The Effects of Unaggregated Amyloid ? Protein(25-35) on Transient Outward Potassium Current in Rat Hippocampal CA3 Pyramidal Neurons / 医学研究杂志

Objective To investigate the effects of unaggregated amyloid ? protein(A?25～35) on transient outward potassium channel(IA) in Rat Hippocampal CA3 Pyramidal Neurons.Methods Patch-clamp technique with whole cell recording was used.Results Unaggregated A?25～35 inhibited IA in neonatal rat hippocampal CA3 pyramidal neurons and displayed a time-,concentration- and voltage-dependent manner;the dynamic characteristics of IA were influenced:shifted the steady-state activation and inactivation curves to left significantly.Conclusion These results suggest that the inhibition of unaggregated A?25-35 on transient outward potassium channel in acutely isolated hippocampal CA3 pyramidal neurons may be an important mechanism of its toxicity,which participates in pathological changes of AD.

Noninvasive monitoring technology and device for tissue blood oxygen content / 医疗卫生装备

The conventional invasive tissue blood oxygen content measurement is poor in continuity.The weakness of the signal,strong interference and random transmission of the photon in tissues make the measurement difficult.Recently,near infrared spectrum technology has been applied to tissue blood oxygen content measurement.This paper presents a hardware design method for tissue blood oxygen content measurement by near infrared spectrum technology.

Interface Technology of Ferroelectric Memory and DSP / 医疗卫生装备

Objective To expand peripheral memory of DSP by using FMl8L08.Methods Because FMl8L08 not only can be randomly read in high speed,but is non-volatile and compatible with the pins of SRAM,the interface to TMS320F2812 was designed based on FMl8L08.Results FMl8L08 is used as TMS320F2812 peripheral memory expansion,instead of traditional separate ROM and RAM design,and be applied to the 12-lead ECG development.Conclusion This scheme can predigest software and hardware design complexity,enhance the system stabilization and decrease the power consumption.

Research on 3D Reconstruction Technology Based on Medical Image / 医疗卫生装备

The method and developing progress on 3D reconstruction technology based on medical image are introduced.Because 3D reconstruction technology is applied in observing bone tissue,cavum viscera and nerve tissue in clinic medicine,clear and vivid images in three dimensions can be reconstructed for clinical diagnosis.The 3D reconstruction technology based on medicine image has great application value in the course of diagnosis and therapy.[Chinese Medical Equipment Journal,2008,29(2):34-36]