Addressing Challenges and Opportunities: A Critical Assessment of RFID Adoption in Agriculture

This review paper critically assesses the challenges and opportunities associated with Radio Frequency Identification (RFID) adoption in agriculture. RFID technology has the potential to revolutionize agricultural processes, offering benefits such as improved supply chain management, enhanced livestock tracking, and data-driven decision-making. However, its implementation also faces various obstacles, including technical, economic, and integration challenges. Through an in-depth analysis, this review explores the socio-economic and environmental implications of RFID adoption, considering its impact on labor dynamics, job displacement, rural communities, energy consumption, and waste generation. The paper concludes with insights into the future prospects of RFID integration in agriculture and provides strategic recommendations for overcoming challenges and ensuring responsible adoption.

The Key Benefits and Application of Nanotechnology in Agriculture

The science of controlling materials at the nanoscale is known as nanotechnology. Working with the smallest particles conceivable gives rise to aspirations for increasing agricultural production by running into issues that can't be solved traditionally. In the management aspects, attempts are made to restore soil fertility by releasing fixed nutrients, as well as to boost the efficacy of applied fertilizer with the aid of nano clays and zeolites. With the aid of nano biosensors and satellite systems, the input requirements for crops are determined in controlled environments for agriculture and precision farming based on needs, and the necessary quantities are given at the appropriate times and locations. To combat the issues of managing perennial weeds and depleting the weed seed bank, nano herbicides are being developed. By using targeted delivery, slow/controlled release, and conditional release mechanisms, nanostructured formulations could more accurately time the release of their active ingredients in response to biological needs and environmental cues. According to studies, using nano fertilizers improves the efficiency with which nutrients are used, lessens soil toxicity, reduces the frequency of treatment, and minimizes any potential side effects from overdosing. Because of this, nanotechnology, especially in underdeveloped nations, has tremendous potential for attaining sustainable agriculture. To increase agricultural productivity, new technologies are frequently used in agriculture. Employing nanoparticles in agriculture is known as "nanoagriculture," and these particles will have positive effects on crops.

Correlation and Path Coefficient Analysis for Yield and Its Attributing Traits in Wheat (Triticum aestivum L.) Genotypes

The present investigation conducted on 80 accessions of wheat during 2018-19 at Main Experiment Station (MES) of A.N.D. University of Agriculture and Technology, Kumarganj, Ayodhya (U.P.) to evaluate character association and genetic divergence for the identification of most diverse and promising genotypes. The experiment was laid out in Augmented Block Design. The observations were recorded on various morphological and physiological characters. The traits thousand-grain weight, biological yield per plant, peduncle length, spike length and harvest index revealed direct effect and positive correlation therefore, these traits should be selected in future for yield improvement of wheat.

Study of maternal near miss as an indicator of quality of obstetrics care in tertiary care centre: a prospective study

Background: Maternal near miss is said to have occurred when women presented with life threatening complication during pregnancy, childbirth and within 42 days after delivery, but survive by chance or good institutional care. For identifying near miss cases five factor scoring system was used. In 2009 WHO working group has standardized the criteria for these cases.Methods: The study was a descriptive study done for the period of 18 months between 1st June 2021 to 31st December 2022 conducted in the department of Obstetrics and Gynecology at Bundelkhand Medical College Sagar, Madhya Pradesh, India, which is a tertiary care centre. For each cases of near miss, data were collected on demographic characteristics including gestational age at the time of sustaining the near morbidity, nature of obstetric complications, presence of organ dysfunction/failure, ICU admission and timing of near miss event with respect to admission.Results: A total numbers of 12252 live births were, 28 maternal deaths and 372 MNM cases were reported during the study period. Incidence of MNM was 30.3 %. In present study mortality index is 0.07. Maternal near miss to mortality ratio is 13.2:1. Hypertensive disorder of pregnancy 44.4% were most common cause of MNM followed by severe anemia 23% cases.Conclusions: Critical analysis of MNM cases will help us in identifying the deficiencies in obstetric care. Maternal mortality and morbidity can be reduced if timely and effective care can be given to women experiencing acute pregnancy related complications .There is need for validation of MNM criteria at peripheral level which will enable them in early identification and timely referral of such cases to tertiary centers.

