Design of intelligent positioning system for mobile medical equipment in operating room based on Bluetooth technology / 医疗卫生装备

Objective To develop an intelligent positioning system for mobile medical equipment in the operating room based on Bluetooth technology to enhance medical equipment management efficiency.Methods The intelligent positioning system for mobile medical equipment used received signal strength indication(RSSI)algorithm and multi-gateway trajectory filtering algorithm to realize Bluetooth positioning,which was composed of Bluetooth gateways,Bluetooth beacons,Bluetooth labels and a background data processing platform.The Bluetooth gateway consisted of an active power over ethernet(POE)module,a DC power module,a CPU,a Wi-Fi module and a Bluetooth module;the Bluetooth beacon included a beacon control unit,a Bluetooth transmitter module and a Bluetooth receiver module;the Bluetooth label was made up of a microcontroller unit(MCU),a Bluetooth module,an anti-temper switch and a accelerometer;the data processing platform had the front end developed with Vue architecture and the back end with Java language.Results The system developed could accurately locate the medical equipment in the operating room without electromagnetic interference to other medical devices.Conclusion The system developed gains advantages in high positioning accuracy,low electromagnetic interference,high stability and reliability and low cost,which improves the positioning and management efficiency of medical equipment under the premise of ensuring safety.[Chinese Medical Equipment Journal,2023,44(9):29-32]

Design and application of mobile intelligent inventory system for medical equipment / 医疗卫生装备

Objective To design a mobile intelligent inventory system for medical equipment to solve the problems of medical equipment management in efficiency and accuracy due to manual inventory.Methods A mobile intelligent inventory system for medical equipment was designed with radio frequency identification(RFID)technology,optical character recognition technology and wireless network technology,which was composed of a photo acquisition device,an inventory workstation,a wireless router,a mobile cart,a RFID barcode printer and a mobile power source.The photo acquisition device realized equipment image collection with a photography App in the cell phone or tablet computer;the inventory workstation consisted of an offline inventory system and an equipment nameplate recognition system,which built inventory tasks with Tomcat Web service and identified equipment nameplate information through feature-based learning algorithms;the RFID barcode printer controlled label printing by an offline inventory system embedded into its driver.Results The system developed executed medical equipment inventory and labeling simultaneously,which established electronic file for each piece of equipment to realize accounts corresponding to the equipment accurately.Conclusion The inventory system developed enhances the efficiency of medical equipment inventory,standardizes the flow of medical equipment ledger management and provides support for life-cycle management of medical equipment.[Chinese Medical Equipment Journal,2023,44(11):45-49]

Early changes of coagulation function in a swine traumatic model within 1 hour after traumatic hemorrhagic shock induced by Gunshot injury / 解放军医学杂志

Objective To explore the potential mechanism of traumatic coagulopathy through investigating the periodic change of hemodynamics, acid-base system, and coagulation system within 1 hour after traumatic hemorrhagic shock. Methods Adult healthy Landrace pigs were anesthetized to establish a model of hemorrhagic shock-induced by gunshot wounds. Vital signs, Hemodynamic parameters were monitored, and arterial blood gas, routine coagulation as well as thromboelastogram were tested at 15 minutes before the injury, shock point, 10 minutes after the shock, 30 minutes after the shock, and 1 hour after the shock, respectively. Results Among the 16 Landrace pigs that were examined, the mean total blood loss was (1444.22±205.50) ml with a 1-hour survival rate of 68.75%. Among the 11 pigs which survived over 1 hour, Hemodynamic and arterial blood gas analysis showed characteristics of stages. Analysis coagulation test showed that R value, PT and APTT are periodically decreased. The MA value decreased significantly from injury to 10 minutes after shock point (P<0.05), and LY30 showed a significant decreased from 10 minutes aftershock to 1-hour aftershock (P=0.038). In the correlation analysis of coagulation changes, there was a correlation between APTT value and heart rate, diastolic blood pressure, systolic blood pressure, MAP (P<0.05); R value was related to heart rate, SVI, systolic blood pressure, and MAP (P<0.05); MA value was related to BE, LAC, K+, PH, Ca2+, and SVI (P<0.05). Conclusion Within 1 hour after severe traumatic hemorrhagic shock, the coagulation system is in a hypercoagulable state. At 10 minutes after the shock, the fibrinolytic system is inhibited and the fibrinolysis is shut down, which may further aggravate the hypercoagulable state.

Preliminary study on the clinical value of noninvasive prenatal testing of fetal chromosomal copy number variations / 中国实用妇科与产科杂志

OBJECTIVE: To explore the clinical value of non-invasive prenatal testing(NIPT)for screening fetal chromosomal copy number variations(CNVs) and microdeletion/microduplication syndromes(MDs).METHODS: Retrospective analysis was made in the 10 005 women who received NIPT during the first trimester(15-20+ 6 weeks)from January,2012 to July,2017,at First People's Hospital of Yunnan Province,Department of Genetic Diagnosis Center.Among them 32 pregnant women were indicated fetal CNVs,25 of 32 pregnant women selected interventional prenatal diagnosis.Statistical analysis was made on the amniotic fluid/cord blood chromosome G band karyotype and high-throughput sequencing(NGS)genome copy number analysis was made,and relevant CNVs were searched and analyzed in the corresponding database;the consistency of CNVs found in NIPT with interventional prenatal diagnosis was statistically analyzed.RESULTS: During the second trimester(15-20+ 6 weeks),in the 10 005 pregnant women who received NIPT testing 32 cases were shown to have high risks of fetal CNVs,and the screening positive rate was 0.32%(32/10 005).In 25 high risk pregnant women who accepted invasive prenatal diagnosis via informed choice,14 women wereconfirmed as fetal CNVs,the positive predictive value(PPV)of NIPT being 56%(14/25),including 9 cases of microdeletion and 5 cases of microduplication.The sizes were between 587.75 kb and 36.05 Mb.The size and the start and end positions of CNVs found by NIPT were similar to those of fetal DNA samples detected by NGS.Among 14 cases of fetal CNVs,11 cases were identified as MDs,3 cases as unknown clinical significance.In 11 cases of MDs,8 cases were observed fetal chromosome structure abnormalities by karyotype analysis,10 cases were confirmed as de novo abbreviations,and 2 cases as originated from paternal same MD.After genetic counseling,10 pregnant women in 11 cases of MDs chose informed terminations,and one case chose continuing pregnancy.CONCLUSION: As a high-precision screening method,NIPT is expected to be an effective mean to screen for fetal CNVs,which can be used to detect highrisk chromosome microdeletion and microduplication CNVs of larger segments.High risk cases of fetal CNVs found by NIPT require invasive prenatal diagnosis for validation.

Interactive guided breathing technology / 中国医疗器械杂志

<p><b>OBJECT</b>Scientific guided breathing technology is to be studied based on the cardiopulmonary interaction.</p><p><b>METHODS</b>Heart rate variability was used as the target function to study the smoothly respiratory relaxation procedure in order to acquire the common pattern of regular and slow breathing.</p><p><b>RESULTS</b>Music based on the acquired common pattern was created and a musical pattern temporally-related to the breathing movement monitored by a sensor could be chosen to guide the breathing interactively.</p>

Design of a digital respiratory inductive plethysmography system / 中国医疗器械杂志

A new type of respiratory inductive plethysmography (RIP) has keen designed based on digital demodulation technique with equal relative error. Compared with former amplitude demodulation, digital modulation RIP can obtain more accurate measurements of respiration and reduce the signal interference and distortion. But the system's power consumption is still a problem which needs to be solved in the future design.