Résumé
Background: Smoking is one of the main causes of death among adults worldwide. Aim: To characterize smoking among Chilean older people, according to sociodemographic and clinical variables. Material and Methods: Secondary analysis of data obtained during the National Health Survey 2009-10, selecting individuals aged 60 years and older. Expansion factors were used due to the complex design of the sample. Prevalence and characteristics of smoking were calculated, according to age, sex, educational level, marital status, healthcare insurance system and comorbidities. Results: Nineteen percent of older people were actual smokers, and 85% of these smokers were aged between 60 and 69 years. Forty-five percent were highly dependent to nicotine and 73% reported their intention to quit smoking. Conclusions: There is a high prevalence of tobacco smoking among Chilean older people. Prevention measures are needed.
Sujets)
Humains , Adulte d'âge moyen , Sujet âgé , Fumer/épidémiologie , Chili/épidémiologie , Prévalence , Enquêtes de santéRésumé
Background: Throughout medical education, students are gradually incorporated into authentic clinical practice scenarios. Aim: To describe the use of clinical learning strategies by Chilean students and compare them according to sex and year of training. Material and Methods: The Clinical Learning Strategies Questionnaire (CEACLIN) was applied to 336 students from the 4th to 6th year of medicine at a Chilean university. Results: The most frequently reported strategies were related to the search for autonomy, reliable environments for learning, observation of others and attention to emotions. The less frequent was the handling of academic burden. Gender accounted for significant differences in eight of the 11 strategies identified by CEACLIN, while years of training accounted for five of the 11. The cluster analysis identified two groups: the first group comprised nine CEACLIN strategies, with a slightly higher proportion of women and 5th and 6th year students. The second group consisted mainly of men in the 4th year. Conclusions: Reported strategies include a set of actions oriented to the development of autonomy and confidence through the search for valid information and learning from and with others. These findings are associated with sex and year of training.
Sujets)
Humains , Mâle , Femelle , Étudiant médecine , Stage de formation clinique , Enseignement médical/méthodes , Apprentissage , Universités , Analyse de regroupements , Chili , Enquêtes et questionnaires , Compétence cliniqueRésumé
Background: Simulation is a useful training tool for undergraduate medical students. A valid instrument is needed to assess students' perception of simulation workshops. Aim: To adapt and validate an instrument to assess the undergraduate medical student's perception of simulation workshops of clinical procedures. Material and Methods: Delphi Methodology was used to adapt the instrument. Exploratory and confirmatory analyses were performed to determine the construct validity and Cronbach's Alpha (0 to 1) for internal consistency of the instrument. Results: A Delphi panel of 10 experts adapted a seven-item questionnaire (Likert scale 1-5; ranging from 7 to 35) and four open-questions. After 3-delphi-rounds, the instrument was administered to 210 students in six simulation training programs (Paracentesis, Cardiopulmonary Resuscitation, Airway management, Sutures, Thoracentesis and Nursing Procedures). The instrument was considered unidimensional in the factorial analysis. The overall median (Q1-Q3) score was 34 ranging from 32 to 35 and the Cronbach Alpha coefficient was 0.72, indicating a good reliability. Conclusions: The perception questionnaire is a useful and reliable instrument to assess students' perceptions of clinical simulations.
Sujets)
Humains , Perception , Étudiant médecine/psychologie , Enquêtes et questionnaires/normes , Compétence clinique/normes , Enseignement médical premier cycle/méthodes , Formation par simulation/méthodes , Normes de référence , Procédures de chirurgie opératoire/enseignement et éducation , Procédures de chirurgie opératoire/psychologie , Reproductibilité des résultats , Analyse statistique factorielle , Méthode Delphi , Rétroaction formativeRésumé
Background: Cocaine users tend to have a higher frequency of risk behaviors. Aim: To compare risk behaviors of out of treatment Cocaine Base Paste (CBP) and Cocaine Hydrochloride (CH) users, by means of Privileged Access Interviewing in a one year prospective study. Material and Methods: Twenty eight interviewers were trained to recruit and administer a questionnaire on substance use patterns and related risk behaviors. Intentioned sampling was carried out in four municipalities of Santiago, Chile. Subjects who used CBP (group 1) or CH (group 2) at least once in the last month, with primary current use of CBP (group 1) or CH (group 2), and without treatment for substance abuse in the last six months were interviewed. Generalized Estimating Equations (GEE) were employed to compare risk behaviors during follow up. Results: Four hundred and two of 467 subjects (86.1%) were followed up for one year. CBP users (n = 204) reported greater frequency of self inflicted injuries (Odds Ratio (OR): 1.97 [95% confidence intervals (CI): 1.073.66]) and suicide attempts (OR: 2.68 [95% CI: 1.196.01]) than CH users. Conclusions: CBP users had a greater frequency of self inflicted injuries and suicide attempts, both life threatening risk behaviors, than CH users. This profile shows the high vulnerability of CBP users and should encourage further research and design of outreach interventions, particularly focused on this group.
