Rethinking COVID-19 Outbreak Impact

The world is going through a tough time and struggling with a pandemic COVID-19. An illness started from Wuhan city, now spread over almost all countries of the globe.Vaccination process is still going on and people will have to wait a long for complete eradication. Till then the only prevention is following social distancing, wearing mask, being in quarantine and isolation. World leaders are imposing lockdown in the countries with different intensity. In totality this is a challenging time, not just for the leaders, doctors, and police but for the normal people including private employees, daily wage earners and self employed individuals. Economic activities got a long halt. Every part of the population is getting affected. Emotions of stress, anxiety, anger, fear and frustration are obvious among people in this lockdown time. During this time Indian spirituality has been rebooted by many aspects. There is no doubt that India is the richest in its knowledge of Ayurveda, Ethos and Universe. Keeping this in mind existing literature of COVID-19 outbreak with special context to call for mental health and role of spiritual practices in mitigating the stress was searched with the help of different database. Published articles were represented in systematic form and summarize based on their methodologies and themes. So, this paper is trying to give a picture how with the help of Indian spiritual practices people can regain their faith and self-confidence since Indian Government is doing a lot with Ayurvedic preventions and connecting people with knowledge and peace by re telecasting great Indian tales like Ramayana, Mahabharata and Upanishad. Objectives of the study: Following are the main objectives of this study- Ÿ To investigate COVID-19 outbreak in India and its general impact on business and human. Ÿ To study re conceptualization of business strategies during and after lockdown. Ÿ To investigate need of mental health call in pandemic. Ÿ To understand role of spirituality in stress management during COVID-19 outbreak

Xanthogranulomatous pancreatitis: mass lesion of the pancreas simulating pancreatic carcinoma--a report of two cases.

Xathogranulomatous inflammation is well known in the gall bladder and kidney. Xanthogranulomatous pancreatitis has not been previously described. We report two cases of this new clinicopathologic entity. The first was a 50 years old male with cholelithiasis and progressive obstructive jaundice for 5 months. Radiology was suggestive of carcinoma head of pancreas and a Whipples procedure was performed. The second was a 36 years old male with choledocholithiasis and features of chronic pancreatitis. During pancreaticojejunostomy, a mass was found in the tail of pancreas, which was excised with a suspicion of carcinoma. Gross examination of both specimens showed firm grey white masses, demarcated from the surrounding pancreas but with infiltrative margins, and were thought to be carcinoma. Histopathological examination showed localized inflammation with numerous foamy histiocytes along with dilated ducts and microabscesses. A diagnosis of xanthogranulomatous pancreatitis was made in both instances. In view of clinical, radiological, operative and gross appearances of our cases simulating carcinoma, recognition of xanthogranulomatous chronic pancreatitis as a distinct clinicopathological entity seems important, analogous to similar lesions of the kidney and gall bladder.

Pre and post eradication gastric inflammation in Helicobacter pylori-associated duodenal ulcer.

BACKGROUND: Distribution and nature of gastritis are major determinants of clinical outcome of H. pylori infection. The gastric inflammatory changes associated with this infection in developing countries have not been systematically studied. AIMS: To evaluate the inflammatory changes in gastric antrum and corpus in patients with duodenal ulcer and H. pylori infection, before and after H. pylori eradication therapy. METHODS: Histology and H. pylori density were studied in gastric biopsies obtained from 53 consecutive patients with active duodenal ulcer and H. pylori infection. Biopsies were obtained before and 4 weeks after H. pylori eradication therapy, from the anterior and posterior walls of the antrum and corpus, and were evaluated according to the Sydney system. RESULTS: In the pre-H. py/ori eradication antral biopsies, chronic gastritis, active gastritis, atrophy, intestinal metaplasia (IM) and lymphoid follicles / aggregates were seen in 53 (100%), 49 (92%), 11 (21%), 7 (13%) and 28 (53%) patients, respectively. In the corresponding biopsies from gastric corpus, these changes were seen in 49 (92%), 23 (43%), 2 (4%), 2 (4%) and 8 (15%), respectively. All changes except IM were significantly more frequent and of higher grade in the antrum. The grade of chronic gastritis was significantly higher in antrum than corpus; the frequency of gastritis in the antrum and corpus was similar (100% vs. 92%). H. pylori density was also higher in the antrum and correlated well with the grades of chronic gastritis and activity at both sites. Eradication of H. pylori was achieved in 39 patients (74%), and led to significant decrease in gastritis; no change was seen in patients who did not eradicate the organism. CONCLUSIONS: Antral-predominant chronic gastritis and activity are present in more than 90% of patients with H. pylori infection associated with duodenal ulcer, and the grade of gastritis correlates with the density of the organism. Eradication therapy results in improvement of both chronic gastritis and activity.