Interval of ≤2 weeks between 12-core prostate biopsy and laparoscopic radical prostatectomy does not affect perioperative parameters or surgical outcomes / 中华男科学杂志

<p><b>Objective</b>To determine whether a short interval (≤2 weeks) between 12-core prostate biopsy and laparoscopic radical prostatectomy (LRP) affects perioperative parameters and the outcome of surgery.</p><p><b>METHODS</b>This retrospective study included 102 cases of prostate cancer treated by LRP after 12-core prostate biopsy from January 2012 to December 2016. Based on the interval between prostate biopsy and LRP, we divided the patients into three groups: ≤2 wk (n = 35), >2－6 wk (n = 21), and >6 wk (n = 46). The patients averaged 69.87 (59－84) years in age, 24.99 (15.62－33.14) kg/m2 in the body mass index (BMI), 24.41 (0.41－111.78) μg/L in the baseline PSA level, 56.05 (15.97－216.52) ml in the prostate volume, and 7.51 (6－9) in the Gleason score. We analyzed the clinical data, perioperative parameters and outcomes of surgery, and compared them among the three groups of patients.</p><p><b>RESULTS</b>Operations were completed successfully in all the 102 cases without transferring to open surgery. There were no statistically significant differences among the three groups of patients in age, BMI, baseline PSA level, prostate volume, Gleason score, or T stage, nor in the operation time, estimated intraoperative blood loss, blood transfusion rate, intestinal injury, positive incision margin rate, or urinary continence rate at 3 months after surgery.</p><p><b>CONCLUSIONS</b>Laparoscopic radical prostatectomy at ≤2 weeks after 12-core prostate biopsy is safe and effective in the treatment of prostate cancer and does not affect the perioperative parameters and outcomes of surgery.</p>

Laparoscopic radical prostatectomy for prostate cancer found in transurethral resection of the prostate: Report of 14 cases / 中华男科学杂志

Objective@#To sum up the experience in the treatment of prostate cancer found in transurethral resection of the prostate (TURP) by laparoscopic radical prostatectomy (LRP).@*METHODS@#Fourteen patients found with prostate cancer during TURP underwent LRP in our hospital between 2011 and 2016. We reviewed our experience in the treatment and analyzed the clinical and follow-up data.@*RESULTS@#LRP was successfully performed in all the cases at 1－4 months after TURP, with a mean operation time of (113 ± 94) min (80－220 min), a mean blood loss of (188 ± 152) ml (100－500 ml), a mean catheterization time of (11.7 ± 3.7) d (7－16 d), and a median follow-up time of 28 (4－68) months. There were no rectal injuries, conversion to open surgery, or blood transfusion during the operation. Positive surgical margin was found in 1 case, in which the tumor involved the nerve and vessel, and lymphatic fistula occurred in another. Urinary continence was desirable in 13 cases at 12 months after surgery, and no incontinence was observed in the other, which had been followed up for less than 12 months. The patient with positive surgical margin received radiotherapy and endocrine therapy postoperatively and was still alive without pathologic progression. No biochemical or clinical recurrence was found in the other 13 cases.@*CONCLUSIONS@#LRP at 1 month after TURP can provide a proper anatomical plane, make the operation easier, and achieve a satisfactory functional and oncological prognosis for patients with prostate cancer.