RESUMO
Abstract@#Alzheimer's disease (AD) is a neurodegenerative disease characterized by deposition of β-amyloid (Aβ). Liver X receptors (LXRs), a member of the nuclear receptor transcription factor superfamily, are widely expressed in brain, which may be involved in the development and progression of AD. Based on the international and national publications pertaining to the association between LXRs and AD from 2010 to 2022, this review summarizes the advances on the involvement of LXRs in the regulation of cholesterol metabolism, inflammatory response and synapse formation in the pathogenesis of AD was reviewed, so as to provide insights into the prevention and treatment of AD.
RESUMO
Live Yeast Cell Derivative (LYCD) was based on a living cells response to a controlled injury, which stimulated it to produce protective substance to increase cellular respiration and wound healing The experiment suggested that LYCD had the ability to improve cellular respiration, and this ability became strongest after the cell was treated with H 2O 2 for 15min, while the quantity of reduced glutathione (GSH) in LYCD reached the highest at 30min By contrast, almost the same biological activity of LYCD was observed under different stress conditions