Utilization of KINDL R Scale to assess HRQOL among Pediatric Patients with Epilepsy: A Prospective Interventional Study

Epilepsy, a neurological disorder characterized by abnormal brain electrical activity leading to recurrent seizures, affects approximately 1% of the Indian population, with higher prevalence in rural (1.9%) compared to urban (0.6%) settings. This interventional study conducted at a tertiary care hospital aimed to assess HRQOL among pediatric epilepsy patients using KINDL R questionnaires. Baseline data was collected from 110 pediatric patients, with two follow-up assessments conducted after interventions were implemented post the first follow-up. HRQOL was evaluated across three age groups: 3-6 years, 7-13 years, and 14-17 years. The study enrolled 110 patients and collected baseline data. Two follow-up assessments were conducted, and interventions were provided after the first follow-up. Following the intervention, HRQOL revealed positive changes in different age groups: 3-6 years (score changed from 17.37 + 2.31 to 20.79 + 4.10), 7-13 years (score changed from 53.29 + 3.96 to 58.88 + 5.68), and 14-17 years (score changed from 63.35 + 6.18 to 74.70 + 8.10). This study concludes that positive impact of pharmacist interventions on HRQOL among pediatric epilepsy patients. The findings underscore the effectiveness of pharmacist involvement in enhancing medication management and overall well-being. Further research could explore long-term effects and optimal strategies for improving HRQOL.

Percepción parental de calidad de vida relacionada con salud oral en niños de 6 a 10 años

Introducción: La caries es una de las enfermedades crónicas que más afecta a la humanidad, los niños son un grupo de alto riesgo de presentarla. La Calidad de Vida Relacionada con Salud Oral (CVRSO) se refiere a la percepción de las condiciones bucales de uno mismo y la manera en que los factores afectados impactan el bienestar y desempeño en las actividades diarias, el desarrollo de indicadores de esta se ve limitado por el nivel cognitivo de los niños, lo que genera el P-CPQ para determinar la percepción parental. Objetivo: determinar la percepción parental de la calidad de vida relacionada con la salud bucal de los niños de 6 a 10 años. Materiales y Métodos: se realizó un estudio observacional descriptivo con componente analítico. Se llevó a cabo una encuesta a 98 padres, el P-CPQ modificado que consta de 23 preguntas que abarcan las subescalas de síntomas orales, limitaciones funcionales, bienestar emocional y bienestar social. Resultados: Relacionando los resultados del cuestionario con la presencia de caries en dientes permanentes se reportó el aumento de caries con la edad; el sexo femenino predominó entre los participantes con caries siendo el 63,8%. La puntuación media fue de 13,6 (DE=13,1). Se presentó una asociación estadísticamente significativa entre la percepción parental de CVRSO de los niños y la presencia de caries dental en dientes permanentes (p=0,004). Conclusiones: Se concluyó que la presencia de caries en dientes permanentes en niños de 6 a 10 años puede disminuir significativamente la CVRSO en las dimensiones de síntomas orales, limitaciones funcionales y bienestar social.

Introduction: Caries is one of the chronic diseases that most affects humanity; children are a high-risk group for developing it. Oral Health Related Quality of Life (OHRQL) refers to the perception of one's own oral conditions and the way in which the affected factors impact well-being and performance in daily activities. The development of indicators of this is limited by the cognitive level of the children, which led to the P-CPQ to determine parental perception. Objective: to determine the parental perception of the quality of life related to the oral health of children from 6 to 10 years old. Materials and Methods: This was a descriptive and observational study with an analytical component. A survey of 98 parents was conducted, using the modified P-CPQ which consists of 23 questions covering the subscales of oral symptoms, functional limitations, emotional well-being, and social well-being. Results: Relating the results of the questionnaire with the presence of cavities in permanent teeth, an increase in cavities with age was reported; the female sex predominated among the participants with cavities, being 63.8%. The mean score was 13.6 (SD=13.1). There was a statistically significant association between parental perception of children's OHRQL and the presence of dental caries in permanent teeth (p=0.004). Conclusions: The presence of caries in permanent teeth in children aged 6 to 10 years can significantly reduce OHRQLin the dimensions of oral symptoms, functional limitations and social well-being.

Validación del cuestionario EORTC QLQ-CR29 para evaluación de la calidad de vida relacionada a la salud de personas adultas con cáncer colorrectal en Chile

Introducción: Personas con cáncer colorrectal (CCR) pueden presentar efectos adversos, perjudicando la calidad de vida relacionada a la salud (CVRS). Objetivo: Validar el módulo QLQ CR29 para evaluación de la CVRS, en Chile. Materiales y método: Estudio transversal que incluyó 170 personas con CCR. Se analizaron la consistencia interna y validez de constructo del instrumento con test de hipótesis. Resultados: 117 personas (68,8%) fueron evaluadas antes de la cirugía y 53 (31,2%) después de la cirugía. La consistencia interna del QLQ CR29 fue α = 0,838. Fueron comprobadas las hipótesis planteadas: Los pacientes evaluados antes de la cirugía se quejaron más de "sangre/mucosidad en las heces", "dolor abdominal", "pérdida de cabello" e "hinchazón abdominal", mientras que los pacientes evaluados después presentaron más "incontinencia fecal" (p < 0,05). Antes de la cirugía, los pacientes con cáncer de recto CCR presentaron mayores valores de "frecuencia urinaria", "frecuencia de deposiciones", "dolor en las nalgas", "problemas con el gusto" y "vergüenza"; mientras que aquellos con cáncer de colon que se quejaban más de "sangre/mucosidad en las heces" (p < 0,05). Después de la cirugía, los pacientes con cáncer de recto tenían mayor "frecuencia de deposiciones", "eliminación de gases" y "vergüenza" (p = 0,004) en comparación con los con cáncer de colon (p < 0,05). Los pacientes ostomizados presentaron más "incontinencia fecal" y "vergüenza" (p < 0,001). Fueron observadas correlaciones positivas y negativas bajas entre la mayoría de las dimensiones del QLQ CR29 con las dimensiones del QLQ C30. Conclusión: La versión chilena del módulo QLQ CR29 es adecuada para evaluar la CVRS en personas con CCR.