A STUDY OF HEMATOLOGICAL AND BIOCHEMICAL PARAMETERS IN ASSESSING SEVERITY IN COVID-19 PATIENTS

Background: The severity of COVID-19 could be evaluated by examining several blood parameters mainly white blood cell (WBC) count, granulocytes, platelet, and novel hemocytometric markers neutrophils to lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR),lymphocyte to monocyte ratio (LMR) and biochemical parameters such as CRP,D-dimer,Serum ferritin, LFT, KFT etc. The present study has been carried out Methods and Material: on 100 RTPCR conrmed covid-19 patients over a period of one year from July 2021 to June 2022. Clinical features, investigations, and history of associated risk factors were extracted from case records.Samples were processed in Medonic M series ve part haematology analyzer.SELECTRA PRO M and ARCHITECT plus machine was used for LDH, AST, ALT,C- reactive protein (CRP),Serum creatinine and serum urea.Samples for electrolytes were processed in INNOLYTE MACHINE. The sample for D-dimer and PT INR were processed in STA SETELLITE Max haemostasis analyser. Samples for procalcitonin were processed in CARDIAMARKER HIA-1200 machine.Chi squre test was used for analyzing signicant correlation among different parameters and covid-19 severity.P value<0.05 was dened as statistically signicant for all statistical test. Statistical analysis used: Results:Retrospective observational study Among 100 RTPCR conrmed cases,40,36,20 and 4 were mild, moderate, severe and critical respectively.Total total neutrophils count signicantly raised in critical patients(p value<0.05) while absolute lymphocyte count was signicantly decreased in critical patients(p value<0.05).NLR was signicantly raised in critical patients and LMR,PLR were also signicantly related to disease severity.CRP,S.ferritin and D- dimer were signicantly raised in critical patients(p value<0.05).Besides above parameters, Serum LDH,Serum electrolytes,AST,AL,.PT-INR were also raised in critically ill patients(p value<0.05). The severity of COVID-19 can Conclusions: be identied at an early stage by following the different routine biochemical marker levels and subsequently improve prognosis.parameters

Assessment of Growth Parameters in Oats (Avena sativa L.) with Application of Nano Urea Fertilizer: A Field-based Study

This study aimed to evaluate the efficacy of Nano nitrogen on various growth parameters of oats leads to growth and yield, including plant height, plant population, number of leaves, leaf length, leaf width, and the total number of tillers per plant. During the study, growth parameters were recorded at 30 days after sowing and after the I and II cuts. Results revealed that 30 days after seeding, applying 100% recommended dose of nitrogen (RDN) through Urea and 75% RDN with 25% nitrogen through Nano-N resulted in significantly greater plant heights as compared to the rest of the treatment combinations. Similarly, these treatments also had significantly higher plant heights during the I and II cuts. The number of leaves significantly increased with the application of nitrogen through all sources, either individually or in combination, highest number of leaves was observed when 100% RDN was applied through Urea or when 75% RDN was applied combined with 25% nitrogen through Nano-N. The leaf length and width of the oats were also significantly improved by nitrogen management practices, with the maximum leaf length observed when 100% RDN was applied through Urea or when 75% RDN was applied combined with 25% nitrogen through Nano-N. Similarly, the highest leaf width was observed with the application of 100% RDN through Urea at all stages, while 75% RDN + 25% Nano-N was comparable to 100% RDN through Urea. The number of tillers per plant was significantly affected by different nitrogen management practices at 30 days after sowing and after the I and II harvests, highest number of tillers per plant was observed through the application of 100% RDN through Urea. Overall, the results show that the use of Nano nitrogen can significantly improve the growth attributing characteristics as well as yield attributes and yield of oats, particularly when combined with traditional nitrogen sources. These findings are consistent with previous research in this area.

