Effect of glycosaminoglycans with different degrees of sulfation on chondrogenesis / 华西口腔医学杂志

OBJECTIVES@#This study aims to investigate the effects and mechanisms of chondroitin sulfate (CS), dermatan sulfate (DS), and heparin (HEP) on chondrogenesis of murine chondrogenic cell line (ATDC5) cells and the maintenance of murine articular cartilage in vitro.@*METHODS@#ATDC5 and articular cartilage tissue explant were cultured in the medium containing different sulfated glycosaminoglycans. Cell proliferation, differentiation, cartilage formation, and mechanism were observed using cell proliferation assay, Alcian blue staining, real-time quantitative polymerase chain reaction (RT-qPCR), and Western blot, respectively.@*RESULTS@#Results showed that HEP and DS primarily activated the bone morphogenetic protein (BMP) signal pathway, while CS primarily activated the protein kinase B (AKT) signal pathway, further promoted ATDC5 cell proliferation and matrix production, and increased Sox9, Col2a1, and Aggrecan expression.@*CONCLUSIONS@#This study investigated the differences and mechanisms of different sulfated glycosaminoglycans in chondrogenesis and cartilage homeostasis maintenance. HEP promotes cartilage formation and maintains the normal state of cartilage tissue in vitro, while CS plays a more effective role in the regeneration of damaged cartilage tissue.

Application research of standardized communication model / 中国实用护理杂志

Ensuring the safety of patients is the the duty of medical workers. Nursing safety is the key factor to reflect the quality of nursing service, which is closely related to patient safety. The effective communication between physicians and nurses is a powerful guarantee for the safety of patients. The positive effect of SBAR communication model in clinical communication has been validated in many aspects, which gradually becomes an important communication model. Now reviews the origin, connotation, characteristics and application status of SBAR communication model, then put forward the matters needing attention when using the model, in order to provide theoretical reference for clinical application.

The self-directed learning readiness status and influencing factors of practice nursing students / 中国实用护理杂志

Objective To provide basis for clinical teaching methods and course system,this article analyzed practice nursing students self-directed learning readiness status and its influencing factors.Methods The report surveyed a total of 240 nursing students in Zhengzhou University,the Peking Union Medical College by using the general information questionnaire,the Chinese version of Nursing SelfDirected Learning Readiness Scale and The Questionnaire of Clinical Teaching.The total score of the practice nursing students' self-directed learning readiness was obtained on the basis of quantitative analysis,and in this paper,the development and research status had been summarized through document analysis.Results The total score of the practice nursing students' self-directed learning readiness was (116.59±21.79) scores.The influencing factors of practice nursing students' self-directed learning readiness included:whether the students like nursing major,whether perception learning difficulties,whether having the experience of group learning,and the satisfaction to clinical teachers,curriculum system optimization.Conclusions Currently practice nursing students self-learning readiness is relatively low and have many influencing factors.A targeted training should be taken during the clinical teaching and the course system should be optimized to improve the practice nursing students' self-directed learning readiness.

Health check-up intent and policy making of residents living in Shanghai / 中华健康管理学杂志

Objective To conduct a health check-up intention analysis to understand residents' altitude to health eheck-up. Methods A total of 3600 residents living in Shanghai completed the selfdesigned questionnaire. Results About 35.2% participants received health check-up onee per year. In 36 to 60 or > 60 age group, the figure was increased up to 62.6% or 50. 4%, respectively. Public institution employees and those with medical insurance were found to have the highest rate of health checkup. Conclusion Our investigation results suggest that government leadership,health management model and contents, and personnel training should be improve.

Study on policies to implement proper technology of traditional Chinese medicine in communities in central city of Shanghai / 中华全科医师杂志

We studied policies of traditional Chinese medicine (TCM) on four levels ( national,Shanghai city, Pudong New District and community health services (CHS)) from 2008 to 2009 with the method of literature review,questionnaire survey and group interview. 18 national, 5 Shanghai's, 4 Pudong New District's and 87 CHS' TCM related policies were identified. By defining the development target,financial capability, human resource and proper technology of TCM care, those policies ensured and prompted the progression of community TCM services. Yet TCM policy fulfill in community remained lagged,and talent cultivating, medical insurance support and TCM participating in public health needed to be improved.

Rehabilication research of mentally ill in community health service organization based on health management / 中华健康管理学杂志

Objective To evaluate the present rehabilitation status of mentally ill patients at community health service centers in Shanghai. Method Investigation on mental disorder network, present prevalence, community disease classification, and cost-effect assessment was conducted in 201 health service centers in Shanghai in 2007. Result Working condition, staff-member constitution, and finical investment were unoptimistic. However, the community health service centers consider the outcomes of community rehabilitation and management were satisfactory. Conclusion It should be necessary to facilitate the development of community mental health service system, achieve various community rehabilitation and health care, and improve social security system of community healthcare providers.