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Humains , Mâle , Femelle , Adulte , Jeune adulte , Tentative de suicide/statistiques et données numériques , Comportement auto-agressif/épidémiologie , Troubles liés à la cocaïne/thérapie , Comportement dangereux , Prise de risque , Facteurs socioéconomiques , Chili/épidémiologie , Facteurs sexuels , Méthodes épidémiologiques , Facteurs de risque , Facteurs âges , Résultat thérapeutique , Comportement toxicomaniaque/complications , Comportement toxicomaniaque/épidémiologie , Troubles liés à la cocaïne/complicationsRésumé
Background: Multiple clinical trials have demonstrated the benefits of adjuvant 5-fluorouracil-based chemotherapy for patients with resectable colon cancer (CC), especially in stage III. Aim: To describe the clinical characteristics of a cohort of CC patients treated at a single university hospital in Chile since 2002, and to investigate if chemotherapy had an effect on survival rates. Material and Methods: Review of a tumor registry of the hospital. Medical records of patients with CC treated between 2002 and 2012 were reviewed. Death certificates from the National Identification Service were used to determine mortality. Overall survival was described using the Kaplan-Meier method. A multivariate Cox proportional hazard regression model was also used. Results: A total of 370 patients were treated during the study period (202 in stage II and 168 in stage III). Adjuvant chemotherapy was administered to 22 and 70% of patients in stage II and III respectively. The median follow-up period was 4.6 years. The 5-year survival rate for stage II patients was 79% and there was no benefit observed with adjuvant chemotherapy. For stage III patients, the 5-year survival rate was 81% for patients who received adjuvant chemotherapy, compared to 56% for those who did not receive chemotherapy (hazard ratio (HR): 0.29; 95% confidence interval (CI): 0.15-0.56). The benefit of chemotherapy was found to persist after adjustment for other prognostic variables (HR: 0.47; 95% CI: 0.23-0.94).Conclusions: Patients with colon cancer in stage III who received adjuvant chemotherapy had a better overall survival.
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Humains , Mâle , Femelle , Adulte , Adulte d'âge moyen , Sujet âgé , Sujet âgé de 80 ans ou plus , Jeune adulte , Protocoles de polychimiothérapie antinéoplasique/administration et posologie , Tumeurs du côlon/traitement médicamenteux , Fluorouracil/administration et posologie , Pronostic , Taux de survie , Études rétrospectives , Résultat thérapeutique , Traitement médicamenteux adjuvant , Tumeurs du côlon/mortalité , Tumeurs du côlon/anatomopathologie , Stadification tumoraleRésumé
Background: Teaching methods of the undergraduate medical curriculum change considerably from the first years to clinical training. Clinical learning occurs in complex and varied scenarios while caring for patients. Students have to adapt their learning approaches and strategies to be able to integrate theory and clinical practice and become experiential learners. Aim: To identify the strategies used by medical students to learn during the initial clinical years, as reported by students themselves and by their clinical tutors. Material and Methods: We performed eight focus group discussions with 54 students enrolled in years three to six and we interviewed eight clinical tutors. Both focus group discussions and interviews were audio recorded, transcribed and analyzed according to Grounded Theory. Results: Four main themes were identified in the discourse of both students and tutors: Strategies oriented to theoretical learning, strategies oriented to experiential learning, strategies for integrating theory and practice and strategies oriented to evaluation. The mentioning of individual differences was present across the reports of both students and tutors. Conclusions: Students use a rich variety of strategies to face the challenges of clinical learning. Both students and tutors recognize that the learning approaches and strategies vary according the nature of the task and individual differences. The responses of students bring particular knowledge of the approaches used for the theoretical and practical integration and delve into the social dimension of learning.