An interpretive phenomenological analysis of hope in cancer patients: A qualitative study

Background: In positive psychology, increased recognition of the phenomenon of hope among people suffering from cancer, along with alleviating their negative mental states like anxiety, depression, and fear of death is evident and promising. The aim of the study was to explore the lived experience of hope in cancer patients. Materials: Qualitative phenomenological research approach was used. A semi-structured in-depth interview with open-ended questions was administered to explore the patient抯 hope related experiences during the journey of cancer. A purposive sampling technique was used to select a total of 10 participants for the study. The size of the sample was decided on the basis of literature for the interpretive phenomenological study. Results: Results revealed five major common themes related to hope during illness: (1) survival expectation; (2) will to live; (3) prognostic clarification; (4) positivity of health providers; and (5) recovery of other patients: A source of hopefulness. Conclusion: The lived experiences of cancer patients shows that hope is the positive expectation of survival, which is a source of motivation during their journey of illness. It also denotes goal setting behaviour. Thus, hope is the 搘ill to live� which is related to social support, positive communication with healthcare providers, and recovery of fellow patients.

Modular Operation Theatre

The Indian healthcare industry has grown dramatically in the last few years, particularly during Covid-19. The extraordinary participation of the Government, as well as advancements in technology and the digitization of healthcare services. In the Indian healthcare sector, several trends have emerged that are employing cutting-edge technology to simplify and improve the patient care experience. Looking at the future, it is quite sure that the healthcare system of the country will be under pressure to enhance the efficiency of care and quality and search for new ways to use systems, data, and distributed provider networks focused more on disease prevention and wellness. As a result, healthcare systems will require to be more integrated, while using technology to enhance the healthcare system. With emerging technology, the medical industry is demanding regular operation theatres to modular operation theaters in India. This is not without reason. Modular operation theaters have a concise design, integrated functionality, and a level of cleanliness that conventional operation theatres cannot match the standard. This is why more Hospitals and Healthcare institutions are investing in them with time.

Structure Based Virtual Screening of Rivastigmine Derivatives as Cholinesterase Inhibitors

The interaction of large protein molecules with small drug molecules is studiedthrough in silico studies. The molecular docking and other important pharmacokinetic (ADMET) propertiesof the compounds were carried out withrivastigmine and its derivatives againstprotein Bovine Serum Albumin (PDB: 4F5S) to describe their better protein-ligand interactions and binding affinities. Rivastigmineisapromising drug that is usedto treat Alzheimerdisease.But due to the increased drug resistance property, its use becomes less effective.Hence, better drugs with higher potency are needed against this Alzheimer disease. In order to design a more potent drug computationally, we have taken here 52 derivatives of Rivastigmineand were docked against protein Bovine Serum Albumin. Besides, quantum chemical parameters like HOMO-LUMO bandgap energy and other important pharmacological analysis like ADMET studies were also carried outto predictbetter drug candidature. Molecular dynamics simulation and MMPBSA binding free energy calculations were also validated. From this computational study, 14 designed compounds werefound to have better potencyagainst Alzheimer disease.

In vitro and in vivo anticancer potential and molecular targets of the new colchicine analog IIIM-067 / 中西医结合学报

