Study on the role of multiple mediating effects on scientific research creativity of nursing postgraduates / 中华医学教育探索杂志

Objective:To explore the role of multiple mediating effects on scientific research creativity of nursing postgraduates.Methods:In the study, 127 nursing postgraduates from three affliated hospitals of Chongqing Medical University were selected by convenience sampling. The investigation scale included general information questionnaire, tutor support scale, nursing scientific research self-efficacy scale, autonomy motivation scale and scientific research creativity scale. The questionnaire of nursing postgraduates was collected through the Sojump platform, and the data of 127 postgraduates were effectively collected in strict accordance with the inclusion and exclusion criteria. The difference analysis and correlation analysis were carried out by SPSS.Results:The correlation analysis showed that nursing postgraduates' scientific research self-efficacy and autonomy motivation were significantly positively correlated with tutor support and scientific research creativity ( P<0.05). Multiple linear hierarchical regression analysis showed that nursing research self-efficacy and autonomy motivation played a partial mediating role between tutor support and scientific research creativity ( P<0.05), in which the mediating role explained 13.1% and 4.2% of the variation respectively. The structural equation model further verified the role of multiple mediating effects on the scientific research creativity of nursing postgraduates. Conclusion:The scientific research creativity of nursing postgraduates is closely related to tutor support, scientific research self-efficacy and autonomy motivation. Tutors can enhance nursing postgraduates' scientific research self-efficacy and autonomy motivation by improving the level of tutor support, so as to improve the scientific research creativity of postgraduates.

Sequence analysis for a case with Para-Bombay AB blood type / 中华医学遗传学杂志

OBJECTIVE@#To explore the molecular basis for a rare case with Para-Bombay AB blood type.@*METHODS@#Serological method was used to determine the blood type of the proband. Exons 6 and 7 of the ABO gene and the coding regions of FUT1 and FUT2 genes were analyzed by direct sequencing.@*RESULTS@#Serological results showed that the proband was a Para-Bombay AB subtype. His genotype was determined as ABO*A1.02/B.01. The proband was also found to harbor c.551-552delAG and c.881-882delTT of the FUT1 gene. For his four children, there were three type B and one type A, though the expression of the H type was normal.@*CONCLUSION@#The double deletions in the coding region of the FUT1 gene probably underlay the Para-Bombay blood type in the proband. Carrier of single-strand deletions may have a normal ABO phenotype.

Effect of donor dexmedetomidine preconditioning on renal function of patients undergoing living-related kidney transplantation / 中华麻醉学杂志

Objective:To evaluate the effect of donor dexmedetomidine preconditioning on the renal function of patients undergoing living-related kidney transplantation.Methods:Sixty American Society of Anesthesiologists physical status Ⅲ-Ⅳ patients, regardless of gender, aged 20-64 yr, with body mass of 18.5-28.0 kg/m 2, undergoing living-related kidney transplantation, were selected.Sixty corresponding donors, of American Society of Anesthesiologists physical status Ⅰ or Ⅱ, regardless of gender, aged 20-64 yr, with body mass index of 18.5-28.0 kg/m 2, were selected.The patients and donors were divided into 2 groups using a random number table method: control group (group C) and dexmedetomidine group (group D), with 30 pairs in each group.Before induction of anesthesia, dexmedetomidine was intravenously infused over 10 min in a loading dose of 1 μg/kg followed by an intravenous infusion of 0.5 μg·kg -1·h -1 until the time point when the renal artery was blocked immediately in the donors of group D, while the equal volume of normal saline was given instead until the time point when the renal artery was blocked immediately in the donors of group C. In both groups, total intravenous anesthesia was applied in donors and recipients, Nacotrend values were maintained at 40-60 during operation, mean arterial pressure and heart rate were maintained within the normal range, and dopamine was intravenously infused when necessary.The warm ischemia time and cold ischemia time of donor kidneys were recorded in the two groups.Peripheral venous blood samples were collected from the donors immediately before renal artery occlusion and from the recipients before renal artery opening (T 0) and at 1, 12 and 24 h after renal artery opening (T 1-3) to determine the serum creatinine (Cr), urea nitrogen (BUN) and cysteine protease inhibitor C (CysC) concentrations.The intraoperative volume of fluid infused, urine volume and consumption of propofol, remifentanil and dopamine were recorded in the receptors of two groups. Results:There was no significant difference in the concentrations of Cr, BUN and CysC and warm ischemia time and cold ischemia time of kidneys in between the two groups of donors ( P>0.05). There was no significant difference in the consumption of propofol, remifentanil and dopamine, volume of fluid infused and urine volume during surgery between the two groups of recipients ( P>0.05). Compared with group C, the concentrations of Cr, BUN and CysC were significantly decreased in at T 1 in group D ( P<0.05). Conclusion:Donor dexmedetomidine preconditioning is helpful in improving the perioperative renal function of patients undergoing living-related kidney transplantation.

