Clinical efficacy of cognitive and behavioral therapy assisted by five-tone therapy for insomnia in sub-healthy people / 中国基层医药

Objective:To investigate the clinical efficacy of cognitive and behavioral therapy assisted by five-tone therapy for insomnia in sub-healthy people based on digital polysomnography observation.Methods:The clinical data of 70 sub-healthy people with insomnia who received treatment in Wenzhou Hospital of Traditional Chinese Medicine, Zhejiang University of Traditional Chinese Medicine from June 2019 to June 2021 were retrospectively analyzed. These patients were divided into a control group and an observation group ( n = 35 per group) according to different treatment methods. The control group was treated with cognitive and behavioral therapy, while the observation group was treated with cognitive and behavioral therapy assisted by five-tone therapy. Clinical efficacy, syndrome score, sleep quality, quality of life, and digital polysomnography index levels were compared between the two groups. Results:After 4 weeks of treatment, the total effective rate in the observation group was 97% (29/35), which was significantly higher than 83% (34/35) in the control group ( χ2 = 8.77, P = 0.012). The syndrome score in the observation group was (3.26 ± 2.12) points, which was significantly lower than (6.00 ± 1.68) points in the control group ( t = 5.99, P < 0.001). The Pittsburgh Sleep Quality Index score in the observation group was (3.46 ± 2.36) points, which was significantly lower than (5.60 ± 3.35) points in the control group ( t = 3.09, P = 0.003). The WHOQOL-BREF score in the observation group was (67.00 ± 5.26) points, which was significantly higher than (61.54 ± 4.63) points in the control group ( t = 4.61, P < 0.001). Total sleep time, sleep efficiency, and sleep latency in the observation group were superior to those in the control group ( t = 4.56, 5.57, 3.96, all P < 0.05). Conclusion:Cognitive and behavioral therapy assisted by five-tone therapy can markedly reduce insomnia severity and improve the quality of life in sub-healthy people with insomnia. The evaluation of insomnia status based on digital polysomnography indicators can effectively objectively evaluate the causes of insomnia, which is of great significance for guiding clinical treatment.

Relationship between sleep duration, sleep time and brachial-ankle pulse wave velocity / 中华内分泌代谢杂志

Objective:Explore the relationship between sleep duration, sleep time and brachial-ankle pulse wave velocity(baPWV) in community population.Methods:Questionnaire, physical examination, blood tests, and baPWV detection were applied to a community based population. Finally, 3 912 subjects with complete data were included in the study. The relationship between sleep duration, time to fall asleep and PWV was evaluated with binary logistic regression analysis. Results:Being adjusted for age, sex, prevalence of diabetes, sleep condition, body mass index, blood glucose, blood pressure, dyslipidemia, ankle-brachial index, sleep duration and time to fall asleep were correlated with PWV. The risk of PWV abnormalities was increased in the≥8 h group compared to the 6-8 h group( OR=1.155, 95% CI 0.995-1.367, P=0.037). The risk of abnormalities PWV was higher in the group with sleep time after 00: 00 than in the group -23: 00( OR=1.482, 95% CI 1.008-2.179, P=0.045). Conclusion:Long sleep duration(≥8 h) and late sleep time(after 00: 00) may be associated with higher risk of atherosclerosis.

Relationship between rapid eye movement sleep and incidence of angina pectoris in different genders / 西安交通大学学报(医学版)

【Objective】 To investigate the relationship between rapid eye movement sleep (REM) and the incidence of angina pectoris (AP) in different genders. 【Methods】 We recruited 2710 participants from the Sleep Heart Health Study with an average age of (61.7±10.9)y, of whom 1 103 (40.7%) were male and 1 607(59.3%) were female. The participants were divided into grade 1 (25%) according to the percentage of REM sleep time (REM%). Complete polysomnography data and medical records were collected for all the participants. Multivariate logistic regression analysis was used to characterize the independent association between REM% and the occurrence of AP. 【Results】 REM% in the three groups varied significantly in age, body mass index (BMI), smoking, AHI, diabetes, and hypertension (P25% in women was closely related to AP (OR=1.523; 95% CI:1.132-2.051, P=0.006). 【Conclusion】 Participants with REM sleep time >25% have a significantly increased prevalence of AP in women, but not in men.

Study on the Effects of Disassembled Formulation of Xiaosuanzao Decoction on Spontaneous Motion and Sleep Time in Mice / 中国药房

OBJECTIVE:To investigate the effects of Xiaosuanzao decoction on spontaneous motion and sleep time in mice, and to study its disassembled formulation. METHODS:Seven ingredients of Xiaosuanzao decoction were selected as the influential factors, including Ziziphus jujuba, Poria cocos, Ligusticum chuanxiong, Anemarrhena asphodeloides, Glycyrrhiza uralensis, Zingiber officinale and Cortex cinnamoni. Two levels of with or without were designed for each factor,and the experiment was ar-ranged according to L8(27) orthogonal test table. The effects of Xiaosuanzao decoction and each ingredient on spontaneous motion within 2 min and sleep time induced by superthreshold dosage of pentobarbital sodium were compared by visual analysis method and analysis of variance. RESULTS:Z. jujube and A. asphodeloides were the main active ingredients of Xiaosuanzao decoction on spontaneous motion;Z. jujube was the main active ingredient of Xiaosuanzao decoction on sleep time induced by superthreshold dosage of pentobarbital sodium. CONCLUSIONS:Xiaosuanzao decoction can inhibit spontaneous motion and prolong sleep time in-duced by superthreshold dosage of pentobarbital sodium,and Z. jujube is the main ingredient of Xiaosuanzao decoction.