Introduction: People with colorectal cancer (CRC) can present adverse effects, impairing the quality of life related to health (HRQoL). Objective: To validate the QLQ-CR29 module for the assessment of HRQoL, in Chile. Materials and method: Cross-sectional study that included 170 people with CRC. The internal consistency and construct validity (hypothesis tests) were analyzed. Results: 117 patients (68.8%) were evaluated before surgery and 53 (31.2%) after tumor resection. The internal consistency of the QLQCR29 was α = 0.838. The proposed hypotheses were confirmed: The patients evaluated before surgery complained more of "blood/mucus in the stool", "abdominal pain", "hair loss" and "abdominal swelling", while the patients evaluated after presented more "fecal incontinence" (p < 0.05). Before surgery, patients with rectal cancer presented higher values of "urinary frequency", "frequency of stools", "pain in the buttocks", "taste problems" and "embarrassment"; while those with colon cancer complained more of "blood/mucus in stool" (p < 0.05). After surgery, patients with CCR had higher "stool frequency", "flatus" and "embarrassment" (p = 0.004) compared with those with colon cancer (p < 0.05). Ostomized patients presented more "fecal incontinence" and "embarrassment" (p < 0.001). Low significant correlations were observed between most of the dimensions of the QLQ CR29 with the dimensions of the QLQ C30. Conclusion: The Chilean version of the QLQ CR29 module is adequate to assess HRQoL in people with CRC.

Effect of pulmonary intervention and vitamin C supplementation on respiratory health status of people exposed to air pollution at Tirupati, Chittoor district, Andhra Pradesh

Background: Air pollution is a significant issue of global concern with implications for public health. The primary objective of this study was to evaluate the impact of air pollution on the respiratory health of individuals who are exposed to air pollution in Tirupati, Chittoor District, Andhra Pradesh. Methods: The present study utilised a quantitative methodology and employed a randomised control design. A total of 300 individuals using cluster sampling method were selected for this study and divided into four groups. Three of these groups received different interventions, namely pulmonary intervention, vitamin C supplementation, and a combination of pulmonary intervention and vitamin C supplementation, the fourth group served as the control group. These groups were investigated simultaneously and their outcomes were compared. Results: A notable disparity is observed in the mean scores between the pre-test and post-test measurements in the pulmonary intervention group (t=2.06, p=0.001), vitamin C supplementation group (t=3.22, p<0.001), and the combined pulmonary intervention and vitamin C supplementation group (t=3.99, p<0.000). Conversely, the control group (t=1.21, p=0.23) did not exhibit a significant difference in the pre-test and post-test mean scores. A statistically significant difference was seen in the mean post-test scores between the experimental and control groups indicated by the derived f=3.578 and a corresponding p=0.014, which met threshold for statistical significance at the p<0.05 level. Conclusions: From the study findings it is concluded that Pulmonary intervention and vitamin C supplementation has a positive impact on respiratory health status of people exposed to air pollution.

Information Needs of Patients with Cirrhosis of the Liver and Quality of Life / Necesidades de información de los pacientes con cirrosis hepática y calidad de vida

Abstract Introduction: Patients and their caregivers' knowledge about the disease is essential in the self-care process to prevent its progression and improve quality of life. Awareness of the information needs of these patients can help design educational strategies that will enhance clinical outcomes. Objectives: To identify the information needs of patients with cirrhosis of the liver and their relationship with quality of life. Methods: A cross-sectional, observational study. We designed a questionnaire considering the information collected in focus groups and previous publications to determine the priorities of patients and health personnel regarding the educational needs of patients. To establish the relationship between educational needs and quality of life, the SF36V2 survey was conducted. The perceived need for some support services and the actual use of some of them were identified to estimate their relationship with the patient's quality of life. Results: The five needs prioritized by patients were decompensations/complications, progression/prognosis, pharmacotherapy, liver cancer, and liver transplant. There was no strong relationship between information needs and quality of life. Conclusions: The information needs of patients with cirrhosis of the liver may vary depending on the etiology, the existence of comorbidities, and other sociodemographic variables such as sex and age. There are gaps between the information needs perceived by health personnel and the needs reported by patients.

Resumen Introducción: El conocimiento que los pacientes y sus cuidadores tengan de la enfermedad es fundamental en el proceso de autocuidado para evitar la progresión de la enfermedad y mejorar la calidad de vida. Conocer las necesidades de información de estos pacientes puede ser útil para diseñar estrategias educativas que mejoren los resultados clínicos. Objetivos: Identificar las necesidades de información de los pacientes con cirrosis hepática y su relación con la calidad de vida. Métodos: Estudio observacional, de corte transversal. Se diseñó un cuestionario teniendo en cuenta la información recogida en grupos focales y en publicaciones previas para determinar la prioridad de los pacientes y del personal sanitario para las necesidades educativas de los pacientes. Para determinar la relación entre las necesidades educativas y la calidad de vida se aplicó la encuesta SF36V2. De igual manera, se determinó la necesidad percibida de algunos servicios de apoyo y la utilización real de algunos de ellos para estimar su relación con la calidad de vida de los pacientes. Resultados: Las cinco necesidades priorizadas por los pacientes fueron: descompensaciones/complicaciones, progresión/pronóstico, tratamiento farmacológico, cáncer de hígado y trasplante hepático. No se observó una relación sólida entre las necesidades de información y la calidad de vida. Conclusiones: Las necesidades de información en los pacientes con cirrosis hepática pueden variar en función de la etiología, la presencia de comorbilidades y otras variables sociodemográficas como el sexo y la edad. Existen brechas entre las necesidades de información percibidas por el personal de salud y las necesidades reportadas por los pacientes.

