RÉSUMÉ
Objective It aims to construct an evaluation index system for the development level of intelligent health insurance,which can serve as a reference for health insurance management departments in assessing the develop-ment level of intelligent health insurance and the implementation of health insurance informatization.Methods Key events in intelligent health insurance were identified based on event system theory and text analysis.The evaluation index system was determined through a combination of expert interviews and Delphi expert consultations.The entro-py method was used to calculate the weights of each index,followed by the assessment of the current and ideal de-velopment levels.Results A total of 16 experts were consulted.After two rounds of Delphi expert consultation,two first-level indicators and 18 second-level indicators were finally included in the system.The current development level of intelligent health insurance in China is at the intelligent development stage(2.524 points),while the ideal de-velopment level is at the intelligent improvement stage(4.073 points).The positivity coefficient of both rounds of Del-phi expert consultation was 100%,with an authority coefficient of 0.842,and the degree of expert coordination im-proved with each round.Conclusion The constructed evaluation index system exhibits high scientificity,stability,and generalizability.It can provide an effective evaluation tool for the development of intelligent health insurance in various pooled areas.
RÉSUMÉ
Taking the reform of DRG payment methods as the background,it discusses how the medical in-surance department uses information technology to achieve refined monitoring and management of medical institu-tions,so as to improve the quality and efficiency of medical services and control the unreasonable growth of medical expenses.The three stages of"precision monitoring-refined supervision-precision governance"of medical insurance DRG based on"refined theory"are proposed;taking Nanjing's"medical insurance high-speed railway"as an example,a DRG refined supervision and governance model framework is constructed,and its analysis is carried out monitoring elements and governance elements,and finally put forward implementation suggestions,including hori-zontal collaboration led by medical insurance,establishing a service and cost evaluation mechanism that combines in-ternal and external services.
RÉSUMÉ
It dified framework of health system resilience analysis.The research integrates practical elements from the case of the online pandemic material procurement and allocation hall in Nanjing,categorizing the resilience-building of local health systems via informatization into two distinct dimensions:static foundation and dynamic endowment.It conducts an in-depth examination of the logical pathways that leverage informatization to bolster resilience,and further investigates the inherent advantages and potential areas for optimization within informatization.The findings suggest that the synergistic empowerment of both static foundation and dynamic endowment effectively amplifies the risk defense capability and resilience of local health systems.
RÉSUMÉ
Information collaboration is an important realisation path to deepen the reform of the medical and health system and to promote the collaborative development and governance of the"Three Medicine"during the"14th Five-Year Plan"period.It employs the SFIC model and makes appropriate modifications to it.The analytical framework comprises six elements:"initial conditions-external environment-catalytic leadership-institutional de-sign-collaborative process-results feedback".This framework is used to dissect the current collaborative dilemma in the"Three Medicine"information collaboration and governance.Based on this analysis,an optimized path for infor-mation collaborative governance is proposed:consolidating the foundation of"Three Medicine"information collabora-tion,enhancing the catalytic leadership capability of meta-governance,optimizing the institutional design of informa-tion life-cycle governance,reshaping the information collaboration process,and focusing on the evaluation feedback mechanism.
RÉSUMÉ
Digital transformation is driving the repositioning of government work and the reshaping of public ser-vice models.It uses TOE theory combined with a technology analysis framework as a theoretical perspective and a single-case study approach to explore the operational mechanism and optimization path of health insurance gover-nance modernization.The findings show that the digital transformation of health insurance is in line with the three-stage path of"structuring the enabling mechanism-forming digital service capacity-enabling value creation".The next stage is to promote the implementation of digital coding standards,accelerate the application of technology integration,respond to the needs of the insured,improve the supporting measures for the linkage of the three health care systems,and bring into play the effectiveness of modern governance of health care.It expands the scope of government governance modernisation research and has both theoretical and practical value.