Sujets)
Femelle , Humains , Mâle , Évaluation des acquis scolaires , Habitudes , Apprentissage , Perception , Étudiant médecine/psychologie , Compétence clinique , Enseignement médical premier cycle , Groupes de discussion , Entretiens comme sujet , Recherche qualitativeRésumé
Background: Toxoplasmosis, cosmopolitan parasitic zoonosis often found in humans, is transmitted mainly by food and water, and is considered a significant risk of morbidity and mortality in pregnant women, newborns and immunocompromised patients. Objective: To identify the information about this zoonosis and its first reports in Chile. Materials and Methods: Review of publications in Pubmed, Mesh search of systematic reviews, case studies, cross-sectional studies, systematic reviews, meta-analysis and specialty publications. In addition, other publications in parasitology journals were analyzed. Conclusions: There are reports of the presence of this disease in Chile for 60 years. During this time several differences in prevalence depending on geographic location, age and education level of the population have been detected. There is low epidemiological vigilance and lack of specific official preventive measures for this disease, despite the possible introduction of new parasite genotypes of an increased virulence and pathogenicity in the country through the importation of meat. New enigmas have arisen in relation to this disease associating it with Alzheimer, Parkinson’s disease, autism, learning disabilities, among others.
Antecedentes: La toxoplasmosis, zoonosis parasitaria cosmopolita frecuente en humanos, es transmitida principalmente por alimentos y agua, constituye un riesgo importante de morbilidad y mortalidad, en mujeres embarazadas, recién nacidos e inmunodeprimidos. Objetivo: Caracterizar la información existente de esta zoonosis y sus primeros reportes en Chile. Materiales y Métodos: Revisión de publicaciones en PubMed, búsqueda MeSH de revisiones sistemáticas, estudios de casos, estudios transversales, revisiones sistemáticas, meta-análisis y publicaciones de la especialidad. Conclusiones: Existen reportes de esta enfermedad en Chile desde hace 60 años. Durante ese período se han observado diferencias en su prevalencia dependiendo de la ubicación geográfica, edad y nivel de educación de la población en riesgo. Se observa baja vigilancia epidemiológica y escasas medidas preventivas oficiales específicas, posible introducción de nuevos genotipos del parásito de mayor virulencia y patogenicidad, a traves de la importación de carnes. Surgen, en torno a esta enfermedad, nuevos enigmas que la asocian a patología como Alzheimer, Enfermedad de Parkinson y problemas de aprendizaje, entre otros.
Sujets)
Animaux , Femelle , Humains , Grossesse , Toxoplasmose/épidémiologie , Zoonoses/épidémiologie , Chili/épidémiologie , Prévalence , Facteurs de risqueRésumé
Background: Upon the beginning of pre-clerkship years, medical students must develop strategies to learn from experience and to improve their relational skills to communicate with patients. Aim: To develop an instrument to identify the strategies used by medical students to learn in clinical contexts. Material and Methods: Using a Delfi technique to reach consensus, a national panel of students and clinical teachers from 15 Chilean medical schools analyzed an 80-item questionnaire built from perceptions of Chilean students and teachers from one medical school. After two Delfi rounds and a pilot application, a 48-item questionnaire was obtained. Its reliability and construct validity were assessed by Cronbach alpha coefficient and factor analysis, respectively, on the base of an application to 336 medical students. Results: The questionnaire developed, named CEACLIN, is highly reliable (α= 0.84). Its inner structure is made of eleven factors: Autonomy, Solving doubts and problems, Searching and organizing information, Proactivity, Reaching to others, Paying attention and emotions, Searching for trust, Evading burden, Coping with burden, Motivation and Postponing the personal life. All together, these factors account for 47.4 % of the variance. Conclusions: CEACLIN is a valid, reliable and easy to use instrument suited to identify students´ strategies to learn in pre-clerkship years. Many of its items allude to concepts of theories of experiential learning and motivation. We hope that CEACLIN will be of value to medical students and clinical teachers to improve the learning and teaching of clinical reasoning and communication skills.