Clinical efficacy of periodontal endoscopy-assisted subgingival scaling and root planning and its effect on psychology and quality of life in patients with periodontitis / 口腔疾病防治

Objective@#To investigate the clinical efficacy and effects of periodontal endoscope (PE)-assisted subgingival scaling and root planning (SRP) and traditional SRP on the psychological and quality of life of patients with periodontitis.@*Methods@#This study was reviewed and approved by the Ethics Committee, and informed consent was obtained from the patients. Patients with periodontitis who were treated in the Department of Periodontology, Nanjing Stomatological Hospital, Medical School of Nanjing University from April 2018 to December 2022 with residual periodontal pockets (PD ≥ 5 mm) 6 weeks after traditional SRP treatment were enrolled, and the residual periodontal pockets were further treated with PE-assisted SRP (PE+SRP). After 6 weeks of traditional SRP treatment and 3 months of PE+SRP treatment, clinical indicators, including plaque index (PLI), probing depth (PD), clinical attachment loss (CAL) and bleeding on probing (BOP), were measured, and periodontal tissue self-awareness scale scores, oral health impact profile-14 (OHIP-14) score and dental fear scale (DFS) score were collected. Moreover, visual analog scale (VAS) scores were collected after traditional SRP and PE-assisted SRP treatments.@*Results@#Twenty-three patients with periodontitis, including 832 sites of 486 affected teeth, were included in the clinical study. Three months after PE+SRP treatment, all clinical periodontal indicators, PLI (t = 9.254, P<0.001), PD (t = 50.724, P<0.001), CAL (t = 22.407, P<0.001) and BOP (t = 9.217, P<0.001), were significantly improved. Compared with traditional SRP (VAS: 2.48 ± 1.70), the pain caused by PE+SRP (VAS: 2.57±1.80) was not significantly different (t = 0,192, P = 0.850). There was no significant difference in the scores of the periodontal tissue self-awareness scale between the two groups (t = 1.485, P = 0.152). The OHIP-14 (SRP: 12.13±7.63; PE+SRP: 10.26 ± 5.25, t = -1.589, P = 0.126) and DFS (SRP: 40.70 ± 12.63; SRP+PE: 41.57 ± 12.61, t = 0.404, P = 0.690) scores were not significantly different.@*Conclusion@#All clinical periodontal indicators were significantly improved after PE-assisted SRP treatment of residual periodontal pockets, and compared with traditional SRP, PE-assisted SRP had no negative impact on the quality of life or psychological status of patients with periodontitis. Therefore, PE+SRP can be promoted in clinical practice.

Advances on the long-term prognosis of septic shock in children / 中国小儿急救医学

The mortality rate of septic shock in children is high，and the number of cases has been increasing year by year.In recent years，the number of deaths has decreased with the development of medical technology.With the increasing number of surviving children with septic shock，the prognosis regarding these patients is gaining more attention of PICU physicians than before.The long-term sequelae of patients with septic shock，which often leads to multiple organ dysfunction and complications，severely affects the quality of children life after discharge from the hospital.Notably，the meaningful outcomes mainly include physical，mental，emotional，and social functioning.Currently，few studies focusing on quality of life in children surviving from septic shock have been reported in China.Herein，this review summarized the progress of research on the long-term prognosis of patients with septic shock.

Progress in the application of patient-reported outcomes in clinical research on lymphoma / 中国综合临床

With the increasing emphasis on the bio-psycho-social medical model, significant progress has been made in patient-reported outcomes. Now, through a comprehensive analysis and synthesis of literature within the field, this study explores the advancements in the application of patient-reported outcomes in clinical research on lymphoma. The intention is to provide valuable references for future related studies.

Analysis of health-related quality of life and its influencing factors in peritoneal dialysis patients / 安徽医科大学学报

Objective @#To employ the EQ-5D-5L questionnaire to evaluate HRQOL in patients on peritoneal dialysis ( PD) and investigate the related risk factors to provide suggestions for improving quality of life．@*Methods @# PD patients who were followed up regularly in the department of nephrology were recruited in this study． Demographic characteristics and laboratory data were collected．Exercise capacity was assessed by the 6-MWT．PHQ-9 was con- ducted to screen depression status．The EQ-5D-5L questionnaire was used to evaluate HRQOL．Multivariate linear regression analysis was used to examine the potential influencing factors of EQ-5D-5L health utility value.@*Results @#The highest health utility value of EQ-5D-5L was 1 point，while the lowest was －0. 01 points．The mean EQ-5D-5L score was (0. 92 ± 0. 15 ) ． The multivariate linear regression analyses showed that increased bilirubin level ( β = - 0. 009，P = 0. 018 ) ，increased CRP level ( β = －0. 005 ，P ＜0. 001 ) ，and increased PHQ-9 score ( β = - 0. 008，P = 0. 014) were negatively correlated with the EQ-5D-5L health utility value．Increased 6-MWD ( β = 0. 005，P = 0. 018) was positively correlated with the EQ-5D-5L health utility value．@*Conclusion @# The bilirubin and CRP levels，depression status，and exercise capacity are considered the main factors influencing HRQOL in PD patients.

Prevalence of Work Ability and its Associated Factors among Secondary School Teachers in Selangor, Malaysia

@#Introduction: Work ability is the relationship between a person’s personality, health, lifestyle, and employment-related factors. There are, however, few studies evaluating the variables linked to school teachers’ work ability. The purpose of this study was to assess school teachers’ work ability and the factors that affect it. Methods: A cross-sectional study of secondary school teachers was carried out. Sociodemographic characteristics, physical activity, body mass index, low back pain (LBP), psychological factors, work-related factors, health-related quality of life (HRQoL), and work ability were all collected through the questionnaire. The association between potential factors and job ability was investigated using ordinal logistic regression. Results were presented using odds ratios (OR) and 95 % confidence intervals (CI). Results: Of 1280, there were 1037 (81.0%) teachers who returned the questionnaire. The majority (71.9%) of the participants had moderate work ability, while 22.6% had good, and 5.5% had poor work ability. None of them were particularly had excellent work ability. The factors associated with increased work ability in the multivariable analysis were better HRQoL, namely physical (OR 1.11, 95%CI: 1.07, 1.15) and mental (OR 1.12, 95%CI: 1.06, 1.16) health and wellbeing. Conclusion: Positive associations exist between a teacher’s work ability and their physical and emotional well-being. Henceforth suggesting that these factors should be incorporated in workplace health promotion programs to maintain teachers’ work ability.

