivos tecnológicos portátiles contribuyen en el tiempo de respuesta de la atención en neurocirugía. Conclusión: La telerradiología impacta positivamente en pacientes con trauma craneoencefálico en zonas geográficas de difícil acceso, facilitando la comunicación con especialistas; brindando atención oportuna y optimizando los traslados a centros de alta complejidad. (AU)

Adult-onset non-5q proximal spinal muscular atrophy: a comprehensive review / Atrofia muscular espinhal não-5q proximal de início no adulto: uma revisão abrangente

Abstract Background: Adult-onset spinal muscular atrophy (SMA) represents an expanding group of inherited neurodegenerative disorders in clinical practice. Objective: This review aims to synthesize the main clinical, genetic, radiological, biochemical, and neurophysiological aspects related to the classical and recently described forms of proximal SMA. Methods: The authors performed a non-systematic critical review summarizing adult-onset proximal SMA presentations. Results: Previously limited to cases of SMN1-related SMA type 4 (adult form), this group has now more than 15 different clinical conditions that have in common the symmetrical and progressive compromise of lower motor neurons starting in adulthood or elderly stage. New clinical and genetic subtypes of adult-onset proximal SMA have been recognized and are currently target of wide neuroradiological, pathological, and genetic studies. Conclusions: This new complex group of rare disorders typically present with lower motor neuron disease in association with other neurological or systemic signs of impairment, which are relatively specific and typical for each genetic subtype.

RESUMO Antecedentes: Atrofia muscular espinhal (AME) de início no adulto representa um grupo de doenças neurodegenerativas hereditárias em expansão na prática clínica. Objetivo: Este artigo de revisão sintetiza os principais aspectos clínicos, genéticos, radiológicos, bioquímicos e neurofisiológicos relacionados às formas clássicas e recentemente descritas de AME proximal do adulto. Métodos: Os autores realizaram uma revisão crítica não sistemática descrevendo as principais apresentações de AME proximal de início no adulto. Resultados: Previamente restrito às apresentações de AME tipo 4 associada ao gene SMN1, este grupo atualmente envolve mais de 15 diferentes condições clínicas que compartilham entre si a presença de comprometimento progressivo e simétrico do neurônio motor inferior se iniciando no adulto ou no idoso. Novos subtipos clínicos e genéticos de AME proximal de início no adulto foram reconhecidas e são alvos atuais de estudos direcionados a aspectos neurorradiológicos, patológicos e genéticos. Conclusões: Este novo grupo complexo de doenças raras tipicamente se apresenta com doença do neurônio motor inferior em associação com outros sinais de comprometimento neurológico ou sistêmico, os quais apresentam padrões relativamente específicos para cada subtipo genético.

Prevalence of Errors and Number of Retakes in Panoramic Radiography: influence of Professional Training and Patient Characteristics / Prevalencia de Errores y Número de Repeticiones en Radiografía Panorámica: influencia de la Formación Profesional y las Características de los Pacientes

Panoramic radiography has clinical importance in several dental specialties. The objective of this study was to evaluate the influence of professionals' experience and patient characteristics (age group and dental absence) in the prevalence of errors and the number of retakes in the panoramic radiography.771 panoramic radiographs were evaluated and classified according to the group of patients (children, dentulous adults, total edentulous adults, and anterior edentulous adults) and professionals who performed the technique (novice and experienced). The association between frequency and type of error, group of patients, professionals' experience, and number of retakes was performed by the Chi-square and Fisher's exact test (a=0.05). There was no significant association between the frequency of errors or retakes of the radiograph s and the professionals' experience or patients' characteristics (p<0.05). The errors "turned head" and "tongue not against the palate," "chin tipped low", "chin not resting on the support," "patient movement during exposure," and "lead apron artifact" showed significantly higher frequency of retake (p<0.05). The most frequent type of error was due to the failure to position the tongue against the palate for all patients and both groups of professionals. The frequency of errors in the panoramic radiography occurs regardless of the professionals' experience, and age and dental absence of the patients. Error occurs mainly due to the lack of patient collaboration, and the examination is rarely repeated by the professionals.

La radiografía panorámica es de importancia clínica en varias especialidades dentales. El objetivo de este estudio fue evaluar la experiencia de los profesionales y las características de los pacientes (grupo etario y ausencia dentaria) en la prevalencia de errores y el número de repeticiones en la radiografía panorámica.771 radiografías panorámicas fueron evaluadas y clasificadas según la grupo de pacientes (niños, adultos desdentados, adultos desdentados totales y adultos desdentados anteriores) y profesionales que realizaron la técnica (novatos y experimentados). La asociación entre frecuencia y tipo de error, grupo de pacientes, experiencia de los profesionales y número de repeticiones se realizó mediante la prueba de Chicuadrado y exacta de Fisher (a = 0,05). No hubo asociación significativa entre la frecuencia de errores o repetición de las radiografías y la experiencia de los profesionales o las características de los pacientes (p <0,05). Los errores "cabeza girada" y "lengua no contra el paladar", "mentón inclinado hacia abajo", "mentón no apoyado en el soporte", "movimiento del paciente durante la exposición" y "artefacto del delantal de plomo" mostraron una frecuencia de repetición significativamente mayor (p < 0,05). El error más frecuente se debió a la falta de posicionamiento de la lengua contra el paladar para todos los pacientes y en ambos grupos de profesionales. La frecuencia de errores en la radiografía panorámica ocurre independientemente de la experiencia de los profesionales, edad y ausencia dentaria del pacientes. El error se produce principalmente por la falta de colaboración del paciente, y los profesionales rara vez repiten el examen.