OBJECTIVE@#The current study evaluated various new colchicine analogs for their anticancer activity and to study the primary mechanism of apoptosis and in vivo antitumor activity of the analogs with selective anticancer properties and minimal toxicity to normal cells.@*METHODS@#Sulforhodamine B (SRB) assay was used to screen various colchicine analogs for their in vitro cytotoxicity. The effect of N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(pyrrolidine-1-yl)5,6,7,9-tetrahydrobenzo[a] heptalene-7-yl] acetamide (IIIM-067) on clonogenicity, apoptotic induction, and invasiveness of A549 cells was determined using a clonogenic assay, scratch assay, and staining with 4',6-diamidino-2-phenylindole (DAPI) and annexin V/propidium iodide. Mitochondrial membrane potential (MMP) and reactive oxygen species (ROS) levels were observed using fluorescence microscopy. Western blot analysis was used to quantify expression of proteins involved in apoptosis, cell cycle, and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling. Pharmacokinetic and in vivo efficacy studies against Ehrlich ascites carcinoma (EAC) and Ehrlich solid tumor models were conducted using Swiss albino mice.@*RESULTS@#IIIM-067 showed potent cytotoxicity and better selectivity than all other colchicine analogs screened in this study. The selective activity of IIIM-067 toward A549 cells was higher among other cancer cell lines, with a selectivity index (SI) value of 2.28. IIIM-067 demonstrated concentration- and time-dependent cytotoxicity against A549 cells with half-maximal inhibitory concentration values of 0.207, 0.150 and 0.106 μmol/L at 24, 48 and 72 h, respectively. It also had reduced toxicity to normal cells (SI > 1) than the parent compound colchicine (SI = 1). IIIM-067 reduced the clonogenic ability of A549 cells in a dose-dependent manner. IIIM-067 enhanced ROS production from 24.6% at 0.05 μmol/L to 82.1% at 0.4 μmol/L and substantially decreased the MMP (100% in control to 5.6% at 0.4 μmol/L). The annexin V-FITC assay demonstrated 78% apoptosis at 0.4 μmol/L. IIIM-067 significantly (P < 0.5) induced the expression of various intrinsic apoptotic pathway proteins, and it differentially regulated the PI3K/AKT/mTOR signaling pathway. Furthermore, IIIM-067 exhibited remarkable in vivo anticancer activity against the murine EAC model, with tumor growth inhibition (TGI) of 67.0% at a dose of 6 mg/kg (i.p.) and a reduced mortality compared to colchicine. IIIM-067 also effectively inhibited the tumor growth in the murine solid tumor model with TGI rates of 48.10%, 55.68% and 44.00% at doses of 5 mg/kg (i.p.), 6 mg/kg (i.p.) and 7 mg/kg (p.o.), respectively.@*CONCLUSION@#IIIM-067 exhibited significant anticancer activity with reduced toxicity both in vitro and in vivo and is a promising anticancer candidate. However, further studies are required in clinical settings to fully understand its potential.

Comparative evaluation of displacement and stress distribution pattern during mandibular arch distalization with extra and inter-radicular mini-implants: a three-dimensional finite element study

ABSTRACT Objective: To compare the initial stress distribution and displacement on mandibular dentition using extra and inter-radicular mini-implants for arch distalization, by means of finite element analysis. Methods: For this study, two finite element models of the mandible were designed. The models consisted of periodontal ligament (PDL) and alveolar bone of all teeth until second molars. In the Case 1, bilateral extra-radicular buccal-shelf stainless steel mini-implants (10.0-mm length; 2.0-mm diameter) were placed between first and second permanent molars. In the Case 2, bilateral inter-radicular stainless steel mini-implants (10.0-mm length; 1.5-mm diameter) were placed between second premolar and first permanent molar. Power hook was attached between canine and first premolar at a fixed height of 8mm. In the two cases, 200g of distalization force was applied. ANSYS v. 12.1 software was used to analyze and compare von Mises stress and displacement in the mandibular dentition, PDL and bone. Results: Higher stresses were observed in mandibular dentition with the inter-radicular implant system. The amount of von Mises stress was higher for cortical bone (85.66MPa) and cancellous bone (3.64MPa) in Case 2, in comparison to cortical bone (41.93MPa) and cancellous bone (3.43MPa) in Case 1. The amount of arch distalization was higher for mandible in Case 1 (0.028mm), in comparison to Case 2 (0.026mm). Conclusion: Both systems were clinically safe, but extra-radicular implants showed more effective and controlled distalization pattern, in comparison to inter-radicular implants, in Class III malocclusion treatment.