Sujets)
Femelle , Humains , Mâle , Stage de formation clinique/normes , Évaluation des acquis scolaires/méthodes , Apprentissage , Étudiant médecine/statistiques et données numériques , Chili , Compétence clinique , Méthode Delphi , Analyse statistique factorielle , Reproductibilité des résultats , Enquêtes et questionnairesRésumé
Background: Feedback is one of the most important tools to improve teaching in medical education. Aim: To develop an instrument to assess the performance of clinical postgraduate teachers in medical specialties. Material and Methods: A qualitative methodology consisting in interviews and focus-groups followed by a quantitative methodology to generate consensus, was employed. After generating the instrument, psychometric tests were performed to assess the construct validity (factor analysis) and reliability (Cronbachs alpha). Results: Experts in medical education, teachers and residents of a medical school participated in interviews and focus groups. With this information, 26 categories (79 items) were proposed and reduced to 14 items (Likert scale 1-5) by an experts Delphi panel, generating the MEDUC-PG14 survey, which was answered by 123 residents from different programs of medical specialties. Construct validity was carried out. Factor analysis showed three domains: Teaching and evaluation, respectful behavior towards patients and health care team, and providing feedback. The global score was 4.46 ± 0.94 (89% of the maximum). One teachers strength, as evaluated by their residents was respectful behavior with 4.85 ± 0.42 (97% of the maximum). Providing feedback obtained 4.09 ± 1.0 points (81.8% of the maximum). MEDUC-PG14 survey had a Cronbachs alpha coefficient of 0.947. Conclusions: MEDUC-PG14 survey is a useful and reliable guide for teacher evaluation in medical specialty programs. Also provides feedback to improve educational skills of postgraduate clinical teachers.
Sujets)
Humains , Enseignement médical/normes , Corps enseignant et administratif en médecine/normes , Plan de recherche/normes , Groupes de discussion , Entretiens comme sujet , Psychométrie , Recherche qualitative , Reproductibilité des résultats , Enquêtes et questionnaires , Enseignement/méthodes , Enseignement/normesRésumé
Background: In 2007, a Clinical-Case-Portfolio (CCP) was introduced as a new assessment instrument for fourth grade undergraduate medical students. Since then, several changes have been implemented such as reduction on the number of clinical cases, peer review and the introduction of virtual patient to the portfolio. Aim: To describe the virtual patient model incorporated to the CCP and assess the perception of this change and its effects on the performance of undergraduate students. Material and Methods: Virtual patients were implemented based on prototype clinical cases with specific syndromes. Students perceptions about CCP before and after the introduction of virtual patients were evaluated using a validated questionnaire that was answered voluntarily and anonymously. Results: Overall perception of CCP significantly improved after the incorporation of virtual patients (97.1 ± 24.9 and 111.3 ± 25.7 points; 57.8 and 66.2% respectively). The same improvements were observed for the domains Student Learning, Organization and Evaluation, Teaching Methodology and Integration. In both years, students obtained high grades in CCP evaluations. However CCP grades were not significantly correlated with integrated final grades. Conclusions: The incorporation of virtual patients improved undergraduate students perception of CCP.
Sujets)
Animaux , Souris , Apoptose , Axine/métabolisme , Activation enzymatique , Poly(ADP-ribose) polymerases/métabolisme , Protein-Serine-Threonine Kinases/antagonistes et inhibiteurs , Adénosine triphosphate/métabolisme , Facteur inducteur d'apoptose/génétique , Facteur inducteur d'apoptose/métabolisme , Aurora kinases , Lignée cellulaire , Membrane cellulaire/métabolisme , Membrane cellulaire/physiologie , Mitochondries/métabolisme , Inhibiteurs de protéines kinases/pharmacologie , Interférence par ARN , Imagerie accéléréeRésumé
Background: Women in childbearing ages (WCBA) represent a strategic intervention group to reverse the global trend of increasing obesity. Aim: To conduct a review of studies reporting obesity prevalence in WCBA in Chile in the last 25 years. Material and Methods: To describe obesity prevalence, we used three approaches, namely qualitative review of studies describing obesity prevalence in WCBA and a comparative study of the prevalence of obesity, overweight, abdominal and morbid obesity in WCBA from 2003 and 2009-10 National Health Surveys (ENS). Finally, nutrition status trends of pregnant women in the period 1987-2013 were plotted. Results: According to ENS, obesity prevalence exceeded 20% and excess weight 50%, both in 2003 and 2009-10 surveys. We found seven population studies, being difficult to compare them due to the heterogeneity of obesity definitions, design, and populations. Population studies showed that the prevalence of obesity increases along with age. The higher prevalence of obesity in WCBA aged 20 to 43 years was found in the city of San Carlos in 2007 (35.5%). The lowest was found in female university students, ranging from 0% to 5.9%. Obesity in pregnant women increased from 12.9% to 32.2% in the period 1987-2004 and from 20.3% to 26.3% in the period 2005-2013. Conclusions: There is a high and increasing prevalence of obesity among women in childbearing age, whether pregnant or not-pregnant.