Research on Health-related Quality of Life Assessment Based on Response Shift / 中国卫生经济

Health-related quality of life is one of the important concepts for developing research and practice in medicine and health.Considering the phenomenon of response shift in relevant studies can help to accurately grasp the Quality of Life change and provide more specialized analytical and causal interpretive pathways,and improve the scientific understanding of the quality of life of different groups.Starting from the connotation analysis of health-related quality of life and response shift,it discusses the existence of response shift phenomenon and its impact on the design,implementation and specific evaluation of quality of life evaluation scale on the basis of a systematic review of its mainstream research paradigm.Then,the improvement suggestions for health-related quality of life evaluation in China are put forward from the aspects of improving the design of the quality of life scale,optimizing the scale evalua-tion process,expanding the scale evaluation group,and introducing international mainstream reaction transfer detection methods.

Health-related quality of life and associated factors among people living with HIV/AIDS in Lagos, Nigeria

Background: Although people living with HIV (PLWH) now have a longer life expectancy due to antiretroviral therapy, several factors impact their health-related quality of life (HRQoL). Understanding the dimensions and determinants of HRQoL among PLWH is crucial to developing solutions to improve their overall wellbeing.Aim: This research aimed to explore the HRQoL and its associated factors among PLWH in Lagos, Nigeria. Setting: Seven HIV testing and treatment centres in Lagos. Methods: A cross-sectional survey was conducted with 385 participants. Socio-demographic and HRQoL data were obtained using questionnaires and the Medical Outcomes Study HIV Health Survey (MOS-HIV). Logistic regression models were used to identify variables that were associated with quality of life. Results: The physical health summary and mental health summary scores measured by the MOS-HIV were 54.2 ± 5.3 and 56.3 ± 6.7, respectively. Being married, having higher levels of education, shorter duration of HIV and higher income levels were significantly associated with better HRQoL. The duration of HIV was found to have an inversely proportional influence on the quality of life of PLWH, both in physical health (χ2 = 9.477, p = 0.009) and mental health (χ2 = 11.88, p = 0.004) dimensions. Conclusion: The HRQoL of PLWH in Lagos, Nigeria was relatively low. Education, duration of HIV, marital status and income level are predictors of HRQoL. Contribution: This study is valuable for healthcare professionals and policymakers, providing them with essential information to tailor interventions and allocate resources effectively to improve the overall wellbeing of PLWH in Nigeria.

Influence of genetic polymorphisms on oral health-related quality of life after root canal treatment

Abstract To evaluate the impact of genetic polymorphisms in interleukins (IL1A rs17561, rs1304037; IL10 rs1800871; IL1RN rs9005), nitric oxide (NOS2 rs2779249, rs2897518) and suppressor of cytokine signaling (SOCS1 rs243327, rs33977706) on oral health-related quality of life (OHRQoL) of patients under-going root canal treatment (RCT). Methods: The sample consisted of 108 participants, presenting single-rooted teeth with asymptomatic periapical periodontitis. The impact of the OHRQoL was recorded using the Oral Health Impact Profile (OHIP-14) before, seven, and 30 days after RCT. Saliva samples were collected as a source of genomic DNA. Genetic polymorphisms were genotyped by Real-Time PCR using the Taqman method. Univariate and Multivariate analyses were used (p<0.05). Results: A significant difference was observed for the polymorphism rs2297518 in the NOS2 gene in functional limitation in the codominant (p=0.037) and recessive (p=0.001) models; in the physical pain (p<0.001 in both models); in psychological discomfort (p<0.001 in both models); in physical disability (p<0.001 in both models) and in psychological disability (p<0.001 in both models). Polymorphisms in the SOCS1 gene, in the recessive model, rs33977706 (p=0.045) and rs243327 (p=0.019), influenced the OHRQoL in the psychological discomfort domain. Conclusions: Polymorphisms in NOS2 and SOCS1 genes influenced the OHRQoL of patients undergoing RCT.

Resumo Avaliar o impacto de polimorfismos genéticos em interleucinas (IL1A rs17561, rs1304037; IL10 rs1800871; IL1RN rs9005), óxido nítrico (NOS2 rs2779249, rs2897518) e supressor da sinalização de citocinas (SOCS1 rs243327, rs33977706) na qualidade de vida relacionada à saúde bucal (QVRSB) de pacientes submetidos a tratamento endodôntico (TE). Métodos: A amostra foi composta por 108 participantes, que apresentavam dentes unirradiculares com lesão periapical assintomática. O impacto da QVRSB foi registrado usando o Oral Health Impact Profile (OHIP-14) antes, sete e 30 dias após o TE. Amostras de saliva foram coletadas como fonte de DNA genômico. Os polimorfismos genéticos foram genotipados por PCR em tempo real usando o método Taqman. Análises univariadas e multivariadas foram utilizadas (p<0,05). Resultados: Observou-se diferença significativa para o polimorfismo rs2297518 no gene NOS2 na limitação funcional nos modelos codominante (p=0,037) e recessivo (p=0,001); na dor física (p<0,001 em ambos os modelos); no desconforto psicológico (p<0,001 em ambos os modelos); na deficiência física (p<0,001 em ambos os modelos) e na deficiência psicológica (p<0,001 em ambos os modelos). Polimorfismos no gene SOCS1, no modelo recessivo, rs33977706 (p=0,045) e rs243327 (p=0,019), influenciaram a QVRSB no domínio desconforto psicológico. Conclusões: Polimorfismos nos genes NOS2 e SOCS1 influenciaram a QVRSB de pacientes submetidos a TE.