RESUMO Objetivo: Comparar a distribuição da tensão inicial e o deslocamento na dentição inferior usando mini-implantes extra e inter-radiculares para distalização da arcada, por meio da análise de elementos finitos. Métodos: Dois modelos de elementos finitos da mandíbula foram criados, os quais consistiram de ligamento periodontal (PDL) e osso alveolar de todos os dentes até os segundos molares. No Caso 1, mini-implantes extra-radiculares de aço inoxidável (10,0 mm de comprimento; 2,0 mm de diâmetro) foram colocados bilateralmente na buccal-shelf entre o primeiro e o segundo molares permanentes. No Caso 2, mini-implantes de aço inoxidável inter-radiculares (comprimento de 10,0 mm; diâmetro de 1,5 mm) foram colocados bilateralmente entre o segundo pré-molar e o primeiro molar permanentes. Um Power hook foi preso entre o canino e o primeiro pré-molar a uma altura fixa de 8mm. Nos dois casos, foi aplicada força de distalização de 200g. O software ANSYS v. 12.1 foi usado para analisar e comparar a tensão de von Mises e o deslocamento na dentição inferior, ligamento periodontal e osso. Resultados: Maiores tensões foram observadas na dentição inferior com o sistema de implantes inter-radiculares. A quantidade de tensões de von Mises foi maior para osso cortical (85,66MPa) e osso esponjoso (3,64MPa) no Caso 2, em comparação com osso cortical (41,93MPa) e osso esponjoso (3,43MPa) no Caso 1. A quantidade de distalização da arcada inferior foi maior no Caso 1 (0,028 mm), em comparação com o Caso 2 (0,026 mm). Conclusão: Ambos os sistemas foram clinicamente seguros, mas os implantes extra-radiculares mostraram um padrão de distalização mais eficaz e controlado, em comparação com os implantes inter-radiculares, para tratamento da má oclusão de Classe III.

Assessment of anti-inflammatory activity of Tridax procumbens in wistar rats

Background: Tridax procumbens Linn. is a spreading herb found throughout India. Tridax procumbens is known for several potential therapeutic effects like antiviral, antioxidant, anti-infective, wound healing, insecticidal and anti- inflammatory, hepatoprotective, and antidiabetic. Novel therapies for inflammation are essential to overcome the adverse effects of existing anti-inflammatory drugs. Thus, this study was designed to evaluate anti-inflammatory activity in the experimental animal. Objective: To evaluate anti-inflammatory efficacy in experimental animal Materials and Methods: Tridax procumbens plant leaves were taken for the study. The Plant extraction was prepared by using the Soxhlet apparatus. The ethanolic extract was used as a test drug. Indomethacin and Dexamethasone were used as control drugs. Wistar rats weighing 150g to -200g were used in the study. Results: At dosages of 200 and 400 mg kg-1 , the ethanolic leaf extracts of Tridax Procumbens demonstrated substantial anti-inflammatory activity against Irish Moss-triggered inflammation. After 3 hours, 400 mgkg-1 showed a significant reduction in inflammation (48 percent), with the impact increasing after 3 hours (52 percent). The anti-inflammatory efficacy of Tridax Procumbens ethanol (EtOH) extracts was substantial and comparable to that of indomethacin (10 mg/kg). Tridax procumbens ‘s Ethanol (EtOH) leaf extract at a dose of 200 and 400 mgkg-1 , demonstrated considerable anti-inflammatory action. The average weight of granulomatous surrounding tissue in the threading was considerably smaller in the Tridax procumbens extraction group after 7 days than in the comparison group. The 400 mg kg-1 dose was shown to be the most effective of the two. the greatest reduction in the production of granuloma tissue. Tridax procumbens at doses of 200 mg/kg and 400 mg/kg resulted in substantial reductions in granuloma weights of 38.16 ± 0.04 (7.4 percent inhibition) and 34.58 ± 0.04 (16.1 percent inhibition), respectively. The lower dose of 400 mg/kg resulted in a little lesser reduction in granumola weight than the conventional medication dexamethasone (28.92 ± 0.04). (29.8 percent inhibition). Conclusion: The present study concludes that Tridax Procumbens possess anti-inflammatory effects in animal models.

