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Article de Anglais | WPRIM | ID: wpr-982347

RÉSUMÉ

Exosomes are a class of extracellular vesicles with a structure of lipid bilayer-membrane. In the central nervous system (CNS), exosomes can be secreted from both neurons and glial cells. Exosomes released into the extracellular matrix can freely cross the blood-brain barrier and function as crucial carriers of cellular communication and substance exchange in the CNS. Exosomes play a key role in the pathological process of mental disorders such as schizophrenia, depression, and bipolar disorder, and they have the potential to be used as a targeted carrier of antipsychotic medications. Exosomes are likely to become a new tool in the future to aid in the early prevention, accurate diagnosis, and effective treatment for people with mental disorders.


Sujet(s)
Humains , Exosomes/physiologie , Vésicules extracellulaires/physiologie , Système nerveux central , Troubles mentaux , Barrière hémato-encéphalique
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