RESUMO
This study explored the comorbidity mechanisms of coronary heart disease and depression from the perspectives of "constraint causing disease" and "disease causing constraint", for which "constraint" is the link, and the key lies in the stagnation of qi. The heart storing manifestations in traditional Chinese medicine (TCM) encompasses most physiological processes of the circulatory system, the mental nervous system, and some functions of the endocrine system, and cardiovascular diseases and psychological disorders are closely related to it. In TCM, it is proposed that the stagnation of heart yang leading to "yang deficiency" is the pathogenesis of chest tightness, and emotional disturbance leading to the stagnation of yang qi aggravates the chest tightness, reflecting the process of "disease causing constraint". As the disease progresses, the appearance of phlegm and stasis further worsens the condition, reflecting the process of "constraint causing disease". Based on modern medical understanding, the abnormal accumulation of lipids, platelets, oxidative products, cytokines, and other substances constitute a form of "constraint", which is also the material basis for the comorbidity of coronary heart disease and depression. These substances promote neuronal damage or apoptosis in the emotional and cognitive regions, inducing the onset of depression, reflecting the process of "disease causing constraint". Meanwhile, adverse emotions lead to sympathetic nerve excitement, resulting in the production of catecholamines, promoting platelet aggregation, elevating levels of inflammatory markers, and increasing the risk of coronary heart disease, reflecting the process of "disease causing constraint".
RESUMO
【Objective】 To investigate the effect of blood donation related self-efficacy on blood donation intention, in order to provide valuable reference for formulating the recruitment and service strategy for blood donors with different demographic characteristics. 【Methods】 A questionnaire was designed based on psychological self-efficacy theory, and respondents in Nanchong city were taken as the research objects. The data of demographic characteristics, blood donation related self-efficacy measurement and blood donation intention measurement of the respondents who were randomly selected by convenient sampling method were collected and analyzed by rank sum test. 【Results】 The number of previous blood donation was significantly correlated with blood donation related self-efficacy and blood donation intention, and there was a strong positive correlation between blood donation related self-efficacy and blood donation intention (r=0.618). There are significant differences in blood donation related self-efficacy or blood donation intention of respondents with different blood donation experiences (P0.05). 【Conclusion】 Blood donation intention can be increased by enhancing the blood donation related self-efficacy of respondents. We can focus on the recruitment of respondents with high self-efficacy in the areas covered by the survey during the practice of blood donor recruitment and service to achieve higher recruitment efficiency. In the meantime, special attention should also be paid to the people with relatively low self-efficacy and high-quality services should be provided t to expand blood donor team. Furthermore, blood donor recruitment and services can be appropriately expanded to the countryside as needed.