Microbial Profile of Neonatal Septicemia and its Antibiogram Prevalent in a Tertiary Care Hospital of Western Odisha

Introduction : A disseminated disease with positive Blood Culture during the first month of life and encompasses various systemic infections of the newborn such as septicemia, meningitis, pneumonia, arthritis, osteomyelitis and Urinary Tract Infection is defined as Neonatal Sepsis. It is one of the leading causes of morbidity and mortality amongst neonates of developing countries. Aim : To determine the microbial profile of Blood Culture-positive Septicemia cases and study their antimicrobial susceptibility pattern. Materials and Methods : Blood Culture and C-reactive Protein (CRP) estimation were done for all 220 clinically suspected neonates. All the pure Bacterial and Candida isolates were identified using standard biochemical tests. Antimicrobial susceptibility testing was done for all bacterial isolates using the Kirby-Bauer disk diffusion method as per Clinical and Laboratory Standards Institute (CLSI) guidelines. Results : Out of 220 cases, 68.2% were culture positive. Early-onset Neonatal Septicemia (EONS) cases were 74% and Late-onset Neonatal Septicemia (LONS) 26%. The male to female ratio was 1.9:1. Bacterial cases were 66% and 34% were due to Candida. Gram-negative isolates predominated, with Klebsiella pneumonia being the most common one. In the case of Gram-positive isolates, Staphylococcus aureus was most common. The best overall sensitivity of Gram-negative isolates was to Amikacin (100%), Colistin (100%), and Imipenem (96%). Grampositive isolates reported 100% sensitivity to Vancomycin, Teicoplanin and 97.4% to Linezolid. Conclusion : Gram-negative isolates were the leading cause of Sepsis in our study. Strict antimicrobial stewardship should be implemented to prevent the emergence of multi-drug resistant strains.

FEELINGS OF ABUSE AND ITS ROLE IN THE ACCEPTANCE OF SELF AMONG FEMALE SEX WORKERS IN INDIA

Approximately three billion female sex workers are working willingly and unwillingly in India. Research has shown that female sex workers have to face stereotypes and violence from society. Due to this, they feel more depressed, yet they are not able to report everything to police personnel because of the unequal treatment because society considers them taboo. Keeping in mind, the present research aims to investigate the role of feelings of abuse and acceptance of self among female sex workers in India. A sample of 300 women (100- female sex workers, 100-working women, and 100- homemaker women) belonging to the age group of 25-40 was randomly selected from the women living in the Delhi NCR region on an availability basis. Composite Abuse Scale (Revised) Short Form and Unconditional Self-Acceptance Questionnaire were used to collect the data. After applying the Composite Abuse Scale (revised) and Unconditional Self-Acceptance Questionnaire, unconditional self-acceptance found a significant association with all dimensions of CAS among female sex workers. In this sense, working women are found higher on self-acceptance than the other two groups. Also, obtained results showed a significant difference in abuse among female sex workers, working women, and homemaker females, and all variables, female sex workers have found a significantly higher mean than homemakers and working women which stated that female sex workers are mentally, physically and sexually harassed daily which led to bad health consequences.

