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Background: Contemporary society has led to the increasing use of electronic equipment that is very much responsible for the burden of electronic waste (e-waste). E-waste contains very hazardous substance that harms health and environmental conditions. There is no delicate mechanism for the management of e-waste in Lucknow city, Uttar Pradesh. This study assessed knowledge, practice, and awareness of e-waste management among residents of this city. Material and methods: The study was conducted amongst users of electronic equipment living in the Lucknow City of Uttar Pradesh. The study was a cross-sectional descriptive study. Multi-stage random sampling was done for the selection of participants for the study. A predesigned and pretested questionnaire was administered in a single setting for all phases. The total optimum sample size is 700 individuals who participated in the study. Data were entered in MS Excel 2016 and descriptive statistics such as frequencies and percentages were calculated, applying the chi-square test for association using R-4.2.1 Statistical software. Aim and objectives: To assess the knowledge, attitude and practices regarding the management of electronic waste among users of electronic equipment residing in Lucknow city. Results: Only 37% of users are aware that e-waste adversely affects health. Only 34.3% of users knew that e-waste should be given to the seller or manufacturer for recycling while rest told that it should be stored at home, sold to a scrap dealer, or disposed with normal waste. 87.3% users are not aware about e-waste govt guidelines. In the current study electronic and print media like television, radio and news paper were not found to be source of information for e-waste disposal. Conclusion: Education regarding the ill effects of e-waste is essential for people and awareness of proper disposal of e-waste is the need of the hour. Electronic and print media as well as companies producing electronic equipment should play a significant role to awaken the respondent about the disposal of e-waste
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Background: An association has been described between tuberculosis (TB) and common mental disorders. We aimed to evaluate the patterns of psychiatric morbidities in patients with pulmonary TB. Methods: This was a prospective study conducted over a period of 1 year. A total of 100 patients were recruited for the study. Baseline psychiatric morbidity was assessed after 2 weeks of diagnosis and at the end of an intensive phase (IP). Results: In the present study, 56% of patients with pulmonary TB had morbid baseline psychiatric disorders. The major depressive episode was the most common morbid psychiatric disorder (39%), followed by panic disorder (9%), generalized anxiety disorder (GAD) (6%), and agoraphobia (2%). The psychiatric morbidity dropped to 15%. Major depressive episode dropped to 13%, followed by GAD and panic disorder (1%) each at the end of an IP. Conclusion: Because of high burden of psychiatric morbidity associated with pulmonary TB, there is a need for psychiatric services to be made available to these patients.
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Introduction: For curbing Covid-19 disease, adequate knowledge, attitude, and practices of both rural and urban population for Covid-19 disease prevention is required along with busting of the associated myths. Objectives: To assess the Knowledge, Attitude and Practices of urban and rural residents of Lucknow district regarding covid-19 preventive behaviour and associated myths. Methodology: A community-based study was conducted among 420 rural and 421 urban residents of Lucknow. Multistage random sampling was done to select the study subjects. A pre-designed pretested semi-structured questionnaire was used to collect the information regarding the Knowledge, Attitude and Practices of the residents for covid19 disease causes, prevention, and treatment. Further, KAP scoring was done to compare the two groups. Results: The mean age of the rural and urban residents was 31.48 ± 12.05 and 30.93 ± 11.96 years respectively. Only 40.4 % urban and 25.5 % rural people had correct knowledge about social distancing (p<0.0001). Knowledge regarding quarantine for covid-19 disease prevention was less among the urban residents (64.6%) as compared to rural (70.5%) (p=0.035). More than one-third (37.6%) of the rural resident believed in the myth that alcohol can prevent the covid-19 disease (p=0.003). 68.8 and 70.5 percent rural and urban residents had positive attitude towards the Indian government’ efforts in curbing the disease. Majority of the urban (90%) and rural (87.6%) residents wore mask when they went out. Only one-fourth of the urban (24.7%) and rural (22.9%) had correct practices for the duration of hand washing. Conclusion: The knowledge was more among the urban people, attitude and practices were almost similar among both the rural and urban residents while myths were more observed among the rural residents.