Epidemiology of pediatriac scoliosis in a tertiary hospital in recife-pe / Epidemiologia da escoliose pediátrica em hospital terciário em recife-pe / Epidemiología de la escoliosis pediátrica en hospital terciario en recife-pe

ABSTRACT: Objective: The present study aims to outline the epidemiological parameters of patients with scoliosis between the ages of 0 and 18 years old, who were evaluated at the Getúlio Vargas Hospital in Recife-PE. Methods: The participants completed a demographic questionnaire, followed by clinical evaluation, including Cobb angle measurement, clinical photographic registration and quality of life questionnaires. Results: The sample consisted of 103 patients, mostly females, with a mean age of 13.86 years, from the interior of the state, diagnosed with adolescent idiopathic scoliosis classified as Lenke 1. Neuromuscular and congenital scoliosis were less common. The quality-of-life questionnaire showed a significant difference in self-image perception among patients with idiopathic scoliosis, those who had a curve measuring under 50 degrees had better scores than those who had greater angles. Patients with larger curves scored lower on all questionnaire items, but there was no significant difference when compared to the other group. Conclusion: It was shown that the main epidemiological parameters in the pediatric population with scoliosis are girls, mean age 13 years, coming from the interior of the state being idiopathic scoliosis, the most common, classified as Lenke 1. Neuromuscular scoliosis was the main type of deformity following the idiopathic; cerebral palsy being the most common etiology. Level of evidence IV; Prognostic Studies Investigating the effect of a Patient characteristic on the outcome of Disease.

RESUMO: Objetivo: Traçar o perfil epidemiológico dos pacientes portadores de escoliose entre as idades de 0 até 18 anos no Hospital Getúlio Vargas em Recife-PE. Métodos: Estudo transversal em que os participantes foram submetidos a um questionário demográfico, em seguida tiveram seu perfil clínico avaliado com a medição do ângulo de Cobb, realização de fotografias clínicas e aplicação de questionários de qualidade de vida. Resultados: A amostra foi construída com 103 pacientes, em sua maioria do gênero feminino, com idade média de 13,68 anos, provenientes do interior do estado, com diagnóstico de escoliose idiopática do adolescente classificadas como Lenke 1. Escoliose neuromuscular e congênita estiveram presentes em menor número. O questionário de qualidade de vida aplicado mostrou que houve diferença significativa na percepção da autoimagem de pacientes com escoliose idiopática que tinham curvas menores que 50 graus em relação aos que tinham maior deformidade. Aqueles com curvas de maior valor angular apresentavam menor pontuação em todos os quesitos do questionário, sugerindo pior qualidade de vida, mas não houve diferença significativa. Conclusão: Conclui-se que, o perfil epidemiológico dos pacientes portadores de escoliose pediátrica é formado por meninas com escoliose idiopática, com média de idade de 13 anos, provenientes do interior do estado, tendo diagnóstico de escoliose idiopática classificada como Lenke 1. Dos demais tipos de escoliose, o mais prevalente foi a escoliose neuromuscular secundária à paralisia cerebral. Nível de Evidência IV; Estudos prognósticos - Investigação do efeito de característica de um paciente sobre o desfecho da doença.

RESUMEN: Objetivos: Describir el perfil epidemiológico de los pacientes diagnosticados con escoliosis de 0 a 18 años que son evaluados en el Hospital Getúlio Vargas en Recife-PE. Métodos: Los participantes fueron sometidos a una encuesta demográfica y luego a una evaluación clínica que incluyó la toma de fotos, la medición de ángulo de Cobb y un cuestionario de calidad de vida. Resultados: La muestra fue constituida por 103 individuos, la mayoría de género femenino, con edad media de 13,68 años, que provenían del interior del estado y que fueron diagnosticadas con escoliosis idiopática del adolescente, clasificada en Lenke 1. La escoliosis neuromuscular y congénita estuvieron presentes en un número más pequeño. El cuestionario de calidad de vida mostró que hubo una diferencia significativa en la percepción de autoimagen de los pacientes con escoliosis idiopática con curvas menores a 50 grados cuando se compararon con los que tenían curvas más grandes. Los pacientes con curvas mayores tenían menos puntos en todas las preguntas del cuestionario, pero sin diferencia significativa. Conclusión: Se concluyó que el perfil epidemiológico de los pacientes con escoliosis pediátrica era formado por niñas con escoliosis idiopática, con edad media de 13 años, que provenían del interior del estado, clasificadas como Lenke 1. De los demás tipos de escoliosis, la neuromuscular secundaria a parálisis cerebral fue la más común. Nivel de evidencia IV; Estudios pronósticos - Investigación del efecto de características de un paciente sobre el desenlace de la enfermedad.

Associations between psychological stress, discrimination, and oral health-related quality of life: the buffering effects of social support networks / Associações entre estresse psicológico, discriminação e qualidade de vida relacionada à saúde bucal: os efeitos amortecedores das redes de apoio social / Asociaciones entre estrés psicológico, discriminación y calidad de vida relacionada con la salud bucal: los efectos atenuantes de las redes de apoyo social

Stress and discrimination negatively affect quality of life, but social support may buffer their effects. This study aims: (1) to examine the associations between psychological stress, discrimination, and oral health-related quality of life (OHRQoL); and (2) to assess whether social support, stress and discrimination interact to modify their associations with OHRQoL. We used cross-sectional household-based data from a study including 396 individuals aged 14 years and over from families registered for government social benefits in a city in Southern Brazil. OHRQoL was measured with the Oral Impacts on Daily Performance (OIDP) scale; psychological stress was assessed with the Perceived Stress Scale (PSS); social support was assessed based on the number of close relatives or friends of the participant, and discrimination was assessed with a short version of the Everyday Discrimination Scale. Interactions were estimated using the relative excess of risk due to interaction (RERI). Adjusted effects were calculated with logistic regression. The prevalence of oral impacts among people with higher and lower PSS scores was 81.6% and 65.5%, respectively (p < 0.01). Social support was found to have no interactions with stress levels and discrimination. The association between social discrimination and OHRQoL (OIDP score > 0) was OR = 2.03 (95%CI: 1.23; 3.34) among people with a low level of stress, but was OR = 12.6 (95%CI: 1.31; 120.9) among those with higher levels (p = 0.09, for interaction). Individuals who reported experiencing higher levels of psychological stress and discrimination had worse OHRQoL; a synergistic effect with social support was not clear.

