Fracturas de fémur distal en población geriátrica: Evaluación de estadía hospitalaria y morbimortalidad / Distal femoral fractures in the elderly: assessment of length of stay and morbimortality

INTRODUCCION Las fracturas de fémur distal (FFD) son un problema importante de salud pública. Con el envejecimiento de la población, se espera un incremento de esta lesión en los próximos años. Objetivo Describir las complicaciones y la mortalidad de las FFD en un grupo de pacientes geriátricos. MATERIALES Y METODOS Estudio descriptivo y retrospectivo de pacientes mayores de 60 años operados por FFD, todos tratados en un mismo centro, entre 2011 y 2015, con al menos 1 año de seguimiento. Se excluyeron pacientes con ficha incompleta. Se analizaron los datos demográficos y radiológicos, las complicaciones locales y sistémicas, la estadía hospitalaria y la mortalidad. RESULTADOS En total, 16 pacientes cumplieron con los criterios de selección; tenían una mediana de edad de 73 (rango: 61 a 93) años, y 14 (87,5%) eran mujeres. La clasificación de la Asociación para el Estudio de la Fijación Interna (Arbeitsgemeinschaft für Osteosynthesefragen, AO, en alemán) de las fracturas fue: A ­12 (75%); B ­ 2 (12,5%); y C ­ 2 (12,5%). No hubo casos de fractura expuesta. Un total de 9 (56,3%) pacientes fueron operados con placa condilar dinámica, 4 (25%), con placa bloqueada, y 3 (19%), con clavo retrógrado. La mediana de latencia quirúrgica fue de 10 (rango: 3 a 27) días, con una mediana de hospitalización de 14 (rango: 5 a 47) días. Complicaciones fueran presentadas por 6 (37,5%) pacientes: 2 (12,5%) casos de tromboembolismo pulmonar y 4 (25%) casos que requirieron reintervención (2 fallos de osteosíntesis, 1 artrofibrosis y 1 no unión aséptica). No hubo complicaciones infecciosas. La mortalidad a 12 meses fue de 0%. CONCLUSIONES Los pacientes con FFD en esta cohorte geriátrica presentaron una larga estadía hospitalaria, con una alta tasa de complicaciones, que incluye un 25% de reintervenciones. Pese a esto, la mortalidad a 12 meses fue de 0%

INTRODUCTION Distal femoral fractures (DFF) are a relevant problem for public health worldwide. As the population ages, an increase in the rate of these lesions is expected in the next few years. Objective To describe the complications and mortality from DFF in geriatric patients. MATERIALS AND METHODS A descriptive and retrospective study with patients aged 60 years or older who underwent surgery due to DFF. All subjects received treatment in the same trauma center from 2011 to 2015 and underwent a minimum follow-up of 1 year. Patients with incomplete medical records were excluded. We analyzed demographics, radiological findings, local and systemic complications, length of stay, and mortality rates. RESULTS In total, 16 patients met the inclusion criteria; their median age was of 72 (range: 61 to 93) years, and 14 subjects (87,5%) were female. The classification of the Association for the Study of Internal Fixation (Arbeitsgemeinschaft für Osteosynthesefragen, AO, in German) was as follows: A ­ 12 patients (75%); B ­ 2 patients (12.5%); and C ­ 2 patients (12.5%). There were no open fractures. The devices used in the operations included dynamic condylar screw (DCS) plates (9 subjects; 56%), distal femur locking compression plates (LCPs) (4 subjects; 25%), and retrograde distal femoral nails (DFNs) (3 subjects; 19%). The median time until surgery was of 10 (range: 3 to 27) days, with a median length of stay of 14 (range: 5 to 47) days. Complications were presented by 6 (37.5%) patients: 2 (12.5%) cases of pulmonary thromboembolism and 4 (25%) cases which required reintervention (2 due to hardware failure, 1 because of arthrofibrosis, and 1 due to aseptic nonunion); there were no cases of infection. The mortality rate at 12 months was of 0%. CONCLUSION The patients with DFF in this geriatric cohort presented a long length of stay, with a high rate of complications, including a rate of 25% of reintervention. Nevertheless, the 1-year mortality rate was of 0%