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Adolescent , Adulte , Femelle , Humains , Adulte d'âge moyen , Grossesse , Jeune adulte , Fécondité/physiologie , Obésité/épidémiologie , Répartition par âge , Chili/épidémiologie , Prévalence , Facteurs tempsRésumé
Antecedentes: Son diversos los motivos que pueden afectar la calidad de vida (CV) de la mujer con cáncer cérvicouterino (CC), enfrentan cambios en la esfera física y sexual, como también social y psicológica. Objetivo: Describir la CV de un grupo de mujeres con CC y relacionar sus diferentes dimensiones con el tipo de tratamiento y la etapa del cáncer. Método: Estudio analítico realizado en un grupo de 127 mujeres con CC del área Sur Oriente de Santiago. Para la medición de CV se utilizo el instrumento EORTC QLQ-C30. Resultados: Las mujeres con mayor edad presentaron peor calidad de vida respecto al dominio físico. El tratamiento que la mujer recibe se relaciona con el dominio físico. No existen diferencias en la calidad de vida según las etapas FIGO. En el análisis multivariado el tipo de tratamiento y su interacción con la edad predicen la dimensión física, del rol, funcionamiento emocional y algunos síntomas como insomnio y diarrea. Conclusión: Evaluaciones de CV durante el curso de la enfermedad son útiles para la proyección de los resultados en salud a mediano y largo plazo y debiera incorporarse en la evaluación de las pacientes con CC de forma rutinaria y estandarizada, con el objetivo de realizar intervenciones apropiadas según la evidencia reportada.
Background: Quality of life (QOL) in women with cervical cancer can be affected by different reasons, because those women face not only changes in the physical and sexual domains, but also in social and psychosocial. Aim: To describe the QOL of a group of women with cervical cancer (CC) and to relate its different dimensions to the treatment and stage of cancer. Method: Analytical study was conducted on a group of 127 women with CC. Results: The age of women negatively correlated with the physical dimension. The type of treatment correlated negatively the physical, role and social domain, and it correlated positively with the fatigue symptom. The FIGO stage does not correlate in the univariate analysis. The type of treatment, with or without age interaction, predicts the physical, role, emotional domain and some symptoms such as insomnia and diarrhea in the multivariate analysis. Conclusion: QOL assessments during the course of CC disease are useful to projecting health outcomes to medium and long term and it should be incorporated as a routinely and standardized evaluation in order to make appropriate interventions.
Sujets)
Humains , Adulte , Femelle , Tumeurs du col de l'utérus/psychologie , Qualité de vie , Études transversales , Analyse multifactorielle , Enquêtes et questionnairesRésumé
Background: The transition to the clinical courses represents a major challenge for medical students who are expected to become experiential learners, able to integrate theory and practice in the context of patient care. There are questions about how students face this challenge. Aim: To understand and compare the perceptions of students and clinical tutors on how medical students learn during the transition to the clinical levels of the curriculum. Material and Methods: We performed eight focus group discussions with 54 students enrolled in years three to seven and we interviewed eight clinical tutors. Both students' focus group discussions and tutors' interviews were audio recorded, transcribed and analyzed according to the Grounded Theory. Results: Nine main themes emerged from the analysis of students' opinions and six from the tutors' views. The following themes were common to both students and educators: educational activities, actors, clinical settings, learning strategies, transition markers and tutor's role. Educators emphasized the importance of curricular courses' design and students, that of emotions, adaptation and self-care strategies, and threats to learning. Conclusions: There is a common core of students' and clinical tutors' perceptions about the relevance of practical activities, social interactions and context in the development of students' learning and adaptation strategies during the transition to the clinical levels of the curriculum. These results are related to social and cultural theories of learning. Thus we propose a model for early clinical learning that might help to stimulate the reflection of students and medical educators regarding clinical learning and contribute to the development of interventions that improve the clinical learning and teaching practices.