RÉSUMÉ
OBJECTIVE:To evaluate the co st-utility of bivalent human papilloma virus (HPV)vaccine for 12-year-old girls in China and provide economic evidence for health service decision makers. METHODS :The CERVIVAC model was used to simulate the population of 12-year-old girls in China for a long time until all the population entered a state of death (1 year as a cycle ). The cost and health output of the people in experimental group who received the bivalent HPV vaccine and the control group who did not receive the vaccine were calculated separately , and the economics was judged combined with willingness to pay threshold [WTP ,1 time of China ’s per capita gross domestic product (GDP)in 2019]. RESULTS :During the simulation period , the incremental cost-effectiveness ratio (ICER) of the experimental group compared with the control group was 28 660.56 yuan/QALY,which was less than WTP and had pharmacoeconomic advantages. The results of single-factor sensitivity analysis showed that the five parameters that had a greater impact on ICER were discount rate ,the proportion of HPV- 16/HPV-18-induced cervical cancer ,vaccine effective rate ,direct economic burden of early/in situ cancer each year and the direct economic burden of advanced/metastatic cancer each year. The results of probabilistic sensitivity analysis showed that the experimental group was more acceptable(74%)than the control group when using 1 time of China ’s per capita GDP in 2019 as WTP ;the experimental group had a greater cost-utility advantage when WTP was higher than 25 876 yuan/QALY. CONCLUSIONS :For the prevention of cervical cancer,the bivalent HPV vaccine for 12-year-old girls in China has more cost-utility advantages than no vaccine intervention.
RÉSUMÉ
OBJECTIVE:To provide evidence-ba sed evidence for clinical treatment and decision by evaluating efficacy ,safety and cost-effectiveness of denosumab in the treatment of giant cell tumor of bone (GCTB). METHODS :Retrieved from PubMed , the Cochrane Library ,ScienceDirect,CNKI,Wanfang database and VIP as well as health technology assessment (HTA)organi- zation websites ,HTA reports ,randomized controlled trials (RCTs),single-arm trials and retrospective studies were included about denosumab in the treatment of GCTB in the adults and adolescents with mature bone ,and their qualities were evaluated. HTA reports were analyzed with descriptive analysis qualitatively ;Meta-analysis was conducted for single-arm clinical studies and retrospective studies by using R version 3.6.0 software. RESULTS :Among 49 screened literatures ,there were 6 HTA reports ,5 single-arm trials and 3 retrospective studies .No eligible RCTs were retrieved. HTA reports of various countries generally believed that denosumab possessed good efficacy and safety ;HTA reports of France ,Austrila and other contries showed that denosumab possessed economics. For the GCTB patients who was unresectable ,denosumab would bring the clinical benefits to about 81% [95%CI(77%,86%)] of patients. The complete response rate and partial response rate was around 14%[95%CI(10%,19%)] and 51%[95%CI(32%,70%)],respectively. For the GCTB patients was resectable ,denosumab would prevent some patients from receiving surgery (35%)[95%CI(21%,49%)] or bring surgical down staging to them (40%)[95%CI(36%,45%)],the postoperative recurrence rate after experiencing the denosumab therapy was about 19%[95%CI(7%,35%)],and median relapse time was approximately 6.73 months [ 95%CI(3.92,9.55)] after receiving surgery. Main grade 3-4 or high frequercy ADR requiring treatment was back pain ,limbs pain ,hypophosphatemia and jaw osteonecrosis. CONCLUSIONS :Based on the currently available evidence,among the studies and regions covered in this study ,denosumab has favorable efficacy ,safety and cost-effectiveness in the treatment of TCTB.
RÉSUMÉ
OBJECTIVE:To provide reference for scientific decision-making of evaluation and application of clinical comprehensive value of drugs from the perspective of the public decision-making in China. METHODS :Based on relevant documents and literatures ,drug clinical comprehensive value in other countries and areas ,the core indicators of drug clinical comprehensive value evaluation in China were confirmed. The concept and evaluation methods of each indicator were evaluated , and relevant suggestions were put forward. RESULTS & CONCLUSIONS :It’s suggested that the core indicators of China ’s drug clinical comprehensive value evaluation are safety and efficacy ,economy and affordability ,accessibility and fairness adherence , suitability. The concepts of safety ,efficacy,economy,affordability and adherence indexes are clearly defined ,evaluation methods are systematic ,data sources are sufficient ,and international consensus exists in research design. There is no uniform definition of accessibility which composed of availability ,deliverability,availability,affordability and timeliness. The concept of equity is clearly defined and the evaluation method is systematic ,but the data source is insufficient. Appropriateness is evaluated by drug suitability index but there is no clear definition. Taking efficacy as an example ,efficacy includes intermediate indicators ,outcome indicators and quality of life indicators ,which are often confirmed by epidemiological research ,systematic evaluation and expert consensus. It ’s suggested that the Real World Study data should be used as much as possible when selecting or formulating the clinical comprehensive value indicators of drugs. With the help of multi-criteria decision-making analysis ,technical support should be provided by professional evaluation institutions ,and with the support of experts and researchers ,the above indicators should be empowered to form the clinical comprehensive value judgment of a drug by different public decision-making departments ,so as to decide whether to purchase ,use clinically ,or incorporate medical insurance reimbursement.