Surgical treatment for ipsilateral femoral neck and shaft fracture / 中国骨伤

OBJECTIVE@#To retrospectively analyze efficacy of single structure internal fixation and double structure internal fixation in the treatment of ipsilateral femoral shaft and neck fracture, and analyze their indications.@*METHODS@#From June 2015 to December 2020, 21 patients with ipsilateral femoral shaft and femoral neck fracture were treated, including 14 males and 7 females, aged 23 to 69 years old with an average of(38.1±12.9) years old. According to different femoral shaft fracture sites, some patients were fixed with cephalomedullary implant for both femoral neck and the femoral shaft(single structure, InterTan or PFNA Ⅱ), some patients were fixed with cannulated screws for the femoral neck and a retrograde locking nail for the femoral shaft (dual structure), and postoperative function and complications were recorded during follow-up. In 10 cases of single-structure fixation, the femoral necks were all basicervical fractures, and the femoral shaft fractures were located in the proximal isthmus;11 cases were double-structure fixation, 9 cases in 11 were basal type of femoral neck, 2 cases in 11 were neck type, and the femoral shaft fractures were located in the isthmus and the distal isthmus.@*RESULTS@#All patients were followed up for 12 to 27 months. No femoral head necrosis, deformity, delay or nonunion occurred in the patients with single-structure fixation, and no delayed union or nonunion occurred in femoral shaft fractures;At the final follow-up, Harris score of patients with single-structure fixation was 91.8±4.1, with 8 cases were excellent and 2 cases were good. The fractures of patients with dual-structure fixation achieved good union without femoral head necrosis, except 1 case of femoral shaft fracture had delayed union;At the final follow-up, Harris score of patients with dual-structure fixation was 92.4±5.9, 7 cases were excellent, 3 cases were good, and 1 case was fair.@*CONCLUSION@#Good reduction and fixation is the key to the treatment of such fractures. Both the single-structure fixation and the dual-structure fixation are good methods, and it should be selected according to the locations of femoral shaft and femoral neck fractures. Single-structure fixation is a good choice for femoral shaft fractures located at the proximal isthmus and basal femoral neck fractures. For isthmus and distal femoral shaft fractures combined with ipsilateral femoral neck fractures, dual-structure fixation is recommended.

Disastrous triad of femoral head:femoral neck fracture meeting fracture-dislocation of femoral head / 中国骨伤

Femoral head and ipsilateral femoral neck fractures are serious and complicated injuries, which usually yield unsatisfactory results using conventional hip-preserving surgery. The key point of the management and prognosis mainly lies in femoral neck fractures. An apparent and consecutive relationship exists between femoral neck fractures and femoral head fracture-hip dislocation in such injuries. It is believed that disastrous triad of femoral head (DTFH) could summarize these specific injuries, and reflect the injury mechanism and prognostic characteristics. Based on our clinical observation and literature review, DTFH could be divided into three subgroups:TypeⅠ, common DTFH, in which femoral neck fractures occur following femoral head fractures-hip dislocation due to the same trauma; TypeⅡ, iatrogenic DTFH, in which femoral neck fractures come out in the caring process of femoral head fractures-hip dislocation; Type Ⅲ, stressed DTFH, in which femoral neck fractures occur after the management of femoral head fractures-hip dislocation. In the scenario, the line of femoral neck fractures locates distally to the femoral head fractures. Herein, we will discuss clinical characteristics of these types of DTFH.

An unusual case of symmetric quadruple limb fractures / 中华创伤杂志(英文版)

A 19-year-old man had an accidental fall from the 2nd floor and sustained multiple injuries. On radiological evaluation, the patient had symmetrical quadruple limb involvement with bilateral humerus shaft, bilateral olecranon, bilateral femur shaft, and bilateral patella fractures. The patient was actively managed using damage control orthopaedics, and a sequence of skeletal fixation was planned based on the hemodynamic stability and periodical serum lactate assessment. Symmetrical quadruple limb fractures are very rare, which could be associated with higher mortality. A meticulous clinical evaluation, periodical blood parameter assessment and strict adherence to the principles of damage control orthopaedics can be conducive to prevent life-endangering complications.

Augmenting locking plate with autologous bone graft for the treatment of nonunion of long bone fracture in the lower extremity with retaining of the original intramedullary nail / 中国骨伤

OBJECTIVE@#To explore clinical effect of attaching locking plate with bone grafting based on retaining the original intramedullary nail in treating non-union after intramedullary nail fixation of long shaft fractures of lower limbs.@*METHODS@#A retrospective study was conducted on 20 patients treated with non-union fractures after intramedullary nailing of long shaft fractures of lower limbs from June 2015 to June 2020. All patients were treated with the original intramedullary nailing and bone grafting from the iliac bone, and were underwent open reduction plate internal fixation and bone grafting for old fractures. Among them, 14 were males and 6 were females, aged from 35 to 56 years old with an average of (42.2±9.6) years old. Nine patients were femoral shaft fracture and 11 patients were tibial shaft fracture. According to characteristics of fracture end nonunion, 6 patients were stable/atrophic, 9 patients were unstable/large, and 5 patients were unstable/atrophic. The nonunion time ranged from 8 to 12 months with an average of(9.8±2.0) months after the initial surgery. Visual analogue scale (VAS), knee range of motion, bone healing time, complications and fracture-end healing were recorded before and at the latest follow-up.@*RESULTS@#All patients were followed up for 18 to 48 months with an average of (36.3±10.5) months. The incision of all patients were healed at stageⅠwithout complications such as infection or internal fixation ruptur. Healing time of femur and tibia was (8.5±2.6) months and (9.5±2.2) months. Knee joint motion increased from preoperative (101.05±8.98) ° to postoperative (139.35±8.78) ° at the latest follow-up (t=-12.845, P<0.001). VAS decreased from preoperative (5.15±1.72) to postoperative (0.75±0.96) at the latest follow-up (t=11.186, P<0.001).@*CONCLUSION@#On the basis of retaining the original intramedullary nail, the addition of locking plate internal fixation and autogenous iliac bone grafting have advantages of simple operation, less trauma, fewer complications and high fracture healing rate. It is one of the effective surgical schemes for the treatment of nonunion after intramedullary nail fixation of long bone fracture of lower extremity.