Solubility enhancementofcefixime trihydrate by solid dispersions using hydrotropic solubilization technique and their characterization

Abstract The aqueous solubility of cefixime trihydrate (a water insoluble drug) using different hydrotropic agents was determined and solid dispersions of cefixime trihydrate were prepared by hydrotropic solubilization technique. The drugs content were determined. The aqueous solubility of v was increased many fold in presence of sodium acetate trihydrate as hydrotropic agent. This hydrotropic agent was used to prepare solid dispersion of cefixime trihydrate. Cefixime trihydrate and sodium acetate trihydrate were accurately weighed and taken in a 200 mL beaker. Distilled water 10-15 mL was taken to dissolve hydrotropic agent using heat (48-50 °C). The drug was then added to it and magnetically stirred till whole mass get viscous. The solid dispersions of cefixime trihydrate were characterized by XRD, DSC and IR studies. DSC thermogram, XRD and Infra-Red spectra were studied. Solid dispersions, thus prepared, showed faster release of the drug as compared to pure drug and physical mixture.

Stakeholders’ Perceptions of the Implementation of a Patient-Centric Digital Health Application for Primary Healthcare in India / 대한의료정보학회지

Objectives@#Health systems are shifting from traditional methods of healthcare delivery to delivery using digital applications. This change was introduced at a primary care centre in Chandigarh, India that served a marginalised population. After establishing the digital health system, we explored stakeholders’ perceptions regarding its implementation. @*Methods@#Ethnographic methods were used to explore stakeholders’ perceptions regarding the implementation of the Integrated Health Information System for Primary Health Care (IHIS4PHC), which was developed as a patient-centric digital health application. Data were collected using focus group discussions and in-depth interviews. Participatory observations were made of day-to-day activities including outpatient visits, outreach field visits, and methods of health practice. The collected information was analysed using thematic coding. @*Results@#Healthcare workers highlighted that working with the digital health system was initially arduous, but they later realised its usefulness, as the digital system made it easier to search records and generate reports, rapidly providing evidence to make decisions. Auxiliary nurse midwives reported that recording information on computers saved time when generating reports; however, systematic and mandatory data entry made recording tedious. Staff were apprehensive about the use of computer-based data for monitoring their work performance. Patients appreciated that their previous records were now available on the computer for easy retrieval. @*Conclusions@#The usefulness of the digital health application was appreciated by various primary healthcare stakeholders. Barriers persisted due to perceived needs for flexibility in delivering healthcare services, and apprehensions continued because of increased transparency, accountability, and dependence on computers and digital technicians.

Determinants of COVID-19 Vaccination Willingness among Health Care Workers: A Quick Online Survey in India / 가정의학회지

Background@#The coronavirus disease 2019 (COVID-19) pandemic has caused a large number of deaths along with severe socio-economic effects. The vaccine is considered to be the last hope to control viral transmission. This study aimed to explore the determinants of health care workers’ (HCWs) willingness to take the COVID-19 vaccination. @*Methods@#A structured, pre-validated, and pre-tested questionnaire was administered online to 599 HCWs including physicians, residents, and nurses from different types of healthcare set-ups across India. Information was collected regarding vaccine acceptability, attitude toward vaccination, and reasons for hesitancy. The chi-square test, followed by multinomial regression analysis, was applied to determine the factors associated with HCWs’ vaccination willingness. @*Results@#It was found that 73 % (n=437) of HCWs were willing to accept the vaccines, while 10.85% (n=65) refused and 16.2% (n=96) needed more time to decide. Gender (P<0.001), occupation (P=0.040), working as front-line workers (P=0.008), vaccine manufacturing country preferences (P<0.001), and perceived risk of catching COVID-19 in the next 6 months (P=0.005) had a significant association with intent to receive vaccination (the response were “yes” vs. “no” and “not sure”). The reasons for vaccine hesitancy were vaccine safety and efficacy concerns, antivaccine attitude and beliefs, personal choice, and not wanting to take a vaccine before others. @*Conclusion@#The majority of HCWs agreed to take COVID-19 vaccines once available. Nevertheless, providing support to manage evolving vaccine environments will help change the perception of HCWs who refuse or are reluctant to take the vaccines.