Clinical practice of day care mode at a children′s specialist hospital / 中华医院管理杂志

Day care practice at children′s specialist hospitals can improve the quality of care for children patients.The hospital adopted such means as improving the service management and regulations, the service process of day care, creating the " green channel" , and moving forward and extending the care service. Their practice proved that the day care mode can significantly shorten the waiting time for hospitalization, cut back medical costs, improve the medical experience of children and their family, and achieve all-win for " community-hospital-patient".

A cross-sectional survey on prevalence of stroke and risk factors in middle-aged and elderly people in Beijing / 中华流行病学杂志

Objective To investigate the prevalence of stroke and risk factors for stroke in middle-aged and elderly population in Beijing.Methods A population based cross sectional survey was conducted among 19 145 subjects (males:6 732;females:12 413) aged ≥40 years from 3 communities in Shijingshan district of Beijing from November 2011 to August 2012.The information of subjects' demographic characteristics,lifestyle and histories of diabetes mellitus,hypertension and dyslipidemia were collected.The oral glucose tolerance test or a standard meal test was performed.Non-fatal stroke was reported by the subjects.Blood specimen were collected for detecting fasting blood glucose,TC,TG,HDL-C,LDL-C,HbA1c and 2-h blood glucose.Results The overall prevalence of stroke was 3.3％,and the gender specific prevalence was 4.8％ in males and 2.5％ in females.The standardized prevalence based on 2010 population census data was 3.2％,2.5％ and 3.9％,respectively.The overall prevalence of smoking,overweight or obesity,hypertension,hyperglycemia and dyslipidemia was 45.2％,60.4％,52.7％,51.5％,and 64.6％ in males,respectively,and 2.2％,55.1％,42.2％,45.6％,67.4％ in females,respectively.Conclusion The prevalence of stroke was higher in males than in females in the middle aged and elderly people in Beijing.The smoking rate was significantly higher in males than in females.The prevalence of overweight or obesity,hypertension,and hyperglycemia were all higher in males than in females.

A cross-sectional survey on prevalence of stroke and risk factors in middle-aged and elderly people in Beijing / 中华流行病学杂志

Objective To investigate the prevalence of stroke and risk factors for stroke in middle-aged and elderly population in Beijing.Methods A population based cross sectional survey was conducted among 19 145 subjects (males:6 732;females:12 413) aged ≥40 years from 3 communities in Shijingshan district of Beijing from November 2011 to August 2012.The information of subjects' demographic characteristics,lifestyle and histories of diabetes mellitus,hypertension and dyslipidemia were collected.The oral glucose tolerance test or a standard meal test was performed.Non-fatal stroke was reported by the subjects.Blood specimen were collected for detecting fasting blood glucose,TC,TG,HDL-C,LDL-C,HbA1c and 2-h blood glucose.Results The overall prevalence of stroke was 3.3％,and the gender specific prevalence was 4.8％ in males and 2.5％ in females.The standardized prevalence based on 2010 population census data was 3.2％,2.5％ and 3.9％,respectively.The overall prevalence of smoking,overweight or obesity,hypertension,hyperglycemia and dyslipidemia was 45.2％,60.4％,52.7％,51.5％,and 64.6％ in males,respectively,and 2.2％,55.1％,42.2％,45.6％,67.4％ in females,respectively.Conclusion The prevalence of stroke was higher in males than in females in the middle aged and elderly people in Beijing.The smoking rate was significantly higher in males than in females.The prevalence of overweight or obesity,hypertension,and hyperglycemia were all higher in males than in females.

Compilation of union catalog of minority nationality medical documents in Yunnan Province / 中华医学图书情报杂志

After the necessity to compile n the union catalog of minority nationality medical documents in Yunnan Province was analyzed according to the scattered collection of minority nationality medical information resources and no available standard minority nationality medical documents catalog, how to compile it was discussed from the aspects of the collection and catalog organization of literature information resources, and quality control of bibliographic data, in order to construct the support system for minority nationality medical information resources.

Prevalence of stroke and metabolic disorders in the middle-aged and elderly Chinese with type 2 diabetes / 中华医学杂志(英文版)