Lesiones ligamentarias de rodilla asociadas a fracturas de diáfisis femoral: epidemiología y diagnóstico: revisión narrativa de la bibliografía / Knee ligamentous injury associated to femoral shatf fracture: epidemiology and diagnosis: narrative review of the literatur / Lesões ligamentares do joelho associadas a fraturas diafisárias do fêmur: epidemiologia e diagnóstico: revisão narrativa da literatura

Introducción: Las fracturas de la diáfisis femoral son lesiones que requieren gran energía y a menudo asocian otras lesiones. Este es el caso de las lesiones ligamentarias de rodilla, las cuales pueden pasar desapercibidas por el equipo médico tratante. El objetivo de nuestro trabajo es revisar la literatura existente sobre esta asociación lesional. Dentro de la misma se buscará la metodología diagnóstica utilizada y la incidencia de las lesiones ligamentarias. Materiales y métodos: Se realizó una búsqueda bibliográfica de forma sistematizada a través de los portales de búsqueda PubMed y Timbó. La búsqueda alcanzó un total de 3099 artículos y de acuerdo a los criterios de inclusión y exclusión se seleccionaron 15 trabajos. Resultados: Los diferentes artículos utilizaron examen físico bajo anestesia, radiografías en estrés, artroscopía o resonancia nuclear magnética para establecer el diagnóstico de las lesiones ligamentarias asociadas a las fracturas de diáfisis femoral. Un 22,5% de las fracturas femorales asoció lesión ligamentaria de rodilla, siendo la lesión del ligamento cruzado anterior el 34% de las lesiones reportadas. Discusión: Se evidencia una gran variabilidad en la incidencia de lesiones ligamentarias y de cuál es el ligamento más frecuentemente lesionado, yendo desde 5,3% a 52,5% en estudios tanto retrospectivos como prospectivos con bajos números de pacientes. Se plantea un algoritmo diagnóstico para los pacientes que puedan presentar esta asociación lesional, para evitar que los mismos pasen desapercibidos al equipo médico tratante. Logrando un diagnóstico precoz se puede mejorar el pronóstico de estos pacientes. Conclusión: De nuestra revisión se desprende que en el contexto de una fractura de diáfisis femoral un 22,5% de los pacientes presenta lesiones ligamentarias de rodilla con un 34% de compromiso del LCA. Sin embargo, estas cifras son muy variables en los distintos trabajos. Por esta razón, creemos necesario llevar a cabo un estudio prospectivo con mayor número de pacientes para lograr valorar la verdadera epidemiología de estas lesiones.

Introduction: Femoral shaft fractures require great energy and are often associated with other injuries. This is the case of knee ligament injuries, which can go unnoticed by the treating physician The objective of our work is to review the existing literature on this injury association. Within it, the diagnostic methodology used and the incidence of ligamentous injuries will be sought. Materials and methods: A bibliographic search was carried out in a systematic way through the search portals PubMed and Timbó. The search reached a total of 3099 articles and according to the inclusion and exclusion criteria, 15 works were selected. Results: The different articles used physical examination under anesthesia, stress radiographs, arthroscopy or magnetic resonance imaging to establish the diagnosis of ligamentous injuries associated with femoral diaphysis fractures. 22.5% of femoral fractures were associated with knee ligament injury, with anterior cruciate ligament accounting for 34% of reported injuries. Discussion: There is evidence of a great variability in the incidence of ligament injuries and which is the most frequently injured ligament, ranging from 5.3% to 52.5% in both retrospective and prospective studies with low numbers of patients. A diagnostic algorithm is proposed for patients who may present this lesional association, to prevent them from going unnoticed by the treating medical team. Achieving an early diagnosis can improve the prognosis of these patients. Conclusion: Our review shows that in the context of a femoral diaphysis fracture, 22.5% of patients present knee ligament injuries with 34% of ACL involvement. However, these figures are highly variable in the different studies. For this reason, we believe it is necessary to carry out a prospective study with a larger number of patients in order to assess the true epidemiology of these lesions.

