Management of Prolapse Intervertebral Disc by Lumbar Discectomy by Interlaminar Fenestration – A Review of 30 Patients

Background: We are presenting 30 patients who had disc prolapse and surgically treated by interlaminar fenestration and disc excision. Methods: All of them had pain and sciatica for a period of three months prior to surgery. Initially all the patients were treated by conservative measures which failed in the cases which were taken up for the surgery. Results: The diagnosis in all the cases was made on Magnetic Resonance Imaging (MRI), additional computed tomography (CT) scan was done in the cases presenting with sciatica and claudication or suspected LCS. We encountered no difficulty by this approach for the localization of the disc and decompression of the nerve root. Conclusion: This method is a safe, effective and reliable method for treating patients of prolapse intervertebral disc (PIVD).

Management of Traumatic Posterior Dislocation of Hip with Fracture Head of Femur

Traumatic dislocation of hip is a rare injury that occurs due to high energy trauma. Fracture head of femur associated with dislocation of hip occurs is even rarer. Some surgeons recommend conservative treatment, while others recommend surgery. The purpose of this study was to evaluate the method of treatment and outcomes of femoral head fractures. Methods: This study was conducted between 2006-2018 & included 4 patients who presented to the department and were diagnosed with posterior dislocation of hip with fracture of head of femur with a minimum followup of 12 months. Results: All the four cases that presented to the hospital were managed by closed reduction of the hip on the same day & were managed surgically the very next day. Three of four patients presented with clinically & radiologically excellent results on followup. Conclusion: Traumatic dislocation of hip with fractures of the femoral head are rare. Patients can be surgically managed by either excision of fragments or fixation using headless screws. Avascular necrosis and post traumatic degenerative disease of the hip occur but are relatively uncommon

Studies on diagnostic potential of secretory antigens of Mycobacterium bovis.

Culture filtrate proteins (CFPs) of M. bovis were produced by culturing the organism for a period of 3 weeks. These CFPs elicited a good delayed hypersensitivity (DTH) reaction in cattle and guinea pig. However, CFPs showed least cross-reactivity when tested in guinea pigs sensitized with M. bovis BCG and M. phlei. CFPs were found to be well recognized by T-cells of single intradermal test (SIDT) positive cattle and were also sero-reactive. Lymphocyte transformation assay revealed the culture filtrate antigens as major T-cell antigens. CFPs induced a good interferon gamma release as compared to conventional antigen, PPD, thereby highlighting their diagnostic capabilities.

Isolation of etiological agent of hydropericardium syndrome in chicken embryo liver cell culture and its serological characterization.

The virus causing hydropericardium syndrome was isolated in chicken embryo liver (CEL) cell culture from livers obtained from naturally infected broilers. The cytopathic effects characterized by rounding and degeneration of cells were visible 36 hr post infection in first passage. At 4th passage level, the infectivity titre was 5.24 log10 TCID50/ml. In May-Grunwald and Giemsa stained cells, basophilic intranuclear inclusions ('bird eye' inclusion), typical of aviadenovirus infection, were observed. The specificity of inclusion was confirmed by indirect immunofluorescence. Various serological tests, such as agar gel precipitation test, counter immuno electrophoresis, micro serum neutralization test and enzyme linked immunosorbent assay were also standardized to confirm the isolation of etiological agent of hydropericardium syndrome in CEL cell culture and to diagnose the disease in poultry.