O estresse e a discriminação afetam negativamente a qualidade de vida, mas o apoio social pode amortecer seus efeitos. Os objetivos deste estudo são: (1) examinar as associações entre estresse psicológico, discriminação e qualidade de vida relacionada à saúde bucal (QVRSB); e (2) avaliar se apoio social, estresse e discriminação interagem para modificar suas associações com QVRSB. Os dados são de uma pesquisa transversal de base domiciliar de um estudo que incluiu 396 indivíduos com 14 anos ou mais de famílias registradas para benefícios federais em uma cidade no sul do Brasil. A QVRSB foi mensurada pelo Impactos Orais no Desempenho Diário (OIDP), enquanto o estresse psicológico foi avaliado pela Escala de Estresse Percebido (PSS). Além disso, o apoio social foi avaliado pelo número de parentes ou amigos próximos e a discriminação por meio da Escala de Discriminação Diária (EDS). As interações foram estimadas por meio do excesso relativo de risco devido à interação (RERI). Os efeitos ajustados foram calculados por meio de regressão logística. A prevalência de impactos bucais entre as pessoas com maior e menor escores de PSS foi de 81,6% e 65,5%, respectivamente (p < 0,01). O apoio social mostra interações inclusivas com níveis de estresse e discriminação. A associação entre discriminação social e QVRSB (escore OIDP > 0) foi OR = 2,03 (IC95%: 1,23; 3,34) dentre pessoas com baixo nível de estresse, mas foi de OR = 12,6 (IC95%: 1,31; 120,9) dentre aqueles com níveis mais altos (p = 0,09, para interação). Indivíduos que relataram níveis mais elevados de estresse psicológico e discriminação apresentaram pior QVRSB; o efeito sinérgico com o apoio social não foi evidente.

El estrés y la discriminación afectan negativamente a la calidad de vida, pero el apoyo social puede mitigar sus efectos. Los objetivos de este estudio son: (1) examinar las asociaciones entre el estrés psicológico, la discriminación y la calidad de vida relacionada con la salud bucal (CVRSB); y (2) evaluar si el apoyo social, el estrés y la discriminación interactúan para modificar sus asociaciones con la CVRSB. Los datos provienen de una encuesta transversal de hogares cuyo estudio incluyó a 396 individuos de 14 años o más de familias registradas en beneficios del gobierno en una ciudad del Sur de Brasil. La CVRSB se midió mediante el Impactos Orales en el Rendimiento Diario (OIDP), mientras que el estrés psicológico se evaluó mediante la Escala de Estrés Percibido (PSS). El apoyo social se basó en el número de familiares o amigos cercanos, y la discriminación en la Escala de Discriminación Cotidiana (EDS). Las interacciones se estimaron mediante el excesivo de riesgo relativo debido a la interacción (RERI). Los efectos ajustados se calcularon mediante regresión logística. La prevalencia de impactos orales entre las personas con puntajes de PSS más altas y más bajas fue del 81,6% y del 65,5%, respectivamente (p < 0,01). El apoyo social presenta interacciones inclusivas con niveles de estrés y discriminación. La asociación entre discriminación social y OHRQoL (puntuación OIDP > 0) fue OR = 2,03 (IC95%: 1,23; 3,34) entre personas con un nivel bajo de estrés, pero fue OR = 12,6 (IC95%: 1,31; 120,9) entre aquellos con niveles más altos (p = 0,09, para interacción). Las personas que informaron tener niveles más elevados de estrés psicológico y discriminación tuvieron una peor CVRSB; el efecto sinérgico con el apoyo social no estaba claro.

Health-Related quality of life by 31-item Cervantes scale in breast cancer survivors undergoing adjuvant endocrine therapy

ABSTRACT Introduction Instruments to manage adverse effects of endocrine therapy with Aromatase inhibitors (AI) may improve adherence and persistence to treatment and Health-Related Quality of Life (HRQL). The 31-item Cervantes Scale (CS-31) is an HRQL questionnaire with particularities of the perimenopausal and postmenopausal period that could be an appropriate instrument to assess HRQL in Breast Cancer (BC) survivors. Objective This study aimed to perform additional validation of the CS-31 for BC survivors undergoing adjuvant endocrine therapy. Methods This prospective study was performed at three time points named T0, T1, and T2: initial, intermediate, and final follow-up period, respectively, totaling 24 months of follow-up. At each time point, the participants completed the CS-31, Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F), and Hospital Anxiety and Depression Scale (HADS). The internal consistency, construct validity, responsiveness analyses, and known-group validity of CS-31 were evaluated. Results This study included 89 postmenopausal women diagnosed with hormone receptor-positive early BC in adjuvant endocrine therapy with AI. The internal consistency was good (Cronbach's alpha = 0.89). Construct validity received a positive rating, with 100% of results consistent with prior hypotheses. A prospective improvement in HRQL was identified for the CS-31 Global Score and FACIT-F Total Score and for most of their domains. Furthermore, women with anxiety and depression by HADS presented worse HRQL by CS-31. Conclusion The authors identified that the CS-31 seems to be appropriate for use in oncology medical routine and may help to monitor adverse effects and HRQL of BC survivors during adjuvant endocrine therapy.