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Waterlogging is an important abiotic factor affecting crop productivity worldwide. Black gram (Vigna mungo L.) is very sensitive to waterlogged conditions. A field experiment was conducted in randomized complete block design to evaluate three black gram genotypes for waterlogging tolerance. Stress was imposed by maintaining the water level above the soil surface for 10 days after 30 days of sowing. Different physiological parameters including chlorophyll (Chl), chlorophyll fluorescence, normalized difference vegetation index (NDVI), sugars, along with the yield per plant and thousand grain weight (TW) were recorded in control and stressed plants. Results showed that NDVI, Chl, chlorophyll fluorescence, sugars, seed yield and TW reduced significantly during stress. Stress susceptibility index (SSI) for grain yield varied from 0.32 to 2.38. Linear correlation study showed that SSI was negatively correlated with NDVI (0.43),Chl (0.68) and TW (0.42) and grain yield (0.96). NDVI and sugars were correlated to TW under stress. IC530491 and IC559933 (SSI < 0.5) were waterlogging tolerant under field conditions. The study concluded that identified black gram lines may be utilized as trait donors in breeding program.
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COVID-19 is a severe disease characterized by a multifactorial immunodeficient state in critically ill patients who have had no prior immunodeficiencies. Much of the mortality in COVID has been attributed to an unprecedented high number of secondary coinfections ranging from bacterial pneumonia to opportunistic infections such as invasive aspergillosis and mucormycosis. Case reports reporting reactivation of cytomegalovirus (CMV) infection are scanty. To the best of our knowledge, we describe one of the very few cases of a previously immunocompetent healthy individual who suffered from reactivation of CMV infection and involvement of invasive infection (CMV pneumonia and CMV colitis).
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Background: The unprecedented demands on health‑care systems due to the COVID‑19 pandemic made countries including India to switch toward alternative modes of health‑care delivery. Objectives: The aim of this study was to describe the various COVID‑related services delivered through 104 health information helpline (HIHL), located in Jharkhand during the pandemic. Methods: The de‑identified secondary data from February 2020 to December 2021 related to COVID services delivered through HIHL were analyzed. Results: There was a significant increase in the COVID call volume during the first as well as the second wave. The HIHL has been able to guide the callers on testing, home isolation and follow‑up, home‑based teleconsultation, vaccination, timely referral, and support with logistic‑related information. Conclusion: The 104 HIHL has played a critical role in sustaining health‑care delivery during the pandemic, combating the “infodemic” and guiding the general public by providing authentic information.
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Dengue is an emerging illness in India, where it is endemic in some areas and sometimes causes yearly epidemics. Each dengue outbreak starts with high death and morbidity, which has a significant socioeconomic impact. As of September 30, 2022, India had 63,280 dengue cases, according to information provided by the National Centre for Vector Borne Diseases Control. North India is most severely impacted by each outbreak. In Uttar Pradesh, the state with the most population in India, there have been 2060 confirmed cases of dengue and 1 mortality till September 2022 reported. Patients are being reported from semi-urban, rural, and urban areas. It is essential to properly monitor disease cases through disease surveillance in order to ensure prompt case management if dengue outbreak control is to be achieved. An efficient diagnostic approach for early diagnosis is urgently required to reduce the severity of the sickness, the length of the hospital stay, and clinical consequences.
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Background- HIV/AIDS is a chronic illness. Besides having serious morbidities, opportunistic infections, it also adversely affects quality of life of People Living with HIV/AIDS (QOL- PLHIV). Early and prompt initiation of antiretroviral therapy (ART) might improve quality of life of PLHIV in various domains like psychological, physical, environment level of independence, social relationship and spirituality/religion/personal beliefs. Material and methods- The study was conducted at a medical institute of North India. Patients attending ART centre of the institute for the treatment of HIV/AIDS were interviewed on WHOQOL-HIV questionnaire. Aim and objectives- To assess and compare quality of life of people living with HIV/AIDS at initiation and after 6 months of receiving antiretroviral therapy. Result- QOL-PLHIV was improved in various domains when assessed after six months of receiving ART. For physical domain mean score increased from 12.83 to 13.85, for psychological domain from 12.54 to 14.31, for level of independence from 12.95 to 13.21, for social relationship from 12.46 to 14.15, for environment domain from 11.98 to 13.15 and for spirituality/religion/personal belief mean score increased from 11.41 to 11.96. Respective standard deviation was decreased when compared from before initiation of ART to six months after receiving ART. Conclusion – Quality of life of people living with HIV/AIDS was improved significantly after receiving ART.