Family Members’ Satisfaction Levels : Impact Of An Intensive Care Unit Information Leaflet With Verbal Information Compared To Conventional Verbal Information

@#Introduction: Patients admitted to the Intensive Care Unit (ICU) experience intense physical stress. Family members of these patients also experience stress during the admission. Therefore, it is an important task of the ICU staff to provide the family members with appropriate and clear information. There are many methods to do this. This study aimed to compare the impact of two methods of information sharing on the satisfaction levels among families of ICU patients. The novel method being introduced and investigated was a locally designed information leaflet in combination with verbal explanation. This new method was compared with the traditional method of verbal explanation only. Methods: This was a randomized controlled study, conducted at the ICU of Teluk Intan Hospital. A total of 60 participants were enrolled, with 30 participants each in the intervention and control group. The Malay version of the Validated Critical Care Family Satisfaction Survey (CCFSS) was used to measure family satisfaction with the care received during their ICU admission. Results: The intervention group reported significantly higher level of satisfaction in all of the components (Assurance, Proximity, Information, Support and Comfort). Upon further examination of the results of the intervention group, the scores in the Assurance, Proximity and Comfort component were significantly higher compared to the scores in the Information and Support component. Conclusion: Integrating an information leaflet with the traditional verbal method of delivering information has proven to provide a significant difference in satisfaction levels to the family members of patients who were admitted to the ICU.

A Novel Natural Product for Bone Regeneration in Dentistry - A Review

Herbal medicine has been regarded as a safer and more natural method to promote health and alleviate illness and has gained notable popularity. Plants continue to be the primary source of new chemicals and drugs and hence play a pivotal role in the continual improvement in therapeutic medicine. India has a huge asset of indigenous plants and minerals which have been broadly used for therapeutic claim. One such plant which has immense benefits derived from it is Cissus quadrangularis [CQ] colloquially known as hadjod or pirandai. CQ is one of the most significant plants. However, practically the entirety of its parts are utilized in medicine among which seeds, stems, roots, and shoots are the most significant parts. Concentrates and powders of Cissus quadrangularis have been utilized for a long time to aid bone and tissues healing, as an antioxidant, for relieving pain & swelling, to fight against infection, as an anabolic, and also to help in weight reduction. The most important usage has been for bone regeneration and fracture healing. Numerous studies have been done to prove its pharmacological effects and to substantiate its use clinically. The aim of this review is to elaborate on CQ, its ethnopharmacology, phytochemistry and principle constituents, pharmacological actions, formulations and to review previous literature such as animal studies, in vitro studies and clinical trials to understand in detail about the applications of this plant in medicine and dentistry

Pregnancy outcome of external cephalic version in singleton pregnancy with breech presentation at term

Background: Breech delivery is associated with poor perinatal outcomes irrespective of the route of delivery. External cephalic version can be a useful tool in management of breech presentation at term by converting it to a cephalic presentation. A study was conducted to evaluate maternal and neonatal outcome of external cephalic version in singleton pregnancies with breech presentation in third trimester.Methods: A prospective observational study was carried out at a tertiary care hospital over a period of 2 years. This study included a total of 65 uncomplicated cases of breech presentation who fulfilled the inclusion criteria. External cephalic version was carried out after 36 weeks of period of gestation in primigravida and after 37 weeks in multigravida women. These patients were followed up till delivery and data was collected and analysed regarding the mode of delivery, maternal and fetal outcome.Results: External cephalic version was successful in 41 patients with a success rate of 63%. Out of them, vaginal delivery could be achieved in 31 cases (75.6%) and LSCS was done for rest of the 10 cases. The success rate was higher in multigravida ladies compared to primigravida ladies. No major procedure related adverse event was noticed in our study.Conclusions: External cephalic version is a very safe and easy procedure which can reduce the rate of cesarean delivery in singleton pregnancies with breech presentation. The results of this study are in favor of wider practice of this procedure in selected cases.