Efficacy and safety of intra-vesical B.C.G in superficial bladder tumor after TURGB

To determine the effectiveness, safety and side effects of intra-vesicle B.C.G immuno-therapy in superficial bladder tumor after TURGB. Observational study / Quasi-experimental. Bolan Medical College Teaching Hospital Quetta, from August, 2004 to July, 2008. Patients age ranges from 40 to 75 years.21 males and 4 females, with proven superficial bladder tumor [Ta-Tl]were included after TURGB in this study. These 25 patients underwent intra-vesicle immunotherapy [BCG.].These patients were followed up for two years and extent of improvement in presenting symptoms, recurrence of tumor, side effects and complications were noted. Out of 25 patients 23 patients [92%] received BCG immunotherapy after TURGB. Out of these 23 Patients 15 patient [65.2%] showed complete response and 6 patients [26.08%] showed partial response while remaining 2 patients [8.69%] had constant progression in disease and underwent cystectomy. It was concluded that B.C.G immunotherapy is very effective and save patients from recurrence and cystectomy

Incidence of acute pyogenic meningitis in infants and children

118 cases of acute pyogenic meningitis were admitted in the department of Paediatrics Liaquat Medical College, Hospitals Jamshoro/ Hyderabad in one year period with prevalence of 1.57% of the total admissions. After selecting the cases on clinical ground were proceeded further to confirm the diagnosis by cerebrospinal fluid cytochemical analysis, gram staining, culture and sensitivity and detection of the antigen of micro-organism by latex agglutination test