Introdução: As fraturas da diáfise do fêmur são lesões que requerem grande energia e muitas vezes estão associadas a outras lesões. É o caso das lesões ligamentares do joelho, que podem passar despercebidas pela equipe médica que o trata. O objetivo do nosso trabalho é revisar a literatura existente sobre essa associação lesional. Dentro dele, será buscada a metodologia diagnóstica utilizada e a incidência de lesões ligamentares. Materiais e métodos: Foi realizada uma busca bibliográfica de forma sistemática através dos portais de busca PubMed e Timbó. A busca atingiu um total de 3099 artigos e de acordo com os critérios de inclusão e exclusão, 15 trabalhos foram selecionados. Resultados: Os diferentes artigos utilizaram o exame físico sob anestesia, radiografias de estresse, artroscopia ou ressonância magnética para estabelecer o diagnóstico de lesões ligamentares associadas às fraturas da diáfise do fêmur. 22,5% das fraturas do fêmur foram associadas à lesão ligamentar do joelho, sendo a lesão do ligamento cruzado anterior responsável por 34% das lesões relatadas. Discussão: Há evidências de uma grande variabilidade na incidência de lesões ligamentares e qual é o ligamento mais frequentemente lesado, variando de 5,3% a 52,5% em estudos retrospectivos e prospectivos com baixo número de pacientes. Um algoritmo diagnóstico é proposto para os pacientes que podem apresentar essa associação lesional, para evitar que passem despercebidos pela equipe médica responsável. O diagnóstico precoce pode melhorar o prognóstico desses pacientes. Conclusão: Nossa revisão mostra que no contexto de fratura da diáfise do fêmur, 22,5% dos pacientes apresentam lesões ligamentares do joelho com 34% de envolvimento do LCA. No entanto, esses números são altamente variáveis ​​nos diferentes estudos. Por esse motivo, acreditamos ser necessário realizar um estudo prospectivo com um número maior de pacientes para avaliar a verdadeira epidemiologia dessas lesões.

Systemic ALK-positive anaplastic large cell lymphoma involving implant site: a fortuitous association

Anaplastic lymphoma kinase (ALK) positive, anaplastic large cell lymphoma involving the non-mammary implant is an extremely rare presentation. Irrespective of the type or site, the implant-associated primary ALCL is morphologically and immunophenotypically similar to ALK-negative ALCLs. Herein, we present the case of a 42-year-old male who developed a lytic lesion after an implant for a right femur fracture. The lytic lesion biopsy revealed anaplastic large cell lymphoma with ALK protein expression. Imaging findings showed the widespread dissemination of disease all over the body, entrapping the implant too. ALCL involving the bone implant is a very unusual and rare presentation that needs to be documented.

Prevention of bone infection after open fracture using a chitosan with ciprofloxacin implant in animal model

Abstract Purpose To evaluate different concentrations of ciprofloxacin to prevent infection after open fracture contaminated with S. aureus in rats using absorbable local delivery system. Methods Fifty-two Wistar rats were assigned to six groups. After 4 weeks, all animals underwent 99mTc-ceftizoxima scintigraphy evaluation, callus formation measurement and histological analysis. ANOVA, t-Student and Kruskal Wallis were used for quantitative variables statistical analysis, whereas qui square and exact Fisher were used for qualitative variables. Results Treatment using 25% and 50% of ciprofloxacin incorporated at the fracture fixation device were effective in preventing bone infection compared to control group (p<0.05). Chitosan were not effective in preventing bone infection when used alone compared to control group (p>0.05). Histological findings demonstrated bone-healing delay with 50% of ciprofloxacin. No difference in callus formation were observed (p>0.05). Conclusion Local delivery treatment for contaminated open fracture using chitosan with ciprofloxacin is effective above 25%.

Fatores relacionados ao delirium e à mortalidade em idosos vítimas de fratura de fêmur em uma enfermaria de ortopedia / Factors related to delirium and mortality in older adults with femur fracture on an orthopedic unit

OBJETIVO: Correlacionar as principais características clínicas do idoso internado por fratura de fêmur com a incidência de delirium e mortalidade durante a internação. MÉTODOS: Estudo transversal em pacientes com idade acima de 65 anos internados em enfermaria de ortopedia com fratura de fêmur. Foi aplicada aos pacientes e/ou cuidadores uma entrevista elaborada pelos autores para levantamento de suas características clínicas, sendo posteriormente realizada a correlação entre o perfil e a taxa de delirium e mortalidade. Para análise estatística, foi usado o programa Statistical Package for the Social Sciences (SPSS), o teste t de Student e o teste do χ2. Foi considerado estatisticamente significativo o valor p < 0,05. RESULTADOS: Noventa pacientes com média de idade de 83 anos (65­99), sendo 77,8% mulheres. O tempo médio de internação foi de 19,7 dias, sendo identificado delirium em 39,9% dos pacientes, e a taxa de mortalidade foi de 17,8%. O delirium esteve significativamente associado à idade avançada (p = 0,046), ao uso de psicotrópicos ­ especialmente a quetiapina ­ , à maior taxa de mortalidade, ao diabetes mellitus, à síndrome demencial e à baixa funcionalidade. Mortalidade, por sua vez, apresentou associação com insuficiência renal crônica, menor funcionalidade e síndrome demencial. CONCLUSÃO: Encontramos que o delirium esteve associado a idades mais elevadas, à menor funcionalidade, ao diabetes mellitus, à síndrome demencial, ao maior desfecho de óbitos e ao uso de psicotrópicos; e a mortalidade, à síndrome demencial, à insuficiência renal crônica e à pior funcionalidade.

