1.
Indian J Lepr
; 2000 Jul-Sep; 72(3): 339-50
Article
Dans Anglais
| IMSEAR
| ID: sea-54262
2.
Indian J Lepr
; 1999 Jan-Mar; 71(1): 69-74
Article
Dans Anglais
| IMSEAR
| ID: sea-54626
3.
Indian J Lepr
; 1996 Jan-Mar; 68(1): 67-73
Article
Dans Anglais
| IMSEAR
| ID: sea-54265
4.
Indian J Lepr
; 1995 Oct-Dec; 67(4): 363-74
Article
Dans Anglais
| IMSEAR
| ID: sea-54232
Résumé
Various mechanisms for nerve damage in tuberculoid leprosy have been proposed. A common feature amongst them is the crucial role played by T-cells. Therefore, the present study was designed to determine the role of T-cells in the induction of nerve damage in leprosy using two different protocols for obtaining graded levels of T-cell depletion: (i) Cyclosporine A, for depletion of T-helper cells and (ii) Anti Thy 1.2, for total depletion of T-cells. The findings indicate that the early changes seen in the unmyelinated fibres may not involve T-cells. However, the later stages of nerve damage associated with demyelination are dependent on T-cell responses.
Sujets)
Animaux , Ciclosporine/pharmacologie , Maladies démyélinisantes/étiologie , Femelle , Alloanticorps/immunologie , Lèpre/microbiologie , Souris , Mycobacterium leprae/croissance et développement , Nerf ischiatique/anatomopathologie , Lymphocytes T/physiologie
5.
Article
Dans Anglais
| IMSEAR
| ID: sea-118994
6.
Indian J Lepr
; 1991 Jul-Dec; 63(3-4): 297-300
Article
Dans Anglais
| IMSEAR
| ID: sea-54538