RÉSUMÉ
Serum samples from 465 subjects aged between 1 and 25 years were tested for antibody against hepatitis A virus (HAV) [anti-HAV IgG and IgM] to determine the seroprevalence of HAV antibody and do a cost-benefit analysis for decision making about vaccination against HAV among the general population of Bangladesh. A high prevalence of anti-HAV (74.8%) was observed in the study population; the whole study population was found positive for anti-HAV by the age of 25 years. On performing the cost-benefit analysis, it was found that the cost for vaccination with screening for anti-HAV was almost three times cheaper than vaccination without screening. Thus, in the present socioeconomic condition of Bangladesh, a policy based on screening for HAV antibody before vaccination is recommended.
Sujet(s)
Adolescent , Adulte , Bangladesh/épidémiologie , Enfant , Enfant d'âge préscolaire , Contrôle des maladies transmissibles/méthodes , Analyse coût-bénéfice , Femelle , Hépatite A/épidémiologie , Anticorps de l'hépatite A/sang , Vaccins anti-hépatite A/administration et posologie , Virus de l'hépatite A/immunologie , Humains , Immunoglobuline G/sang , Immunoglobuline M/sang , Nourrisson , Mâle , Dépistage de masse , Études séroépidémiologiques , Jeune adulteRÉSUMÉ
Traumatic ventricular septal defect (VSD) is a very uncommon condition, especially in association with blunt chest trauma. A healthy young adult was diagnosed as a case of VSD one week after a road-traffic accident. History and other medical records suggest it was an acquired post-traumatic VSD. Thus, all patients of blunt chest trauma deserve close cardiac evaluation.