Sleep and Type 2 Diabetes / 수면정신생리

Adequate amount and quality of sleep are important for metabolic control in patients with type 2 diabetes. Too short or too long sleep time disrupts glycemic control in both prediabetes and type 2 diabetic patients. Circadian misalignment such as shift work is also associated with an increased risk of developing type 2 diabetes. Clinicians should pay attention to the sleep problems and circadian patterns of patients. However, the pathophysiologic mechanism of the association between sleep and diabetes is likely to be complex and bidirectional. The underlying mechanism remains poorly understood, and further research is warranted.

Association of sleep time, stress, and depression with the oral health status of Korean adolescents / 대한구강보건학회지

OBJECTIVES: This study aimed to assess the association between the stress or depression and oral health status of Korean adolescents. METHODS: The subjects were 1,180 participants of the Sixth Korea National Health and Nutrition Examination Survey (KNHANES), aged 12 to 18 years. All the collected data were analyzed by using the chi-square test, t test, analysis of variance, and multiple regression analysis with the SAS version 9.3 software. Multiple regression analysis was performed to analyze the relationship of stress or depression to oral health status, and 95% confidence intervals were computed. RESULTS: Cognitive stress and depression levels for >2 weeks correlated with permanent teeth caries index. In terms of cognitive status, oral health of "a little feeling" was poorer than that of "almost no feeling," with significant statistical difference (P<0.05). CONCLUSIONS: The present study provides further evidence to support the establishment of a school oral health clinic for adolescents and hopefully provide guidance in the planning for oral health education.

Relationship between the prevalence rate of hypertension and sleeping time in Chongqing area / 重庆医学

Objective To investigate the prevalence rate of hypertension ,overweight ,obesity and obesity/overweight ,thus to explore the relationship between hypertension and sleeping time .Methods Healthy individuals having physical examinations in Health Management Center of Southwest Hospital were randomly selected to take questionnaire and physical examination ,and then we analyzed the correction relationship of hypertension and sleeping time .Results The prevalence of overweigh ,obesity ,hyperten‐sion and perhypertension was 36 .68% ,11 .36% ,22 .14% and 33 .43% respectively .The prevalence rate of hypertension for men was 2 fold as that of women .There was a negative correlation between hypertension and sleeping time .The prevalence of stage 2 hypertension tended to U.People who sleep time less than 5 h have more risk for Isolated systolic hypertension than who sleeping 6 h .Conclusion There is a high risk of hypertension and stage 2 and stage 3 hypertention for people whose sleep time less than 5 h or more than 10 h .

Qualidade do sono em crianças hospitalizadas / Quality of sleeps in hospitalized children

Objetivo: Este estudo tem como objetivo avaliar a qualidade do sono em crianças hospitalizadas na enfermaria de um hospital público de São Paulo. Métodos: A pesquisa foi realizada no Complexo Hospitalar do Mandaqui (CHM). A amostra de conveniência foi composta por 30 crianças em idade escolar (7 a 12 anos) internadas na enfermaria pediátrica do CHM, acompanhadas pelos pais ou responsáveis durante o período noturno. Após assinarem o termo de consentimento livre e esclarecido, os pais ou responsáveis pelas crianças responderam questionários sobre hábitos do sono da criança em casa e no hospital. Foram excluídas somente as crianças com diagnóstico de doenças neurológicas crônicas. Resultados: Os distúrbios mais prevalentes nesta amostra foram o de início e manutenção do sono e de transição sono-vigília (ambos com 26,7%), seguidos pelo distúrbio respiratório do sono, com 16,7%, distúrbio do despertar e hiper-hidrose do sono (ambos com 13,3%) e sonolência excessiva diurna com 10%. Conclusão: Concluímos que os distúrbios do sono mais prevalentes nos escolares hospitalizados são distúrbio de início e manutenção do sono e distúrbio de transição sono-vigília...

Survey on Sleep Time in Korean Children / 实用儿科临床杂志

Objective To evaluate the sleep characteristics of the Korean children,and explore the measurement of improving the sleep qua-lity of minority nationality children.Methods The sleep time of 1 183 from 3 to 12 years age Korean children were investigated with questionnaire The sleep time of korean children in different ages and cities were compared.Results The mean time of total sleep time in Korean children was(10.06?1.29) h,which was decreasing with the age′s increasing.The difference in different ages groups was remarkable(Pa