Centenario de Médica, el legado mayor del Dr. Mario E. Dihigo / The centenary of Medica, the biggest legacy of Dr. Mario E. Dihigo

RESUMEN Introducción: el Dr. Mario E. Dihigo Llanos, junto a un grupo de colegas emprendedores, fundó en Matanzas, en 1921, la revista Médica (devenida Revista Médica Electrónica en 1997). Objetivos: resaltar el centenario de la publicación y contribuir a la preservación de la memoria del eximio pedagogo. Materiales y métodos: fueron utilizados métodos de la investigación histórica, como el analítico-sintético y el deductivo-inductivo, así como los submétodos cronológico y geográfico. Se realizaron entrevistas y se revisó el legado documental del Dr. Dihigo. La información fue triangulada con las fuentes referenciadas y con otras bibliografías y documentos consultados. Resultados: se resaltaron algunos de los aspectos más significativos relacionados con la vida y la obra del Dr. Dihigo, y se realizó una caracterización de las primeras etapas de la revista, donde se abordan su significación histórica y científica. Conclusiones: sus aportes en Medicina y Pedagogía, así como sus esfuerzos por establecer la revista Médica, son los mayores legados de Dihigo (AU).

ABSTRACT Introduction: Dr. Mario E. Dihigo Llanos, and a group of colleagues-enterprisers, founded the journal Medica (renamed Revista Medica Electronica in 1997) in Matanzas, in 1921. Objectives: to highlight the centenary of the journal and to contribute to keep the memory of the prominent pedagogue up. Materials and methods: methods of the historical research were used like the analytic-synthetic and the deductive-inductive ones, and also the chronological and geographic sub-methods. Interviews were made and the documental legacy of Dr. Mario Dihigo was reviewed. The information was compared with the referenced sources and the other referred bibliography and documents. Results: some of the most significant features of Dr. Dihigo's life and work were emphasized. A characterization of the first stages of the journal was carried out, approaching its historical and scientific significance. Conclusions: the main Dihigo's legacies were his contributions to Medicine and Pedagogy, and his efforts for founding the journal Medica (AU).

Tumor desmoide abdominal gigante en puerperio: caso clínico y revisión de la literatura / Giant abdominal desmoid tumor during the puerperium: Case report and review of literature

Introducción. Los tumores desmoides o fibromatosis agresiva corresponden a neoplasias mesenquimales poco frecuentes. Son tumores localmente agresivos que ocurren especialmente en jóvenes, no desarrollan metástasis a distancia, pero se asocian con invasión locorregional y alta tasa de recurrencia después de la resección. Su etiología es desconocida, pero se ha asociado al síndrome de Gardner, trauma, embarazo, estados hiperestrogénicos y puerperio. El objetivo de este artículo fue hacer una revisión sobre el tema a propósito de un caso clínico. Caso clínico. Se presenta el caso de una paciente puérpera con progresivo y rápido aumento del volumen abdominal. Se realizó una tomografía computarizada de abdomen y pelvis que confirmó la presencia de una masa intraperitoneal bien definida. La paciente fue operada con escisión de la masa y confirmación histológica de tumor desmoide a partir de la muestra de patología. Discusión. Los tumores desmoides tienen una incidencia de 2 a 4 casos por millón de habitantes por año, con leve predominio en el sexo femenino y representan menos del 3 % de los tumores de partes blandas. Aunque el tumor se puede ubicar a nivel intraabdominal o en la pared, la ubicación más común es en las extremidades. Conclusiones. La sospecha y detección del tumor desmoide es fundamental, así como su adecuado estudio, para determinar el tratamiento quirúrgico como fue realizado en este caso

Introduction. Desmoid tumors or aggressive fibromatosis correspond to rare mesenchymal neoplasms. They are locally aggressive tumors that occur especially in young people, they do not develop distant metastases, but are associated with locoregional invasion and a high recurrence rate after resection. Its etiology is unknown, but it has been associated with Gardner syndrome, trauma, pregnancy, hyperestrogenic states, and puerperium. The objective of this article was to review the topic based on a clinical case. Clinical case. The case of a puerperal patient with progressive and rapid increase in abdominal volume is presented. An abdominal and pelvic CT scan was performed, which confirmed the presence of a well-defined intraperitoneal mass. The patient underwent surgery with excision of the mass and histological confirmation of a desmoid tumor from the pathology sample. Discussion. Desmoid tumors have an incidence of 2 to 4 cases per million inhabitants per year, with a slight predominance in females, and represent less than 3% of soft tissue tumors. Although the tumor can be located intra-abdominal or in the wall, the most common location is in the extremities. Conclusions. The suspicion and detection of the desmoid tumor is essential, as well as its adequate study to determine the surgical treatment as it was done in this case