OBJECTIVE: To correlate the main clinical characteristics of geriatric patients hospitalized for femur fracture with delirium incidence and mortality during hospitalization. METHODS: Cross-sectional study in patients over 65 years old admitted to an orthopedics unit with femoral fracture. The authors interviewed patients and / or caregivers to investigate their clinical characteristics, and subsequently correlate their profiles to the rates of delirium and mortality. Statistical analysis was performed using the Statistical Package for Social Sciences (SPSS), Student's t-test and χ2 test. Significance was established at p < 0.05. RESULTS: Participants included 90 patients with a mean age of 83 years (65­99), 77.8% women. The mean length of stay was 19.7 days, with delirium identified in 39.9% of patients, and a mortality rate of 17.8%. Delirium was significantly associated with advanced age (p = 0.046), use of psychotropic drugs ­ especially quetiapine ­ , higher mortality rate, diabetes mellitus, dementia syndrome, and low functionality. Mortality, in turn, was associated with chronic kidney disease, lower functionality, and dementia syndrome. CONCLUSION: We found that delirium was associated with advanced age, lower functionality, diabetes mellitus, dementia syndrome, higher death outcomes, and the use of psychotropic drugs; and mortality was associated to dementia syndrome, chronic kidney disease, and worse functionality. KEYWORDS: geriatrics; femoral fractures; delirium; mortality.

Defectos óseos segmentarios infectados en huesos largos: tratamiento con técnica de Masquelet / Masquelet technique for the treatment of infected segmental long-bone defects

Introducción: Los defectos óseos segmentarios infectados son entidades de complejo tratamiento. La técnica de Masquelet representa una alternativa para estos casos. El objetivo de este estudio retrospectivo multicéntrico fue mostrar los resultados clínicos y radiográficos obtenidos con esta técnica de reconstrucción en defectos óseos segmentarios infectados de fémur y tibia, caracterizar los defectos tratados y describir los diferentes aspectos de la técnica quirúrgica. Materiales y Métodos: Analizamos a 24 pacientes (14 hombres y 10 mujeres; edad promedio 36.16 años [rango 18-67]) tratados con la técnica de Masquelet, operados entre 2011 y 2016. El seguimiento promedio fue de 16.5 meses (rango 12-27) desde el segundo tiempo quirúrgico. Se analizaron el hueso afectado, la longitud del defecto (en cm), el tiempo de consolidación y el control del proceso infeccioso. Resultados: La longitud del defecto óseo tratado fue, en promedio, de 5,7 cm (rango 3-12), fue superior a 4 cm en el 50% de los casos, el defecto óseo segmentario de mayor tamaño en la tibia fue de 12 cm y de 10 cm en el fémur. Se logró la consolidación ósea, en todos los casos, en 4.5 meses. Un paciente presentó una recidiva del proceso infeccioso a los 12 meses de la consolidación. Conclusiones: La técnica de Masquelet o de la membrana inducida ofrece una alternativa razonable y sencilla para un problema altamente desafiante como son los defectos óseos segmentarios infectados. La tasa de consolidación es superior al 90% aun en casos complejos. Nivel de Evidencia: IV

Introduction: Infected segmental bone defects are challenging conditions, which require a complex treatment. The Masquelet technique is an alternative for these cases. The aim of this retrospective, multicenter study was to show clinical and radiological outcomes achieved with the use of this reconstruction technique in infected femoral and tibial segmental defects in order to characterize the defects treated and describe different aspects of this surgical approach. Methods: We analyzed 24 patients (14 men and 10 women; average age 36.16 years [range 18-67]) treated with the Masquelet technique between 2011 and 2016. The average follow-up was 16.5 months (range 12-27) from the second surgical stage. We analyzed the affected bone, defect length (cm), consolidation time and infection control. Results: Average length of treated bone defect was 5.7 cm (range 3-12), exceeding 4 cm in 50% of the cases. The largest segmental bone defect was 12 cm at the tibia and 10 cm at the femur. Bone consolidation was achieved in all cases, on an average of 4.5 months. One patient presented a recurrent infection 12 months after the successful consolidation. Conclusions: The Masquelet technique, or induced membrane technique offers a reasonable and simple alternative to a highly challenging problem, such as infected segmental bone defects, achieving a consolidation rate greater than 90% even in complex cases. Level of Evidence: IV

Proximal disability and spinal deformity index in patients with proximal femur fractures / Incapacidade funcional e índice de deformidade espinal em pacientes com fratura do fêmur / Discapacidad e índice de deformidad espinal en pacientes con fractura de la parte proximal del fémur

Objective : To evaluate the quality of life related to the spine in patients with proximal femoral fractures. Methods : Study conducted in a tertiary public hospital in patients with proximal femoral fractures caused by low-energy trauma, through the Oswestry Disability Index questionnaire to asses complaints related to the spine at the time of life prior to the femoral fracture. The thoracic and lumbar spine of patients were also evaluated applying the radiographic index described by Gennant (Spinal Deformity Index), which assesses the number and severity of fractures. Results : Seventeen subjects completed the study. All had some degree of vertebral fracture. Patients were classified in the categories of severe and very severe disability in the questionnaire about quality of life. It was found that the higher SDI, the better the quality of life. Conclusion : There is a strong association of disability related to the spine in patients with proximal femoral fracture, and this complaint must be systematically evaluated in patients with appendicular fracture.