Sujets)
Femelle , Humains , Mâle , Enseignement médical , Enseignement médical premier cycle , Corps enseignant et administratif en médecine , Perception , Compétence clinique , Groupes de discussion , Apprentissage , Étudiant médecineRésumé
Supraphysiological levels (SFL) of serum folate (SF) derived from flour fortification with folic acid (FA) could be risky among older adults with low vitamin B12 (B12) levels. Aim: To describe and analyze SF and B12 levels in older Chileans and to identify risk groups. Material and Methods: Participants were 1.043 older people aged ≥ 65 years from the National Health Chilean Health Survey 2009-2010 (ChNHS 2009-10), a multistage stratified random sample, representative of the national population. SF (µg/L) and B12 (pg/ml) were determined in fasting samples by competitive chemoluminescence immunoassay. Mean, deciles and percentiles 5 and 95th were calculated. We defined SF categories: < 4.4 (deficit); 4.41-20 (normal) and SFL: 20.01-25.6; 25.6-29 and > 29 µg/L (80th percentile of the distribution) and vitamin B12 categories: ≤ 200 (deficit); 200.1-299.5 (marginal deficit) and > 299.5 (normal). Prevalence rates, multiple and logistic regression models were used and adjusted by sex and age, educational level and residence area. Results: SF and B12 mean and 95th percentiles were 21.2 ± 0.56/38.6 µg/L and 348.4 ± 7.6/637(pg/ml) respectively. Forty nine percent of participants had SFL. Folate and B12 deficiency were present in 0.3 and 8.1% of participants, respectively. Men had significantly lower prevalence of SFL > 29 µg/L (OR adjusted odds ratio 0.47 95% confidence intervals: 0.26-0.84). B12 showed no significant variation by age and sex. The prevalence of SFL associated with B12 deficiency was 4.1%. No statistically significant association was observed between levels of folate and B12. Conclusions: Folate deficit is almost inexistent, but a significant percentage of participants had SFL suggesting the need for revising the current wheat flour fortification levels.
Sujets)
Sujet âgé , Femelle , Humains , Mâle , Adulte d'âge moyen , Carence en acide folique/sang , Acide folique/sang , /sang , Chili/épidémiologie , Carence en acide folique/épidémiologie , Enquêtes de santé , Odds ratio , Surveillance de la population , Prévalence , Facteurs de risque , /épidémiologieRésumé
Training of postgraduate medical specialty program managers (PMSPM) is essential for the proper development of their programs. Aim: To identify the main training needs of PMSPM at a medical school. Material and Methods: A mixed-methodology approach was implemented including focus group/interviews and the administration of the Program Managers Training Needs Assessment Questionnaire (PROMANAQ) developed by an expert panel with 59 items (with two sections: relevance/performance-self-perception). Higher priority was assigned to items with high relevance and low performance. Results: Forty five PMSPM completed the PROMANAQ (81.8% response rate). Both sections of PROMANAQ were highly reliable (Cronbach alpha of 0.95/0.97 for relevance/performance-self-perception, respectively). The items with higher priority value were evaluation of clinical educators, evaluation of teaching programs and accreditation of programs. Ten PMSPM were included in the focus group (18.2% of the universe). The findings of the qualitative component were concordant with the areas explored in the questionnaire. Conclusions: The PROMANAQ is valid and reliable to identify the training needs of PMSPM. The views of PMSPM must be taken into account for faculty development planning.