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Aim: The present study aimed to estimate the total carbon sequestration potential of a 20-years-old teak (Tectona grandis) plantation forest spread over an area of 23 ha (in Odisha under Eastern Ghats stretch) through analysis of above ground and below ground biomass carbon of trees and soil organic carbon (SOC) stock.Methodology: The sampling was carried out during May to July 2017. Random non-destructive quadrate method was used for vegetation analysis. Based on the girth, height, basal area and bio volume of trees, the above ground carbon (AGC), below ground carbon (BGC) and total carbon storage in biomass (CSB) of teak plantation forest was calculated. Similarly, soil samples were taken by a soil core sampler at different depths and based on their organic carbon, bulk density, stone and gravel contents, soil organic carbon (SOC) stocks of soil was calculated. Results: The total SOC stock and CSB of the entire teak plantation forest was 489.21 t and 6670 t, respectively, across an area of 23 ha. Taking two carbon pools into account, the total carbon sequestration (TCS) of teak plantation forest patch was 7159.21 t, which arrived to be 311.27 t ha-1 with AGC of 230.16 t ha-1 and BGC of 59.84 t ha-1 and TOC stock of 21.27 t ha-1. The highest contribution in terms of carbon storage was established by above ground carbon (74%) followed by below ground carbon (19%) and SOC (7%). Interpretation: The current study reflects that teak plantation forest has rich potential of carbon sequestration not only in tree biomass but also in the SOC form and this plantation can act as a potent reservoir of carbon in the Eastern Ghats of India
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Background: Diabetes mellitus (DM) is a common non-communicable disease even in a developing country like India. Diabetes in all its forms imposes unacceptably high human, social, and economic costs on countries at all income levels. Objective: The objective of this study was conducted to assess the sociodemographic and anthropometric factors influencing DM in an urban population of district Bareilly. Materials and Methods: A cross-sectional, community-based study was conducted from February 2014 to February 2015 among adults in the age group of 30 years and above residing in the area covered under the Urban Health Training Centre of Bareilly City. A simple random sampling technique was adopted to achieve the desired sample size. House to house survey was done for collecting data. Data tabulated and subjected to statistical analysis. Results: Education status more than high school level were more prone for DM and maximum frequency of DM was also found in postgraduates and the minimum occurrence of DM was found those were having education up to primary school level. Body mass index increases the proportion of DM increases. The maximum number of diabetic individuals was found in obese Class II, followed by obese Class I and pre-obese. The pervasiveness of DM and impaired fasting glucose was more in those who were having a high waist-hip ratio. Conclusion: The study showed that in spite of having health-care facilities nearby, the indiscretion of healthiness was a major concern. The higher proportion of DM patient is prominent in who is from nuclear family, having sedentary lifestyle. There is a high proportion of obesity among them.
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Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide which unfortunately has no known effective cure to date. Despite many clinical trials indicating the effectiveness of preclinical treatment, a sensitive tool for screening of AD is yet to be developed. Due to multiple similarities between ocular and the brain tissue, the eye is being explored by researchers for this purpose, with utmost attention focused on the retinal tissue. Besides visual functional impairment, neuronal degeneration and apoptosis, retinal nerve fiber degeneration, increase in the cup-to-disc ratio, and retinal vascular thinning and tortuosity are the changes observed in the retinal tissue which are related to AD. Studies have shown that targeting these changes in the retina is an effective way of reducing the degeneration of retinal neuronal tissue. Similar mechanisms of neurodegeneration have been demonstrated in the brain and the eyes of AD patients. Multiple studies are underway to investigate the potential of diagnosing AD and detection of amyloid-? (A?) levels in the retinal tissue. Since the tissues in the anterior segment of the eye are more accessible for in vivo imaging and examination, they have more potential as screening biomarkers. This article provides a concise review of available literature on the ocular biomarkers in anterior and posterior segments of the eye including the cornea, aqueous humour (AH), crystalline lens, and retina in AD. This review will also highlight the newer technological tools available for the detection of potential biomarkers in the eye for early diagnosis of AD.