Objetivo : Avaliar a qualidade de vida relacionada com a coluna vertebral em pacientes com fratura da parte proximal do fêmur. Métodos : Estudo realizado em um hospital público terciário em pacientes com fraturas do fêmur proximal causado por trauma de baixa energia, por meio de aplicação do questionário Oswestry Disability Index, para avaliar as queixas relacionadas com a coluna vertebral no momento de vida prévio à fratura femoral. Avaliaram-se também as colunas torácica e lombar dos pacientes aplicando-se o índice radiográfico descrito por Gennant (Spinal Deformity Index), que avalia o número e a gravidade das fraturas. Resultados : Dezessete sujeitos concluíram o estudo. Todos apresentaram algum grau de fratura vertebral. Os pacientes enquadraram-se nas categorias de incapacidade severa e muito severa do questionário de qualidade de vida. Verificou-se que quanto maior o SDI, melhor a qualidade de vida. Conclusão : Há forte associação de incapacidade relacionada à coluna vertebral em pacientes e fratura do fêmur proximal, devendo esta queixa ser avaliada sistematicamente em pacientes com a fratura apendicular.

Objetivo : Evaluar la calidad de vida relacionada con la columna vertebral en pacientes con fracturas de la parte proximal del fémur. Métodos : Estudio realizado en un hospital público terciario en pacientes con fracturas femorales proximales causadas por un traumatismo de baja energía, a través del cuestionario Oswestry Disability Index para evaluar las quejas relacionadas con la columna vertebral en el momento de la vida antes de la fractura femoral. También se evaluaron columna torácica y lumbar de los pacientes por el índice radiográfico descrito por Gennant ( Índice de deformidad de la columna), que evalúa el número y la gravedad de las fracturas. Resultados : Diecisiete sujetos completaron el estudio. Todos tenían algún grado de fractura vertebral. Los pacientes fueron clasificados en las categorías de discapacidad grave y severa del cuestionario sobre calidad de vida. Se encontró que cuanto mayor sea el SDI, mejor será la calidad de vida. Conclusión : Hay una fuerte asociación de la discapacidad relacionada con la columna vertebral en pacientes con fractura del fémur proximal y esta queja debe ser evaluada de forma sistemática con fractura apendicular.

Embolia gordurosa no diagnóstico diferencial de “cor pulmonale” agudo: relato de caso / Fat embolism in differential diagnosis of acute cor pulmonale: case report

Embolia gordurosa (EG) é definida como a presença de partículas de gordura na circulação sanguínea as quais têm potencial para gerar fenômenos embólicos e lesão tecidual local, principalmente em pacientes vítimas de traumas e fraturas dos ossos longos. Síndrome de embolia gordurosa (SEG) caracteriza-se pelo surgimento de sinais e sintomas específicos secundários ao acometimento de órgãos-alvo como pulmões, cérebro e pele, na vigência de EGDiscutiremos o caso de uma paciente feminina jovem com síndrome de embolia gordurosa e “cor pulmonale” agudo 48 horas após acidente de trânsito com fratura do fêmur.

Vertebral fractures in patients treated for femur proximal third fractures / Fraturas vertebrais em pacientes tratados de fraturas do terço proximal do fêmur / Fracturas vertebrales en pacientes tratados por fracturas del tercio proximal del fémur

OBJECTIVE: To investigate the prevalence of fractures of the vertebral bodies in patients with femur proximal third fracture. METHODS: Cross-sectional study conducted at Hospital de Clínicas, Unicamp, SP, Brazil, between May and December 2012, which referred the patients with proximal femur fracture to radiographs of the spine. Fractures were evaluated according to number, severity and localization, applying the Genant index. RESULTS: Of the 15 subjects who completed the study, 14 had fractures of the vertebral bodies. The most commonly affected level was T8. There was no increased prevalence of fractures at the apex of the thoracic kyphosis and lumbar lordosis. CONCLUSION: There is strong epidemiological association between femur proximal third fractures and fractures of vertebral bodies caused by insufficiency. .

OBJETIVO: Pesquisar a prevalência de fraturas dos corpos vertebrais em pacientes com fratura do terço proximal do fêmur. MÉTODOS: Estudo transversal realizado no Hospital de Clínicas da Unicamp, SP, Brasil, entre maio e dezembro de 2012, que submeteu os pacientes com fratura do terço proximal do fêmur a radiografias da coluna vertebral. As fraturas foram avaliadas segundo o número, a gravidade e a localização, aplicando-se o índice de Genant. RESULTADOS: Dos 15 sujeitos que concluíram o estudo, 14 tinham fraturas dos corpos vertebrais. O nível mais comumente acometido foi o T8. Não se observou maior prevalência de fratura no ápice da cifose torácica e da lordose lombar. CONCLUSÃO: Existe forte associação epidemiológica entre fraturas do terço proximal do fêmur e fraturas de corpos vertebrais causadas por insuficiência. .

