RESUMO
Epilepsy, one of the most common neurological diseases, is usually accompanied by anxiety, depression, cognitive disorders and other neuropsychiatric comorbidities. Current therapies are not effective in patients with drug-resistant and psychoneurotic comorbidities, so it is necessary to find new therapeutic approaches to address this challenge. Stem cells have good application basis in epilepsy for their characteristics of self-renewal, multidirectional differentiation, existence in a variety of tissues, participating in tissue regeneration and repair. This review focuses on the research progress of stem cells in epilepsy and epileptic neuropsychiatric comorbidity, in order to provide some references for subsequent clinical application in this field.