A case of bronchus-associated lymphoid tissue (BALT) lymphoma in the patient with rheumatoid arthritis / 대한내과학회지

Bronchus-associated lymphoid tissue (BALT) lymphoma is a rare disorder and it is a characteristic subgroup of low-grade B-cell extranodal non-Hodgkin's lymphoma that is classified as marginal zone lymphoma. We report here on a patient with rheumatoid arthritis who developed BALT lymphoma. She had no pulmonary symptoms and the pulmonary nodules were incidentally detected by routine chest radiography. Chest CT showed a 2.8cm sized ill-defined focal consolidation of homogenous attenuation in the posterobasal segment of the right lower lobe. The histological diagnosis from the wedge resection specimen revealed low grade B cell lymphoma of BALT. To the best of our knowledge, this case is the first to report BALT lymphoma that developed in a Korean patient with rheumatoid arthritis. BALT lymphoma should be included in the differential diagnosis of the pulmonary nodules in patients with rheumatoid arthritis.

A comparison of Cockcroft-Gault Formula and Modification of Diet in Renal Disease Study for Estimating Glomerular Filtration Rate in Healthy Adults / 대한내과학회지

BACKGROUND: The Cockcroft-Gault (CG) and the Modification of Diet in Renal Disease study (MDRD) equations are widely used to estimate glomerular filtration rate (GFR). We performed this study to estimate the prevalence of renal dysfunction using 2 equations in a large number of healthy adults, to compare the agreement of GFR classifications by two formulae, and to know serum creatinine concentrations equivalent to renal dysfunction. METHODS: Among the adults who underwent a health screening examination from April 2002 to March 2004, 12,276 healthy adults were selected. GFRs were calculated by CG and MDRD equations and classified as or= 80 mL/min/1.73 m2. Estimated GFR of 60 years), was consistent across the two formulae, but the absolute magnitude of the prevalence of renal dysfunction was more prominent on CG. There was weak agreement between GFR classifications by MDRD and CG. Correlation coefficients between serum creatinine and estimated GFR were significantly higher in MDRD than in CG. Serum creatinine concentrations equivalent to 60 mL/min/1.73 m2 using average body weight and height in each age group were lower when subjects were older and female. CONCLUSION: This study shows high prevalence of renal dysfunction after seventh decade in both sex. There is weak agreement between GFR classifications by MDRD and CG. Moreover, serum creatinine concentration equivalent to renal dysfucntion seems to be lower when subject is older and female.

A Case of Leriche Syndrome Manifested by Anuria / 대한신장학회잡지

Leriche syndrome is an aortoiliac occlusive disease. The aortoiliac junction is the most common sites of chronic obliterative atherosclerosis. Leriche syndrome has a variety of clinical symptoms attributed to the obstruction of the infrarenal aorta. Common clinical symptoms include thigh, hip, and buttock claudication as well as erectile impotence, usually in association with diminished femoral pulses. But acute anuric renal failure as first manifestation of Leriche syndrome is very uncommon. Contrast-enhanced 3D MRA appears to be well suited for assessment of patients with suspected Leriche syndrome. We report a 75-year-old man who presents anuria as first manifestation of Leriche syndrome.

Anaphylactoid reaction to ofloxacin with cross-reactivity to other fluoroquinolones / 천식및알레르기

Fluoroquinolones are antimicrobial agents that have a broad range of activity against both gram-negative and gram-positive organisms. Anaphylactoid reactions have been sporadically reported with fluoroquinolones. There have been a few reports that describes cross-reactivity between fluoroquinolones. We experienced a case of ofloxacin-induced anaphylactoid reaction, and confirmed cross-reactivity between ofloxacin and ciprofloxacin with the oral challenge test. Cross-reactivity between fluoroquinolones may be important, and avoidance of any fluoroquinolones should be mandatory for patients with hypersensitivity reaction to one of these drugs.