OBJETIVO: Investigar la prevalencia de las fracturas de los cuerpos vertebrales en pacientes con fractura del tercio proximal del fémur. MÉTODOS: Estudio transversal realizado en el Hospital de Clínicas, Unicamp, SP, Brazil, entre mayo y diciembre de 2012, en el cual, los pacientes con fractura del tercio proximal del fémur fueron sometidos a radiografías de la columna vertebral. Las fracturas se evaluaron de acuerdo con el número, la gravedad y la localización, aplicando el índice de Genant. RESULTADOS: De los 15 sujetos que completaron el estudio, 14 tenían fracturas de los cuerpos vertebrales. El nivel más afectado fue T8. No hubo aumento de la prevalencia de fracturas en el vértice de la cifosis torácica y lordosis lumbar. CONCLUSIÓN: Existe una fuerte asociación epidemiológica entre las fracturas del tercio proximal del fémur y las fracturas de los cuerpos vertebrales causadas por insuficiencia. .

Pseudoaneurysm of the superficial femoral artery; following of the fracture shaft of femur with condylar buttress plate

The case report is of a 30-year male patient who had a fracture shaft of femur and after open reduction and internal fixation developed swelling which was painful and was present on the medial aspect of the thigh. It was decided to do an angiogram as the swelling was expansile and confirmed superficial femoral artery pseudo aneurysm and the reason was thought to be over penetration of the bit of the drill while doing the surgery for shaft of femur fracture. Treatment decided by the multidisciplinary team was to remove the condylar buttress plate, resection of the aneurysm and repair of the aneurysm with inter-positional graft

Rescate de clavos endomedulares mediante estabilización con placas / Intramedullary nail rescue with plate stabilization

Introducción: La seudoartrosis de fémur es una complicación poco frecuente luego del enclavado endomedular. Existe controversia sobre el tratamiento que genera mejores resultados luego de esta complicación. En casos específicos, las no uniones femorales pueden ser correctamente tratadas mediante estabilización con placas sobre el clavo endomedular previo. Materiales y Métodos: Estudio retrospectivo de 16 seudoartrosis diafisarias (12 atróficas, 4 hipertróficas), asépticas de fémur tratadas inicialmente con clavo endomedular. Abordaje lateral de fémur para la osteosíntesis con placa. En todos los casos, se conservó el clavo endomedular colocado antes. En 12 pacientes, se realizó descorticación en el foco de no unión con colocación de injerto óseo autólogo; en 3 de ellos, se colocaron también factores de crecimiento. En 4 pacientes, se colocó la placa sin el agregado de injerto. Resultados: Todas consolidaron en 5,3 meses promedio desde la osteosíntesis con placa, sin cirugías adicionales. Un paciente sufrió una infección posquirúrgica que se curó con tratamiento antibiótico oral. Conclusiones: El cambio de clavo endomedular es el método de elección para la mayoría de las seudoartrosis diafisarias, asépticas de fémur, pero es más complejo de realizar en seudoartrosis metafisarias, en seudoartrosis atróficas con importante defecto óseo y cuando el clavo colocado previamente es el de mayor diámetro posible. La placa proporciona compresión y estabilidad del foco de fractura, y resulta una buena alternativa para tratar esta complicación. Recomendamos mínimo desbridamiento de partes blandas y descorticación que se limite sólo al foco de la no unión...

Background: Femoral nonunion is a rare complication after intramedullary nailing. There is controversy about the best treatment option. In specific cases, femoral nonunions can be successfully treated by stabilization with plates over an intramedullary nail. Methods: Retrospective review of 16 femur nonunions previously treated with intramedullary nails (12 atrophic, 4 hypertrophic). Lateral approach was used for plate fixation. Previous intramedullary nail was maintained in all cases. Twelve patients underwent osteoperiosteal decortication and autologous bone graft; in 3 of them platelet growth factors were added. In 4 hypertrophic nonunions, no bone graft was added to plate osteosynthesis. Results: Average healing time was 5.3 months after plate fixation. No additional surgeries were needed. One patient suffered a superficial wound infection successfully treated with oral antibiotics. Conclusions: Exchange of intramedullary nail is the method of choice for most aseptic nonunions of femoral diaphysis, but this technique is more demanding in metaphyseal nonunions, in atrophic nonunions with bone defects, and when the biggest intramedullary nail is already in place. Plate provides compression and stability to the fractures, being a good alternative to treat this complication. Minimal debridement of soft tissue and decortication limited to the nonunion is recommended...

Abordagem anestésica em paciente pediátrico com síndrome de Leigh / Anesthetic management of a pediatric patient with Leigh syndrome / Abordaje anestésico en paciente Pediátrico con el síndrome de Leigh

JUSTIFICATIVA E OBJETIVOS: A síndrome de Leigh (SL) é uma doença rara causada por anomalias na produção de energia mitocondrial. O sistema nervoso central é afetado com mais frequência, com retardo psicomotor, convulsões, nistagmo, oftalmoparesia, atrofia óptica, ataxia, distonia ou insuficiência respiratória. Os procedimentos cirúrgicos e anestésicos provocam irritabilidade traqueal e podem exacerbar os riscos de aspiração, sibilação, dificuldade respiratória, respiração ofegante, hipoventilação e apneia. RELATO DE CASO: Apresentamos uma abordagem anestésica usada em um menino de seis anos com a forma grave de SL que envolve reparação de uma fratura de fêmur. Propofol e remifentanil foram infundidos para anestesia geral. O paciente foi atentamente monitorado durante a anestesia e sua permanência na unidade de terapia intensiva no período pós-operatório inicial. CONCLUSÕES: Uma atenta monitoração intraoperatória dos pacientes, que inclui pressão arterial invasiva e mensurações frequentes da gasometria, glicose e lactato, faz esse procedimento transcorrer sem problemas. A terapia intensiva e a assistência respiratória ao paciente com SL sob sedação, com uma combinação de analgésicos durante o período pós-operatório inicial, minimizaram a resposta ao estresse causado pela dor pós-cirúrgica.