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Context: Burkitt's lymphoma (BL) is one of the fastest growing malignancies. It is the most common subtype of Non-Hodgkin's lymphoma in childhood. It has three major subtypes – endemic, sporadic, and immunodeficiency-associated types. Aims: This study aims to study the clinicomorphologic features of this disease entity and to find optimal imaging technique for such cases. Setting and Design: A retrospective observational study in a tertiary care center of academic and research potential. Subjects and Methods: We are presenting three unusual cases of sporadic type of BL who presented initially as localized right iliac fossa mass mimicking as acute appendicitis. Initially, localized presentation progressed to diffuse abdominal mass lesions causing intestinal obstruction. Results: These cases had emphasized the importance of accurate diagnosis by the ultrasonography (USG) or computed tomography (CT) scan for early diagnosis so as to manage such cases simply by early appropriate medical treatment. Conclusion: In this article, we will discuss the clinical and imaging features of BL with the role of USG, CT scan and positron emission tomography/CT in the abdominopelvic imaging of pediatric patients
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Background: The purpose of the study was desired to investigate and observe the variations in the morphology ofspleen in human fetuses. The spleen is the largest secondary lymphoid organ, in the fetal stage it also performsthe role of haematopoiesis. It acts as a blood filter, and also acts as storage site for iron, erythrocytes, andplatelets.Materials and Methods: This study has been carried out on spleen of 40 formalin preserved human fetuses (19males and 21 females) of different gestational ages, in the Department of Anatomy, Government Medical College,Haldwani over a period of two years (i.e. 2014- 2016), with due regards on ethical grounds. Various grossparameters of spleen such as its location, shape, relations, notches & fissures and ligaments were observed andthe results were statistically analyzed.Results: Spleens in all the fetuses was located in the left hypochondrium. 60% of the fetal spleens were wedgeshaped. While stomach was related to the spleen in all the gestational ages, kidney and left colic flexure were notrelated to the spleen in the early age of the fetus. Liver and left adrenal gland also showed relations with the fetalspleen. Maximum number of notches was present in the superior border followed by inferior border and lateralpole. Fissures were also seen in 11 spleens.Conclusion: Knowledge about prenatal ontogenesis of the spleen will help to understand the mechanisms ofpathology in the organ and create methods of diagnosis and prevention.
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Screening and selecting bulls for desirable reproductive traits and high libido is known to improve the reproductive performance of the herd. Evaluation of sexual behaviour and semiogram is very useful in demarcating the high fertility bulls. Therefore, the purpose of the present study was to quantify the sexual behaviour in presence of male teaser in relation to semen quality in buffalo bulls. Bulls were categorized into two groups (high and low libido) on the basis of reaction time. The average duration of first licking of prepucial area was significantly (p<0.05) lower in high libido bulls as compared to low libido bulls. The average frequency and overall duration of licking of prepucial area until ejaculation in high libido buffalo bulls was significantly (p<0.05) lower as compared to low libido bulls. The average time lag to show flehmen response following sniffing and licking the prepucial area and urine of teaser male was similar (p>0.05) in high and low libido buffalo bulls. The average chin resting time were similar (p>0.05) in high and low libido buffalo bulls. Individual sperm motility (%) and viability (%) was found to be significantly higher (P<0.05) in high than the low libido bulls. Sperm abnormality (%) was significantly higher (P<0.05) in low libido bulls. Therefore, it can be concluded that breeding buffalo bulls can be demarcated for high libido based on quantification of sexual behaviour traits in relation to semen picture
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Aim: The study was carried out to assess the overall genetic variability of 60 mango (Mangifera indica) genotypes for important fruit quality and yield characteristics to select better parents for mango breeding programme. Methodology: A total of 17 variables were scored and subjected to multivariate analysis. ANOVA, descriptive statistics, cluster analysis and principal component analysis were used to investigate variability among the genotypes for the selected traits. Results: Significant phenotypic variability was observed for studied traits. Cluster analysis classified all genotypes into two major groups according to shared similarity. Principal component analysis revealed that traits like fruit weight, fruit diameter, pulp content and pulp: stone ratio contributed positively, while fruit shape index, TSS:acid ratio, stone and peel traits contributed negatively for a large proportion of the observed variability. Interpretation: Pusa Arunima, Pusa Shresth, Pusa Lalima, Mallika, Ramkela, Amrapali, Extreema, Neelum, Gulab Jamun, S.B. Alibagh, Tommy Atkins, Primor-de-Amoreira genotypes were found unique for fruit and yield attributing traits, thus making them potential donor parent for fruit weight, fruit color, fruit diameter, fruit shape, pulp and pulp: stone traits in mango hybridization programme.