<p><b>BACKGROUND</b>Stroke is now the most prevalent and debilitating disease affecting diabetic population in China. The study aimed to investigate the prevalence of stroke and metabolic disorders in the middle-aged and elderly Chinese with type 2 diabetes.</p><p><b>METHODS</b>A total of 4 629 subjects with type 2 diabetes (males: 1 917; females: 2 712) aged ≥ 40 years from Shijingshan district, Beijing, China from November 2011 to August 2012 were included in the study. Data on demographic information, lifestyle, history of diabetes mellitus, stroke, coronary heart disease, hypertension, and dyslipidemia were collected. The oral glucose tolerance test or a standard meal test was performed. Non-fatal stroke was reported by the subjects. The 2-tailed test was used, and P < 0.05 was regarded as statistically significant.</p><p><b>RESULTS</b>Prevalence of stroke in the subjects with type 2 diabetes was 5.5%. The prevalence of smoking, overweight or obesity, hypertension, and dyslipidemia was 41.0%, 65.8%, 67.4%, and 52.0% in males, and 2.2%, 65.5%, 69.5%, and 57.6% in females. Multivariate Logistic regression analysis showed that increased age, hypertension, diabetic duration, and overweight or obesity were positively correlated with stroke in the population with type 2 diabetes, whereas high-density lipoprotein cholesterol level was negatively correlated with stroke. After adjustment for age and gender, the odds ratio values of stroke in subjects having 1, 2 or ≥3 of 4 risk factors, including smoking, overweight or obesity, hypertension and dyslipidemia, were 2.302 (95% CI: 0.789-6.712), 4.089 (95% CI: 1.470-11.373), 6.023 (95% CI: 2.176-16.666), compared with subjects without any of the above 4 risk factors.</p><p><b>CONCLUSIONS</b>The prevalence of stroke was higher in middle-aged and elderly Chinese with type 2 diabetes than that in the general population. With the aggregation of risk factors, the prevalence of stroke increased.</p>

Application of microwave irradiation technology to the field of pharmaceutics / 药学学报

Microwaves can be directly transformed into heat inside materials because of their ability of penetrating into any substance. The degree that materials are heated depends on their dielectric properties. Materials with high dielectric loss are more easily to reach a resonant state by microwaves field, then microwaves can be absorbed efficiently. Microwave irradiation technique with the unique heating mechanisms could induce drug-polymer interaction and change the properties of dissolution. Many benefits such as improving product quality, increasing energy efficiency and reducing times can be obtained by microwaves. This paper summarized characteristics of the microwave irradiation technique, new preparation techniques and formulation process in pharmaceutical industry by microwave irradiation technology. The microwave technology provides a new clue for heating and drying in the field of pharmaceutics.

Clinical epidemiological characteristics of unintentional injuries among children / 中华创伤杂志

Objective To analyze the epidemiological characteristics of unintentional injuries among children patients at age of ≤ 14 years so as to provide scientific basis for prevention of the children injury. Methods ICD-10 coding was used to retrospectively analyze the epidemiological characteristics of the children patients with unintentional injuries at age of ≤ 14 years admitted from January to December 2009 and the factors affecting the prognosis were discussed. Results There were 3011 patients, with 1991 males (66.12%) and 1 020 females (33.88%). The patients at ages of < 1, 1-4, 5-9 and 10-14 years accounted for 8.24%, 53.30%, 27.90% and 10.56% respectively. The patients from the rural and urban areas accounted for 56.16% and 43.84% respectively. Trauma was the leading sort of injuries in four age groups, accounting for 70.56%, 62.68%, 89.64% and 87.74% respectively. Fall from height was the first cause of unintentional injuries in four age groups, with proportion for 47.58%,36.39%, 51.90% and 56.29% respectively. Muhinomial logistic regression analysis revealed that hospital stay, therapeutic mode ( operation/non-operation), inhabitancy ( urban/rural), causes of injuries and injury severity on admission were the risk factors affecting the prognosis (P < 0.05 ). The rural areas caused higher risk of disability than the urban areas ( OR = 2. 170 ,P < 0.01 ) and non-operation produced higher risk of death than operation (OR = 6.352,P < 0. 01 ). Conclusions The male patients with unintentional injury are more than the female ones, with the highest incidence rate in children at age of 1-4years. Trauma is the main kind of unintentional injury and the fall from height the leading cause of injury.The difference of the rural and urban areas indicates that correct choice of the preventive measures based oh the condition of the local area can attain effective prevention and control of the unintentional injuries.

Nursing experience for children idiopathic orthosis through brace therapy / 重庆医科大学学报

Objective:to discuss clinic effects and nuring experience of children idiopathic scoliosi(sIS)by brace therapy.Method:A total of 124 cases had been analyzed during the period from Jan 1998 to May 2001.All cases received whole evaluation and education in pretherapy with less anxiety and then underwant.consecutively observation therapy Patients'feeling and needs.Were hiphly measured,complication pravention.remedial outlines was emphasized and functional exercises were strangthered.Result:All cases were followed 2 to 4 years.Overwhelming majority's abnormalities had been corrected and achieved anticipation During adorn brace.Enhanceing education and nuring can effectively reduce complication's incidence rate.Conclusion:Due to children's pathological and physiological features.the brace therapy not only can correct idiopathic scoliosis but also can effectively control advancement of early idiopathic scoliosis.empha-sizing publicity and education as well as nursing and early prevening of various complications are highly important to enhance treatment ef-fects and raise patients's quality of life.