BACKGROUND AND OBJECTIVES: Leigh syndrome (LS) is a rare disease caused by abnormalities of mitochondrial energy generation. The central nervous system is most frequently affected, with psychomotor underdevelopment, seizures, nystagmus, ophthalmoparesis, optic atrophy, ataxia, dystonia, or respiratory failure. Surgical and anesthetic procedures stimulate the tracheal irritability, and could exacerbate risks of aspiration, wheezing, breathing difficulties, gasping, hypoventilation, and apnea. CASE REPORT: We present the anesthetic management for a six-year-old boy with severe form of LS, involving repair of a femur fracture. Propofol and remifentanil were infused for general anesthesia. The patient was closely monitored during anesthesia and in the intensive care unit in the early postoperative period. CONCLUSIONS: Close intraoperative monitoring of patients, including invasive arterial blood pressure monitoring and frequently measuring the levels of blood gases, glucose, and lactate, made this procedure run smoothly. Intensive care and breathing support for the patient with LS, under sedation with an analgesic combination during the early postoperative period, minimized the stress response due to pain after surgery.

JUSTIFICATIVA Y OBJETIVOS: El síndrome de Leigh (SL) es una enfermedad rara causada por anomalías en la producción de energía mitocondrial. El sistema nervioso central está afectado más a menudo, con el retardo psicomotor, convulsiones, nistagmo, oftalmoparesia, atrofia óptica, ataxia, distonía o insuficiencia respiratoria. Los procedimientos quirúrgicos y anestésicos provocan irritabilidad traqueal y pueden exacerbar los riesgos de aspiración, sibilancias, dificultad respiratoria, respiración extenuante, hipoventilación y apnea. RELATO DE CASO: Presentamos un abordaje anestésico usado en un niño de 6 años, con la forma grave de SL que nos ocupa con la reparación de una fractura de fémur. El propofol y el remifentanilo se infundieron para la anestesia general. El paciente fue monitoreado con mucho cuidado durante la anestesia y durante su permanencia en la unidad de cuidados intensivos en el período postoperatorio inicial. CONCLUSIONES: Una meticulosa monitorización intraoperatória de los pacientes, que incluye monitorización de presión arterial invasiva y mensuraciones frecuentes de la gasometría, glucosa y lactato, posibilita el perfecto transcurso del procedimiento. Los cuidados intensivos y la asistencia respiratoria al paciente con SL bajo sedación con una combinación de analgésicos durante el período postoperatorio inicial, minimizaron la respuesta al estrés causado por el dolor postquirúrgico.

Rodilla flotante en adultos: 30 años de revisión / Floating knee in adults: a 30 years review

La rodilla flotante es la asociación simultánea de fracturas ipsilaterales del fémur y la tibia que incluye una combinación de fracturas diafisiarias, metafisiarias e intraarticulares. Su tratamiento representa un reto terapéutico. Se realizó un estudio retrospectivo, analítico, observacional de cohorte hospitalaria conducido en un centro de IV nivel. Se incluyeron todos los pacientes de ambos sexos con edad igual o mayor a 16 años, que ingresaron con diagnóstico de rodilla flotante, desde enero 1980 a diciembre 2010. Se incluyeron 314 pacientes. 71 % de sexo masculino y edad promedio de 28,22 años. El grupo etario de 16-25 años fue el más afectado. 66% fueron abiertas. Los accidents automovilísticos fueron la causa en 92% de los casos. 58% fueron tipo I de Fraser. La técnica quirúrgica que se relacionó con los mejores resultados clínicos y radiológicos al término del seguimiento fue el enclavado endomedular bloqueado tanto para el fémur como para la tibia. La tasa de infección fue 14% y mortalidad del 6%(AU)

A floating knee is the simultaneous ipsilateral association fractures of the femur and tibia which includes a combination of diaphyseal, metaphyseal and intraarticular fractures. lts an high-energy injury caused trauma and is associated with high risk of morbidity and mortality. Treatment of floating knee representa a therapeutic challenge. We performed a prospective, analytic cohort observational hospital conducted a level IV center. We included all patients of both sexes, aged greater than or equal to 16 years, admitted with the diagnosis of knee Floating Hospital Universitario de Los Andes, from January 1980 to December 2010. 314 patients were found. 71 % were male and mean age 28.22 years. The age group 16-25 years was the most affected. 66% were open. The cause was motor vehicle accidents in 92% of cases. 58% were type I Fraser. The surgical technique was associated with better clinical and radiological follow-up was at the end of the locked intramedullary nailing both the femur and tibia for. The infection rate was 14% and mortality of 6%(AU)