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1.
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;54: e20200319, 2021. graf
Article de Anglais | SES-SP, ColecionaSUS, LILACS | ID: biblio-1143888

RÉSUMÉ

Abstract Bee venom is a natural toxin composed of several peptides. Massive envenoming causes severe local and systemic reactions. We report two cases of severe bee envenomation, of which one was fatal. We also describe clinical characteristics and immune markers. Both victims suffered from respiratory distress, renal failure, rhabdomyolysis, and shock. They required invasive mechanical ventilation, vasoactive drugs, and renal replacement therapy. Moreover, serum levels of chemokines, cytokines, and cell-free circulating nucleic acids demonstrated an intense inflammatory process. Massive envenoming produced systemic injury in the victims, with an uncontrolled inflammatory response, and a more significant chemotactic response in the fatal case.


Sujet(s)
Animaux , Rhabdomyolyse/diagnostic , Rhabdomyolyse/étiologie , Venins d'abeille , Morsures et piqûres d'insectes/complications , Abeilles , Brésil , Marqueurs biologiques
2.
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;54: e0374-2020, 2021. tab
Article de Anglais | LILACS | ID: biblio-1155569

RÉSUMÉ

Abstract INTRODUCTION: Snakebites in the Brazilian Amazon are caused mostly by snakes from the Bothrops genus and envenomated patients may suffer from tissue complications. METHODS: This study aimed to identify risk factors for severe tissue complications (STC) in patients with Bothrops snakebite in the Amazonas state, Brazil. RESULTS: Snakebites that were classified as severe and affected female patients with comorbidities presented greater risks of developing STCs. In addition, hospitalizations of patients with STC exceeded 5 days. CONCLUSIONS: Clinical and epidemiological characteristics can prove essential for assessing the evolution of STC and clinical prognosis of patients with Bothrops snakebites.


Sujet(s)
Humains , Animaux , Femelle , Morsures de serpent/complications , Morsures de serpent/diagnostic , Morsures de serpent/épidémiologie , Bothrops , Venins de crotalidé , Serpents , Brésil/épidémiologie , Sérums antivenimeux , Facteurs de risque
3.
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;52: e20190115, 2019. tab, graf
Article de Anglais | LILACS | ID: biblio-1013309

RÉSUMÉ

Abstract Snakebites were included by the World Health Organization in their list of neglected diseases. In Latin America, most snakebites are caused by species of the Viperidae family, notably by the genus Bothrops. Bothrops atrox accounts for 90% of the cases of envenoming in the Brazilian Amazon. In this report, we present a series of three cases of snakebites that evolved with hemorrhagic stroke due to delays in the access to antivenom in the Brazilian Amazon, being fundamental for diagnosis to validate the clinical suspicion and make decisions that would improve the treatment and prognosis of the patients.


Sujet(s)
Humains , Animaux , Mâle , Femelle , Adolescent , Adulte , Sujet âgé , Jeune adulte , Morsures de serpent/complications , Accident vasculaire cérébral/étiologie , Hémorragies intracrâniennes/étiologie , Venins de crotalidé/toxicité , Morsures de serpent/traitement médicamenteux , Brésil , Sérums antivenimeux/usage thérapeutique , Bothrops
4.
Rev. Soc. Bras. Med. Trop ; Rev. Soc. Bras. Med. Trop;51(1): 80-84, Jan.-Feb. 2018. tab, graf
Article de Anglais | LILACS | ID: biblio-1041440

RÉSUMÉ

Abstract INTRODUCTION: Hymenoptera injuries are commonly caused by stinging insects. In Amazonas state, Brazil, there is no information regarding distribution, profile, and systemic manifestations associated with Hymenoptera injuries. METHODS: This study aimed to identify risk factors for systemic manifestation using the Brazilian Notifiable Diseases Surveillance System (2007 to 2015). RESULTS: Half of Hymenoptera injuries were caused by bee stings. Hymenoptera injuries were concentrated in Manaus, and 13.36% of cases displayed systemic signs. Delayed medical assistance (4 to 12 hours) presented four times more risk for systemic manifestations. CONCLUSIONS: Simple clinical observations and history of injury are critical information for prognostic improvement.


Sujet(s)
Humains , Animaux , Mâle , Femelle , Enfant , Adolescent , Adulte , Jeune adulte , Hymenoptera/classification , Morsures et piqûres d'insectes/épidémiologie , Abeilles , Brésil/épidémiologie , Facteurs de risque , Notification des maladies , Adulte d'âge moyen
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