Subcorneal Milia-Like Idiopathic Calcinosis Cutis: A Rare Presentation

No abstract available.

Cutaneous Metastasis of Hepatocellular Carcinoma Following Skin Injury after Transcatheter Arterial Chemoembolization

No abstract available.

Cutaneous Metastasis of Hepatocellular Carcinoma Following Skin Injury after Transcatheter Arterial Chemoembolization

No abstract available.

Molluscum Contagiosum Virus Infection in an Epidermal Cyst / 대한피부과학회지

No abstract available.

Type B Pigmentary Demarcation Lines of Pregnancy Involving the Anterior Thighs and Knees

Pigmentary demarcation lines are abrupt transition lines between the areas of deeper pigmentation and the areas of lighter, normal pigmentation. Type B pigmentary demarcation lines involve the posterior medial portion of the lower extremities and are more commonly associated with pregnancy. We present a case of pigmentary demarcation lines of pregnancy with erythematous changes, involving both the anterior and posterior aspects of the lower extremities.

Proximal and Lateral Chromonychia with Capillary Proliferation on the Distal Nail Matrix

No abstract available.

Delayed Contact Dermatitis to Coral / 대한피부과학회지

Coral is a member of the class Anthozoa, which cause injury due to stings from their tentacles containing nematocytes or from their sharp-edged calcified outer skeletons. Sting from their nematocytes may cause coral poisoning and cause a rare type of contact dermatitis. A 24-year-old woman, who had been contacted to coral during skin-scuba diving in the Philippines 7 days before, was presented with multiple brownish plaques and patches with small vesicles on the dorsum of the left hand. Herein, we report a case of contact dermatitis to coral by the nematocyst stings of corals.

Delayed Contact Dermatitis to Coral / 대한피부과학회지

Coral is a member of the class Anthozoa, which cause injury due to stings from their tentacles containing nematocytes or from their sharp-edged calcified outer skeletons. Sting from their nematocytes may cause coral poisoning and cause a rare type of contact dermatitis. A 24-year-old woman, who had been contacted to coral during skin-scuba diving in the Philippines 7 days before, was presented with multiple brownish plaques and patches with small vesicles on the dorsum of the left hand. Herein, we report a case of contact dermatitis to coral by the nematocyst stings of corals.

Syringocystadenoma Papilliferum of the Back Combined with a Tubular Apocrine Adenoma

Syringocystadenoma papilliferum (SCAP) and tubular apocrine adenoma (TAA) are rare benign sweat gland tumors. SCAP and TAA may have a histopathologic overlap, but few cases of a SCAP combined with a TAA have been reported. Herein we describe an unusual case of a SCAP co-existing with a TAA located on the back of a 12-year-old girl.

Systemic Contact Dermatitis from Propolis Ingestion

Propolis, also known as bee glue, is a substance collected by worker bees and it is used as a material for constructing and maintaining their beehives. It has been used topically and orally by humans for its anti-inflammatory properties. However, the growing use of propolis has been paralleled by reports of allergic contact dermatitis as a reaction to the substance. Contact dermatitis with generalized cutaneous manifestations elicited by propolis ingestion has not been previously reported. Here we report on the first case of systemic contact dermatitis from propolis ingestion in a 36-year-old woman.

Giant Vascular Eccrine Spiradenoma

Giant vascular eccrine spiradenomas (GVESs) are a rare variant of the eccrine spiradenoma that develops from the sweat gland. It is different from the eccrine spiradenoma in its larger size and greater degree of vascularity. Bleeding and/or ulceration are common clinical features of this tumor, and are the reason why it is often clinically confused with a vascular or malignant tumor. Here, a rare case of GVES without bleeding or ulceration is reported.

A Case of Reactive Eccrine Syringofibroadenoma

Eccrine syringofibroadenoma is a rare adnexal tumor of eccrine ductal differentiation with variable clinical features. It manifests as either a solitary or multiple papules and nodules arranged in a symmetrical or linear pattern. The anatomical distribution is wide and includes the face, trunk, extremities, and rarely the nails. Histopathological findings show anastomosing cords and strands of uniform cuboidal cells surrounded by fibrovascular stroma. Herein, we report a case of reactive eccrine syringofibroadenoma which developed on the foot of a 37-year-old woman, after self-paring of tissue and subsequent infection and ulceration.

A Case of Nevus of Nanta / 대한피부과학회지

Nevus of Nanta is a melanocytic nevus with secondary ossification. Many theories involving external stimuli have been proposed to explain this rare condition; however, the origin of the ossification within the melanocytic nevus remains unknown. A 70-year-old woman presented with an asymptomatic solitary skin-colored papule with a central depression on the right malar area for one year. Histopathologic examination revealed an intradermal nevus with bone trabeculae. We herein report an interesting case of nevus of Nanta.