The association Between Sleep Quality, Fatigue and Periodontal Status: a pilot study / La asociación entre la calidad del sueño, la fatiga y el estado periodontal: un estudio piloto

Abstract Reduced sleep duration, poor sleep quality and fatigue are related to reduced immunity and increased inflammatory markers. Due to its potential to influence inflammation, poor sleep quality and fatigue could be factors for periodontitis and quality of life. Ninety-three individuals with untreated periodontitis and thirty-one individuals with healthy gingiva were included in the study. The research involved a clinical examination and a questionnaire. Demographic information, information on oral health, oral hygiene habits, the Pittsburgh Sleep Quality Index, Jenkins Sleep Scale, Multidimensional Assessment of Fatigue Scale, and Oral Health Impact Profile-14 were included in the questionnaire. Patients were diagnosed based on the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. No statistically significant difference was revealed between sleep quality, fatigue, oral health related quality of life, and stage-grade of periodontitis (p<0.05). However, periodontitis group had higher Oral Health Impact Profile-14 scores (p<0.05). A statistically significantly lower sleep duration was observed in stage IV periodontitis group than the other groups (p<0.05). A statistically significant positive correlation was observed between the Pittsburgh Sleep Quality Index and the scores of the other questionnaires (p<0.05). The stage of periodontitis may impact sleep duration.

Resumen La reducción de la duración del sueño, la mala calidad del sueño y la fatiga están relacionados con una inmunidad reducida y un aumento de los marcadores inflamatorios. Debido a su potencial para influir en la inflamación, la mala calidad del sueño y la fatiga podrían ser factores determinantes en el desarrollo de la periodontitis e incidir en la calidad de vida. Noventa y tres personas con periodontitis no tratada, además de treinta y una personas con encía sana se incluyeron en el estudio. La investigación involucró un examen clínico y un cuestionario. En el cuestionario se incluyeron información demográfica, información sobre salud bucal, hábitos de higiene bucal, el índice de calidad del sueño de Pittsburgh, la escala de sueño de Jenkins, la escala de evaluación multidimensional de la fatiga y el perfil de impacto en la salud bucal-14. Los pacientes fueron diagnosticados en base al Taller Mundial 2017 sobre la Clasificación de Enfermedades y Condiciones Periodontales y Periimplantarias. No se revelaron diferencias estadísticamente significativas entre la calidad del sueño, la fatiga, la calidad de vida relacionada con la salud bucal y el grado de etapa de la periodontitis (p<0,05). Sin embargo, el grupo de periodontitis tuvo puntajes más altos en el Perfil de Impacto en la Salud Oral-14 (p<0.05). Se observó una duración del sueño significativamente menor desde el punto de vista estadístico en el grupo de periodontitis en estadio IV que en los otros grupos (p<0,05). Se observó una correlación positiva estadísticamente significativa entre el Índice de Calidad del Sueño de Pittsburgh y las puntuaciones de los otros cuestionarios (p<0,05). La etapa de la periodontitis puede afectar la duración del sueño.

Subjective Cognitive and Communicative Complaints and Health-Related Quality of Life in Parkinson's Disease with and without Mild Cognitive Impairment / Quejas subjetivas cognitivas y comunicativas y Calidad de Vida Relacionada con la Salud en la Enfermedad de Parkinson con y Sin Deterioro Cognitivo Leve

ABSTRACT Introduction: Mild Cognitive Impairment (MCI) is common in Parkinson's Disease (PD). Few studies have compared the Health-Related Quality of Life (HRQoL) in patients with and without MCI due to PD (PD-MCI), and its correlation to patients' subjective cognitive and communicative difficulties has not been explored. Objective: We aimed to compare HRQoL in PD-MCI and PD without MCI (PD-nMCI), and explore its possible relationship to subjective cognitive and communicative complaints. Methods: We included 29 PD-nMCI and 11 PD-MCI patients. The HRQoL was assessed with the Parkinson's Disease Questionnaire-39 (PDQ-39): its Cognition dimension was used as a measure of subjective cognitive complaints, its Communication dimension for subjective communicative complaints, and the summary index (PDQ-39 SI) as an indicator of HRQoL. Non-parametric partial correlations between the Cognition and Communication dimensions, and the adjusted PDQ-39 SI were conducted. Results: PD-MCI patients had greater subjective cognitive and communicative complaints and worse HRQoL than PD-nMCI patients. In the PD-MCI group, both subjective cognitive and communicative complaints exhibited significant direct correlations with the adjusted HRQoL scores. Conclusions: HRQoL seems to be affected in PD-MCI, and it might be influenced by greater subjective cognitive and communicative complaints. Including patient-reported outcome measures of HRQoL, and providing cognitive and speech rehabilitation, as well as psy-chotherapeutic strategies to face these deficits can enhance the patient-centred approach in PD.

RESUMEN Introducción: El deterioro cognitivo leve (DCL) es frecuente en la enfermedad de Parkinson (EP). Pocos estudios han comparado la calidad de vida relacionada con la salud (CVRS) en pacientes con DCL debido a EP (EP-DCL) sin explorar la relación entre la CVRS y las quejas subjetivas cognitivas y comunicativas de los pacientes. Objetivo: Comparar la CVRS en EP-DCL y EP sin DCL (EP-nDCL) explorando sus posibles relaciones con las quejas subjetivas cognitivas y comunicativas. Métodos: Se incluyó a 29 EP-DCL y 11 EP-nDCL. La CVRS se evaluó con el cuestionario PDQ-39: su dimensión Cognición se usó como medida de las quejas subjetivas cognitivas; su dimensión Comunicación, como medida de las quejas subjetivas comunicativas y su puntuación resumen (PDQ-39 SI), como indicador de CVRS. Se realizaron correlaciones parciales no paramétricas entre el PDQ-39 SI ajustado y las dimensiones Cognición y Comunicación. Resultados: Los pacientes EP-DCL presentaron una peor CVRS y mayores quejas subjetivas cognitivas y comunicativas. En el grupo EP-DCL, tanto las quejas subjetivas cognitivas como las comunicativas mostraron correlaciones directas significativas con la puntuación de CVRS ajustada. Conclusiones: La CVRS de los pacientes con EP-DCL parece estar afectada e influida por las quejas subjetivas en cognición y comunicación. Incluir los resultados de CVRS reportados por los pacientes, proveer rehabilitación cognitiva y del lenguaje y estrategias de psicoterapia para afrontar dicho déficit podrían mejorar el abordaje centrado en el paciente en la EP.