Sujets)
Adulte , Femelle , Humains , Mâle , Adulte d'âge moyen , Formation continue/organisation et administration , Corps enseignant , Formation en interne/méthodes , Écoles de médecine/statistiques et données numériques , Chili , Évaluation des besoins , UniversitésRésumé
Background: Determination of Alanine aminotransferase serum levels ([ALT]s) is a sensitive ana reliable test for liver diseases. Aim: To report the prevalence of abnormal [ALT]s in Chilean population and to identify associated variables. Methods: We analyzed data from a random sub-sample of 2,794 adults surveyed during the second Chilean National Health Survey. Abnormal [ALT]s were defined by using three different cut-off values (COV), two fixed COV (COV1: > 30 IU/L in men and > 19 IU/L in women and COV2 pre-defined by the performing laboratory) and a COV adjusted by age, weight and sex (COV3 > 31 IU/L for women and > 44 IU/L and men > 42 IU/L and > 66 IU/L with a BMI > 23). Logistic regression analysis was performed to determine risk factors for elevated [ALT]s Results: Mean [ALT]s values were 30.14 I U/L in men and 22.03 IU/L in women. The observed prevalence of abnormal [ALT]s defined by different COV were 38%, 11.5%, and 8.1% for COV1, COV2 and COV3 respectively. Variables independently associated to abnormal [ALT]s in a multivariate analysis were the following: serum gamma-glutamyl-transpeptidase (OR: 1.055 [95% CI 1.033-1.078]) and body mass index (OR:1.13 [95% CI 1.09-1.17]). Variables inversely associated with abnormal [ALT]s (COV1) were mole gender (OR-.0.976 [95% CI 0.96-0.99) and HDL-cholesterol (OR:0979 [95% CI 0.96-0.99]). Conclusions: Independently of the COV used, Chilean population exhibits a high prevalence of abnormal [ALT]s which may reflect a significant burden of liver disease. Non-alcoholic fatty liver disease could be a major contributor to elevated [ALT]s considering the association of abnormal [ALT]s and metabolic variables.
Sujets)
Adulte , Femelle , Humains , Mâle , Alanine transaminase/sang , Marqueurs biologiques/sang , Chili , Enquêtes de santé , Maladies du foie/diagnostic , Maladies du foie/enzymologie , Prévalence , Valeurs de référence , Facteurs de risque , Sensibilité et spécificitéRésumé
Background: The Postgraduate Hospital Education Environment Measure (PHEEM) questionnaire, is a valid and reliable instrument to measure the educational environment (EE) in postgraduate medical education. Aim: To evaluate the EE perceived by the residents of a postgraduate training program using the PHEEM. Material and Methods: The PHEEM was applied in 2010-2011 in 35 specialty programs. We calculated their individual results and compared means of both global and individual domain scores of the PHEEM, by gender, university of origin and nationality. Cronbach's alpha coefficients and D study (Generalizability theory) were performed for reliability. Results: Three hundred eighteen residents were surveyed (75.7% of the total universe). The mean score of the PHEEM was 105.09 ± 22.46 (65.7% of the maximal score) which is considered a positive EE. The instrument is highly reliable (Cronbach's alpha = 0.934). The D study found that 15 subjects are required to obtain reliable results (G coefficient = 0.813). There were no significant differences between gender and university of origin. Foreigners evaluated better the EE than Chileans and racism was not perceived. The programs showed a safe physical environment and teachers with good clinical skills. The negative aspects perceived were a lack of information about working hours, insufficient academic counseling, and scanty time left for extracurricular activities. Conclusions: This questionnaire allowed us to identify positive aspects of the EE, and areas to be improved in the specialty programs. The PHEEM is a useful instrument to evaluate the EE in Spanish-speaking participants of medical specialty programs.
Sujets)
Femelle , Humains , Mâle , Enseignement spécialisé en médecine/normes , Enquêtes et questionnaires/normes , Environnement social , Brésil , Reproductibilité des résultatsRésumé
Introduction: The human papilloma virus (HPV) is a common sexually transmitted infection in young people and recognized as the most important risk factor for cervical cancer (CC). Aim: To describe the degree of knowledge that a group of Chilean teenagers have of HPV infection, CC, and its relationship with preventive behavior. Methods: This is an analytical study, with a random sample of 226 adolescents from three public schools of the Metropolitan Region in Santiago. Results: A fifth of the interviewed students did not know there was a HPV vaccine. Multiple sexual partners was indicated as a risk factor of CC by 70.8% and of HPV infection by 78.3% of them; while 60.3% identified inheritance as a risk factor. HPV transmission through unprotected sexual relations was identified by 68.2% of the sample. Of sexually active adolescents, condom use during sexual relations was reported by 31.1%. The adolescents who use condoms significantly have more knowledge regarding the number of sexual partners and age of first sexual intercourse as a risk factor for CC. Conclusion: adolescents know about HPV transmission, however, the preventing conducts are not related to this information.