Breast Cancer Cutaneous Metastasis at Core Needle Biopsy Site

Cutaneous metastasis from breast cancer can occur by direct invasion, lymphatic and vascular spread as well as iatrogenic implantation. Metastasis that occurs by iatrogenic implantation after needle biopsy is very rare but the potential risk must be considered. In this report, we describe a case of breast cancer cutaneous metastasis that occurred by iatrogenic implantation following core needle biopsy. A 53-year-old woman presented with a 1x1 cm sized erythematous nodule at the biopsy site after breast conserving surgery for primary cancer. Histopathological findings confirmed cutaneous metastasis. The possibility of this consequence must be considered when performing needle biopsies.

Idiopathic Multiple Eruptive Milia Occurred in Unusual Sites

Milia are small, white, benign keratinous cysts that are frequently encountered. Multiple eruptive milia are rare, and are characterized by the development of milia that are more extensive in number and distribution than would be expected in primary milia. We report a case of a 19-year-old girl with tiny, white papules in her axillae and on her abdomen with a review of the relevant literature.

A Case of Tungiasis after Traveling to Congo / 대한피부과학회지

Tungiasis is an ectoparasitic disease that is caused by the penetration of Tunga penetrans into the epidermis of the host. Tungiasis is indigenous to South Americaand the Caribbean regions, but it has spread to Latin America, India, and sub-Saharan Africa. The area of soft skin such as the soles, toes, webs and subungual regions are the favored sites for sand flea embedding. As the flea enlarges within epidermis a pruritic, painful white or erythematous papulonodule develops. A black central punctum is characteristic. A 32-year-old woman presented with a small black crust on the right sole after traveling to an endemic area(Congo). Histopathologic examination revealed the internal organs of the arthropod embedded intothe epidermis, which allowed a definitive diagnosis of tungiasis. Although tungiasis is common in endemic areas, there has been no report of tungiasis in the Korean literature. We report herein an interesting case of tungiasis in a patient after traveling to Congo.

Effects of Repeated Nicotine Treatment on the Changes in Glutamate Receptor Subunits Levels in Mesocorticolimbic Dopamine Areas

Recent studies suggest that alterations in glutamate receptor subunit levels in mesocorticolimbic dopamine areas could account for neural adaptations in response to psychostimulant drugs. Although many drugs of abuse induce changes in ionotropic glutamate receptor subunits in mesocorticolimbic dopamine areas, the changes of ionotropic glutamate receptor subunits by repeated nicotine treatment in these areas are not known. To answer this question, we injected male Sprague-Dawley rats twice daily with nicotine (0.4 mg/kg) or saline (1 ml/kg) for 10 days. The immunoreactivity of NR1, GluR1, and GluR2 glutamate receptor subunits was examined 16~18 h after the last injection of saline or nicotine. Repeated nicotine treatment significantly increased NR1 levels in the ventral tegmental area (VTA). In addition, repeated nicotine treatment showed a tendency towards an increase in GluR1 levels in the VTA as well as in striatum. However, there was no significant change in glutamate receptor subunits in other areas including nucleus accumbens (NAc). These results demonstrate that repeated nicotine treatment increases NR1 levels in VTA similarly to other drugs of abuse, suggesting that elevated glutamate receptor subunits in the VTA, but not NAc may be involved in the excitation of mesocorticolimbic dopamine neurons by nicotine.

Chronic mild stress decreases survival, but not proliferation, of new-born cells in adult rat hippocampus

New-born cells continue to proliferate and survive to become mature granule cells in adult rat hippocampus. Although this process, known as neurogenesis, is inhibited by acute stress, it is not clear whether chronic stress affects neurogenesis. To determine whether chronic mild stress (CMS) influences neurogenesis in the adult rat hippocampus, male Sprague-Dawley rats were exposed to CMS and administered bromodeoxyuridine (BrdU) before or after CMS to observe the survival/differentiation or proliferation of new-born cells, respectively. In addition, we measured brain-derived neurotrophic factor (BDNF) mRNA in the granule cell layer (GCL) of the hippocampus, because BDNF is known to play an important role in the survival of new-born cells. CMS significantly decreased the survival of newborn cells in the GCL, but did not influence the proliferation or differentiation of new-born cells. CMS did not affect the proliferation and survival of new-born cells in the hilus. In addition, CMS did not change BDNF mRNA levels in the GCL. These results demonstrate that CMS reduces the survival of new-born cells but not of their proliferation, suggesting that repeated mild stress could influence a part of neurogenesis, but not the whole part of neurogenesis. These results raise the possibility that the survival of new-born cells may be suppressed in the presence of normal BDNF mRNA levels in GCL.