Calidad de vida relacionada con la salud en estudiantes de tecnicatura en enfermería / Health-related quality of life among technical nursing students / Qualidade de vida relacionada à saúde em estudantes de técnica de enfermagem

Objetivo: Analizar la calidad de vida relacionada con la salud y sus factores asociados en los estudiantes de la carrera de Tecnicatura en enfermería de una institución de educación superior no universitaria de la Ciudad Autónoma de Buenos Aires, Argentina. Metodología: Estudio descriptivo, transversal y cuantitativo. La muestra estuvo constituida por 204 estudiantes de Tecnicatura en enfermería elegidos mediante muestreo no probabilístico quienes respondieron al instrumento SF-36 durante el primer cuatrimestre del 2023. Resultados: Los encuestados tuvieron una media de edad de 29,87 años (DE: 8,41) y fueron mayormente mujeres (78,92%), solteras (79,41%), sin hijos (59,31%), de segundo año del plan de estudios de la carrera (43,14%) y del turno mañana (40,69%). Relativo al autocuidado, se halló una baja prevalencia de tabaquismo (18,14%) y alta de sedentarismo (67,16%), la mayoría concurren a consulta médica 2 veces al año (58,33%) y se realizan exámenes de sangre anuales (57,35%). Al analizar las dimensiones que componen la calidad de vida relacionada con la salud, se encontró que la Función Física fue la mejor puntuada con una media de 89,95 (DE: 13,45), mientras, Vitalidad obtuvo la valoración más baja con una media de 49,12 (DE: 17,24). Conclusiones: Con excepción de la Vitalidad, todas las dimensiones evaluadas presentaban una valoración positiva. El sexo (hombre), el año del plan de estudios (tercero), el turno (vespertino), el índice de masa corporal (normal) y la implementación de actividades de autocuidado se relacionaron positivamente con la calidad de vida.

Objective: To analyze the quality of life related to health and its associated factors in technical nursing students of a non-university higher education institution in the Autonomous City of Buenos Aires, Argentina. Methods: Descriptive, cross-sectional, and quantitative study. The sample consisted of 204 technical nursing students, selected by non-probabilistic sampling, who responded to the SF-36 instrument during the first quarter of 2023. Results: Respondents had a mean age of 29.87 years (SD: 8.41) and were predominantly female (78.92%), single (79.41%), without children (59.31%), in the second year of the career (43.14%), and working the morning shift (40.69%). Regarding self-care, a low prevalence of smoking (18.14%) and a high prevalence of sedentary lifestyle (67.16%) were found. Most of the students had medical examinations twice a year (58.33%) and had annual blood tests performed (57.35%). When analyzing the dimensions that make up health-related quality of life, it was found that physical function obtained the best evaluation, with a mean of 89.95 (SD: 13.45), while vitality received the lowest evaluation with a mean of 49.12 (SD: 17.24). Conclusions: Except for vitality, all dimensions received a positive evaluation. Gender (male), year of the career (third), shift (evening), Body Mass Index (normal), and self-care activities were positively associated with quality of life.

Objetivo: Analisar a qualidade de vida relacionada com a saúde e seus fatores associados em estudantes de técnica de enfermagem de uma instituição de ensino superior não universitária da Cidade Autónoma de Buenos Aires, Argentina. Metodologia: Estudo descritivo, transversal e quantitativo. A amostra foi composta por 204 estudantes de técnica de enfermagem escolhidos por amostragem não probabilística que responderam ao instrumento SF-36 durante o primeiro quadrimestre de 2023. Resultados: Os entrevistados tinham idade média de 29,87 anos (DP: 8,41) e eram em sua maioria do sexo feminino (78,92%), solteiros (79,41%), sem filhos (59,31%), no segundo ano do curso de enfermagem (43,14%) e no turno da manhã (40,69%). Relativamente ao autocuidado, verificou-se uma baixa prevalência de tabagismo (18,14%) e uma alta prevalência de sedentarismo (67,16%), a maioria foi ao médico duas vezes por ano (58,33%) e fez análises sanguíneas anuais (57,35%). Ao analisar as dimensões que compõem a qualidade de vida relacionada com a saúde, verificou-se que a Função Física foi a mais bem classificada com uma média de 89,95 (DP: 13,45), enquanto a Vitalidade obteve a classificação mais baixa com uma média de 49,12 (DP: 17,24). Conclusões: Com exceção da Vitalidade, todas as dimensões avaliadas foram avaliadas positivamente. O sexo (masculino), o ano curricular (terceiro ano), o turno (noturno), o índice de massa corporal (normal) e a realização de atividades de autocuidado estavam positivamente relacionados com a qualidade de vida.

Scapular kinesiotaping improves upper extremity functionality in healthy active subjects

SUMMARY OBJECTIVE: The aim of this study was to investigate the effect of scapular kinesiotaping and sham-taping applications on upper extremity functionality in healthy active subjects. METHODS: In total, 60 participants were randomly divided into two groups: scapular kinesiotaping group (n=30) and sham-taping group (n=30). While scapular kinesiotaping was applied to the kinesiotaping group, scapular rigid taping was applied to the sham-taping group. At the end of the third day of the taping application, the individuals were re-evaluated. RESULTS: Participants in the scapular kinesiotaping group showed improvement in upper extremity functionality and quality of life after taping (p<0.05). In the sham-taping group, there was no statistically significant difference after taping (p>0.05). CONCLUSION: Scapular kinesiotaping is effective in improving upper extremity functionality in healthy active subjects.