RÉSUMÉ
Objective:To explore and test a blending prospective payment that suitable for integrated care delivery system in China.Methods:Referring to Accountable Care Organization and domestic reforms,it designed a performance-based and prospective global budget payment mechanism which mainly contained strategies as medical alliance contract,prepay by DRGs and performance-based management.Through a quasi-experiment,it tested its effects on controlling the inpatient spending and continuity of care.Results:There were 38 980 cases included from inpatient claims data out of 4 towns.194 medical records came from township and county hospitals.Compared to control group,the average hospitalization rate per capita every 5 months in treated group significantly declined by 0.08%,the likelihood of using upper level hospitalization significantly declined by 0.16%,and the continuity of care significantly increased by 33.80%.Global budget system would benefit decreasing hospitalization structure and improving medical collaboration.However,the effects of new model might be underestimated by the imperfect implementation of compulsory referral system.Conclusion:The medical alliances should center on combined objectives as stimulating medical cooperation and improving on quality of care.It should make the blending prospective payment decisions on basis of information-shared grading and referral medical system and empirical evidence.
RÉSUMÉ
Objective To analyze the coordination and continuity of service delivery for hypertension patients in rural health network,so as to provide references for improving integrated service utilization.Methods Self-developed questionnaire of service coordination and continuity delivery according to the research literature at home and abroad was used as the tool,and the data was analyzed by descriptive statistics.Results 49.6% patients were accompanied by one or more diseases.About 73.0% had seeking care experience in township health centers.Patients with seeking care to two or more medical institutions accounted for 51.3%.Recommending referral institutions for patients with poor therapeutic effect by grassroots doctors were the biggest proportion with 28.4% and 68.7% respectively.The proportion that superior doctors treating patients according to the related information from subordinate institutions was less than 43.0%,the proportion that junior doctors continuing to treat referral patients according to early diagnosis and treatment information was just over 40%.Easier upward referral but harder downward referral also existed among medical settings of different levels.Conclusion The disease characteristics of rural patients increased the possibility of seeking care among vertical medical institutions,but the level of continuity and coordination service delivery was not high in this network.So all-sided service integration to rural tertiary health institutions should be strengthened.
RÉSUMÉ
Objectives:To test the effect of continuous care on rural hypertension control , we developed a com-prehensive intervention strategy and implemented a community-based quasi-experiment in Southwestern rural China.Methods:The intervention took place in Qianjiang District , Chongqing Municipality from July 2012 to June 2014.4 towns were randomly selected and categorized into 2 groups based on a comprehensive consideration of population and social development level.All the rural hypertension patients in treatment group were intervened with the Multi-institu-tional Continuous Pathway which was consisted of three parts:the Continuous Primary-Care Pathway , the Continuous Clinical Pathway and the Continuous Management Pathway.The patients in the control group served as a blank com-parison using the usual care.Difference-in-differences Model was used to test the effect of blood pressure control in treatment group.Results:853 patients were sampled and investigated using the stratified randomly sampling strategy and 712 of them had been followed up by the end of this program.The potential bias of pilot and patient selection were eliminated through control before and after the intervention.The previous blood pressure trends showed no statis-tically significant difference between groups.The systolic blood pressure in treatment group declined by 10.156 mm-Hg ( P<0.001 ) compared to control group after intervention , and the blood pressure control rate had increased by 27.6% ( P<0.001 ).Other contributing factors besides intervention were family structure , education level and med-ical service availability.Conclusion:The continuous care pathway have a significant marginal positive effect on hyper -tension control besides the national compulsory primary care , and the control rate change of blood pressure is more sen-sitive compared to blood pressure change.The potential contributing factors show that other intervention strategies could be developed to improve the rural hypertension control by adding to the social capital of rural patient , reinforcing the health education and facilitating the village transportation.