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Tuberculosis (TB) remains a leading cause of death globally among infectious diseases that has killed more numbers of people than any other infectious diseases. Animal models have become the lynchpin for mimicking human infectious diseases. Research on TB could be facilitated by animal challenge models such as the guinea pig, mice, rabbit and non-human primates. No single model presents all aspects of disease pathogenesis due to considerable differences in disease resistance/susceptibility between these models. Availability of a wide range of animal strains, Mycobacterium tuberculosis strains, route of infection and doses affect the disease progression and intervention outcome. Different animal models have contributed significantly to the drug and vaccine development, identification of biomarkers, understanding of TB immunopathogenesis and host genetic influence on infection. In this review, the commonly used animal models in TB research are discussed along with their advantages and limitations.
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Rice is a staple food for humans and its demand in 2035 has been put at 852 million tons. Knowledge on genes and genome architecture helps in better understanding of growth and development mechanisms for crop improvement. Transgenic crops may offer a solution by means of higher yield and resistance to biotic and abiotic stresses. In this context, modification of Agrobacterium mediated transformation protocol for indica rice cultivar is imperative to increase transformation efficiency and reduce duration of transgenic development. Here, we developed an efficient Agrobacterium mediated transformation protocol using early scutellum derived calli of the indica rice cultivar Pusa Sugandh 2. Competency of 3, 4, 5 and 6 day old primary calli was compared with 21- day old secondary calli for Agrobacterium mediated transformation using a modified pCAMBIA 1304 harbouring GFP-GUS fusion gene driven by maize ubiquitin 1 promoter. The highest competency with stable transformation efficiency of 51% was observed for 5-6 day old primary calli. Molecular analysis confirmed stable integration of the transgene. Transgenic lines of Pusa Sugandh 2 were developed within a short period of two months using 5-6 day old primary calli.
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Background and Objectives: The deltoid ligament is a very tough and strong ligament of the ankle joint. Different studies had been done by many investigators to find out its involvement in different types of ankle trauma and diseases. There is scanty of paper in the study of morphology of deltoid ligament among Kyrgyz (Mangolion race) context, this study was carried out to fill this gap in the literature.Material and Methods: Twenty-five limbs from cadevar and 32 of fresh dead (from freezer) bodies were selected for the study. Following the dissection, the parts, borders and the attachments of the superficial fibres of the ligament was identified and their attachments were established by inspection, palpation and by slight evertion of the ankle joint. The extents of their proximal and distal attachment were also measured. Mid way between the proximal and distal attachment of the anterior and posterior border ligament point were plotted through which the breadth of the respective ligament was measured again the vernier calipers. Data were entered in Excel and SPSS and were analyzed.Results: The result showed that the longest ligament was the tibionavicular and the shortest was the tibiotalar ligament. Similarly the broadest ligament was found to be the tibiotalar and the narrowest was the tibiocalcaneal ligament. There was no significant variation found in the length, breadth and the attachment of the ligament in terms of the sex and side of the limb. The interesting result which was obtained from the correlation coefficient was that the lengths of the tibiocalcaneal and tibiotalar ligaments were found to be increased with increasing age.Conclusion: The lengthening of the tibiocalcaneal and tibiotalar ligament, increased breadth of tibiotalar ligament and increased extent of origin of the ligament in old age which was evident in this study.
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The aim of the present study was to compare the efficacy of naftopidil and tamsulosin in the management of ureteral stones. A total of 92 patients with symptomatic, single < 10 mm ureteral stone, were enrolled in a prospective study and randomized into two groups. Group 1, received 0.4 mg tamsulosin daily, whereas Group 2, received 50 mg naftopidil daily. Patients were followed –up for up to 6 weeks. The primary end point was stone expulsion rate and secondary end points were stone expulsion time , the rate of interventions such as uretero-renoscopy, ureteric stenting and extracorporeal shock wave lithotripsy and side effects. There were no significant differences between the groups with respect to age, sex, stone size and location. Stone expulsion rate were 76% and 56% in the tamsulosin and naftopidil group respectively. No significant difference in the stone expulsion time and the rate of interventions between the two groups. The finding suggest that tamsulosin is superior to naftopidil for stone expulsion therapy.