Introducción: El virus papiloma humano (VPH) es una infección de transmisión sexual frecuente en población joven, y reconocido como el factor de riesgo más importante para desarrollar cáncer cérvico-uterino (CC). Objetivo: Describir el grado de conocimiento que tiene un grupo de adolescentes chilenas en relación al CC, al VPH y su relación con las conductas preventivas. Métodos: Estudio analítico, con una muestra aleatoria de 226 adolescentes de tres colegios municipalizados de la Región Metropolitana. Resultados: El 20% de la muestra desconoce la presencia de una vacuna contra el VPH. Las adolescentes señalan como factor de riesgo para desarrollar CC tener múltiples parejas sexuales (70,8%), VPH (78,3%) y la herencia (60,3%). La transmisión del VPH mediante relaciones sexuales sin protección es reconocida por 68,2% de la muestra. El 31,1% de las adolescentes sexualmente activas usa condón durante las relaciones sexuales. Aquellas adolescentes que usan condón señalan un conocimiento significativamente mejor solamente en lo que respecta al número de parejas sexuales y edad de inicio de las relaciones sexuales como factor de riesgo de CC. Conclusión: Las adolescentes conocen sobre la transmisión del VPH; sin embargo, las conductas preventivas no se relacionan con dicho conocimiento.
Sujets)
Adolescent , Femelle , Humains , Jeune adulte , Connaissances, attitudes et pratiques en santé , Infections à papillomavirus/prévention et contrôle , Comportement sexuel , Maladies sexuellement transmissibles/prévention et contrôle , Tumeurs du col de l'utérus/prévention et contrôle , Chili , Études de cohortes , Études transversales , Tumeurs du col de l'utérus/virologieRésumé
Background: Portfolio is an innovative instrument that promotes reflection, creativity and professionalism among students. Aitn: To describe the development and validation process of a questionnaire to evalúate the use of portfolio in undergraduate medical students. Material andMethods: Focus groups with students and teachers were employed to identify aspects related with portfolio in undergraduate teaching. The Delphi technique was used to prioritize relevant aspects and construct the questionnaire. The validated questionnaire, consistingin 43 Ítems and 6factors, was appliedto 97students (response rote of99.9 percent) in2007and 100students (99.2 percent) in 2008. Each question had to be answered using a Likert scale,from 0 (completely disagree) to 4 (completely agree) The validity and reliability of the questionnaire was evaluated. Results: The questionnaire showed a high reliability (Cronbach alpha = 0.9). The mean total scores obtained in 2007 and 2008 were 106.2 ± 21.2 (61.7 percent ofthe maximal obtainable score) and 104.6 ± 34.0 (60.8 percent ofthe maximal obtainable score), respectively No significant differences were seen in the analysis by factors. Changes in portfolio during 2008 showed differences in Ítems related with organization, evaluation and regulation. Conclusions: The questionnaire is a valid and highly reliable instrument, measuringperceptions about the portfolio by undergraduate medical students. The students perceived an improvement in their creativity and professionalism as one ofthe strengths of portfolio. The weaknesses identified during the implementation process helped us to focus changes in organization and evaluation to improve the portfolio as a dynamic process.
Sujets)
Humains , Créativité , Enseignement médical premier cycle/méthodes , Compétence professionnelle , Enquêtes et questionnaires/normes , Étudiant médecine/psychologie , Enseignement médical premier cycle/normes , Analyse statistique factorielle , Groupes de discussion , PerceptionRésumé
Background: The Dundee Ready Education Environment Measure (DREEM) is the most valid and reliable instrument to measure the educational environment (EE) in undergraduate medical education. Aim: To evaluate the EE perceived by undergraduate medical students in Chile, using a Spanish version of the DREEM questionnaire. Material and Methods: The DREEM was applied during 2008 in third, fourth and ffith undergraduate years of six medical schools. The individual results were calculated and means of both global and individual domain scores of the DREEM were compared, by year, gender and between different Schools. Results: One thousand ninety two students (77 percent of the total universe of students), answered the questionnaire. The mean score of the six Schools was 113.9. The domains of Perception of Learning and Social Self-Perception obtained the lower scores, with a global outcome indicating a more positive than negative EE. Two schools obtained mean scores of 128.32 and 126.87, that were significantly higher than the global scores obtained by other schools. No relevant differences by years or gender were observed. Conclusions: There is a signifiicant variability between the six schools evaluated and two of these obtained signifiicantly better scores than the rest. The identified positive and negative areas will orient the actions to improve the EE for undergraduate medical students.